Duchenne Muscular Dystrophy: the Heart of the Matter
Department of Pediatrics
Cardiovascular Diseases | Congenital, Hereditary, and Neonatal Diseases and Abnormalities | Musculoskeletal Diseases | Nervous System Diseases | Pediatrics
PURPOSE OF REVIEW: Duchenne muscular dystrophy is one of many neuromuscular disorders, but it frequently causes severe disability early in life and early death. Cardiac involvement is an important cause of morbidity and mortality.
RECENT FINDINGS: Heart disease in Duchenne muscular dystrophy can include a cardiomyopathy leading to end-stage heart failure along with associated supraventricular and ventricular arrhythmias. This article reviews the diagnosis and treatment of heart disease in Duchenne muscular dystrophy as well as emerging therapies.
Cardiomyopathy, Duchenne muscular dystrophy, Heart failure, Neuromuscular
DOI of Published Version
Shih JA, Folch A, Wong BL. Duchenne Muscular Dystrophy: the Heart of the Matter. Curr Heart Fail Rep. 2020 Jun;17(3):57-66. doi: 10.1007/s11897-020-00456-0. PMID: 32270339. Link to article on publisher's site
Current heart failure reports
Shih J, Folch A, Wong BL. (2020). Duchenne Muscular Dystrophy: the Heart of the Matter. Pediatric Publications. https://doi.org/10.1007/s11897-020-00456-0. Retrieved from https://escholarship.umassmed.edu/peds_pp/303