UMMS Affiliation

Department of Pediatrics

Publication Date


Document Type



Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Obesity; Adolescent; Child


Endocrine System Diseases | Endocrinology, Diabetes, and Metabolism | Pediatrics


The global pandemic of obesity in children and adolescents has resulted in a new expression of diabetes mellitus designated as double diabetes. The entity encompasses the autoimmune load of Type 1 Diabetes and the metabolic load of Type 2 Diabetes. There is no consensus on the best therapeutic modality for this new expression of diabetes mellitus. Optimal therapeutic options must address the coexistence of both metabolic and autoimmune components of diabetes mellitus in the patient. There have also been calls to revise the current classification of diabetes mellitus to take into account the surging prevalence of double diabetes in children and adolescents.

Rights and Permissions

Copyright: © 2013 Nwosu BU. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

DOI of Published Version

10.4172/2167- 0390.1000e118


Nwosu BU (2013) Double Diabetes: The Evolving Treatment Paradigm in Children and Adolescents. Vitam Trace Elem 2: e118. doi:10.4172/2167- 0390.1000e118

Journal/Book/Conference Title

Vitamins and Trace Elements