Program in Gene Function and Expression
Animals; Chromatin; Chromosomes; DNA, Plant; Humans; Meiosis; Mitosis; Models, Biological; Nucleic Acid Conformation; Stress, Mechanical; Time Factors
Genetics and Genomics
We propose that chromosome function is governed by internal mechanical forces generated by programmed tendencies for expansion of the DNA/chromatin fiber against constraining features.
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Copyright © 2004, The National Academy of Sciences
Publisher PDF posted as allowed by the publisher's author rights policy at http://www.pnas.org/site/misc/authorfaq.shtml.
DOI of Published Version
Proc Natl Acad Sci U S A. 2004 Aug 24;101(34):12592-7. Epub 2004 Aug 6. Link to article on publisher's site
Proceedings of the National Academy of Sciences of the United States of America
Kleckner, Nancy; Zickler, Denise; Jones, Gareth H.; Dekker, Job; Padmore, Ruth; Henle, Jim; and Hutchinson, John N., "A mechanical basis for chromosome function" (2004). Program in Gene Function and Expression Publications and Presentations. 139.