Open Access is free, unrestricted, online access to scientific and scholarly research. This collection includes Open Access journal articles authored by researchers, faculty, staff, and students of the University of Massachusetts Medical School.

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Publications from 2018

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Effects of reproductive period duration and number of pregnancies on midlife ECG indices: a secondary analysis from the Women's Health Initiative Clinical Trial, Nisha I. Parikh, Kristopher Kapphahn, Haley Hedlin, Jeffrey E. Olgin, Matthew A. Allison, Jared W. Magnani, Kelli R. Ryckman, Molly E. Waring, Marco Valentin Perez, and Barbara V. Howard

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Use of structural equation models to predict dengue illness phenotype, Sangshin Park, Anon Srikiatkhachorn, Siripen Kalayanarooj, Louis Macareo, Sharone Green, Jennifer F. Friedman, and Alan L. Rothman

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Differential expression of zinc transporters accompanies the differentiation of C2C12 myoblasts, Amanda L. Paskavitz, Julia Quintana, Daniella Cangussu, Cristina Tavera-Montanez, Yao Xiao, Sonia Ortiz-Mirnada, Juan G. Navea, and Teresita Padilla-Benavides

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Opposing Roles of FANCJ and HLTF Protect Forks and Restrain Replication during Stress, Min Peng, Ke Cong, Nicholas J. Panzarino, Sumeet Nayak, Jennifer Calvo, Bin Deng, Lihua Julie Zhu, Monika Morocz, Lili Hegedus, Lajos Haracska, and Sharon B. Cantor

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The LRRK2 Variant E193K Prevents Mitochondrial Fission Upon MPP+ Treatment by Altering LRRK2 Binding to DRP1, Maria Perez Carrion, John E. Landers, Stefano Goldwurm, and Giovanni Piccoli

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Aerobic Glycolysis Is Essential for Normal Rod Function and Controls Secondary Cone Death in Retinitis Pigmentosa, Lolita Petit, Shan Ma, Joris Cipi, Shun-Yun Cheng, Marina Zieger, Nissim Hay, and Claudio Punzo

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Widespread presentation and spontaneous regression of porokeratotic eccrine ostial and dermal duct nevus, Stephanie Petkiewicz, Julia Baltz, Kristine M. Cornejo, April C. Deng, and Karen Wiss

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Neurexin directs partner-specific synaptic connectivity in C. elegans, Alison Philbrook, Shankar Ramachandran, Christopher M. Lambert, Devyn Oliver, Jeremy Florman, Mark J. Alkema, Michele Lemons, and Michael M. Francis

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Dynamics of human protein kinase Aurora A linked to drug selectivity, Warintra Pitsawong, Vanessa Buosi, Renee Otten, Roman V. Agafonov, Adelajda Zorba, Nadja Kern, Steffen Kutter, Gunther Kern, Ricardo Ap Padua, Xavier Meniche, and Dorothee Kern

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Application of area scaling analysis to identify natural killer cell and monocyte involvement in the GranToxiLux antibody dependent cell-mediated cytotoxicity assay, Justin Pollara, Chiara Orlandi, Charles Beck, R Whitney Edwards, Yi Hu, Shuying Liu, Shixia Wang, Richard A. Koup, Thomas N. Denny, Shan Lu, Georgia D. Tomaras, Anthony DeVico, George K. Lewis, and Guido Ferrari

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Effects of Age, Race, and Ethnicity on the Optic Nerve and Peripapillary Region Using Spectral-Domain OCT 3D Volume Scans, Linda Yi-Chieh Poon, Hussein Antar, Edem Tsikata, Rong Guo, Georgia Papadogeorgou, Madeline Freeman, Ziad Khoueir, Ramon Lee, Eric Shieh, Huseyin Simavli, Christian John Que, Johannes F. de Boer, and Teresa C. Chen

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Ras hyperactivation versus overexpression: Lessons from Ras dynamics in Candida albicans, Vavilala A. Pratyusha, Guiliana Soraya Victoria, Mohammad Firoz Khan, Dominic T. Haokip, Bhawna Yadav, Nibedita Pal, Subhash Chandra Sethi, Priyanka Jain, Sneh Lata Singh, Sobhan Sen, and Sneha Sudha Komath

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Development and validation of a new MRI simulation technique that can reliably estimate optimal in vivo scanning parameters in a glioblastoma murine model, Andrea Protti, Kristen L. Jones, Dennis M. Bonal, Lei Qin, Letterio S. Politi, Sasha Kravets, Quang-De Nguyen, and Annick D. Van den Abbeele

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Preleukemia and Leukemia-Initiating Cell Activity in inv(16) Acute Myeloid Leukemia, John A. Pulikkan and Lucio H. Castilla

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Implementing universal Lynch syndrome screening (IMPULSS): protocol for a multi-site study to identify strategies to implement, adapt, and sustain genomic medicine programs in different organizational contexts, Alanna Kulchak Rahm and Mara M. Epstein

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Tuberculosis and lung damage: from epidemiology to pathophysiology, Shruthi Ravimohan, Hardy Kornfeld, Drew Weissman, and Gregory P. Bisson

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Using support vector machines on photoplethysmographic signals to discriminate between hypovolemia and euvolemia, Natasa Reljin, Gary Zimmer, Yelena Malyuta, Kirk Shelley, Yitzhak Mendelson, David J. Blehar, Chad E. Darling, and Ki H. Chon

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Resistant gonorrhoea: east meets west, Peter A. Rice and Xiao-Hong Su

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Drosophila Ror is a nervous system-specific co-receptor for Wnt ligands, Caroline Ripp, Julia Loth, Iveta Petrova, Karen Linnemannstons, Monique Ulepic, Lee G. Fradkin, Jasprien Noordermeer, and Andreas Wodarz

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Modulation of CaV1.3b L-type calcium channels by M1 muscarinic receptors varies with CaVbeta subunit expression, Mandy L. Roberts-Crowley and Ann R. Rittenhouse

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Comparison of prescribing practices for older adults treated by female versus male physicians: A retrospective cohort study, Paula A. Rochon and Jerry H. Gurwitz

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Epidemiological findings of major chemical attacks in the Syrian war are consistent with civilian targeting: a short report, Jose M. Rodriguez-Llanes, Debarati Guha-Sapir, Benjamin-Samuel Schluter, and Madelyn J. Hsiao-Rei Hicks

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PD-L1 is expressed on human platelets and is affected by immune checkpoint therapy, Verena Rolfes, Christian Idel, Ralph Pries, Kirstin Plotze-Martin, Jens Habermann, Timo Gemoll, Sabine Bohnet, Eicke Latz, Julika Ribbat-Idel, Bernardo S. Franklin, and Barbara Wollenberg

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Multi-ethnic genome-wide association study for atrial fibrillation, Carolina Roselli, Nada Esa, David D. McManus, Kahraman Tanriverdi, and Patrick T. Ellinor

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The Canady Helios Cold Plasma Scalpel Significantly Decreases Viability in Malignant Solid Tumor Cells in a Dose-Dependent Manner, Warren Rowe, Xiaoqian Cheng, Lawan Ly, Taisen Zhuang, Giacomo Basadonna, Barry Trink, Michael Keidar, and Jerome Canady

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Improving efficiency in neuroimaging research through application of Lean principles, Alexandra Roy, Julia Colpitts, Kara Becker, Judson A. Brewer, and Remko van Lutterveld

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A hybrid Neural Network Model for Joint Prediction of Presence and Period Assertions of Medical Events in Clinical Notes, Li Rumeng, Jagannatha Abhyuday, and Hong Yu

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On the Demographic and Selective Forces Shaping Patterns of Human Cytomegalovirus Variation within Hosts, Andrew M. Sackman, Susanne P. Pfeifer, Timothy F. Kowalik, and Jeffrey D. Jensen

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Novel candidate genes important for asthma and hypertension comorbidity revealed from associative gene networks, Olga V. Saik, Pavel S. Demenkov, Timofey V. Ivanisenko, Elena Yu. Bragina, Maxim B. Freidin, Irina A. Goncharova, Victor E. Dosenko, Olga I. Zolotareva, Ralf Hofestaedt, Inna N. Lavrik, Evgeny I. Rogaev, and Vladimir A. Ivanisenko

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Posttranslational modification of a histone-like protein regulates phenotypic resistance to isoniazid in mycobacteria, Alexandra Sakatos, Gregory H. Babunovic, Michael R. Chase, Alexander Dills, John D. Leszyk, Tracy Rosebrock, Bryan Bryson, and Sarah M. Fortune

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Immunohistochemical expression and prognostic value of PD-L1 in Extrapulmonary small cell carcinoma: a single institution experience, Mohammed Salhab, Yazan Migdady, Melanie Donahue, Yiqin Xiong, Karen A. Dresser, William Walsh, Benjamin J. Chen, and James Liebmann

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Stakeholder Engagement in Developing an Electronic Clinical Support Tool for Tobacco Prevention in Adolescent Primary Care, Ramzi G. Salloum, Ryan P. Theis, Lori Pbert, Matthew J. Gurka, Maribeth Porter, Diana Lee, Elizabeth A. Shenkman, and Lindsay A. Thompson

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Integrating mindfulness training in school health education to promote healthy behaviors in adolescents: Feasibility and preliminary effects on exercise and dietary habits, Elena Salmoirago-Blotcher, Susan Druker, Christine F. Frisard, Shira I. Dunsiger, Sybil L. Crawford, Florence Meleo-Meyer, Beth Bock, and Lori Pbert

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IMP3 Stabilization of WNT5B mRNA Facilitates TAZ Activation in Breast Cancer, Sanjoy Samanta, Santosh Guru, Ameer L. Elaimy, John J. Amante, Jianhong Ou, Jun Yu, Lihua Julie Zhu, and Arthur M. Mercurio

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Automated Diagnosis and Grading of Diabetic Retinopathy Using Optical Coherence Tomography, Harpal Singh. Sandhu, Ahmed Eltanboly, Ahmed Shalaby, Robert S. Keynton, Schlomit Schaal, and Ayman El-Baz

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Indexed Left Atrial Adipose Tissue Area Is Associated With Severity of Atrial Fibrillation and Atrial Fibrillation Recurrence Among Patients Undergoing Catheter Ablation, Saket R. Sanghai, Mayank Sardana, Barinder Hansra, Darleen M. Lessard, Seth T. Dahlberg, Gerard P. Aurigemma, Timothy P. Fitzgibbons, and David D. McManus

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Impact of Concurrent Genomic Alterations Detected by Comprehensive Genomic Sequencing on Clinical Outcomes in East-Asian Patients with EGFR-Mutated Lung Adenocarcinoma, Seijiro Sato, Stephen Lyle, Toshifumi Wakai, and Masanori Tsuchida

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A Qualitative Analysis of Patients' Perceptions of Shared Decision Making in the Emergency Department: "Let Me Know I Have a Choice", Elizabeth M. Schoenfeld, Sarah L. Goff, Gwendolyn Downs, Robert J. Wenger, Peter K. Lindenauer, and Kathleen M. Mazor

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Periostin antisense oligonucleotide suppresses bleomycin-induced formation of a lung premetastatic niche for melanoma, Takashi Semba, Eiji Sugihara, Nagisa Kamoshita, Sayaka Ueno, Keitaro Fukuda, Masafumi Yoshino, Kazumasa Takao, Kazunori Yoshikawa, Kenji Izuhara, Yoshimi Arima, Makoto Suzuki, and Hideyuki Saya

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Common and Dissociable Neural Activity After Mindfulness-Based Stress Reduction and Relaxation Response Programs, Gunes Sevinc, Britta K. Holzel, Javeria Hashmi, Jonathan Greenberg, Adrienne McCallister, Michael Treadway, Marissa L. Schneider, Jeffery A. Dusek, James F. Carmody, and Sara W. Lazar

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CRISPR-delivery particles targeting nuclear receptor-interacting protein 1 (Nrip1) in adipose cells to enhance energy expenditure, Yuefei Shen, Jessica L. Cohen, Sarah M. Nicoloro, Mark Kelly, Batuhan Yenilmez, Felipe Henriques, Emmanouela Tsagkaraki, Yvonne J. K. Edwards, Xiaodi Hu, Randall H. Friedline, Jason K. Kim, and Michael P. Czech

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A recombinant herpesviral vector containing a near-full-length SIVmac239 genome produces SIV particles and elicits immune responses to all nine SIV gene products, Young C. Shin, Georg F. Bischof, William A. Lauer, Lucas Gonzalez-Nieto, Eva G. Rakasz, Gregory M. Hendricks, David I. Watkins, Mauricio A. Martins, and Ronald C. Desrosiers

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Functional features defining the efficacy of cholesterol-conjugated, self-deliverable, chemically modified siRNAs, Taisia Shmushkovich, Kathryn R. Monopoli, Diana Homsy, Dmitriy Leyfer, Monica Betancur-Boissel, Anastasia Khvorova, and Alexey D. Wolfson

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Fever of Unknown Origin: Could It Be a Pheochromocytoma? A Case Report and Review of the Literature, Uzma Mohammad Siddiqui, Stephany Matta, Mireya Wessolossky, and Richard Haas

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Adapting a Behavioral Weight Loss Intervention for Delivery via Facebook: A Pilot Series Among Low-Income Postpartum Women, Valerie J. Silfee, Andrea Lopez-Cepero, Stephenie C. Lemon, Barbara Estabrook, Oanh Nguyen, Monica L. Wang, and Milagros C. Rosal

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An Update of Oral Health Curricula in US Family Medicine Residency Programs, Hugh Silk, Judith A. Savageau, Kate Sullivan, Gail Sawosik, and Min Wang

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Substrate sequence selectivity of APOBEC3A implicates intra-DNA interactions, Tania V. Silvas, Shurong Hou, Wazo Myint, Ellen A. Nalivaika, Mohan Somasundaran, Brian A. Kelch, Hiroshi Matsuo, Nese Kurt Yilmaz, and Celia A. Schiffer

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Membrane protein nanoparticles: the shape of things to come, Kailene S. Simon, Naomi L. Pollock, and Sarah C. Lee

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Prevalence and characteristics of sleep-disordered breathing in familial dysautonomia, Kanwaljit Singh, Jose-Alberto Palma, Horacio Kaufmann, Nataliya Tkachenko, Lucy Norcliffe-Kaufmann, Christy Spalink, Mikhail Kazachkov, and Sanjeev V. Kothare

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An evidence-based co-occurring disorder intervention in VA homeless programs: outcomes from a hybrid III trial, David A. Smelson, Matthew Chinman, Gordon Hannah, Thomas Byrne, and Sharon McCarthy

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Understanding and repurposing CRISPR-mediated alternative splicing, Jordan L. Smith, Haiwei Mou, and Wen Xue

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IL-16/miR-125a axis controls neutrophil recruitment in pristane-induced lung inflammation, Siobhan Smith, Hardy Kornfeld, and Caroline A. Jefferies

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Generation and characterization of monoclonal antibodies that recognize human and murine supervillin protein isoforms, Tara C. Smith, Richard G. Saul, Elisabeth R. Barton, and Elizabeth J. Luna

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Case Definitions for Conditions Identified by Newborn Screening Public Health Surveillance, Marci K. Sontag, Deboshree Sarkar, Anne Marie Comeau, Kathryn Hassell, Lorenzo D. Botto, Richard Parad, Susan R. Rose, Kupper A. Wintergerst, Kim Smith-Whitley, Sikha Singh, Careema Yusuf, Jelili Ojodu, Sara Copeland, and Cynthia F. Hinton

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What are the physical and psychological health effects of suicide bereavement on family members? An observational and interview mixed-methods study in Ireland, Ailbhe Spillane, Karen Matvienko-Sikar, Celine Larkin, Paul Corcoran, and Ella Arensman

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Systematic pan-cancer analysis of somatic allele frequency, Liam Spurr, Muzi Li, Nawaf Alomran, Qianqian Zhang, Paula Restrepo, Mercedeh Movassagh, Chris Trenkov, Nerissa Tunnessen, Tatiyana Apanasovich, Keith A. Crandall, Nathan Edwards, and Anelia Horvath

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Lifetime risk of atrial fibrillation according to optimal, borderline, or elevated levels of risk factors: cohort study based on longitudinal data from the Framingham Heart Study, Laila Staerk, Biqi Wang, Sarah R. Preis, Martin G. Larson, Steven A. Lubitz, Patrick T. Ellinor, David D. McManus, Darae Ko, Lu-Chen Weng, Kathryn L. Lunetta, Lars Frost, Emelia J. Benjamin, and Ludovic Trinquart

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Editorial: Nucleic Acids Research and Nucleic Acid Therapeutics, Barry L. Stoddard, Anastasia Khvorova, David R. Corey, William S. Dynan, and Keith R. Fox

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Targeted Delivery of Bioactive Molecules for Vascular Intervention and Tissue Engineering, Hannah A. Strobel, Elisabet I. Qendro, Eben Alsberg, and Marsha W. Rolle

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IL-15 supports the generation of protective lung-resident memory CD4 T cells, T. M. Strutt, K. Dhume, C. M. Finn, J. H. Hwang, Catherine Castonguay, Susan L. Swain, and K. K. McKinstry

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Serum anti-flagellin and anti-lipopolysaccharide immunoglobulins as predictors of linear growth faltering in Pakistani infants at risk for environmental enteric dysfunction, Sana Syed, Najeeha T. Iqbal, Kamran Sadiq, Jennie Z. Ma, Tauseef Akhund, Wenjun Xin, Sean R. Moore, Enju Liu, Shahida Qureshi, Kerri B. Gosselin, Andrew Gewirtz, Christopher P. Duggan, and S Asad. Ali

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Intestinal P-glycoprotein exports endocannabinoids to prevent inflammation and maintain homeostasis, Rose L. Szabady, Christopher Louissaint, Anneke Lubben, Bailu Xie, Shaun Reeksting, Christine Tuohy, Zachary Demma, Sage Foley, Christina S. Faherty, Alejandro Llanos-Chea, Andrew J. Olive, Randall J. Mrsny, and Beth A. McCormick

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Implementation of an active, clinic-based child tuberculosis contact management strategy in western Kenya, Daria Szkwarko, P. Owiti, N. Buziba, C. Bigelow, C. B. Eaton, and E. J. Carter

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Adeno-associated Virus Genome Population Sequencing Achieves Full Vector Genome Resolution and Reveals Human-Vector Chimeras, Phillip W. L. Tai, Jun Xie, Kaiyuen Fong, Matthew Seetin, Cheryl Heiner, Qin Su, Michael Weiand, Daniella Wilmot, Maria L. Zapp, and Guangping Gao

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Designing Shared Decision-Making Interventions for Dissemination and Sustainment: Can Implementation Science Help Translate Shared Decision Making Into Routine Practice, Andy S. Tan L, Kathleen M. Mazor, Daniel McDonald, Stella J. Lee, Demetria McNeal, Daniel D. Matlock, and Russell E. Glasgow

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Modulating Viscoelasticity, Stiffness, and Degradation of Synthetic Cellular Niches via Stoichiometric Tuning of Covalent versus Dynamic Noncovalent Cross-Linking, Yu Tan, Henry Huang, David C. Ayers, and Jie Song

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Use of ELISpot assay to study HBs-specific B cell responses in vaccinated and HBV infected humans, Chen Tian, Yuxin Chen, Yong Liu, Shixia Wang, Yang Li, Guiyang Wang, Juan Xia, Xiang-An Zhao, Rui Huang, Shan Lu, and Chao Wu

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Genome-wide CRISPR screens for Shiga toxins and ricin reveal Golgi proteins critical for glycosylation, Songhai Tian, Khaja Muneeruddin, Mei Yuk Choi, Liang Tao, Robiul H. Bhuiyan, Yuhsuke Ohmi, Keiko Furukawa, Koichi Furukawa, Sebastian Boland, Scott A. Shaffer, Rosalyn M. Adam, and Min Dong

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CIP2A facilitates the G1/S cell cycle transition via B-Myb in human papillomavirus 16 oncoprotein E6-expressing cells, Yonghao Tian, Hanxiang Chen, Lijun Qiao, Wenhao Zhang, Jingyi Zheng, Weiming Zhao, Jason J. Chen, and Weifang Zhang

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Magnitude and impact of multiple chronic conditions with advancing age in older adults hospitalized with acute myocardial infarction, Mayra Tisminetzky, Hoa L. Nguyen, Jerry H. Gurwitz, David D. McManus, Joel M. Gore, Sonal Singh, Jorge L. Yarzebski, and Robert J. Goldberg

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Central precocious puberty in Boston boys: A 10-year single center experience, Lisa Swartz Topor, Kimberly Bowerman, Jason T. Machan, Courtney L. Gilbert, Tairmae Kangarloo, and Natalie D. Shaw

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Inhibition of Triggering Receptor Expressed on Myeloid Cells 1 Ameliorates Inflammation and Macrophage and Neutrophil Activation in Alcoholic Liver Disease in Mice, David Tornai, Istvan Furi, Zu T. Shen, Alexander B. Sigalov, Sahin Coban, and Gyongyi Szabo

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Hyperglycemia and risk of ventricular tachycardia among patients hospitalized with acute myocardial infarction, Hoang V. Tran, Joel M. Gore, Chad E. Darling, Arlene S. Ash, Catarina I. Kiefe, and Robert J. Goldberg

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Ischemia augments alloimmune injury through IL-6-driven CD4(+) alloreactivity, Mayuko Uehara, Zhabiz Solhjou, Naima Banouni, Vivek Kasinath, Ye Xiaqun, Li Dai, Osman Yilmam, Mine Yilmaz, Takaharu Ichimura, Paolo Fiorina, Paulo N.A. Martins, Shunsuke Ohori, Indira Guleria, Omar H. Maarouf, Stefan G. Tullius, Martina M. McGrath, and Reza Abdi

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Activation of the apoptotic pathway during prolonged prometaphase blocks daughter cell proliferation, Yumi Uetake and Greenfield Sluder

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Cryptococcus neoformans Cda1 and Its Chitin Deacetylase Activity Are Required for Fungal Pathogenesis, Rajendra Upadhya, Lorina G. Baker, Woei C. Lam, Charles A. Specht, Maureen J. Donlin, and Jennifer K. Lodge

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Herpes ICP8 protein stimulates homologous recombination in human cells, Melvys Valledor, Richard S. Myers, and Paul C. Schiller

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Prevalence and management of iron overload in pyruvate kinase deficiency: report from the Pyruvate Kinase Deficiency Natural History Study, Eduard J. van Beers, Peter E. Newburger, and Rachael F. Grace

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The Role of Race and Economic Characteristics in the Presentation and Survival of Patients With Surgically Resected Non-Small Cell Lung Cancer, John M. Varlotto, Kerrie McKie, Rickie P. Voland, John C. Flickinger, Malcolm M. DeCamp, Debra Maddox, Paul Rava, Thomas J. Fitzgerald, William Walsh, Paulo Oliveira, Negar Rassaei, Jennifer Baima, and Karl Uy

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Editorial: Controversies in the Local Management of Lung Cancer, John M. Varlotto and Giulia Veronesi

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Population-based differences in the outcome and presentation of lung cancer patients based upon racial, histologic, and economic factors in all lung patients and those with metastatic disease, John M. Varlotto, Richard Voland, Kerrie McKie, John C. Flickinger, Malcolm M. DeCamp, Debra Maddox, Paul Rava, Thomas J. Fitzgerald, Geoffrey Graeber, Negar Rassaei, Paulo Oliveira, Suhail Ali, Chandra Belani, Jonathan Glanzman, Heather A. Wakelee, Manali Patel, Jennifer Baima, Jianying Zhang, and William Walsh

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Thermophilic Adaptation in Prokaryotes Is Constrained by Metabolic Costs of Proteostasis, Sergey V. Venev and Konstantin B. Zeldovich

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Ligand-activated BMP signaling inhibits cell differentiation and death to promote melanoma, Arvind Venkatesan, Rajesh Vyas, Alec Gramann, Karen A. Dresser, Sharvari Gujja, Sanchita Bhatnagar, Sagar Chhangawala, Camilla Borges Ferreira Gomes, Hualin Simon Xi, Christine G. Lian, Yariv Houvras, Yvonne J. K. Edwards, April C. Deng, Michael R. Green, and Craig J. Ceol

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YAP drives cutaneous squamous cell carcinoma formation and progression, Zoe Vincent-Mistiaen, Ahmed Elbediwy, Hannah Vanyai, Jennifer L. Cotton, Gordon Stamp, Emma Nye, Bradley Spencer-Dene, Gareth J. Thomas, Junhao Mao, and Barry Thompson

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Automating Installation of the Integrating Biology and the Bedside (i2b2) Platform, Kavishwar B. Wagholikar, Michael Mendis, Pralav Dessai, Javier Sanz, Sindy Law, Micheal Gilson, Stephan Sanders, Mahesh Vangala, Douglas S. Bell, and Shawn N. Murphy

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Enzyme promiscuity drives branched-chain fatty acid synthesis in adipose tissues, Martina Wallace, David A. Guertin, and Christian M. Metallo

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Increasing Resistance to Azithromycin in Neisseria gonorrhoeae in Eastern Chinese Cities: Resistance Mechanisms and Genetic Diversity among Isolates from Nanjing, Chuan Wan, Yang Li, Wen-Jing Le, Yu-Rong Liu, Sai Li, Bao-Xi Wang, Peter A. Rice, and Xiao-Hong Su

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Deconvolution of subcellular protrusion heterogeneity and the underlying actin regulator dynamics from live cell imaging, Chuangqi Wang, Hee June Choi, Sung-Jin Kim, Aesha Desai, Namgyu Lee, Dohoon Kim, Yongho Bae, and Kwonmoo Lee

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A Rationally Engineered Capsid Variant of AAV9 for Systemic CNS-Directed and Peripheral Tissue-Detargeted Gene Delivery in Neonates, Dan Wang, Shaoyong Li, Dominic J. Gessler, Jun Xie, Li Zhong, Jia Li, Karen Tran, Kim Van Vliet, Lingzhi Ren, Qin Su, Ran He, Jason E. Goetzmann, Terence R. Flotte, Mavis Agbandje-McKenna, and Guangping Gao

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Adeno-Associated Virus Neutralizing Antibodies in Large Animals and Their Impact on Brain Intraparenchymal Gene Transfer, Dan Wang, Li Zhong, Mengxin Li, Jia Li, Karen Tran, Lingzhi Ren, Ran He, Jun Xie, Richard P. Moser, Cara Fraser, Tim Kuchel, Miguel Sena-Esteves, Terence R. Flotte, Neil Aronin, and Guangping Gao

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Similarity of chest X-ray and thermal imaging of focal pneumonia: a randomised proof of concept study at a large urban teaching hospital, Linda T. Wang, Robert H. Cleveland, William Binder, Robert G. Zwerdling, Caterina Stamoulis, Thomas Ptak, Mindy Sherman, Kenan Haver, Pallavi Sagar, and Patricia Hibberd

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Humanized mice in studying efficacy and mechanisms of PD-1-targeted cancer immunotherapy, Minan Wang, Michael A. Brehm, and Dale L. Greiner

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Development and validation of a Weight Literacy Scale in English and Spanish, Monica L. Wang, Tariana V. Little, Christine F. Frisard, Amy Borg, Stephenie C. Lemon, and Milagros C. Rosal

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The Dynamic Roles of Mesenchymal Stem Cells in Colon Cancer, Shan Wang, Zhiguo Miao, Qiyuan Yang, Yimin Wang, and Jinzhou Zhang

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Inferring dynamic topology for decoding spatiotemporal structures in complex heterogeneous networks, Shuo Wang, Erik D. Herzog, Istvan Z. Kiss, William J. Schwartz, Guy Bloch, Michael Sebek, Daniel Granados-Fuentes, Liang Wang, and Jr-Shin Li

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Cutting Edge: The Heat Shock Protein gp96 Activates Inflammasome-Signaling Platforms in APCs, Yifei Wang, Abigail L. Sedlacek, Sudesh Pawaria, Haiyan Xu, Melanie J. Scott, and Robert J. Binder

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Fundamental limits on dynamic inference from single-cell snapshots, Caleb Weinreb, Samuel Wolock, Betsabeh K. Tusi, Merav Socolovsky, and Allon M. Klein

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Pathways to Kindergarten Readiness: The Roles of Second Step Early Learning Curriculum and Social Emotional, Executive Functioning, Preschool Academic and Task Behavior Skills, Melodie Wenz-Gross, Yeonsoo Yoo, Carole C. Upshur, and Anthony J. Gambino

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p38b and JAK-STAT signaling protect against Invertebrate iridescent virus 6 infection in Drosophila, Cara C. West and Neal S. Silverman

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RNA Polymerase II Transcription Attenuation at the Yeast DNA Repair Gene, DEF1, Involves Sen1-Dependent and Polyadenylation Site-Dependent Termination, Courtney Whalen, Christine Tuohy, Thomas Tallo, James W. Kaufman, Claire Moore, and Jason N. Kuehner