Title

Neuromuscular dysfunction in the cancer patient: Evaluation and treatment

UMMS Affiliation

Department of Orthopedics and Physical Rehabilitation; Department of Orthopedics and Physical Rehabilitation, Division of Orthopedic Oncology

Publication Date

2018-09-01

Document Type

Article

Disciplines

Musculoskeletal Diseases | Neoplasms | Nervous System Diseases | Orthopedics | Rehabilitation and Therapy

Abstract

Cancer is a common diagnosis. In conjunction with various anti-neoplastic therapies delivered sequentially or concurrently, it makes oncology patients among the most complex to treat. This review uses a series of case studies to discuss the diagnosis and treatment of cancer-related nerve and muscle disorders. Oncologic treatment interventions such as surgery, chemotherapy, radiation therapy, and hormonal therapy, often have predictable side-effects, and sometimes their associated disability can be mitigated, especially if recognized early. Disease progression can mimic other diagnoses. The case studies provide a lens through which to study the presenting symptoms, differential diagnoses, diagnostic evaluation, and treatment interventions. These are all considered within the context of the patient's prognosis and health-related quality of life.

Keywords

muscle weakness, neoplasms, peripheral nervous system diseases, radiation, rehabilitation

DOI of Published Version

10.1002/mus.26103

Source

Muscle Nerve. 2018 Sep;58(3):335-343. doi: 10.1002/mus.26103. Epub 2018 Mar 25. Link to article on publisher's site

Journal/Book/Conference Title

Muscle and nerve

Related Resources

Link to Article in PubMed

PubMed ID

29461633

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