A longitudinal study of the effects of free testosterone and other psychosocial variables on sexual function during the natural traverse of menopause
Department of Obstetrics and Gynecology
Attitude to Health; Exercise; Female; Humans; Life Style; Longitudinal Studies; Menopause; Middle Aged; Patient Satisfaction; Prospective Studies; Psychology; Quality of Life; Questionnaires; Sexuality; Testosterone
Obstetrics and Gynecology
OBJECTIVE: This study examines the effect of free T levels on sexual function during the natural traverse of menopause. Other psychosocial variables, which may also contribute to change in sexual function, are studied-including participant's job satisfaction, satisfaction with financial resources, confidence in ability to manage symptoms, stressful life events, exercise, body image, and quality of personal relationships.
DESIGN: Prospective clinical study.
SETTING: Clinical research center, university hospital.
PATIENT(S): Fifty-seven women between the ages of 45 and 55 years were enrolled at the beginning of the study. Thirty-seven women completed all but the final measurement of free T and 23 completed all aspects of the study at year 1 and year 5.
INTERVENTION(S): Questionnaires were administered and blood samples obtained in year 1 and year 5.
MAIN OUTCOME MEASURE(S): Free T, sexual satisfaction, and other psychosocial variables.
RESULT(S): Exercise is the only variable significantly associated with sexual satisfaction. There was a lack of association between free T and sexual satisfaction both at year 1 and year 5.
CONCLUSION(S): Focus on the hormonal aspects of menopause has promoted a disregard of other important psychosocial factors affecting sexual function. This study shows no correlation between T levels and sexual function, whereas exercise is clearly associated with sexual satisfaction. A key area for future research is the effect of lifestyle changes on sexual function in menopausal women.
DOI of Published Version
Fertil Steril. 2005 Mar;83(3):643-8. Link to article on publisher's site
Fertility and sterility
Gerber JR, Johnson JV, Bunn JY, O'Brien SL. (2005). A longitudinal study of the effects of free testosterone and other psychosocial variables on sexual function during the natural traverse of menopause. Obstetrics and Gynecology Publications. https://doi.org/10.1016/j.fertnstert.2004.08.028. Retrieved from https://escholarship.umassmed.edu/obgyn_pp/68