Guidelines for antithrombotic therapy in pediatric patients

UMMS Affiliation

Department of Pediatrics



Document Type


Medical Subject Headings

Causality; Child; Fibrinolytic Agents; Humans; Practice Guidelines as Topic; Thromboembolism; *Thrombolytic Therapy


Hematology | Oncology | Pediatrics


Because of the relatively low incidence of TEs in children, the diagnostic and therapeutic approaches used are largely extrapolated from guidelines for adults. Features that differ in children compared with adults include underlying disorders, high incidence of CVL-related DVT in the upper venous system, and response to SH, warfarin, and thrombolytic agents. There is a paucity of information on the risk/benefit ratio of the therapeutic interventions and long-term outcome. Clinical trials are urgently needed to clarify optimal management for pediatric patients with TEs.

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Citation: J Pediatr. 1998 Apr;132(4):575-88. doi 10.1016/S0022-3476(98)70343-9

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