Title

Neutropenia in the age of genetic testing: Advances and challenges

UMMS Affiliation

Department of Pediatrics, Division of Hematology Oncology

Publication Date

2019-03-01

Document Type

Article

Disciplines

Congenital, Hereditary, and Neonatal Diseases and Abnormalities | Diagnosis | Hematology | Hemic and Lymphatic Diseases | Medical Genetics

Abstract

Identification of genetic causes of neutropenia informs precision medicine approaches to medical management and treatment. Accurate diagnosis of genetic neutropenia disorders informs treatment options, enables risk stratification, cancer surveillance, and attention to associated medical complications. The rapidly expanding genetic testing options for the evaluation of neutropenia have led to exciting advances but also new challenges. This review provides a practical guide to germline genetic testing for neutropenia.

DOI of Published Version

10.1002/ajh.25374

Source

Am J Hematol. 2019 Mar;94(3):384-393. doi: 10.1002/ajh.25374. Epub 2019 Jan 8. Link to article on publisher's site

Journal/Book/Conference Title

American journal of hematology

Related Resources

Link to Article in PubMed

PubMed ID

30536760

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