Open Access is free, unrestricted, online access to scientific and scholarly research. This collection includes Open Access journal articles authored by researchers, faculty, staff, and students of the University of Massachusetts Medical School.

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Publications from 2018

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Genome-wide CRISPR screens for Shiga toxins and ricin reveal Golgi proteins critical for glycosylation, Songhai Tian, Khaja Muneeruddin, Mei Yuk Choi, Liang Tao, Robiul H. Bhuiyan, Yuhsuke Ohmi, Keiko Furukawa, Koichi Furukawa, Sebastian Boland, Scott A. Shaffer, Rosalyn M. Adam, and Min Dong

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CIP2A facilitates the G1/S cell cycle transition via B-Myb in human papillomavirus 16 oncoprotein E6-expressing cells, Yonghao Tian, Hanxiang Chen, Lijun Qiao, Wenhao Zhang, Jingyi Zheng, Weiming Zhao, Jason J. Chen, and Weifang Zhang

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Magnitude and impact of multiple chronic conditions with advancing age in older adults hospitalized with acute myocardial infarction, Mayra Tisminetzky, Hoa L. Nguyen, Jerry H. Gurwitz, David D. McManus, Joel M. Gore, Sonal Singh, Jorge L. Yarzebski, and Robert J. Goldberg

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Central precocious puberty in Boston boys: A 10-year single center experience, Lisa Swartz Topor, Kimberly Bowerman, Jason T. Machan, Courtney L. Gilbert, Tairmae Kangarloo, and Natalie D. Shaw

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Inhibition of Triggering Receptor Expressed on Myeloid Cells 1 Ameliorates Inflammation and Macrophage and Neutrophil Activation in Alcoholic Liver Disease in Mice, David Tornai, Istvan Furi, Zu T. Shen, Alexander B. Sigalov, Sahin Coban, and Gyongyi Szabo

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Hyperglycemia and risk of ventricular tachycardia among patients hospitalized with acute myocardial infarction, Hoang V. Tran, Joel M. Gore, Chad E. Darling, Arlene S. Ash, Catarina I. Kiefe, and Robert J. Goldberg

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Ischemia augments alloimmune injury through IL-6-driven CD4(+) alloreactivity, Mayuko Uehara, Zhabiz Solhjou, Naima Banouni, Vivek Kasinath, Ye Xiaqun, Li Dai, Osman Yilmam, Mine Yilmaz, Takaharu Ichimura, Paolo Fiorina, Paulo N.A. Martins, Shunsuke Ohori, Indira Guleria, Omar H. Maarouf, Stefan G. Tullius, Martina M. McGrath, and Reza Abdi

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Activation of the apoptotic pathway during prolonged prometaphase blocks daughter cell proliferation, Yumi Uetake and Greenfield Sluder

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Cryptococcus neoformans Cda1 and Its Chitin Deacetylase Activity Are Required for Fungal Pathogenesis, Rajendra Upadhya, Lorina G. Baker, Woei C. Lam, Charles A. Specht, Maureen J. Donlin, and Jennifer K. Lodge

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Herpes ICP8 protein stimulates homologous recombination in human cells, Melvys Valledor, Richard S. Myers, and Paul C. Schiller

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Prevalence and management of iron overload in pyruvate kinase deficiency: report from the Pyruvate Kinase Deficiency Natural History Study, Eduard J. van Beers, Peter E. Newburger, and Rachael F. Grace

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The Role of Race and Economic Characteristics in the Presentation and Survival of Patients With Surgically Resected Non-Small Cell Lung Cancer, John M. Varlotto, Kerrie McKie, Rickie P. Voland, John C. Flickinger, Malcolm M. DeCamp, Debra Maddox, Paul Rava, Thomas J. Fitzgerald, William Walsh, Paulo Oliveira, Negar Rassaei, Jennifer Baima, and Karl Uy

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Editorial: Controversies in the Local Management of Lung Cancer, John M. Varlotto and Giulia Veronesi

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Population-based differences in the outcome and presentation of lung cancer patients based upon racial, histologic, and economic factors in all lung patients and those with metastatic disease, John M. Varlotto, Richard Voland, Kerrie McKie, John C. Flickinger, Malcolm M. DeCamp, Debra Maddox, Paul Rava, Thomas J. Fitzgerald, Geoffrey Graeber, Negar Rassaei, Paulo Oliveira, Suhail Ali, Chandra Belani, Jonathan Glanzman, Heather A. Wakelee, Manali Patel, Jennifer Baima, Jianying Zhang, and William Walsh

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Thermophilic Adaptation in Prokaryotes Is Constrained by Metabolic Costs of Proteostasis, Sergey V. Venev and Konstantin B. Zeldovich

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Ligand-activated BMP signaling inhibits cell differentiation and death to promote melanoma, Arvind Venkatesan, Rajesh Vyas, Alec Gramann, Karen A. Dresser, Sharvari Gujja, Sanchita Bhatnagar, Sagar Chhangawala, Camilla Borges Ferreira Gomes, Hualin Simon Xi, Christine G. Lian, Yariv Houvras, Yvonne J. K. Edwards, April C. Deng, Michael R. Green, and Craig J. Ceol

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YAP drives cutaneous squamous cell carcinoma formation and progression, Zoe Vincent-Mistiaen, Ahmed Elbediwy, Hannah Vanyai, Jennifer L. Cotton, Gordon Stamp, Emma Nye, Bradley Spencer-Dene, Gareth J. Thomas, Junhao Mao, and Barry Thompson

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Automating Installation of the Integrating Biology and the Bedside (i2b2) Platform, Kavishwar B. Wagholikar, Michael Mendis, Pralav Dessai, Javier Sanz, Sindy Law, Micheal Gilson, Stephan Sanders, Mahesh Vangala, Douglas S. Bell, and Shawn N. Murphy

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Enzyme promiscuity drives branched-chain fatty acid synthesis in adipose tissues, Martina Wallace, David A. Guertin, and Christian M. Metallo

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Increasing Resistance to Azithromycin in Neisseria gonorrhoeae in Eastern Chinese Cities: Resistance Mechanisms and Genetic Diversity among Isolates from Nanjing, Chuan Wan, Yang Li, Wen-Jing Le, Yu-Rong Liu, Sai Li, Bao-Xi Wang, Peter A. Rice, and Xiao-Hong Su

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Deconvolution of subcellular protrusion heterogeneity and the underlying actin regulator dynamics from live cell imaging, Chuangqi Wang, Hee June Choi, Sung-Jin Kim, Aesha Desai, Namgyu Lee, Dohoon Kim, Yongho Bae, and Kwonmoo Lee

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A Rationally Engineered Capsid Variant of AAV9 for Systemic CNS-Directed and Peripheral Tissue-Detargeted Gene Delivery in Neonates, Dan Wang, Shaoyong Li, Dominic J. Gessler, Jun Xie, Li Zhong, Jia Li, Karen Tran, Kim Van Vliet, Lingzhi Ren, Qin Su, Ran He, Jason E. Goetzmann, Terence R. Flotte, Mavis Agbandje-McKenna, and Guangping Gao

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Adeno-Associated Virus Neutralizing Antibodies in Large Animals and Their Impact on Brain Intraparenchymal Gene Transfer, Dan Wang, Li Zhong, Mengxin Li, Jia Li, Karen Tran, Lingzhi Ren, Ran He, Jun Xie, Richard P. Moser, Cara Fraser, Tim Kuchel, Miguel Sena-Esteves, Terence R. Flotte, Neil Aronin, and Guangping Gao

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Similarity of chest X-ray and thermal imaging of focal pneumonia: a randomised proof of concept study at a large urban teaching hospital, Linda T. Wang, Robert H. Cleveland, William Binder, Robert G. Zwerdling, Caterina Stamoulis, Thomas Ptak, Mindy Sherman, Kenan Haver, Pallavi Sagar, and Patricia Hibberd

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Humanized mice in studying efficacy and mechanisms of PD-1-targeted cancer immunotherapy, Minan Wang, Michael A. Brehm, and Dale L. Greiner

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Development and validation of a Weight Literacy Scale in English and Spanish, Monica L. Wang, Tariana V. Little, Christine F. Frisard, Amy Borg, Stephenie C. Lemon, and Milagros C. Rosal

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The Dynamic Roles of Mesenchymal Stem Cells in Colon Cancer, Shan Wang, Zhiguo Miao, Qiyuan Yang, Yimin Wang, and Jinzhou Zhang

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Inferring dynamic topology for decoding spatiotemporal structures in complex heterogeneous networks, Shuo Wang, Erik D. Herzog, Istvan Z. Kiss, William J. Schwartz, Guy Bloch, Michael Sebek, Daniel Granados-Fuentes, Liang Wang, and Jr-Shin Li

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Cutting Edge: The Heat Shock Protein gp96 Activates Inflammasome-Signaling Platforms in APCs, Yifei Wang, Abigail L. Sedlacek, Sudesh Pawaria, Haiyan Xu, Melanie J. Scott, and Robert J. Binder

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Fundamental limits on dynamic inference from single-cell snapshots, Caleb Weinreb, Samuel Wolock, Betsabeh K. Tusi, Merav Socolovsky, and Allon M. Klein

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Pathways to Kindergarten Readiness: The Roles of Second Step Early Learning Curriculum and Social Emotional, Executive Functioning, Preschool Academic and Task Behavior Skills, Melodie Wenz-Gross, Yeonsoo Yoo, Carole C. Upshur, and Anthony J. Gambino

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p38b and JAK-STAT signaling protect against Invertebrate iridescent virus 6 infection in Drosophila, Cara C. West and Neal S. Silverman

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RNA Polymerase II Transcription Attenuation at the Yeast DNA Repair Gene, DEF1, Involves Sen1-Dependent and Polyadenylation Site-Dependent Termination, Courtney Whalen, Christine Tuohy, Thomas Tallo, James W. Kaufman, Claire Moore, and Jason N. Kuehner

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Protection induced by a Francisella tularensis subunit vaccine delivered by glucan particles, Adam O. Whelan, Helen C. Flick-Smith, Jane Homan, Zu T. Shen, Zoe Carpenter, Payam Khoshkenar, Ambily Abraham, Nicola J. Walker, Stuart M. Levitz, Gary R. Ostroff, and Petra C. F. Oyston

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The Implementation Process for Pharmacogenomic Testing for Cancer-Targeted Therapies, Ann Chen Wu, Kathleen M. Mazor, Rachel Ceccarelli, Stephanie Loomer, and Christine Y. Lu

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Fracture liaison services improve outcomes of patients with osteoporosis-related fractures: A systematic literature review and meta-analysis, Chih-Hsing Wu, Shih-Te Tu, Yin-Fan Chang, Ding-Cheng Chan, Jui-Teng Chien, Chih-Hsueh Lin, Sonal Singh, Manikanta Dasari, Jung-Fu Chen, and Keh-Sung Tsai

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pirScan: a webserver to predict piRNA targeting sites and to avoid transgene silencing in C. elegans, Wei-Sheng Wu, Wei-Che Huang, Jordan S. Brown, Donglei Zhang, Xiaoyan Song, Hao Chen, Shikui Tu, Zhiping Weng, and Heng-Chi Lee

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Efficient Blue to Red Afterglow Tuning in a Binary Nanocomposite Plastic Film, Yan Xia, Huase Ou, Wanbin Li, Gang Han, and Zhanjun Li

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Microtubule Acetylation Is Required for Mechanosensation in Drosophila, Connie Yan, Fei Wang, Yang Xiang, Stephen L. Rogers, and Jay Z. Parrish

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Mycobacterium tuberculosis-specific CD4+ and CD8+ T cells differ in their capacity to recognize infected macrophages, Jason D. Yang, Daniel Mott, Rujapak Sutiwisesak, Yu-Jung Lu, Fiona Raso, Britni Stowell, Greg Hunter Babunovic, Jinhee Lee, Stephen M. Carpenter, Sing Sing Way, Sarah M. Fortune, and Samuel M. Behar

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Investigation of HNF-1B as a diagnostic biomarker for pancreatic ductal adenocarcinoma, Michelle X. Yang, Ryan F. Coates, Abiy Ambaye, Juli-Anne Gardner, Richard Zubarick, Yuan Gao, Joan Skelly, James G. Liu, and Mari Mino-Kenudson

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Diabetes impairs wound healing by Dnmt1-dependent dysregulation of hematopoietic stem cells differentiation towards macrophages, Jinglian Yan, Guodong Tie, Shoying Wang, Amanda A. Tutto, Natale DeMarco, Lyne Khair, Thomas G. Fazzio, and Louis M. Messina

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Transcriptional Regulation of Lipophorin Receptors Supports Neuronal Adaptation to Chronic Elevations of Activity, Jun Yin, Mary Gibbs, Caixia Long, Justin Rosenthal, Hyong S. Kim, Anna Kim, Chengyu Sheng, Peng Ding, Uzma Javed, and Quan Yuan

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Exploiting glycan topography for computational design of Env glycoprotein antigenicity, Wen-Han Yu, Peng Zhao, Monia Draghi, Claudia Arevalo, Christina B. Karsten, Todd J. Suscovich, Bronwyn Gunn, Hendrik Streeck, Abraham L. Brass, Michael Tiemeyer, Michael Seaman, John R. Mascola, Lance Wells, Douglas A. Lauffenburger, and Galit Alter

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Colorectal cancer liver metastatic growth depends on PAD4-driven citrullination of the extracellular matrix, A. E. Yuzhalin, A. N. Gordon-Weeks, M. L. Tognoli, K. Jones, B. Markelc, R. Konietzny, R. Fischer, Aaron Muth, E. O'Neill, Paul R. Thompson, P. J. Venables, B. M. Kessler, S. Y. Lim, and R. J. Muschel

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Conserved mRNA-granule component Scd6 targets Dhh1 to repress translation initiation and activates Dcp2-mediated mRNA decay in vivo, Quira Zeidan, Feng He, Fan Zhang, Hongen Zhang, Allan Jacobson, and Alan G. Hinnebusch

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RIP kinase 1-dependent endothelial necroptosis underlies systemic inflammatory response syndrome, Matija Zelic, Justine E. Roderick, Joanne A. O'Donnell, Jesse Lehman, Sung Eun Lim, Harish P. Janardhan, Chinmay M. Trivedi, Manolis Pasparakis, and Michelle A. Kelliher

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Co-dependent Assembly of Drosophila piRNA Precursor Complexes and piRNA Cluster Heterochromatin, Gen Zhang, Shikui Tu, Tianxiong Yu, Xiao-Ou Zhang, Swapnil S. Parhad, Zhiping Weng, and William E. Theurkauf

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Gene Therapy Using a miniCEP290 Fragment Delays Photoreceptor Degeneration in a Mouse Model of Leber Congenital Amaurosis, Wei Zhang, Linjing Li, Qin Su, Guangping Gao, and Hemant Khanna

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The temporal landscape of recursive splicing during Pol II transcription elongation in human cells, Xiao-Ou Zhang, Yu Fu, Haiwei Mou, Wen Xue, and Zhiping Weng

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Substantial Increase in Compliance with Saturated Fatty Acid Intake Recommendations after One Year Following the American Heart Association Diet, Miaomiao Zhao, David E. Chiriboga, Barbara C. Olendzki, Bin Xie, Yawen Li, Lisa Jo McGonigal, Ana Maldonado-Contreras, and Yunsheng Ma

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A Web-Based Treatment Decision Support Tool for Patients With Advanced Knee Arthritis: Evaluation of User Interface and Content Design, Hua Zheng, Milagros C. Rosal, Wenjun Li, Amy Borg, Wenyun Yang, David C. Ayers, and Patricia D. Franklin

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Assessing the Readability of Medical Documents: A Ranking Approach, Jiaping Zheng and Hong Yu

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DZNep inhibits H3K27me3 deposition and delays retinal degeneration in the rd1 mice, Shijie Zheng, Lirong Xiao, Yu Liu, Yujiao Wang, Lin Cheng, Junjun Zhang, Naihong Yan, and Danian Chen

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Relationships between intensity, duration, cumulative dose, and timing of smoking with age at menopause: A pooled analysis of individual data from 17 observational studies, Dongshan Zhu, Sybil L. Crawford, and Gita D. Mishra

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Disrupted asymmetry of inter- and intra-hemispheric functional connectivity in patients with drug-naive, first-episode schizophrenia and their unaffected siblings, Furong Zhu, Feng Liu, Wenbin Guo, Jindong Chen, Qinji Su, Zhikun Zhang, Huabing Li, Xiaoduo Fan, and Jingping Zhao

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IRS2 mutations linked to invasion in pleomorphic invasive lobular carcinoma, Sha Zhu, B. Marie Ward, Jun Yu, Asia N. Matthew-Onabanjo, Jenny Janusis, Chung-Cheng Hsieh, Keith Tomaszewicz, Lloyd Hutchinson, Lihua Julie Zhu, Dina Kandil, and Leslie M. Shaw

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Transporters MRP1 and MRP2 Regulate Opposing Inflammatory Signals To Control Transepithelial Neutrophil Migration during Streptococcus pneumoniae Lung Infection, Andrew Zukauskas, Randall J. Mrsny, Paula Cortes Barrantes, Jerrold R. Turner, John M. Leong, and Beth A. McCormick

Publications from 2017

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Cannabis use is associated with reduced prevalence of non-alcoholic fatty liver disease: A cross-sectional study, Adeyinka Adejumo, Samson Alliu, Tokunbo Opeyemi Ajayi, Kelechi Lauretta Adejumo, Oluwole Muyiwa Adegbala, Nnaemeka Egbuna Onyeakusi, Akintunde Micheal Akinjero, Modupeoluwa Durojaiye, and Terence N. Bukong

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Defining the 5 and 3 landscape of the Drosophila transcriptome with Exo-seq and RNaseH-seq, Shaked Afik, Osnat Bartok, Maxim N. Artyomov, Alexander A. Shishkin, Sabah Kadri, Mor Hanan, Xiaopeng Zhu, Manuel Garber, and Sebastian Kadener

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Adeno-associated virus serotype rh.10 displays strong muscle tropism following intraperitoneal delivery, Jianzhong Ai, Jia Li, Dominic J. Gessler, Qin Su, Qiang Wei, Hong Li, and Guangping Gao

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Risks of PEG tube placement in patients with cirrhosis-associated ascites, Yasir Al-Abboodi, Ali Ridha, Matthew J. Fasullo, and Tarek H. Naguib

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Dermatologist and Patient Preferences in Choosing Treatments for Moderate to Severe Psoriasis, Matthew Alcusky, Seina Lee, Gordon Lau, Gretchen R. Chiu, Nandini Hadker, Aparna Deshpande, Stephen Fleming, Nicola Vance, and Steve Fakharzadeh

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Evaluation of the impact of a prescribing guideline on the use of intraoperative dexmedetomidine at a tertiary academic medical center, Abdullah M. Alhammad, Nour A. Baghdady, Rachel A. Mullin, and Bonnie C. Greenwood

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A High-throughput Assay for mRNA Silencing in Primary Cortical Neurons in vitro with Oligonucleotide Therapeutics, Julia F. Alterman, Andrew H. Coles, Lauren M. Hall, Neil Aronin, Anastasia Khvorova, and Marie C. Didiot

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Staying afloat in a sea of information: Point-of-care resources, Rebecca Andrews, Neil Mehta, Jack Maypole, and Stephen A. Martin

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Interpreting T-Cell Cross-reactivity through Structure: Implications for TCR-Based Cancer Immunotherapy, Dinler A. Antunes, Mauricio M. Rigo, Martiela V. Freitas, Marcus F. A. Mendes, Marialva Sinigaglia, Gregory Lizee, Lydia E. Kavraki, Liisa K. Selin, Markus Cornberg, and Gustavo F. Vieira

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FLT1 and transcriptome-wide polyadenylation site (PAS) analysis in preeclampsia, Ami Ashar-Patel, Yasin Kaymaz, Augustine Rajakumar, Jeffrey A. Bailey, S. Ananth Karumanchi, and Melissa J. Moore

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Lacunar-canalicular network in femoral cortical bone is reduced in aged women and is predominantly due to a loss of canalicular porosity, A. M. Ashique, L. S. Hart, C. D. L. Thomas, J. G. Clement, P. Pivonka, Yasmin Carter, D. D. Mousseau, and D. M. L. Cooper

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Severity of Acute Infectious Mononucleosis Correlates with Cross-Reactive Influenza CD8 T-Cell Receptor Repertoires, Nuray Aslan, Levi B. Watkin, Anna Gil, Rabinarayan Mishra, Fransenio G. Clark, Raymond M. Welsh, Dario Ghersi, Katherine Luzuriaga, and Liisa K. Selin

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Nucleosomes influence multiple steps during replication initiation, Ishara F. Azmi, Shinya Watanabe, Michael F. Maloney, Sukhyun Kang, Jason A. Belsky, David M. MacAlpine, Craig L. Peterson, and Stephen P. Bell

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A National CERA Study of the Use of Laborists in Family Medicine Residency Training, Robert A. Baldor, Christine Chang Pecci, Gerardo Moreno, Virginia Van Duyne, and Stacy E. Potts

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Local neuropeptide signaling modulates serotonergic transmission to shape the temporal organization of C. elegans egg-laying behavior, Navonil Banerjee, Raja Bhattacharya, Michael Gorczyca, Kevin M. Collins, and Michael M. Francis

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BALB/c mice immunized with a combination of virus-like particles incorporating Kaposi sarcoma-associated herpesvirus (KSHV) envelope glycoproteins gpK8.1, gB, and gH/gL induced comparable serum neutralizing antibody activity to UV-inactivated KSHV, Anne K. Barasa, Peng Ye, Meredith Phelps, Ganapathiram T. Arivudainambi, Timelia Tison, and Javier Gordon Ogembo

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Excitatory neurons sculpt GABAergic neuronal connectivity in the C. elegans motor circuit, Belinda Barbagallo, Alison Philbrook, Denis Touroutine, Navonil Banerjee, Devyn Oliver, Christopher M. Lambert, and Michael M. Francis

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Delineating CD4 dependency of HIV-1: Adaptation to infect low level CD4 expressing target cells widens cellular tropism but severely impacts on envelope functionality, David Beauparlant, Peter Rusert, Carsten Magnus, Claus Kadelka, Jacqueline Weber, Therese Uhr, Osvaldo Zagordi, Corinna Oberle, Maria J. Duenas-Decamp, Paul R. Clapham, Karin J. Metzner, Huldrych F. Gunthard, and Alexandra Trkola

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A Circulating microRNA Signature Predicts Age-Based Development of Lymphoma, Afshin Beheshti, Charles Vanderburg, J. Tyson McDonald, Charusheila Ramkumar, Tatenda Kadungure, Hong Zhang, Ronald B. Gartenhaus, and Andrew M. Evens

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HMGB1, IL-1alpha, IL-33 and S100 proteins: dual-function alarmins, Damien Bertheloot and Eicke Latz

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Functional Requirements for Heparan Sulfate Biosynthesis in Morphogenesis and Nervous System Development in C. elegans, Cassandra R. Blanchette, Andrea Thackeray, Paola N. Perrat, Siegfried Hekimi, and Claire Y. Benard

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Virtual Patient Technology: Engaging Primary Care in Quality Improvement Innovations, Amanda C. Blok, Christine N. May, Rajani S. Sadasivam, and Thomas K. Houston

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The Availability and Utility of Services to Address Risk Factors for Recidivism among Justice-Involved Veterans, Daniel M. Blonigen, Allison L. Rodriguez, Luisa Manfredi, Jessica Britt, Andrea Nevedal, Andrea K. Finlay, Joel Rosenthal, David A. Smelson, and Christine Timko

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The Trypanosome Exocyst: A Conserved Structure Revealing a New Role in Endocytosis, Cordula M. Boehm, Samson Obado, Catarina Gadelha, Alexandra Kaupisch, Paul T. Manna, Gwyn W. Gould, Mary Munson, Brian T. Chait, Michael P. Rout, and Mark C. Field

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"The Impact of Mycobacterium tuberculosis Immune Evasion on Protective Immunity: Implications for TB Vaccine Design" - Meeting report, Cesar Boggiano, Katrin Eichelberg, Lakshmi Ramachandra, Jaqueline Shea, Lalita Ramakrishnan, Samuel M. Behar, Joel D. Ernst, Steven A. Porcelli, Markus Maeurer, and Hardy Kornfeld

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Enteroaggregative Escherichia coli Adherence Fimbriae Drive Inflammatory Cell Recruitment via Interactions with Epithelial MUC1, Erik J. Boll, Jorge Ayala-Lujan, Rose L. Szabady, Christopher Louissaint, Rachel Z. Smith, Karen A. Krogfelt, James P. Nataro, Fernando Ruiz-Perez, and Beth A. McCormick

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Krill Oil-In-Water Emulsion Protects against Lipopolysaccharide-Induced Proinflammatory Activation of Macrophages In Vitro, Gabriel A. Bonaterra, David F. Driscoll, Hans Schwarzbach, and Ralf Kinscherf

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A role for Tau protein in maintaining ribosomal DNA stability and cytidine deaminase-deficient cell survival, Elias Bou Samra, Geraldine Buhagiar-Labarchede, Christelle Machon, Jerome Guitton, Rosine Onclercq-Delic, Michael R. Green, Olivier Alibert, Claude Gazin, Xavier Veaute, and Mounira Amor-Gueret

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A systems level approach to temporal expression dynamics in Drosophila reveals clusters of long term memory genes, Julianna Bozler, Balint Z. Kacsoh, Hao Chen, William E. Theurkauf, Zhiping Weng, and Giovanni Bosco

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Soluble Uric Acid Activates the NLRP3 Inflammasome, Tarcio Teodoro Braga, Maria Fernanda Forni, Matheus Correa-Costa, Rodrigo Nalio Ramos, Jose Alexandre Barbuto, Paola Branco, Angela Castoldi, Meire Ioshie Hiyane, Mariana Rodrigues Davanso, Eicke Latz, Bernardo S. Franklin, Alicia J. Kowaltowski, and Niels Olsen Saraiva Camara

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A Pilot Study of the Effects of Mindfulness-Based Stress Reduction on Post-traumatic Stress Disorder Symptoms and Brain Response to Traumatic Reminders of Combat in Operation Enduring Freedom/Operation Iraqi Freedom Combat Veterans with Post-traumatic Stress Disorder, James Douglas Bremner, Sanskriti Mishra, Carolina Campanella, Majid Shah, Nicole Kasher, Sarah Evans, Negar Fani, Amit Jasvant Shah, Collin Reiff, Lori L. Davis, Viola Vaccarino, and James F. Carmody

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Characterization of a new oda3 allele, oda3-6, defective in assembly of the outer dynein arm-docking complex in Chlamydomonas reinhardtii, Jason M. Brown, Matthew Mosley, Daniela Montes-Berrueta, Yuqing Hou, Fan Yang, Chasity Scarbrough, George B. Witman, and Maureen Wirschell

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IFT trains in different stages of assembly queue at the ciliary base for consecutive release into the cilium, Jason M. Brown, Tyler Picariello, Deborah A. Cochran, George B. Witman, and Karl Lechtreck

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Fifteen years of research on oral-facial-digital syndromes: from 1 to 16 causal genes, Ange-Line Bruel, Thibaut Eguether, Gregory J. Pazour, and Christel Thauvin-Robinet

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Donor Diabetes and Prolonged Cold Ischemia Time Synergistically Increase the Risk of Graft Failure After Liver Transplantation, Isabel M. A. Bruggenwirth, Natasha H. Dolgin, Robert J. Porte, Adel Bozorgzadeh, and Paulo N.A. Martins

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Tocilizumab combination therapy or monotherapy or methotrexate monotherapy in methotrexate-naive patients with early rheumatoid arthritis: 2-year clinical and radiographic results from the randomised, placebo-controlled FUNCTION trial, Gerd R. Burmester, William F. Rigby, Ronald F. van Vollenhoven, Jonathan Kay, Andrea Rubbert-Roth, Ricardo Blanco, Alysha Kadva, and Sophie Dimonaco

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Behavioral activation for smoking cessation and mood management following a cardiac event: results of a pilot randomized controlled trial, Andrew Busch, Erin M. Tooley, Shira Dunsiger, Elizabeth A. Chattillion, John Fani Srour, Sherry L. Pagoto, Christopher W. Kahler, and Belinda Borrelli

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Synovial fibroblast-neutrophil interactions promote pathogenic adaptive immunity in rheumatoid arthritis, Carmelo Carmona-Rivera, Paul R. Thompson, and Mariana J. Kaplan

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Vaccine-elicited memory CD4+ T cell expansion is impaired in the lungs during tuberculosis, Stephen M. Carpenter, Jason D. Yang, Jinhee Lee, Palmira Barreira-Silva, and Samuel M. Behar

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Randomized Controlled Study of a Remote Flipped Classroom Neuro-otology Curriculum, Frederick Robert Carrick, Mahera Abdulrahman, Ahmed Hankir, Maksim Zayaruzny, Kinda Najem, Palita Lungchukiet, and Roger A. Edwards

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Race, Ethnicity, Income Concentration and 10-Year Change in Urban Greenness in the United States, Joan A. Casey, Peter James, Lara Cushing, William M. Jesdale, and Rachel Morello-Frosch

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Lowering relative humidity level increases epidermal protein deimination and drives human filaggrin breakdown, Laura Cau, Valerie Pendaries, Emeline Lhuillier, Paul R. Thompson, Guy Serre, Hidenari Takahara, Marie-Claire Mechin, and Michel Simon