Extraarticular synovial chondromatosis: review of epidemiology, imaging studies, microscopy and pathogenesis, with a report of an additional case in a child
Department of Pathology; Department of Orthopedics and Physical Rehabilitation
Child; Chondromatosis, Synovial; Diagnosis, Differential; Humans; Knee; Magnetic Resonance Imaging; Male; Osteochondroma
Orthopedics | Rehabilitation and Therapy
A rare benign condition of uncertain etiology and pathogenesis, Synovial Chondromatosis (SC) is most often seen intraarticularly in adults but only a handful of cases have been reported extraarticularly in children. Symptoms and physical signs consist of pain, swelling, and osteoarthritic changes related to a mass effect. Here we discuss the case of a 9-year-old boy with documented SC of the knee and critically review the Epidemiology, Clinical Presentation, Gross Anatomy and Microscopic Histopathologic Features as well as the role of Imaging Studies in Diagnosis. In addition, this paper reviews Current Pathogenetic Concepts including the infrequent but distinct possibility of malignant transformation.
DOI of Published Version
Int J Surg Pathol. 2004 Jul;12(3):273-80. Link to article on publisher's website
International journal of surgical pathology
Ko, Emily; Mortimer, Errol; and Fraire, Armando E., "Extraarticular synovial chondromatosis: review of epidemiology, imaging studies, microscopy and pathogenesis, with a report of an additional case in a child" (2004). Orthopedics and Physical Rehabilitation Publications and Presentations. 63.