Document Type
Journal ArticlePublication Date
2009-10-01Keywords
AgingAnimals
Bone Diseases, Endocrine
Cystic Fibrosis
Diabetes Mellitus
Disease Progression
Female
Humans
Male
Endocrinology, Diabetes, and Metabolism
Pediatrics
Metadata
Show full item recordAbstract
Dramatic changes in the life expectancy of cystic fibrosis (CF) patients are occurring, creating a cohort of aging individuals experiencing long-term complications of this chronic disease. The two most common of these complications include CF-related diabetes and CF bone disease. The clinical implications of each have become better understood, as have potential therapies. However, data obtained from the basic science studies of both diseases have not been widely recognized. In this review, we focus on the known and hypothesized pathogenesis of these two disorders. Additionally, the molecular underpinnings of CF will be explained along with the potential interactions with endocrine disease phenotypes.Source
Stalvey, M. and Flotte, T. “Endocrine Parameters of Cystic Fibrosis: Back to Basics.” Journal of Cellular Biochemistry 2009 Oct 1;108(2):353-61. DOI: 10.1002/jcb.22284DOI
10.1002/jcb.22284Permanent Link to this Item
http://hdl.handle.net/20.500.14038/43201PubMed ID
19670266Related Resources
Link to article in PubMedae974a485f413a2113503eed53cd6c53
10.1002/jcb.22284