Tobacco smoke exposure is an independent predictor of vitamin D deficiency in US children
UMass Chan Affiliations
Division of Endocrinology, Department of PediatricsDocument Type
Journal ArticlePublication Date
2018-10-08Keywords
Smoking habitsVitamin D deficiency
Vitamin D
Smoking related disorders
Adolescents
Children
Regression analysis
Micronutrient deficiencies
Endocrinology, Diabetes, and Metabolism
Environmental Public Health
Pediatrics
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IMPORTANCE: The role of tobacco-smoke exposure on serum vitamin D concentration in US pediatric population is not known. We hypothesized that tobacco smoke exposure would increase the prevalence of vitamin D deficiency in US children. METHODS: Representative national data were accessed from the National Health and Nutrition Examination Survey (NHANES) 2009-2010 databank on 2,263 subjects of ages 3 to 17 years. Subjects were categorized into two groups based on their age: children, if <10 >years; and youth if 10 to 17 years. Descriptive and multiple logistic regression analyses were conducted to determine the effect of serum cotinine-verified tobacco smoke exposure on vitamin D status after controlling for key sociodemographic confounders. Vitamin D deficiency was defined as 25(OH)D/mL, insufficiency as 25(OH)D of 20-29.9 ng/mL, and sufficiency as 25(OH)D of ≥30 ng/mL. Tobacco smoke exposure status was defined by serum cotinine concentration as follows: unexposed and non-smoking ( RESULTS: The prevalence of second-hand smoke exposure was 42.0% (95%CI, 36.7%-47.5%); while the prevalence of active smoking among teenagers was 9.0% (95%CI, 6.2%-12.5%). Vitamin D deficiency occurred at a frequency of 15.1% in children unexposed to tobacco smoke, 20.9% in children exposed to passive tobacco smoke, and 18.0% among actively smoking youth (p CONCLUSIONS: This analysis of a nationwide database reports that tobacco smoke exposure is an independent predictor of vitamin D deficiency in US children.Source
PLoS One. 2018 Oct 8;13(10):e0205342. doi: 10.1371/journal.pone.0205342. eCollection 2018. Link to article on publisher's site
DOI
10.1371/journal.pone.0205342Permanent Link to this Item
http://hdl.handle.net/20.500.14038/43240PubMed ID
30296288Related Resources
Link to article in PubMed. Data Availability: Data are available from the University of Massachusetts Medical School’s institutional repository, eScholarship@UMMS, at https://escholarship.umassmed.edu/pediatrics_data/7/ or https://doi.org/10.13028/M2GT2H.
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Copyright: © 2018 Nwosu, Kum-Nji. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.Distribution License
http://creativecommons.org/licenses/by/4.0/ae974a485f413a2113503eed53cd6c53
10.1371/journal.pone.0205342
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Except where otherwise noted, this item's license is described as Copyright: © 2018 Nwosu, Kum-Nji. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.