UMMS Affiliation

Department of Dermatology; Department of Pathology; Department of Pediatrics

Publication Date


Document Type



Dermatology | Pediatrics | Skin and Connective Tissue Diseases


We report a case of Noonan syndrome with loose anagen hair (NS/LAH), a rare variant of Noonan syndrome, with associated trichorrhexis nodosa and trichoptilosis. The SHOC2 mutation may be responsible for these additional hair shaft defects, revealing the importance of microscopic examination of hairs in these patients.


Noonan syndrome with loose anagen hair, trichoptilosis, trichorrhexis nodosa

Rights and Permissions

© 2017 The Authors.

DOI of Published Version



Clin Case Rep. 2017 Jul; 5(7): 1152–1154. doi: 10.1002/ccr3.1011. Link to article on publisher's site

Journal/Book/Conference Title

Clinical case reports

Related Resources

Link to Article in PubMed

PubMed ID


Creative Commons License

Creative Commons Attribution-Noncommercial-No Derivative Works 4.0 License
This work is licensed under a Creative Commons Attribution-Noncommercial-No Derivative Works 4.0 License.



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