Title

Cellulose as a matrix for nucleic acid purification

UMMS Affiliation

Department of Pediatrics; New England Newborn Screening Program

Publication Date

2-15-1999

Document Type

Article

Subjects

Cellulose; DNA

Disciplines

Genetics and Genomics | Medical Genetics | Pediatrics

Abstract

Nucleic acid purification is an essential but tedious step in molecular biology studies, which has been made easier since the introduction of solid binding matrix. However, the application of each type of available matrix is often limited to a specific group of nucleic acids. We have discovered a matrix, secondary fibril-associated cellulose (designated as SFcellulose), that can be used as a general-purpose matrix to isolate a wide range of nucleic acids with high yield and quality.

DOI of Published Version

10.1006/abio.1998.2987

Source

Anal Biochem. 1999 Feb 15;267(2):415-8. Link to article on publisher's site

Journal/Book/Conference Title

Analytical biochemistry

Related Resources

Link to Article in PubMed

PubMed ID

10036150

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