Neuropathic uterine pain after hysterectomy. A case report

UMMS Affiliation

Department of Obstetrics and Gynecology

Publication Date


Document Type



Abscess; Adult; Amitriptyline; Analgesics, Non-Narcotic; Endometriosis; Fallopian Tube Diseases; Female; Humans; Hysterectomy; Neuralgia; Ovarian Diseases; Postoperative Complications; Treatment Outcome


Obstetrics and Gynecology


BACKGROUND: Neuropathic pain arises when there is damage to or dysfunction of the nervous system. Diabetic neuropathy, postherpetic neuralgia and phantom limb pain are common types of neuropathic pain. It is not commonly recognized in gynecologic practice.

CASE: A patient underwent a hysterectomy for a tuboovarian abscess and underlying endometriosis. Despite maximal dosing with conventional pain medications, she continued to have significant pain that had not been present following prior surgeries. Use of low-dose amitriptyline successfully treated the pain, with no sequelae.

CONCLUSION: Persistent pain following gynecologic surgery that does not respond to conventional therapy may have a neuropathic origin. Attention to appropriate history and physical examination may lead to an increase in the diagnosis of neuropathic pain in gynecology patients. This may have implications for persistent pain in other gynecologic diseases.


J Reprod Med. 2003 Jun;48(6):466-8.

Journal/Book/Conference Title

The Journal of reproductive medicine

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Link to Article in PubMed

PubMed ID