UMMS Affiliation

Program in Gene Function and Expression

Publication Date

2004-08-24

Document Type

Article

Subjects

Animals; Chromatin; Chromosomes; DNA, Plant; Humans; Meiosis; Mitosis; Models, Biological; Nucleic Acid Conformation; Stress, Mechanical; Time Factors

Disciplines

Genetics and Genomics

Abstract

We propose that chromosome function is governed by internal mechanical forces generated by programmed tendencies for expansion of the DNA/chromatin fiber against constraining features.

Rights and Permissions

Copyright © 2004, The National Academy of Sciences

Publisher PDF posted as allowed by the publisher's author rights policy at http://www.pnas.org/site/misc/authorfaq.shtml.

DOI of Published Version

10.1073/pnas.0402724101

Source

Proc Natl Acad Sci U S A. 2004 Aug 24;101(34):12592-7. Epub 2004 Aug 6. Link to article on publisher's site

Journal/Book/Conference Title

Proceedings of the National Academy of Sciences of the United States of America

Related Resources

Link to Article in PubMed

PubMed ID

15299144

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