UMMS Affiliation

Department of Pediatrics

Publication Date


Document Type



Liver Diseases; Diabetes Mellitus; Vitamin D Deficiency; Blood Glucose


Endocrinology, Diabetes, and Metabolism | Pediatrics


The Management of diabetes mellitus (DM) remains an enigma even though the symptoms of the disease had been described more than 3000 years ago. This is because the central therapeutic goal of DM therapy, euglycemia, is influenced by complex physiologic and pathologic processes, some of which are clearly understood, while others are less clear. Suboptimal glycemic control is a recognized risk factor for acute and chronic complications of diabetes including microvascular and macrovascular diseases. The central question for this editorial is whether mild hepatic dysfunction could impair vitamin D metabolism and secondarily lead to sub-optimal glycemic control.

Rights and Permissions

Copyright: © 2012 Nwosu BU. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

DOI of Published Version



Nwosu BU (2012) Does Hepatic Dysfunction Worsen Glucose Homeostasis by Impairing Vitamin D Metabolism? Vitamin Trace Element 1:e109. doi:10.4172/vte.1000e109. Link to article on publisher's site

Journal/Book/Conference Title

Vitamins and Trace Elements