Title
Cellulose as a matrix for nucleic acid purification
UMMS Affiliation
Department of Pediatrics; New England Newborn Screening Program
Publication Date
1999-02-15
Document Type
Article
Subjects
Cellulose; DNA
Disciplines
Genetics and Genomics | Medical Genetics | Pediatrics
Abstract
Nucleic acid purification is an essential but tedious step in molecular biology studies, which has been made easier since the introduction of solid binding matrix. However, the application of each type of available matrix is often limited to a specific group of nucleic acids. We have discovered a matrix, secondary fibril-associated cellulose (designated as SFcellulose), that can be used as a general-purpose matrix to isolate a wide range of nucleic acids with high yield and quality.
DOI of Published Version
10.1006/abio.1998.2987
Source
Anal Biochem. 1999 Feb 15;267(2):415-8. Link to article on publisher's site
Journal/Book/Conference Title
Analytical biochemistry
Related Resources
PubMed ID
10036150
Repository Citation
Su X, Comeau AM. (1999). Cellulose as a matrix for nucleic acid purification. Genetics. https://doi.org/10.1006/abio.1998.2987. Retrieved from https://escholarship.umassmed.edu/peds_genetics/1