Classes of depression, anxiety, and functioning in acute coronary syndrome patients

UMMS Affiliation

Department of Pediatrics; Department of Psychiatry; Center for Health Policy and Research



Document Type


Medical Subject Headings

Acute Coronary Syndrome; Adaptation, Psychological; Age Factors; Anxiety; Cognitive Therapy; Depression; Female; Humans; Male; Middle Aged; Models, Psychological; Psychiatric Status Rating Scales; Sex Factors


Pediatrics | Psychiatry


OBJECTIVES: To describe change in subgroups characterized by patterns of depression, anxiety, and functional impairment; examine treatment effects on subgroup membership; examine effects of sex and age on subgroup membership.

METHODS: Latent class models were used to meet the first 2 objectives using 79 patients with depression/anxiety. Generalized estimating equations were used to meet the third objective.

RESULTS: Three subgroups characterized by different combinations of psychiatric disorders and functioning were identified. Patients who received treatment were more likely to transition to a less impaired subgroup.

CONCLUSIONS: Unique information about holistic treatment effects can be gained when multiple outcomes are considered simultaneously.

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Citation: Am J Health Behav. 2012 Jan;36(1):20-30. doi:10.5993/AJHB.36.1.3

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