L-transposition of the great arteries

UMMS Affiliation

Department of Pediatrics

Publication Date


Document Type



Transposition of Great Vessels


Cardiology | Cardiovascular Diseases | Congenital, Hereditary, and Neonatal Diseases and Abnormalities | Pediatrics


Summary: Levo- or L-looped transposition of the great arteries (L-TGA) is a rare form of congenital heart disease characterized by atrioventricular and ventriculoarterial discordance. It is also commonly referred to as congenitally corrected TGA, double discordance, or ventricular inversion. L-TGA usually does not present with cyanosis unless there are associated cardiac defects. Isolated L-TGA is "physiologically corrected" because systemic deoxygenated venous blood returns to the pulmonary circulation and oxygenated pulmonary venous blood returns to the systemic circulation. Patients with L-TGA are at increased risk for heart failure as adults due to progressive decline in systemic right ventricular function. The pathophysiology, clinical features, diagnosis and management of L-TGA will be presented here.


Fulton DR, Kane DA: L-transposition of the great arteries. Up-To-Date, updated: Jul 19, 2012.

Information in this description reflects the version accessed September 25, 2012: "Literature review current through: Aug 2012. | This topic last updated: Jul 19, 2012."

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