UMMS Affiliation

Department of Pediatrics



Document Type


Medical Subject Headings

Deamino Arginine Vasopressin; Nocturnal Enuresis; Hyponatremia


Nephrology | Pediatrics


Recently, several cases of seizure secondary to hyponatremia have been reported in children treated with intranasal DDAVP1), 2). This has rarely been reported with the oral form. Should the intranasal form be banned for the treatment of nocturnal enuresis (NE)? Or should any form of DDAVP be banned? What are the precautions to take to avoid such an event? We hereunder summarize the literature on the subject, and present the recommendations of the Swiss Group for Pediatric Nephrology and the current position of Swiss medic.


Citation: Cachat F (for the Swiss Group of Pediatric Nephrology): Synthetic DDAVP for Nocturnal Enuresis and the Risk of Symptomatic Hyponatremia: Which Treatment Now? Which Form? Paediatrica 18(6):54-56, 2007.

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