Open Access is free, unrestricted, online access to scientific and scholarly research. This collection includes Open Access journal articles and other materials authored by researchers, faculty, staff, and students of the University of Massachusetts Medical School.

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Publications from 2019

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A Disintegrin and Metalloproteinase 9 Domain (ADAM9) Is a Major Susceptibility Factor in the Early Stages of Encephalomyocarditis Virus Infection, Lindsey E. Bazzone, Michael King, Christopher R. MacKay, Pyae Phyo Kyawe, Paul Meraner, Daniel Lindstrom, Joselyn Rojas-Quintero, Caroline A. Owen, Jennifer P. Wang, Abraham L. Brass, Evelyn A. Kurt-Jones, and Robert W. Finberg

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A Meningococcal Outer Membrane Vesicle Vaccine with Overexpressed Mutant FHbp Elicits Higher Protective Antibody Responses in Infant Rhesus Macaques than a Licensed Serogroup B Vaccine, Peter T. Beernink, Vianca Vianzon, Lisa A. Lewis, Gregory R. Moe, and Dan M. Granoff

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Common Variants in the Glycerol Kinase Gene Reduce Tuberculosis Drug Efficacy, Michelle M. Bellerose, Seung-Hun Baek, Chuan-Chin Huang, Caitlin E. Moss, Eun-Ik Koh, Megan K. Proulx, Clare M. Smith, Richard E. Baker, Jong Seok Lee, Seokyong Eum, Sung Jae Shin, Sang-Nae Cho, Megan Murray, and Christopher M. Sassetti

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Brazilian generics market change after Farmacia Popular program, Andrea Damaso Bertoldi, Luisa Arueira Chaves, Dennis Ross-Degnan, Vera Lucia Luiza, Isabel Cristina Martins Emmerick, Rondineli Mendes da Silva, and Monica Rodrigues. Campos

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The Brazilian private pharmaceutical market after the first ten years of the generics law, Andrea Damaso Bertoldi, Anita K. Wagner, Isabel Emmerick, Luisa Arueira Chaves, Peter Stephens, and Dennis Ross-Degnan

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Using Electronic Referrals to Address Health Disparities and Improve Blood Pressure Control, Amy Bettano, Thomas Land, Alice Byrd, Susan Svencer, and Laura Nasuti

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C4BP-IgM protein as a therapeutic approach to treat Neisseria gonorrhoeae infections, Serena Bettoni, Jutamas Shaughnessy, Karolina Maziarz, David Ermert, Sunita Gulati, Bo Zheng, Matthias Morgelin, Susanne Jacobsson, Kristian Riesbeck, Magnus Unemo, Sanjay Ram, and Anna M. Blom

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Intersectional effects of racial and gender discrimination on cardiovascular health vary among black and white women and men in the CARDIA study, Ganga S. Bey, William M. Jesdale, Sarah N. Forrester, Sharina D. Person, and Catarina I. Kiefe

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A Rare Case of Extramedullary Relapse of Multiple Myeloma Causing Bowel Obstruction, Prarthna V. Bhardwaj, Shrinkhala Khanna, Majd D. Jawad, and Syed S. Ali

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Still Disease, Juhi Bhargava and Sreelakshmi Panginikkod

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Single cell transcriptomic profiling of large intestinal enteroendocrine cells in mice - Identification of selective stimuli for insulin-like peptide-5 and glucagon-like peptide-1 co-expressing cells, Lawrence J. Billing, Pierre Larraufie, Jo Lewis, Andrew B. Leiter, Joyce H. Li, Brian Lam, Giles Sh. Yeo, Deborah A. Goldspink, Richard G. Kay, Fiona M. Gribble, and Frank Reimann

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Inactivating mutations and X-ray crystal structure of the tumor suppressor OPCML reveal cancer-associated functions, James R. Birtley, Zachary Maben, Grant C. Weaver, Mollie M. Jurewicz, Lawrence J. Stern, Chiara Recchi, and Hani Gabra

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Diverse lipid conjugates for functional extra-hepatic siRNA delivery in vivo, Annabelle Biscans, Andrew H. Coles, Reka A. Haraszti, Dimas Echeverria, Matthew R. Hassler, Maire F. Osborn, and Anastasia Khvorova

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Nurse-Driven mHealth Implementation Using the Technology Inpatient Program for Smokers (TIPS): Mixed Methods Study, Amanda C. Blok, Rajani S. Sadasivam, Timothy P. Hogan, Angela Patterson, Nicole Day, and Thomas K. Houston

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Neighborhood Characteristics and Colorectal Cancer Survivors' Quality of Care, Ulrike Boehmer, Jennifer Potter, Melissa A. Clark, Al Ozonoff, Rachel M. Ceballos, Michael Winter, and Kevan L. Hartshorn

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Design and methods of the Healthy Kids and Families study: a parent-focused community health worker-delivered childhood obesity prevention intervention, Amy Borg, Christina F. Haughton, Mullen Sawyer, Stephenie C. Lemon, Kevin J. Kane, Lori Pbert, Wenjun Li, and Milagros C. Rosal

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Common Nodes of Virus-Host Interaction Revealed Through an Integrated Network Analysis, Korbinian Bosl and Richard K. Kandasamy

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Gait mechanics contribute to exercise induced pain flares in knee osteoarthritis, Katherine A. Boyer and Jocelyn F. Hafer

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Proton pump inhibitors and 180-day mortality in the elderly after Clostridium difficile treatment, Evan S. Bradley, Emily Howe, Xun Wu, and John P. Haran

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Investigating Potential Biomarkers in Autism Spectrum Disorder, Carolyn Bridgemohan, David E. Cochran, Andrew W. Zimmerman, Roula N. Choueiri, and Jean A. Frazier

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Comparison of artifacts between paste and collodion method of electrode application in pediatric EEG, Danielle Brigham, Yash Shah, Kanwaljit Singh, Ivan Pavkovic, Shefali Karkare, and Sanjeev V. Kothare

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A Persistence Detector for Metabolic Network Rewiring in an Animal, Jote T. Bulcha, Gabrielle E. Giese, Zulfikar Ali, Yong-Uk Lee, Melissa D. Walker, Amy D. Holdorf, L. Safak Yilmaz, Robert C. Brewster, and Albertha J. M. Walhout

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Clinical Molecular Marker Testing Data Capture to Promote Precision Medicine Research Within the Cancer Research Network, Andrea N. Burnett-Hartman and Mara M. Epstein

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One-year survival and admission to hospital for cardiovascular events among older residents of long-term care facilities who were prescribed intensive- and moderate-dose statins, Michael A. Campitelli, Colleen J. Maxwell, Laura C. Maclagan, Dennis T. Ko, Chaim M. Bell, Lianne Jeffs, Andrew M. Morris, Kate L. Lapane, Nick Daneman, and Susan E. Bronskill

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Diapause induces functional axonal regeneration after necrotic insult in C. elegans, Mauricio Caneo, Victoria Julian, Alexandra B. Byrne, Mark J. Alkema, and Andrea Calixto

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Preferences, use of and satisfaction with mental health services among a sample of Puerto Rican cancer patients, Eida M. Castro-Figueroa, Normarie Torres-Blasco, Milagros C. Rosal, Wallesca P. Castro, Marilis E. Gonzalez-Lorenzo, Hector Velez, Rosario Costas-Muniz, and Julio C. Jimenez

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Evaluation of prophylactic dosages of Enoxaparin in non-surgical elderly patients with renal impairment, Nibal Chamoun, Hady Ghanem, Ahmad Hachem, Essa Hariri, Christelle Lteif, Hanine Mansour, Hani Dimassi, Richard Zalloum, and Georges Ghanem

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Multi-Site Photoplethysmography Technology for Blood Pressure Assessment: Challenges and Recommendations, Gabriel Chan, Rachel Cooper, Manish Hosanee, Kaylie Welykholowa, Panayiotis A. Kyriacou, Dingchang Zheng, John Allen, Derek Abbott, Nigel H. Lovell, Richard Fletcher, and Mohamed Elgendi

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The immune checkpoint molecules PD-1, PD-L1, TIM-3 and LAG-3 in diffuse large B-cell lymphoma, Benjamin J. Chen, Ravi Dashnamoorthy, Pallavi Galera, Vladislav Makarenko, Hong Chang, Srimoyee Ghosh, and Andrew M. Evens

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Detecting Hypoglycemia Incidents Reported in Patients' Secure Messages: Using Cost-Sensitive Learning and Oversampling to Reduce Data Imbalance, Jinying Chen, John Lalor, Weisong Liu, Emily Druhl, Edgard A. Granillo, Varsha G. Vimalananda, and Hong Yu

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The Tec kinase ITK is essential for ILC2 survival and epithelial integrity in the intestine, Hyoung-Soo Cho, Andrea Reboldi, Jason A. Hall, and Leslie J. Berg

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The C. elegans heterochronic gene lin-28 coordinates the timing of hypodermal and somatic gonadal programs for hermaphrodite reproductive system morphogenesis, Sungwook Choi and Victor R. Ambros

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mHealth technologies for osteoarthritis self-management and treatment: A systematic review, Wonchan Choi, Hua Zheng, Patricia D. Franklin, and Bengisu Tulu

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Toll family members bind multiple Spatzle proteins and activate antimicrobial peptide gene expression in Drosophila, Munmun Chowdhury, Chun-Feng Li, Zhen He, Yuzhen Lu, Xu-Sheng Liu, Yu-Feng Wang, Y. Tony Ip, Michael R. Strand, and Xiao-Qiang Yu

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Role of Balloon Guide Catheter in Modern Endovascular Thrombectomy, Ju-Yu Chueh, Dong-Hun Kang, Byung Moon Kim, and Matthew J. Gounis

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Nonnative structure in a peptide model of the unfolded state of SOD1: Implications for ALS-linked aggregation, Noah R. Cohen, Jill A. Zitzewitz, Osman Bilsel, and C. Robert Matthews

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The relation between mental health problems and future violence among detained male juveniles, Olivier F. Colins and Thomas Grisso

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A Novel Tool to Improve Shared Decision Making and Adherence in Multiple Sclerosis: Development and Preliminary Testing, Nananda Col, Enrique Alvarez, Vicky Springmann, Carolina Ionete, Idanis Berrios Morales, Andrew Solomon, Christen Kutz, Carolyn Griffin, Brenda Tierman, Terrie Livingston, Michelle Patel, Danny van Leeuwen, Long Ngo, and Lori Pbert

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Mutations in the Glycosyltransferase Domain of GLT8D1 Are Associated with Familial Amyotrophic Lateral Sclerosis, Johnathan Cooper-Knock, John E. Landers, and Pamela J. Shaw

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JNK and cardiometabolic dysfunction, Siobhan M. Craige, Kai Chen, Robert M. Blanton, John F. Keaney Jr., and Shashi Kant

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Antimicrobial Resistance in Neisseria gonorrhoeae: Proceedings of the STAR Sexually Transmitted Infection-Clinical Trial Group Programmatic Meeting, Anthony D. Cristillo and Peter A. Rice

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BID-ding on necroptosis in MDS, Ben A. Croker and Michelle A. Kelliher

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Comparison of Immune Responses to Different Versions of VLP Associated Stabilized RSV Pre-Fusion F Protein, Lori M. Cullen, Madelyn R. Schmidt, Gretel M. Torres, Adam A. Capoferri, and Trudy G. Morrison

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Will savings from biosimilars offset increased costs related to dose escalation? A comparison of infliximab and golimumab for rheumatoid arthritis, Jeffrey R. Curtis, Fenglong Xie, Jonathan Kay, and Joel D. Kallich

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Harnessing robotic automation and web-based technologies to modernize scientific outreach, Orna Dahan, Bat-Shahar Dorfman, Serkan Sayin, Brittany Rosener, Tiffany Hua, Anat Yarden, and Amir Mitchell

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Control of cellular responses to mechanical cues through YAP/TAZ regulation, Ishani Dasgupta and Dannel McCollum

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Structural Organization and Dynamics of Homodimeric Cytohesin Family Arf GTPase Exchange Factors in Solution and on Membranes, Sanchaita Das, Andrew W. Malaby, Agata Nawrotek, Wenhua Zhang, Mahel Zeghouf, Sarah Maslen, Mark Skehel, Srinivas Chakravarthy, Thomas C. Irving, Osman Bilsel, Jacqueline Cherfils, and David G. Lambright

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Accelerated knee osteoarthritis is associated with pre-radiographic degeneration of the extensor mechanism and cruciate ligaments: data from the Osteoarthritis Initiative, Julie E. Davis, Matthew S. Harkey, Robert J. Ward, James W. MacKay, Bing Lu, Lori Lyn Price, Charles B. Eaton, Grace H. Lo, Mary F. Barbe, Timothy E. McAlindon, and Jeffrey B. Driban

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A Fifty-Two-Week, Randomized, Placebo-Controlled Trial of Certolizumab Pegol in Nonradiographic Axial Spondyloarthritis, Atul Deodhar, Lianne S. Gensler, Jonathan Kay, Walter P. Maksymowych, Nigil Haroon, Robert Landewe, Martin Rudwaleit, Stephen Hall, Lars Bauer, Bengt Hoepken, Natasha de Peyrecave, Brian Kilgallen, and Desiree van der Heijde

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Identification of the hyaluronic acid pathway as a therapeutic target for facioscapulohumeral muscular dystrophy, Alec M. DeSimone; John D. Leszyk; Kathryn Wagner; and Charles P. Emerson, Jr.

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Rapid Irreversible Transcriptional Reprogramming in Human Stem Cells Accompanied by Discordance between Replication Timing and Chromatin Compartment, Vishnu Dileep, Rachel Patton McCord, Job Dekker, and David M. Gilbert

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Accuracy and Usability of a Novel Algorithm for Detection of Irregular Pulse Using a Smartwatch Among Older Adults: Observational Study, Eric Y. Ding, Dong Han, Cody Whitcomb, Syed Khairul Bashar, Oluwaseun Adaramola, Apurv Soni, Jane Saczynski, Timothy P. Fitzgibbons, Majaz Moonis, Steven A. Lubitz, Darleen M. Lessard, Mellanie True Hills, Bruce A. Barton, Ki Chon, and David D. McManus

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High-fat diet in a mouse insulin-resistant model induces widespread rewiring of the phosphotyrosine signaling network, Antje Dittmann, Norman J. Kennedy, Nina L. Soltero, Nader Morshed, Miyeko D. Mana, Omer H. Yilmaz, Roger J. Davis, and Forest M. White

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Correction of pseudoexon splicing caused by a novel intronic dysferlin mutation, Janice A. Dominov, Ozgun Uyan, Diane McKenna-Yasek, Babi Ramesh Reddy Nallamilli, Virginie Kergourlay, Marc Bartoli, Nicolas Levy, Judith Hudson, Teresinha Evangelista, Hanns Lochmuller, Martin Krahn, Laura Rufibach, Madhuri Hegde, and Robert H. Brown Jr.

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Elbow Ulnar Collateral Ligament Reconstruction Using the Novel Docking Plus Technique in 324 Athletes, Benjamin F. Donohue, Marc G. Lubitz, and Timothy E. Kremchek

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The Influence of Different Fat Sources on Steatohepatitis and Fibrosis Development in the Western Diet Mouse Model of Non-alcoholic Steatohepatitis (NASH), Hannah K. Drescher, Ralf Weiskirchen, Annabelle Fulop, Carsten Hopf, Estibaliz Gonzalez de San Roman, Pitter F. Huesgen, Alain de Bruin, Laura Bongiovanni, Anette Christ, Rene Tolba, Christian Trautwein, and Daniela C. Kroy

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Comparing sensitivity to change using the 6-item versus the 17-item Hamilton depression rating scale in the GUIDED randomized controlled trial, Boadie W. Dunlop, Sagar V. Parikh, Anthony J. Rothschild, Michael E. Thase, Charles DeBattista, Charles R. Conway, Brent P. Forester, Francis M. Mondimore, Richard C. Shelton, Matthew Macaluso, Jennifer Logan, Paul Traxler, James Li, Holly Johnson, and John F. Greden

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An in-silico quality assurance study of contouring target volumes in thoracic tumors within a cooperative group setting, Hesham Elhalawani, Thomas J. Fitzgerald, Fran Laurie, Kenneth Ulin, Roy Decker, Charles R. Thomas Jr., and Clifton D. Fuller

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Differential Role of Pontomedullary Glutamatergic Neuronal Populations in Sleep-Wake Control, Evelyn T. M. Erickson, Loris L. Ferrari, Heinrich S. Gompf, and Christelle Anaclet

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A cross-sectional analysis of factors associated with detection of oncogenic human papillomavirus in human immunodeficiency virus-infected and uninfected Kenyan women, A. Ermel, P. Tonui, M. Titus, Y. Tong, N. Wong, J. Ong'echa, K. Muthoka, S. Kiptoo, Ann M. Moormann, J. Hogan, A. Mwangi, S. Cu-Uvin, P. J. Loehrer, O. Orang'o, and D. Brown

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The Molecular Basis of Human IgG-Mediated Enhancement of C4b-Binding Protein Recruitment to Group A Streptococcus, David Ermert, Maisem Laabei, Antonin Weckel, Matthias Morgelin, Martin Lundqvist, Lars Bjorck, Sanjay Ram, Sara Linse, and Anna M. Blom

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OR14I1 is a receptor for the human cytomegalovirus pentameric complex and defines viral epithelial cell tropism, Xiaofei E, Paul Meraner, Ping Lu, Jill M. Perreira, Aaron M. Aker, William M. McDougall, Ronghua Zhuge, Gary C. Chan, Rachel M. Gerstein, Patrizia Caposio, Andrew D. Yurochko, Abraham L. Brass, and Timothy F. Kowalik

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Methodology of an exercise intervention program using social incentives and gamification for obese children, Yue Fang, Yunsheng Ma, Dandan Mo, Shunxing Zhang, Mi Xiang, and Zhiruo Zhang

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GWAS for quantitative resistance phenotypes in Mycobacterium tuberculosis reveals resistance genes and regulatory regions, Maha R. Farhat, Luca Freschi, Roger Calderon, Thomas Ioerger, Matthew Snyder, Conor J. Meehan, Bouke de Jong, Leen Rigouts, Alexander Sloutsky, Devinder Kaur, Shamil Sunyaev, Dick van Soolingen, Jay Shendure, Jim Sacchettini, and Megan Murray

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Dissemination and Effectiveness of the Peer Marketing and Messaging of a Web-Assisted Tobacco Intervention: Protocol for a Hybrid Effectiveness Trial, Jamie Faro, Elizabeth Aaker Orvek, Amanda C. Blok, Catherine S. Nagawa, Annalise J. McDonald, Gregory Seward, Thomas K. Houston, Ariana Kamberi, Jeroan J. Allison, Sharina D. Person, Tina Grosowsky, and Rajani S. Sadasivam

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Proton pump inhibitors increase the severity of hepatic encephalopathy in cirrhotic patients, Matthew J. Fasullo, Prashanth Rau, Dong-Qi Liu, Erik Holzwanger, Jomol Mathew, Yurima Guilarte-Walker, and Gyongyi Szabo

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Multimodal quantitative imaging of brain cancer in cultured cells, Xin Feng, Alona Muzikansky, Alonzo H. Ross, Michael R. Hamblin, Peter R. Jermain, and Anna N. Yaroslavsky

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A data citation roadmap for scholarly data repositories, Martin Fenner, Merce Crosas, Jeffrey S. Grethe, David N. Kennedy, Henning Hermjakob, Phillippe Rocca-Serra, Gustavo Durand, Robin Berjon, Sebastian Karcher, Maryann Martone, and Tim Clark

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Advancing the implementation and sustainment of medication assisted treatment for opioid use disorders in prisons and jails, Warren J. Ferguson, Joan Johnston, Jennifer G. Clarke, Peter J. Koutoujian, Kathleen Maurer, Colleen Gallagher, Julie White, Dyana Nickl, and Faye S. Taxman

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Adipocyte ACLY Facilitates Dietary Carbohydrate Handling to Maintain Metabolic Homeostasis in Females, Sully Fernandez, John M. Viola, AnnMarie Torres, Martina Wallace, Sophie Trefely, Steven Zhao, Hayley C. Affronti, Jivani M. Gengatharan, David A. Guertin, Nathaniel W. Snyder, Christian M. Metallo, and Kathryn E. Wellen

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Outcomes and outcome measures used in evaluation of communication training in oncology - a systematic literature review, an expert workshop, and recommendations for future research, F. Fischer, S. Helmer, A. Rogge, J. I. Arraras, A. Buchholz, A. Hannawa, M. Horneber, A. Kiss, Matthias S. F. Rose, W. Sollner, B. Stein, J. Weis, P. Schofield, and C. M. Witt

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Minimal Associations Between Clinical Data and Children's Self-Reported Health-Related Quality of Life in Children With Chronic Conditions-A Cross-Sectional Study, Kathrin I. Fischer, Dana Barthel, Christiane Otto, Ulrike Ravens-Sieberer, Ute Thyen, Marcus Klein, Otto Walter, Matthias S. F. Rose, and Sandra Nolte

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Orbit image analysis machine learning software can be used for the histological quantification of acute ischemic stroke blood clots, Sean Fitzgerald, Shunli Wang, Daying Dai, Dennis H. Murphree Jr., Abhay Pandit, Andrew Douglas, Asim Rizvi, Ramanathan Kadirvel, Michael Gilvarry, Ray McCarthy, Manuel Stritt, Matthew J. Gounis, Waleed Brinjikji, David F. Kallmes, and Karen M. Doyle

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Coronary disease is not associated with robust alterations in inflammatory gene expression in human epicardial fat, Timothy P. Fitzgibbons, Nancy Lee, Khanh-Van T. Tran, Sarah M. Nicoloro, Mark Kelly, Stanley Kc Tam, and Michael P. Czech

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Positional transient loss of consciousness and hemispheric deficits in the setting of severe four-vessel extracranial cerebrovascular disease, Colleen P. Flanagan, Parth D. Sheth, and Jessica P. Simons

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Drosophila PSI controls circadian period and the phase of circadian behavior under temperature cycle via tim splicing, Lauren E. Foley, Jinli Ling, Radhika Sudhir Joshi, Naveh Evantal, Sebastian Kadener, and Patrick Emery

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Randomized trial of l-serine in patients with hereditary sensory and autonomic neuropathy type 1, Vera Fridman, Saranya Suriyanarayanan, Peter Novak, William David, Eric A. Macklin, Diane McKenna-Yasek, Kailey Walsh, Razina Aziz-Bose, Anne Louise Oaklander, Robert H. Brown Jr., Thorsten Hornemann, and Florian Eichler

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Structural organization of the C1a-e-c supercomplex within the ciliary central apparatus, Gang Fu, Lei Zhao, Erin Dymek, Yuqing Hou, Kangkang Song, Nhan Phan, Zhiguo Shang, Elizabeth F. Smith, George B. Witman, and Daniela Nicastro

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Aberrant splicing contributes to severe alpha-spectrin-linked congenital hemolytic anemia, Patrick G. Gallagher and Peter E. Newburger

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The emergence of pathogenic TNF/iNOS producing dendritic cells (Tip-DCs) in a malaria model of acute respiratory distress syndrome (ARDS) is dependent on CCR4, Bruno Galvao-Filho, Julia Teixeira de Castro, Maria Marta Figueiredo, Claudio Goncalves Rosmaninho, Lis Ribeiro do Valle Antonelli, and Ricardo T. Gazzinelli

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Protocol for serious fall injury adjudication in the Strategies to Reduce Injuries and Develop Confidence in Elders (STRIDE) study, David A. Ganz and Jerry H. Gurwitz

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Characterization and comparisons of microbiota in different intestinal segments between adult Chinese Shanxi Black Pigs and Large White Pigs, Pengfei Gao; Yulong Guo; Ningfang Zhang; Wanfeng Zhang; Hejie Wang; Xiaohong Guo; Zhibian Duan; Min Du; Qiyuan Yang; Bugao Li; Guangzhou Genedenovo Biotechnology Co., Ltd.; and Shanxi Agricultural University

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Anti-CRISPR AcrIIA5 Potently Inhibits All Cas9 Homologs Used for Genome Editing, Bianca Garcia, Jooyoung Lee, Alireza Edraki, Yurima Hidalgo-Reyes, Steven Erwood, Aamir Mir, Chantel N. Trost, Uri Seroussi, Sabrina Y. Stanley, Ronald D. Cohn, Julie M. Claycomb, Erik J. Sontheimer, Karen L. Maxwell, and Alan R. Davidson

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Effectiveness of integrative medicine group visits in chronic pain and depressive symptoms: A randomized controlled trial, Paula Gardiner, Man Luo, Salvatore D'Amico, Katherine Gergen-Barnett, Laura F. White, Robert Saper, Suzanne Mitchell, and Jane M. Liebschutz

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Anti-drug Antibody Responses Impair Prophylaxis Mediated by AAV-Delivered HIV-1 Broadly Neutralizing Antibodies, Matthew R. Gardner, Ina Fetzer, Lisa M. Kattenhorn, Meredith E. Davis-Gardner, Amber S. Zhou, Barnett Alfant, Jesse A. Weber, Hema R. Kondur, Jose M. Martinez-Navio, Sebastian P. Fuchs, Ronald C. Desrosiers, Guangping Gao, Jeffrey D. Lifson, and Michael Farzan

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The non-canonical SMC protein SmcHD1 antagonises TAD formation and compartmentalisation on the inactive X chromosome, Michal R. Gdula, Tatyana B. Nesterova, Greta Pintacuda, Jonathan Godwin, Ye Zhan, Hakan Ozadam, Michael McClellan, Daniella Moralli, Felix Krueger, Catherine M. Green, Wolf Reik, Skirmantas Kriaucionis, Edith Heard, Job Dekker, and Neil Brockdorff

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Single-Cell RNA-Sequencing-Based CRISPRi Screening Resolves Molecular Drivers of Early Human Endoderm Development, Ryan M. Genga, Eric M. Kernfeld, Krishna M. Parsi, Teagan J. Parsons, Michael J. Ziller, and Rene Maehr

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Modulation of actin polymerization affects nucleocytoplasmic transport in multiple forms of amyotrophic lateral sclerosis, Anthony Giampetruzzi, Eric W. Danielson, Valentina Gumina, Maryangel Jeon, Sivakumar Boopathy, Robert H. Brown Jr., Antonia Ratti, John E. Landers, and Claudia Fallini

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Citalopram in first episode schizophrenia: The DECIFER trial, Donald C. Goff and Xiaoduo Fan

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Comparison of bicarbonate values from venous blood gas and chemistry panels measured at the time of diagnosis and resolution of diabetes ketoacidosis, Poorani Nallam Goundan, Devina Luhur Willard, Ayse Sahin-Efe, Shu-Ling Liang Fan, and Sara Michelle Alexanian

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Comparison of a Potential Hospital Quality Metric With Existing Metrics for Surgical Quality-Associated Readmission, Laura A. Graham, Hillary J. Mull, Todd H. Wagner, Melanie S. Morris, Amy K. Rosen, Joshua S. Richman, Jeffery Whittle, Edith Burns, Laurel A. Copeland, Kamal M. F. Itani, and Mary T. Hawn

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Regulation of zebrafish melanocyte development by ligand-dependent BMP signaling, Alec Gramann, Arvind M. Venkatesan, Melissa Guerin, and Craig J. Ceol

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Impact of pharmacogenomics on clinical outcomes in major depressive disorder in the GUIDED trial: A large, patient- and rater-blinded, randomized, controlled study, John F. Greden and Anthony J. Rothschild

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Gene expression signature of atypical breast hyperplasia and regulation by SFRP1, Kelly J. Gregory, Giovanna M. Crisi, Brooke A. Bentley, Grace Makari-Judson, Holly S. Mason, Jun Yu, Lihua Julie Zhu, Karl J. Simin, Jacob P. S. Johnson, Ashraf Khan, Sallie S. Schneider, and D. Joseph Jerry

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Bridging from Intramuscular to Limb Perfusion Delivery of rAAV: Optimization in a Non-human Primate Study, Alisha Gruntman, Gwladys Gernoux, Qiushi Tang, Guo-Jie Ye, Dave R. Knop, Gensheng Wang, Janet Benson, Kristen E. Coleman, Allison M. Keeler, Christian Mueller, Louis G. Chicoine, Jeffrey D. Chulay, and Terence R. Flotte

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Perspectives of health educators and interviewers in a randomized controlled trial of a postpartum diabetes prevention program for Latinas: a qualitative assessment, Aline Gubrium, Denise Leckenby, Megan Ward Harvey, Bess H. Marcus, Milagros C. Rosal, and Lisa Chasan-Taber

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Complement alone drives efficacy of a chimeric antigonococcal monoclonal antibody, Sunita Gulati, Frank J. Beurskens, Bo Zheng, Rosane B. DeOliveira, Jutamas Shaughnessy, Nancy Nowak, Peter A. Rice, and Sanjay Ram

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Preclinical Efficacy of a Lipooligosaccharide Peptide Mimic Candidate Gonococcal Vaccine, Sunita Gulati, Michael W. Pennington, Andrzej Czerwinski, Darrick Carter, Bo Zheng, Nancy Nowak, Rosane B. DeOliveira, Jutamas Shaughnessy, George W. Reed, Sanjay Ram, and Peter A. Rice

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Targeting Lipooligosaccharide (LOS) for a Gonococcal Vaccine, Sunita Gulati, Jutamas Shaughnessy, Sanjay Ram, and Peter A. Rice

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Association Between Alcohol Use Disorders and Outcomes of Patients Hospitalized With Community-Acquired Pneumonia, Niyati M. Gupta, Peter K. Lindenauer, Pei-Chun Yu, Peter B. Imrey, Sarah Haessler, Abhishek Deshpande, Thomas L. Higgins, and Michael B. Rothberg