UMMS Affiliation

Department of Quantitative Health Sciences, Division of Preventive and Behavioral Medicine; Department of Orthopedics and Physical Rehabilitation

Publication Date


Document Type

Article Postprint


Musculoskeletal Diseases | Orthopedics | Rehabilitation and Therapy


OBJECTIVE: Although total knee replacement surgery (TKR) is highly prevalent and generally successful, functional outcomes post-TKR vary widely. Most patients receive some physical therapy (PT) following TKR, but PT practice is variable and associations between specific content and dosage of PT interventions and functional outcomes are unknown. Research has identified exercise interventions associated with better outcomes but studies have not assessed whether such evidence has been translated into clinical practice. We characterized the content, dosage and progression of usual post-acute PT services following TKR, and examined associations of specific details of post-acute PT with patients' 6-month functional outcomes.

METHODS: Post-acute PT data were collected from patients undergoing primary unilateral TKR and participating in a clinical trial of a phone-based coaching intervention. PT records from the terminal episode of care were reviewed and utilization and exercise content data were extracted. Descriptive statistics and linear regression models characterized PT treatment factors and identified associations with 6-month outcomes.

RESULTS: We analyzed 112 records from 30 PT sites. Content and dosage of specific exercises and incidence of progression varied widely. Open chain exercises were utilized more frequently than closed chain (median and interquartile range (21(4,49) vs 13(4,28.5)). Median (interquartile range) occurrence of progression of closed and open chain exercise was 0 (0,2) and 1 (0,3) respectively. Shorter timed stair climb was associated with greater total number of PT interventions and use and progression of closed chain exercises.

DISCUSSION: Data suggest that evidence-based interventions are under-utilized and dosage may be insufficient to obtain optimal outcomes.


Total Knee Replacement, outcomes, physical therapy

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This is the peer-reviewed version of the following article: Arthritis Care and Research. 2018 Oct 3. doi: 10.1002/acr.23761, which has been published in final form at This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions. Authors' accepted peer-reviewed manuscript posted after 12 months as allowed by the publisher's author rights policy at

DOI of Published Version



Arthritis Care Res (Hoboken). 2018 Oct 3. doi: 10.1002/acr.23761. [Epub ahead of print] Link to article on publisher's website

Journal/Book/Conference Title

Arthritis Care and Research

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