Cellulose as a matrix for nucleic acid purification
Department of Pediatrics; New England Newborn Screening Program
Genetics and Genomics | Medical Genetics | Pediatrics
Nucleic acid purification is an essential but tedious step in molecular biology studies, which has been made easier since the introduction of solid binding matrix. However, the application of each type of available matrix is often limited to a specific group of nucleic acids. We have discovered a matrix, secondary fibril-associated cellulose (designated as SFcellulose), that can be used as a general-purpose matrix to isolate a wide range of nucleic acids with high yield and quality.
DOI of Published Version
Anal Biochem. 1999 Feb 15;267(2):415-8. Link to article on publisher's site
Su X, Comeau AM. (1999). Cellulose as a matrix for nucleic acid purification. Genetics. https://doi.org/10.1006/abio.1998.2987. Retrieved from https://escholarship.umassmed.edu/peds_genetics/1