Open Access is free, unrestricted, online access to scientific and scholarly research. This collection includes Open Access journal articles authored by researchers, faculty, staff, and students of the University of Massachusetts Medical School.

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Publications from 2018

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All-in-one adeno-associated virus delivery and genome editing by Neisseria meningitidis Cas9 in vivo, Raed Ibraheim, Chun-Qing Song, Aamir Mir, Nadia Amrani, Wen Xue, and Erik J. Sontheimer

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Biochemical Analysis of Dimethyl Suberimidate-crosslinked Yeast Nucleosomes, Yuichi Ichikawa and Paul D. Kaufman

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An asymmetric centromeric nucleosome, Yuichi Ichikawa, Noriko Saitoh, and Paul D. Kaufman

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Computer design of microfluidic mixers for protein/RNA folding studies, Venkatesh Inguva, Sagar V. Kathuria, Osman Bilsel, and Blair James Perot

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Maximum blink interval is associated with tear film breakup time: A new simple, screening test for dry eye disease, Takenori Inomata, Masao Iwagami, Yoshimune Hiratsuka, Keiichi Fujimoto, Yuichi Okumura, Tina Shiang, and Akira Murakami

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The impact of Joint Commission International accreditation on time periods in the operating room: A retrospective observational study, Takenori Inomata, Ju Mizuno, Masao Iwagami, Shiori Kawasaki, Akie Shimada, Eiichi Inada, Tina Shiang, and Atsushi Amano

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FXR and TGR5 Agonists Ameliorate Liver Injury, Steatosis, and Inflammation After Binge or Prolonged Alcohol Feeding in Mice, Arvin Iracheta-Vellve, Charles D. Calenda, Jan Petrasek, Aditya Ambade, Karen Kodys, Luciano Adorini, and Gyongyi Szabo

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Breastfeeding History and Risk of Stroke Among Parous Postmenopausal Women in the Women's Health Initiative, Lisette T. Jacobson, Erinn M. Hade, Tracie C. Collins, Karen L. Margolis, Molly E. Waring, Linda V. Van Horn, Brian Silver, Maryam Sattari, Chloe E. Bird, Kim Kimminau, Karen Wambach, and Marcia L. Stefanick

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Robust multivariate nonparametric tests for detection of two-sample location shift in clinical trials, Xuejun Jiang, Xu Guo, Ning Zhang, Bo Wang, and Bo Zhang

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Protocol for the ROSE sustainment (ROSES) study, a sequential multiple assignment randomized trial to determine the minimum necessary intervention to maintain a postpartum depression prevention program in prenatal clinics serving low-income women, Jennifer E. Johnson, Shannon Wiltsey-Stirman, Alla Sikorskii, Ted Miller, Amanda King, Jennifer L. Blume, Xuan Pham, Tiffany A. Moore Simas, Ellen Poleshuck, Rebecca Weinberg, and Caron Zlotnick

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A cre-inducible DUX4 transgenic mouse model for investigating facioscapulohumeral muscular dystrophy, Takako I. Jones and Peter L. Jones

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Towards an arthritis flare-responsive drug delivery system, Nitin Joshi, Ellen M. Gravallese, Joerg Ermann, and Jeffrey M. Karp

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Sex-differences in post-discharge outcomes among patients hospitalized for atrial fibrillation, Bindu Kalesan, Amartya Kundu, Aditya Vaze, Elizabeth Pino, Allan J. Walkey, Ramachandran S. Vasan, and David D. McManus

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SUPPORT-AF: Piloting a Multi-Faceted, Electronic Medical Record-Based Intervention to Improve Prescription of Anticoagulation, Alok Kapoor, Azraa Amroze, Jessica G. Golden, Sybil L. Crawford, Kevin O'Day, Rasha Elhag, Ahmed Nagy, Steve A. Lubitz, Jane S. Saczynski, Jomol Mathew, and David D. McManus

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Prognostic role of elevated mir-24-3p in breast cancer and its association with the metastatic process, Alireza Khodadadi-Jamayran, Betul Akgol-Oksuz, Yelena Afanasyeva, Adriana Heguy, Marae Thompson, Karina Ray, Ariadna Giro-Perafita, Irma Sanchez, Xifeng Wu, Debu Tripathy, Anne Zeleniuch-Jacquotte, Aristotelis Tsirigos, and Francisco J. Esteva

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Understanding the Digital Gap Among US Adults With Disability: Cross-Sectional Analysis of the Health Information National Trends Survey 2013, Eun Ji Kim, Yiyang Yuan, Jane Liebschutz, Howard Cabral, and Lewis Kazis

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ANRIL: A lncRNA at the CDKN2A/B Locus With Roles in Cancer and Metabolic Disease, Yahui Kong, Chih-Heng Hsieh, and Laura C. Alonso

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Micro RNAs from DNA Viruses are Found Widely in Plasma in a Large Observational Human Population, Milka Koupenova-Zamor, Eric O. Mick, Heather A. Corkrey, Tianxiao Huan, Lauren Clancy, Ravi Shah, Emelia J. Benjamin, Daniel Levy, Evelyn A. Kurt-Jones, Kahraman Tanriverdi, and Jane E. Freedman

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Biology of Platelet Purinergic Receptors and Implications for Platelet Heterogeneity, Milka Koupenova-Zamor and Katya Ravid

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Effectiveness of Ledipasvir/Sofosbuvir and Predictors of Treatment Failure in Members with Hepatitis C Genotype 1 Infection: A Retrospective Cohort Study in a Medicaid Population, George Kouris, Tasmina Hydery, Bonnie C. Greenwood, Pavel Lavitas, Mylissa K. Price, Karen M. Clements, Caroline J. Alper, Kimberly J. Lenz, and Paul L. Jeffrey

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A microtubule-dynein tethering complex regulates the axonemal inner dynein f (I1), Tomohiro Kubo, Yuqing Hou, Deborah A. Cochran, George B. Witman, and Toshiyuki Oda

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Elevated levels of matrix metalloproteinases reflect severity and extent of disease in tuberculosis-diabetes co-morbidity and are predominantly reversed following standard anti-tuberculosis or metformin treatment, Nathella P. Kumar, Kadar Moideen, Vijay Viswanathan, Basavaradhya S. Shruthi, Shanmugam Sivakumar, Pradeep A. Menon, Hardy Kornfeld, and Subash Babu

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Defective cortex glia plasma membrane structure underlies light-induced epilepsy in cpes mutants, Govind Kunduri, Daniel Turner-Evans, Yutaka Konya, Yoshihiro Izumi, Kunio Nagashima, Stephen Lockett, Joost Holthuis, Takeshi Bamba, Usha Acharya, and Jairaj K. Acharya

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A Standard Nomenclature for Referencing and Authentication of Pluripotent Stem Cells, Andreas Kurtz, Stefanie Seltmann, and Kelly P. Smith

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TALE factors use two distinct functional modes to control an essential zebrafish gene expression program, Franck Ladam, William Stanney, Ian J. Donaldson, Ozge Yildiz, Nicoletta Bobola, and Charles G. Sagerstrom

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Low-energy Bluetooth for detecting real-world penetrance of bystander naloxone kits: a pilot study, Jeffrey T. Lai, Brittany Chapman, Katherine L. Boyle, Edward W. Boyer, and Peter R. Chai

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First Case of Pleural Empyema Caused by Staphylococcus simulans: Review of the Literature, Amos Lal, Jamal Akhtar, Ashfaq Ullah, and George Abraham

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ComprehENotes, an Instrument to Assess Patient Reading Comprehension of Electronic Health Record Notes: Development and Validation, John P. Lalor, Hao Wu, Li Chen, Kathleen M. Mazor, and Hong Yu

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Neural Network Interactions Modulate CRY-Dependent Photoresponses in Drosophila, Pallavi Lamba, Lauren E. Foley, and Patrick Emery

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Tumor-stroma interactions differentially alter drug sensitivity based on the origin of stromal cells, Benjamin D. Landry, Thomas Leete, Ryan Richards, Peter Cruz-Gordillo, Hannah R. Schwartz, Megan E. Honeywell, Gary Ren, Alyssa D. Schwartz, Shelly R. Peyton, and Michael J. Lee (Molecular systems biology, 2018-08-06)

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BB-Cl-Amidine as a novel therapeutic for canine and feline mammary cancer via activation of the endoplasmic reticulum stress pathway, Melissa M. Ledet, Robyn Anderson, Rebecca Harman, Aaron Muth, Paul R. Thompson, Scott A. Coonrod, and Gerlinde R. Van de Walle

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Potent Cas9 Inhibition in Bacterial and Human Cells by AcrIIC4 and AcrIIC5 Anti-CRISPR Proteins, Jooyoung Lee, Aamir Mir, Alireza Edraki, Bianca Garcia, Nadia Amrani, Hannah E. Lou, Ildar Gainetdinov, April Pawluk, Raed Ibraheim, Xin D. Gao, Pengpeng Liu, Alan R. Davidson, Karen L. Maxwell, and Erik J. Sontheimer

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Religiosity prevalence and its association with depression and anxiety symptoms among Hispanic/Latino adults, Shir Lerman, Molly Jung, Elva M. Arredondo, Janice M. Barnhart, Jianwen Cai, Sheila F. Castaneda, Martha L. Daviglus, Rebeca A. Espinoza, Aida L. Giachello, Kristine M. Molina, Krista Perreira, Hugo Salgado, Sylvia Wassertheil-Smoller, and Robert C. Kaplan

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Select gp120 V2 domain specific antibodies derived from HIV and SIV infection and vaccination inhibit gp120 binding to alpha4beta7, Sakaorat Lertjuthaporn, Shan Lu, Yang Lou, Shixia Wang, and James Arthos

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JNK regulates muscle remodeling via myostatin/SMAD inhibition, Sarah J. Lessard, Tara L. MacDonald, Prerana Pathak, Myoung Souk Han, Vernon G. Coffey, Johann Edge, Donato A. Rivas, Michael F. Hirshman, Roger J. Davis, and Laurie J. Goodyear

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Extraction of Information Related to Adverse Drug Events from Electronic Health Record Notes: Design of an End-to-End Model Based on Deep Learning, Fei Li, Weisong Liu, and Hong Yu

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Detecting Opioid-Related Aberrant Behavior using Natural Language Processing, Jesse M. Lingeman, Priscilla Wang, William Becker, and Hong Yu

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A Revisit to the Pretargeting Concept - A Target Conversion, Guozheng Liu

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cPLA2alpha-/- sympathetic neurons exhibit increased membrane excitability and loss of N-Type Ca2+ current inhibition by M1 muscarinic receptor signaling, Liwang Liu, Joseph V. Bonventre, and Ann R. Rittenhouse

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Ephrinb3 modulates hippocampal neurogenesis and the reelin signaling pathway in a pilocarpineinduced model of epilepsy, Tian-Tian Liu, Yi Li, Yi Shu, Bo Xiao, and Li Feng

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Indicators for prediction of Mycobacterium tuberculosis positivity detected with bronchoalveolar lavage fluid, Xi Liu, Xing-Fang Hou, Lei Gao, Guo-Fang Deng, Ming-Xia Zhang, Qun-Yi Deng, Tao-Sheng Ye, Qian-Ting Yang, Bo-Ping Zhou, Zhi-Hua Wen, Hai-Ying Liu, Hardy Kornfeld, and Xin-Chun Chen

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Splenic Infarction: An Under-recognized Complication of Infectious Mononucleosis?, Yan Li, Ann George, Sami Arnaout, Jennifer P. Wang, and George M. Abraham

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LLC tumor cells-derivated factors reduces adipogenesis in co-culture system, Magno Alves Lopes, Felipe Oliveira Franco, Felipe Henriques, Sidney Barnabe Peres, and Miguel Luiz Batista Jr.

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Dynamic Balance Measurement and Quantitative Assessment Using Wearable Plantar-Pressure Insoles in a Pose-Sensed Virtual Environment, Cunguang Lou, Chenyao Pang, Congrui Jing, Shuo Wang, Xufeng He, Xiaoguang Liu, Lei Huang, Feng Lin, Xiuling Liu, and Hongrui Wang

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Reduced gut microbiome protects from alcohol-induced neuroinflammation and alters intestinal and brain inflammasome expression, Patrick P. Lowe, Benedek Gyongyosi, Abhishek Satishchandran, Arvin Iracheta-Vellve, Yeonhee Cho, Aditya Ambade, and Gyongyi Szabo

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Insurance Coverage Policies for Pharmacogenomic and Multi-Gene Testing for Cancer, Christine Y. Lu, Stephanie Loomer, Rachel Ceccarelli, Kathleen M. Mazor, James Sabin, Ellen Wright Clayton, Geoffrey S. Ginsburg, and Ann Chen Wu

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Transcriptome Profiling of Neovascularized Corneas Reveals miR-204 as a Multi-target Biotherapy Deliverable by rAAVs, Yi Lu, Phillip W. L. Tai, Jianzhong Ai, Dominic J. Gessler, Qin Su, Xieyi Yao, Qiang Zheng, Phillip D. Zamore, Xun Xu, and Guangping Gao

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Naltrexone and Bupropion Combination Treatment for Smoking Cessation and Weight Loss in Patients With Schizophrenia, Xuechan Lyu, Jiang Du, Guilai Zhan, Yujie Wu, Hang Su, Youwei Zhu, Fredrik Jarskog, Min Zhao, and Xiaoduo Fan

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Crystal structure of the catalytic domain of HIV-1 restriction factor APOBEC3G in complex with ssDNA, Atanu Maiti, Wazo Myint, Tapan Kanai, Krista Delviks-Frankenberry, Christina Sierra Rodriguez, Vinay K. Pathak, Celia A. Schiffer, and Hiroshi Matsuo

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Randomized controlled trial of individualized treatment summary and survivorship care plans for hematopoietic cell transplantation survivors, Navneet S. Majhail and Jan Cerny

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Efficacy and safety of direct oral anticoagulants approved for cardiovascular indications: Systematic review and meta-analysis, Raghavendra Charan Makam, David C. Hoaglin, David D. McManus, Victoria Wang, Joel M. Gore, Frederick A. Spencer, Richeek Pradhan, Hoang Tran, Hong Yu, and Robert J. Goldberg

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Contemporary surgical management of thoracic empyema, Tony Makdisi and George Makdisi

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Bexarotene-Induced Hypertriglyceridemia: A Case Report, Chris Maminakis, Arin C. Whitman, and Nahida Islam

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Angiomotins stimulate LATS kinase autophosphorylation and act as scaffolds that promote Hippo signaling, Sebastian Mana-Capelli and Dannel McCollum

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Fas ligand promotes an inducible TLR-dependent model of cutaneous lupus-like inflammation, Purvi Mande, Bahar Zirak, Wei-Che Ko, Keyon Taravati, Karen L. Bride, Tia Bumpus Brodeur, April C. Deng, Karen A. Dresser, Zhaozhao Jiang, Rachel Ettinger, Katherine A. Fitzgerald, Michael D. Rosenblum, John E. Harris, and Ann Marshak-Rothstein

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Periostin and mesothelin: Potential predictors of malignant progression in intrahepatic cholangiocarcinoma, Pranoti Mandrekar and Vincenzo Cardinale

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Heat Stroke as a Cause of Liver Failure and Evaluation of Liver Transplant, Paulo N.A. Martins, Isabel M. A. Bruggenwirth, James McDaid, Martin Hertl, Tatsuo Kawai, Nahel Elias, Raymond T. Chung, and James F. Markmann

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Single-Center Experience With Liver Transplant Using Donors With Very High Transaminase Levels, Paulo N.A. Martins, Amanda Rawson, Babak Movahedi, Isabel M. A. Bruggenwirth, Natasha H. Dolgin, Ann-Britt Martins, Paria Mahboub, and Adel Bozorgzadeh

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Under one roof: identification, evaluation, and treatment of chronic hepatitis C in addiction care, Stephen A. Martin, Jordon Bosse, Amanda Wilson, Phyllis Losikoff, and Lisa Chiodo

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A parental requirement for dual-specificity phosphatase 6 in zebrafish, Jennifer M. Maurer and Charles G. Sagerstrom

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Extending chemical perturbations of the ubiquitin fitness landscape in a classroom setting reveals new constraints on sequence tolerance, David Mavor, Daniel N. Bolon, Martin Kampmann, and James S. Fraser

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RNA binding proteins co-localize with small tau inclusions in tauopathy, Brandon F. Maziuk, Daniel J. Apicco, Anna Lourdes Cruz, Lulu Jiang, Peter E. A. Ash, Edroaldo Lummertz. da Rocha, Cheng Zhang, Wai Haung Yu, John D. Leszyk, Jose F. Abisambra, Hu Li, and Benjamin Wolozin

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Intron-containing RNA from the HIV-1 provirus activates type I interferon and inflammatory cytokines, Sean M. McCauley, Kyusik Kim, Anetta Nowosielska, Ann Dauphin, Leonid Yurkovetskiy, William E. Diehl, and Jeremy Luban

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Deaf and Hard-of-Hearing Learners in Emergency Medicine, Lisa M. Meeks, Alina Engelman, Alicia Booth, and Michael Argenyi

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Primary Cardiac Lymphoma: Importance of Tissue Diagnosis, Lauren Mendelson, Emily Hsu, Hojune Chung, and Andrew Hsu

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Identification of a Novel Invasion-Promoting Region in Insulin Receptor Substrate 2, Jose Mercado-Matos, Jenny Janusis, Sha Zhu, Samuel S. Chen, and Leslie M. Shaw

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Facilitating HIV/AIDS and HIV testing literacy for emergency department patients: a randomized, controlled, trial, Roland C. Merchant, Tao Liu, Melissa A. Clark, and Michael P. Carey

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Code Help: Can This Unique State Regulatory Intervention Improve Emergency Department Crowding?, Sean S. Michael, John Broach, Kevin A. Kotkowski, David Eric Brush, Gregory A. Volturo, and Martin A. Reznek

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Heavily and fully modified RNAs guide efficient SpyCas9-mediated genome editing, Aamir Mir, Julia F. Alterman, Matthew R. Hassler, Alexandre J. Debacker, Edward Hudgens, Dimas Echeverria, Michael H. Brodsky, Anastasia Khvorova, Jonathan K. Watts, and Erik J. Sontheimer

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Extracellular vesicles in oral squamous carcinoma carry oncogenic miRNA profile and reprogram monocytes via NF-kappaB pathway, Fatemeh Momen-Heravi and Shashi Bala

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JIP1-Mediated JNK Activation Negatively Regulates Synaptic Plasticity and Spatial Memory, Caroline Morel, Tessi Sherrin, Norman J. Kennedy, Kelly H. Forest, Seda Barutcu, Michael Robles, Ezekiel Carpenter-Hyland, Naghum Alfulaij, Claire L. Standen, Robert A. Nichols, Morris Benveniste, Roger J. Davis, and Cedomir Todorovic

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The Three-Fold Axis of the HIV-1 Capsid Lattice Is the Species-Specific Binding Interface for TRIM5alpha, Damien Morger, Franziska Zosel, Martin Buhlmann, Sara Zuger, Maximilian Mittelviefhaus, Benjamin Schuler, Jeremy Luban, and Markus G. Grutter

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Donated chemical probes for open science, Susanne Muller, Paul R. Thompson, and Anke Mueller-Fahrnow

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Clinical Relation Extraction Toward Drug Safety Surveillance Using Electronic Health Record Narratives: Classical Learning Versus Deep Learning, Tsendsuren Munkhdalai, Feifan Liu, and Hong Yu

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ORBIT: a New Paradigm for Genetic Engineering of Mycobacterial Chromosomes, Kenan C. Murphy, Samantha J. Nelson, Subhalaxmi Nambi, Kadamba Papavinasasundaram, Christina E. Baer, and Christopher M. Sassetti

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MYC amplification in subtypes of breast cancers in African American women, Tammey J. Naab, Anita Gautam, Luisel Ricks-Santi, Ashwini K. Esnakula, Yasmine M. Kanaan, Robert L. DeWitty, Girmay Asgedom, Khepher H. Makambi, Massih Abawi, and Jan K. Blancato

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Morphine versus fentanyl patient-controlled analgesia for postoperative pain control in major hepatic resection surgeries including living liver donors: A retrospective study, Eman M. Nada and Abdulmajeed Alabdulkareem

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HLA-DO modulates the diversity of the MHC-II self-peptidome, Padma P. Nanaware, Mollie M. Jurewicz, John D. Leszyk, Scott A. Shaffer, and Lawrence J. Stern

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The NF-kappaB Factor Relish Regulates Atg1 Expression and Controls Autophagy, Anubhab Nandy, Lin Lin, Panagiotis D. Velentzas, Louisa P. Wu, Eric H. Baehrecke, and Neal S. Silverman

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Health Information Discrepancies Between Internet Media and Scientific Papers Reporting on Omega-3 Supplement Research: Comparative Analysis, Daryl Nault, Ariel Beccia, Haruka Ito, Sarah Kashdan, and Angela Senders

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The N-terminal region of photocleavable peptides that bind HLA-DR1 determines the kinetics of fragment release, Maria P. Negroni and Lawrence J. Stern

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Resting state functional connectivity in patients with remitted psychotic depression: A multi-centre STOP-PD study, Nicholas H. Neufeld, Benoit H. Mulsant, Erin W. Dickie, Barnett S. Meyers, George S. Alexopoulos, Anthony J. Rothschild, Ellen M. Whyte, Matthew J. Hoptman, Arash Nazeri, Jonathan Downar, Alastair J. Flint, and Aristotle N. Voineskos

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Culturally adaptive storytelling intervention versus didactic intervention to improve hypertension control in Vietnam- 12 month follow up results: A cluster randomized controlled feasibility trial, Hoa L. Nguyen, Duc A. Ha, Robert J. Goldberg, Catarina I. Kiefe, German Chiriboga, Ha N. Ly, Cuong K. Nguyen, Ngoc T. Phan, Nguyen C. Vu, Quang P. Nguyen, and Jeroan J. Allison

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Transcriptome Analysis of Neisseria gonorrhoeae during Natural Infection Reveals Differential Expression of Antibiotic Resistance Determinants between Men and Women, Kathleen Nudel, Ryan McClure, Matthew Moreau, Emma Briars, A. Jeanine Abrams, Brian Tjaden, Xiao-Hong Su, David Trees, Peter A. Rice, Paola Massari, and Caroline A. Genco

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Tobacco smoke exposure is an independent predictor of vitamin D deficiency in US children, Benjamin U. Nwosu and Philip Kum-Nji

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Children with type 1 diabetes who experienced a honeymoon phase had significantly lower LDL cholesterol 5 years after diagnosis, Benjamin U. Nwosu, Bo Zhang, Sanaa S. Ayyoub, Stephanie Choi, Tony R. Villalobos-Ortiz, Laura C. Alonso, and Bruce A. Barton

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N-terminal Sumoylation of Centromeric Histone H3 Variant Cse4 Regulates Its Proteolysis To Prevent Mislocalization to Non-centromeric Chromatin, Kentaro Ohkuni, Reuben Levy-Myers, Jack Warren, Wei-Chun Au, Yoshimitsu Takahashi, Richard E. Baker, and Munira A. Basrai

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SUMO-Targeted Ubiquitin Ligases (STUbLs) Reduce the Toxicity and Abnormal Transcriptional Activity Associated With a Mutant, Aggregation-Prone Fragment of Huntingtin, Kentaro Ohkuni, Nagesh Pasupala, Jennifer Peek, Grace Lauren Holloway, Gloria D. Sclar, Reuben Levy-Myers, Richard E. Baker, Munira A. Basrai, and Oliver Kerscher

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Red wine and green tea flavonoids are cis-allosteric activators and competitive inhibitors of GLUT1-mediated sugar uptake, Ogooluwa A. Ojelabi, Kenneth P. Lloyd, Julie K. De Zutter, and Anthony Carruthers

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Nrf2 negatively regulates STING indicating a link between antiviral sensing and metabolic reprogramming, David Olagnier, Mona Motwani, Katherine A. Fitzgerald, and Christian K. Holm

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Signaling Pathways Induced by Leptin during Epithelial(-)Mesenchymal Transition in Breast Cancer, Monserrat Olea-Flores, Juan Carlos Juarez-Cruz, Miguel A. Mendoza-Catalan, Teresita Padilla-Benavides, and Napoleon Navarro-Tito

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Tolerating the Unwelcome Guest; How the Host Withstands Persistent Mycobacterium tuberculosis, Andrew J. Olive and Christopher M. Sassetti

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Molecular Mechanisms Directing Spine Outgrowth and Synaptic Partner Selection in Caenorhabditis elegans, Devyn Oliver, Kellianne Alexander, and Michael M. Francis

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Pilot Study of Delayed ICOS/ICOS-L Blockade With alphaCD40 to Modulate Pathogenic Alloimmunity in a Primate Cardiac Allograft Model, Natalie A. O'Neill, Tianshu Zhang, Gheorghe Braileanu, Xiangfei Cheng, Alena Hershfeld, Wenji Sun, Keith A. Reimann, Sia Dahi, Natalia Kubicki, Wessam Hassanein, Christopher Laird, Arielle Cimeno, Agnes M. Azimzadeh, and Richard N. Pierson

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ATACseqQC: a Bioconductor package for post-alignment quality assessment of ATAC-seq data, Jianhong Ou, Haibo Liu, Jun Yu, Michelle A. Kelliher, Lucio H. Castilla, Nathan D. Lawson, and Lihua Julie Zhu

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Inefficient Metabolism of the Human Milk Oligosaccharides Lacto-N-tetraose and Lacto-N-neotetraose Shifts Bifidobacterium longum subsp. infantis Physiology, Ezgi Ozcan and David Sela

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Using the Habit App for Weight Loss Problem Solving: Development and Feasibility Study, Sherry Pagoto, Bengisu Tulu, Emmanuel Agu, Molly E. Waring, Jessica L. Oleski, and Danielle E. Jake-Schoffman

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Numerous recursive sites contribute to accuracy of splicing in long introns in flies, Athma A. Pai, Joseph M. Paggi, Paul Yan, Karen Adelman, and Christopher B. Burge

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A comparative analysis of preservation techniques for the optimal molecular detection of hookworm DNA in a human fecal specimen, Marina Papaiakovou, Nils Pilotte, Ben Baumer, Jessica Grant, Kristjana Asbjornsdottir, Fabian Schaer, Yan Hu, Raffi V. Aroian, Judd Walson, and Steven A. Williams

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Delayed Treatment Acceleration in Patients with Rheumatoid Arthritis Who Have Inadequate Response to Initial Tumor Necrosis Factor Inhibitors: Data from the Corrona Registry, Dimitrios A. Pappas, Robert A. Gerber, Heather J. Litman, David Gruben, Jamie Geier, Winnie D. Hua, Connie Chen, YouFu Li, Joel M. Kremer, John S. Andrews, and Jeffrey A. Bourret