Program in Gene Function and Expression; Program in Systems Biology; Department of Biochemistry and Molecular Pharmacology
Repressor Proteins; DNA-Binding Proteins; Chromosomal Proteins, Non-Histone; Neurons; Gene Expression Regulation
Genetics and Genomics
In the brain neurons form extensively intermingled projections and synaptic interactions between them. To achieve proper neural connectivity, interactions between sections belonging to the same neuron are avoided. However, how can a cell tell, when it encounters another neuronal projection, whether it is part of the same cell? In other words, how do neurons become self-aware?
Rights and Permissions
Publisher PDF posted as allowed by the publisher's author rights policy at http://www.pnas.org/site/misc/authorfaq.shtml.
DOI of Published Version
Proc Natl Acad Sci U S A. 2012 Jun 5;109(23):8799-800. Epub 2012 May 21. Link to article on publisher's site
Proceedings of the National Academy of Sciences of the United States of America
Dekker, Job, "CTCF and cohesin help neurons raise their self-awareness" (2012). Program in Gene Function and Expression Publications and Presentations. 192.