Title

Paecilomyces lilacinus olecranon bursitis in an immunocompromised host: case report and review

UMMS Affiliation

Department of Orthopedics and Physical Rehabilitation; Department of Medicine, Division of Infectious Diseases and Immunology

Publication Date

2008-03-25

Document Type

Article

Subjects

Aged, 80 and over; Animals; Bursitis; Drug Resistance, Multiple, Fungal; Humans; Immunocompromised Host; Ketoconazole; Male; Mycoses; Paecilomyces

Disciplines

Orthopedics | Rehabilitation and Therapy

Abstract

Paecilomyces lilacinus is a little-known mold that causes rare cases of invasive infections in humans regardless of their immune status. We present a unique case in an immunocompromised host with olecranon bursitis because of multidrug-resistant P. lilacinus treated with systemic ketoconazole therapy and surgical debridement. Recognition of this fungus is difficult initially because of its appearance, which can be confused with that of other fungi. Once this organism has been identified, it is recommended that antifungal susceptibility testing be obtained to guide appropriate therapy. Combination of therapeutic modalities requires case-by-case assessment. Surgical debridement and removal of prosthesis may be indicated. Although P. lilacinus can be a laboratory contaminant, in our case, causation was established as the organism grew in repeated cultures, sufficient to confirm a fungal origin for his bursitis.

DOI of Published Version

10.1016/j.diagmicrobio.2008.02.003

Source

Diagn Microbiol Infect Dis. 2008 Jul;61(3):354-7. Epub 2008 Mar 20. Link to article on publisher's site

Journal/Book/Conference Title

Diagnostic microbiology and infectious disease

Related Resources

Link to Article in PubMed

PubMed ID

18358663

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