Open Access is free, unrestricted, online access to scientific and scholarly research. This collection includes Open Access journal articles authored by researchers, faculty, staff, and students of the University of Massachusetts Medical School.

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Publications from 2019

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Considerations of Privacy and Confidentiality in Developing a Clinical Support Tool for Adolescent Tobacco Prevention: Qualitative Study, Ryan P. Theis, Ali M. Malik, Lindsay A. Thompson, Elizabeth A. Shenkman, Lori Pbert, and Ramzi G. Salloum

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Integrative Group Medical Visits: A National Scoping Survey of Safety-Net Clinics, Ariana Thompson-Lastad, Paula Gardiner, and Maria T. Chao

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Dietary alpha-ketoglutarate promotes beige adipogenesis and prevents obesity in middle-aged mice, Qiyu Tian, Junxing Zhao, Qiyuan Yang, Bo Wang, Jeanene M. Deavila, Mei-Jun Zhu, and Min Du

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Measuring quality and outcomes of research collaborations: An integrative review, Beth B. Tigges, Doriane Miller, Katherine M. Dudding, Joyce E. Balls-Berry, Elaine A. Borawski, Gaurav Dave, Nathaniel Hafer, Kim S. Kimminau, Rhonda G. Kost, Kimberly Littlefield, Jackilen Shannon, and Usha Menon

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The RNA-binding protein FUS/TLS undergoes calcium-mediated nuclear egress during excitotoxic stress and is required for GRIA2 mRNA processing, Maeve Tischbein, Desiree M. Baron, Yen-Chen Lin, Katherine V. Gall, John E. Landers, Claudia Fallini, and Daryl A. Bosco

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Impact of cardiac- and noncardiac-related conditions on adverse outcomes in patients hospitalized with acute myocardial infarction, Mayra Tisminetzky, Jerry H. Gurwitz, Ruben Miozzo, Joel M. Gore, Darleen M. Lessard, Jorge L. Yarzebski, and Robert J. Goldberg

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Adult-onset bilateral Parry-Romberg syndrome, Elizabeth Tkachenko, Michael J. Cunningham, Patrick O'Donnell, and Nikki A. Levin

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Regional vitiligo induced by imiquimod treatment for in-transit melanoma metastases, Elizabeth Tkachenko, Jennifer Y. Lin, and Rebecca I. Hartman

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Distinct transcriptional roles for Histone H3-K56 acetylation during the cell cycle in Yeast, Salih Topal, Pauline Vasseur, Marta Radman-Livaja, and Craig L. Peterson

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Huntingtin associates with the actin cytoskeleton and alpha-actinin isoforms to influence stimulus dependent morphology changes, Adelaide Tousley, Maria Iuliano, Elizabeth Weisman, Ellen Sapp, Heather Richardson, Petr Vodicka, Jonathan Alexander, Neil Aronin, Marian DiFiglia, and Kimberly B. Kegel-Gleason

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Transplantation of Renal Allograft After Removal of Renal Cell Carcinoma: Case Report and Review of the Literature, Anthony P. Tran, Paulo N.A. Martins, Zachary G. Papazian, Vijay K. Vanguri, Babak Movahedi, Pang-Yen Fan, Kenneth A. Bodziak, Jennifer K. Yates, Mitchell H. Sokoloff, and Adel Bozorgzadeh

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Micro-RNAs Are Related to Epicardial Adipose Tissue in Participants With Atrial Fibrillation: Data From the MiRhythm Study, Khanh-Van T. Tran, Jordan Majka, Saket Sanghai, Mayank Sardana, Darleen M. Lessard, Zachary J. Milstone, Kahraman Tanriverdi, Jane E. Freedman, Timothy P. Fitzgibbons, and David D. McManus

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Circulating extracellular RNAs, myocardial remodeling, and heart failure in patients with acute coronary syndrome, Khanh-Van T. Tran, Kahraman Tanriverdi, Gerard P. Aurigemma, Darleen M. Lessard, Mayank Sardana, Matthew Parker, Amir Y. Shaikh, Matthew Gottbrecht, Zachary Milstone, Selim E. Tanriverdi, Olga Vitseva, John F. Keaney Jr., Catarina I. Kiefe, David D. McManus, and Jane E. Freedman

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Asthma in Children and Adults-What Are the Differences and What Can They Tell us About Asthma, Michelle K. Trivedi and Eve Denton

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Preserving Continuing Medical Education in a U.S. Community Hospital: A Successful Model and an Alert, Henry Tulgan

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Identification of small molecule enzyme inhibitors as broad-spectrum anthelmintics, Rahul Tyagi, Elfawal A. Mostafa, Scott A. Wildman, Jon Helander, Christina A. Bulman, Judy Sakanari, Bruce A. Rosa, Paul J. Brindley, James W. Janetka, Raffi V. Aroian, and Makedonka Mitreva

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Classification and monomer-by-monomer annotation dataset of suprachromosomal family 1 alpha satellite higher-order repeats in hg38 human genome assembly, L. I. Uralsky, V. A. Shepelev, A. A. Alexandrov, Y. B. Yurov, Evgeny I. Rogaev, and I. A. Alexandrov

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Bacterial blood stream infections (BSIs), particularly post-engraftment BSIs, are associated with increased mortality after allogeneic hematopoietic cell transplantation, Celalettin Ustun and Jan Cerny

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gMS-Classifier1 does not predict disability progression in multiple sclerosis, Johannis A. van Rossum, Joep Killestein, Luisa M. Villar, Peter N. Riskind, Mark S. Freedman, and Charlotte Teunissen

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The Pseudomonas aeruginosa accessory genome elements influence virulence towards Caenorhabditis elegans, Alejandro Vasquez-Rifo, Isana Veksler-Lublinsky, Zhenyu Cheng, Frederick M. Ausubel, and Victor R. Ambros

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AGS Report on Engagement Related to the NIH Inclusion Across the Lifespan Policy, Camille P. Vaughan, William Dale, Heather G. Allore, Ellen F. Binder, Cynthia M. Boyd, Julie P.W. Bynum, Jerry H. Gurwitz, Nancy E. Lundebjerg, Daniel E. Trucil, Mark A. Supiano, and Cathleen Colon-Emeric

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Is Left Ventricular Global Longitudinal Strain by Two-Dimensional Speckle Tracking Echocardiography in Sepsis Cardiomyopathy Ready for Prime Time Use in the ICU, Venu Madhav Velagapudi, Rahul Pidikiti, and Dennis A. Tighe

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Reassessing the Role of Histaminergic Tuberomammillary Neurons in Arousal Control, Anne Venner, Takatoshi Mochizuki, Roberto De Luca, Christelle Anaclet, Thomas E. Scammell, Clifford B. Saper, Elda Arrigoni, and Patrick M. Fuller

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Impact of Th1 CD4 TFH skewing on Antibody Responses to an HIV-1 Vaccine in Rhesus Macaques, Anil Verma, Keith A. Reimann, David H. Foehl, and Smita S. Iyer

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Ouabain Enhances Cell-Cell Adhesion Mediated by beta1 Subunits of the Na(+),K(+)-ATPase in CHO Fibroblasts, Claudia Andrea Vilchis-Nestor, Maria Luisa Roldan, Angelina Leonardi, Juan G. Navea, Teresita Padilla-Benavides, and Liora Shoshani

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Crossover recombination and synapsis are linked by adjacent regions within the N terminus of the Zip1 synaptonemal complex protein, Karen Voelkel-Meiman, Shun-Yun Cheng, Melanie Parziale, Savannah J. Morehouse, Arden Feil, Owen R. Davies, Arnaud de Muyt, Valerie Borde, and Amy J. MacQueen

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Trends in Socioeconomic Inequalities in Full Vaccination Coverage among Vietnamese Children aged 12-23 Months, 2000-2014: Evidence for Mitigating Disparities in Vaccination, Hoang-Long Vo, Le-Thai-Bao Huynh, Hao Nguyen Si Anh, Dang-An Do, Thi-Ngoc-Ha Doan, Thi-Huyen-Trang Nguyen, and Huy Nguyen Van

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Gene Delivery to Nonhuman Primate Preimplantation Embryos Using Recombinant Adeno-Associated Virus, Dan Wang, Yuyu Niu, Lingzhi Ren, Yu Kang, Phillip W. L. Tai, Chenyang Si, Craig A. Mendonca, Hong Ma, Guangping Gao, and Weizhi Ji

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Screening and identification of RhD antigen mimic epitopes from a phage display random peptide library for the serodiagnosis of haemolytic disease of the foetus and newborn, Jiao Wang, Jingjing Song, Shuimei Zhou, Yourong Fu, Jeffrey A. Bailey, and Changxin Shen

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Non-equilibrium critical dynamics of bursts in theta and delta rhythms as fundamental characteristic of sleep and wake micro-architecture, Jilin W. J. L. Wang, Fabrizio Lombardi, Xiyun Zhang, Christelle Anaclet, and Plamen Ch. Ivanov

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Reducing sugary drink intake through youth empowerment: results from a pilot-site randomized study, Monica L. Wang, Marisa Otis, Milagros C. Rosal, Christina F. Griecci, and Stephenie C. Lemon

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A note on misspecification in general linear models with correlated errors for the analysis of crossover clinical trials, Wei Wang, Ning Cong, Tian Chen, Hui Zhang, and Bo Zhang

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Characteristics Associated With Facebook Use and Interest in Digital Disease Support Among Older Adults With Atrial Fibrillation: Cross-Sectional Analysis of Baseline Data From the Systematic Assessment of Geriatric Elements in Atrial Fibrillation (SAGE-AF) Cohort, Molly E. Waring, Mellanie T. Hills, Darleen M. Lessard, Jane S. Saczynski, Brooke A. Libby, Marta M. Holovatska, Alok Kapoor, Catarina I. Kiefe, and David D. McManus

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Delivering a Post-Partum Weight Loss Intervention via Facebook or In-Person Groups: Protocol for a Randomized Feasibility Pilot Trial, Molly E. Waring, Brooke A. Libby, Tiffany A. Moore Simas, Madison L. Bracken, Jessica L. Bibeau, Valeria Herrera, Justin Wang, and Sherry L. Pagoto

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Gap Analysis Regarding Prognostication in Neurocritical Care: A Joint Statement from the German Neurocritical Care Society and the Neurocritical Care Society, Katja E. Wartenberg, David Y. Hwang, Karl Georg Haeusler, Susanne Muehlschlegel, Oliver W. Sakowitz, Dominik Madzar, Hajo M. Hamer, Alejandro A. Rabinstein, David M. Greer, J. Claude Hemphill 3rd, Juergen Meixensberger, and Panayiotis N. Varelas

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Hypomorphic mutations of TRIP11 cause odontochondrodysplasia, Anika Wehrle, John A. Follit, Gregory J. Pazour, Andrea Superti-Furga, Martin Lowe, and Ekkehart Lausch

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IIV-6 Inhibits NF-kappaB Responses in Drosophila, Cara C. West, Florentina Rus, Ying Chen, Anni Kleino, Monique Gangloff, Don B. Gammon, and Neal S. Silverman

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Hepatic Epithelioid Angiomyolipoma Treated with Laparoscopic Resection: Case Report and Review of the Literature, Chloe H. Williams, Kelli Hickle, Katherine Bakke, Sarah Jamshed, and Adel Bozorgzadeh

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Expression of mitochondrial membrane-linked SAB determines severity of sex-dependent acute liver injury, Sanda Win, Robert W. M. Min, Christopher Q. Chen, Jun Zhang, Yibu Chen, Meng Li, Ayako Suzuki, Manal F. Abdelmalek, Ying Wang, Mariam Aghajan, Filbert W. M. Aung, Anna Mae Diehl, Roger J. Davis, Tin A. Than, and Neil Kaplowitz

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Calcineurin broadly regulates the initiation of skeletal muscle-specific gene expression by binding target promoters and facilitating the interaction of the SWI/SNF chromatin remodeling enzyme, Hanna Witwicka, Jumpei Nogami, Sabriya A. Syed, Kazumitsu Maehara, Teresita Padilla-Benavides, Yasuyuki Ohkawa, and Anthony N. Imbalzano

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TRAV1-2(+) CD8(+) T-cells including oligoconal expansions of MAIT cells are enriched in the airways in human tuberculosis, Emily B. Wong, Samuel M. Behar, and David M. Lewinsohn

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RIPK1 Mediates TNF-Induced Intestinal Crypt Apoptosis During Chronic NF-kappaB Activation, Jerry Wong, Matija Zelic, John Bertin, Michelle A. Kelliher, and Monica Guma

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Reduced Brain Activity in the Right Putamen as an Early Predictor for Treatment Response in Drug-Naive, First-Episode Schizophrenia, Renrong Wu, Yangpan Ou, Feng Liu, Jindong Chen, Huabing Li, Jingping Zhao, Wenbin Guo, and Xiaoduo Fan

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Potent Enhancement of HIV-1 Replication by Nef in the Absence of SERINC3 and SERINC5, Yuanfei Wu, Balaji Olety, Eric R. Weiss, Elena Popova, Hikaru Yamanaka, and Heinrich G. Gottlinger

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MDT-28/PLIN-1 mediates lipid droplet-microtubule interaction via DLC-1 in Caenorhabditis elegans, Kang Xie, Peng Zhang, Huimin Na, Yangli Liu, Hong Zhang, and Pingsheng Liu

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SENP3-mediated host defense response contains HBV replication and restores protein synthesis, Rui Xi, Botao Liu, Yan Han, and Xiling Shen

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Automated Text Messaging With Patients in Department of Veterans Affairs Specialty Clinics: Cluster Randomized Trial, Vera Yakovchenko, Timothy P. Hogan, Thomas K. Houston, Lorilei Richardson, Jessica Lipschitz, Beth Ann Petrakis, Chris Gillespie, and D. Keith McInnes

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HSP90/AXL/eIF4E-regulated unfolded protein response as an acquired vulnerability in drug-resistant KRAS-mutant lung cancer, Haitang Yang, Shun-Qing Liang, Duo Xu, Zhang Yang, Thomas M. Marti, Yanyun Gao, Gregor J. Kocher, Heng Zhao, Ralph A. Schmid, and Ren-Wang Peng

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Control of antiviral innate immune response by protein geranylgeranylation, Shigao Yang, Zhaozhao Jiang, Katherine A. Fitzgerald, and Donghai Wang

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Bone-targeting AAV-mediated silencing of Schnurri-3 prevents bone loss in osteoporosis, Yeon-Suk Yang, Jun Xie, Dan Wang, Jung-Min Kim, Phillip W. L. Tai, Ellen M. Gravallese, Guangping Gao, and Jae-Hyuck Shim

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Measuring the reproducibility and quality of Hi-C data, Galip Gurkan Yardimci, Hakan Ozadam, Bryan R. Lajoie, Ye Zhan, Job Dekker, and William S. Noble

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Zebrafish prdm12b acts independently of nkx6.1 repression to promote eng1b expression in the neural tube p1 domain, Ozge Yildiz, Gerald B. Downes, and Charles G. Sagerstrom

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AK002, a Humanized Sialic Acid-Binding Immunoglobulin-Like Lectin-8 Antibody that Induces Antibody-Dependent Cell-Mediated Cytotoxicity against Human Eosinophils and Inhibits Mast Cell-Mediated Anaphylaxis in Mice, Bradford A. Youngblood, Emily C. Brock, John Leung, Rustom Falahati, Paul J. Bryce, Jessica Bright, Jason Williams, Leonard D. Shultz, Dale L. Greiner, Michael A. Brehm, Christopher Bebbington, and Nenad Tomasevic

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TARGET(R) Intracranial Aneurysm Coiling Prospective Multicenter Registry: Final Analysis of Peri-Procedural and Long-Term Safety and Efficacy Results, Osama O. Zaidat and Ajit S. Puri

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A Cohesin Subunit Variant Identified from a Peripheral Sclerocornea Pedigree, Bi Ning Zhang, Tommy Chung Yan Chan, Pancy Oi Sin Tam, Yu Liu, Chi Pui Pang, Vishal Jhanji, Li Jia Chen, and Wai Kit Chu

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Neutral diagnosis: An innovative concept for medical device clinical trials, Bo Zhang, Shangyuan Ye, Sravya B. Shankara, Hui Zhang, and Qingfeng Zheng

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Exploiting Unique Biological Features of Leukemia Stem Cells for Therapeutic Benefit, Haojian Zhang and Shaoguang Li

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Curing hemophilia A by NHEJ-mediated ectopic F8 insertion in the mouse, Jian-Ping Zhang, Xin-Xin Cheng, Mei Zhao, Guo-Hua Li, Jing Xu, Feng Zhang, Meng-Di Yin, Fei-Ying Meng, Xin-Yue Dai, Ya-Wen Fu, Zhi-Xue Yang, Cameron Arakaki, Ruijun Jeanna. Su, Wei Wen, Wen-Tian Wang, Wanqiu Chen, Hannah Choi, Charles Wang, Guangping Gao, Lei Zhang, Tao Cheng, and Xiao-Bing Zhang

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Mixed methods to explore factors associated with the decline of patients in the methadone maintenance treatment program in Shanghai, China, Lei Zhang, Jiayi Bao, Amy L. Harrington, Xiaoduo Fan, Zhen Ning, Jingying Zhang, Daqing Shi, Manji Hu, Zhirong Zhou, Zhengyi Cai, Min Zhao, and Jiang Du

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Proteome of the central apparatus of a ciliary axoneme, Lei Zhao, Yuqing Hou, Tyler Picariello, Branch Craige, and George B. Witman

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MicroRNA-29a activates a multi-component growth and invasion program in glioblastoma, Yun Zhao, Wei Huang, Tae-Min Kim, Yuchae Jung, Lata G. Menon, Hongyan Xing, Hongwei Li, Rona S. Carroll, Peter J. Park, Hong Wei Yang, and Mark D. Johnson

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Repetitive transcranial magnetic stimulation as an adjunctive treatment for negative symptoms and cognitive impairment in patients with schizophrenia: a randomized, double-blind, sham-controlled trial, Kaiming Zhuo, Yingying Tang, Zhenhua Song, Yingchan Wang, Junjie Wang, Zhenying Qian, Hui Li, Qiong Xiang, Tianyi Chen, Zhilei Yang, Yifeng Xu, Xiaoduo Fan, Jijun Wang, and Dengtang Liu

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Tethering of vesicles to the Golgi by GMAP210 controls LAT delivery to the immune synapse, Andres Ernesto Zucchetti, Laurence Bataille, Jean-Marie Carpier, Stephanie Dogniaux, Mabel San Roman-Jouve, Mathieu Maurin, Michael W. Stuck, Rosa M. Rios, Cosima T. Baldari, Gregory J. Pazour, and Claire Hivroz

Publications from 2018

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Impact of delirium on patients hospitalized for myocardial infarction: A propensity score analysis of the National Inpatient Sample, Abdullah Abdullah, George Eigbire, Amr Salama, Abdul Wahab, Mohanad Awadalla, Ryan Hoefen, and Richard Alweis

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Dual Use of a Patient Portal and Clinical Video Telehealth by Veterans with Mental Health Diagnoses: Retrospective, Cross-Sectional Analysis, Erica A. Abel, Stephanie L. Shimada, Karen Wang, Christine Ramsey, Melissa Skanderson, Joseph Erdos, Linda Godleski, Thomas K. Houston, and Cynthia A. Brandt

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TIP55, a splice isoform of the KAT5 acetyltransferase, is essential for developmental gene regulation and organogenesis, Diwash Acharya, Bernadette Nera, Zachary J. Milstone, Lauren Bourke, Yeonsoo Yoon, Jaime A. Rivera-Pérez, Chinmay M. Trivedi, and Thomas G. Fazzio

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Reduced Incidence and Better Liver Disease Outcomes among Chronic HCV Infected Patients Who Consume Cannabis, Adeyinka Adejumo, Oluwole Muyiwa Adegbala, Kelechi Lauretta Adejumo, and Terence N. Bukong

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Bayesian nonparametric discovery of isoforms and individual specific quantification, Derek Aguiar, Li-Fang Cheng, Bianca Dumitrascu, Fantine Mordelet, Athma A. Pai, and Barbara E. Engelhardt

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Wrist Arthritis, Hossein Akhondi and Sreelakshmi Panginikkod

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The Morbidity and Mortality of Laparoscopic Appendectomy in Patients with Cirrhosis, Yasir Al-Azzawai, Yasir Al-Abboodi, Matthew J. Fasullo, and Tarek Najuib

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Video Capsule Endoscopy in the Assessment of Portal Hypertensive Enteropathy, Yasir Al-Azzawai, Lidia Spaho, Mohammed Mahmoud, Joan Kheder, Anne Foley, and David R. Cave

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The comparative genomics of Bifidobacterium callitrichos reflects dietary carbohydrate utilization within the common marmoset gut, Korin Albert, Asha Rani, and David A. Sela

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Draft Genome Sequence of Bifidobacterium longum UMA026, Isolated from Holstein Dairy Cow Feces, Korin Albert and David Sela

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A population of gut epithelial enterochromaffin cells is mechanosensitive and requires Piezo2 to convert force into serotonin release, Constanza Alcaino, Kaitlyn R. Knutson, Anthony J. Treichel, Gulcan Yildiz, Peter R. Strege, David R. Linden, Joyce H. Li, Andrew B. Leiter, Joseph H. Szurszewski, Gianrico Farrugia, and Arthur Beyder

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Do Poor Prognostic Factors in Rheumatoid Arthritis Affect Treatment Choices and Outcomes? Analysis of a US Rheumatoid Arthritis Registry, Evo Alemao, Heather J. Litman, Sean E. Connolly, Sheila Kelly, Winnie Hua, Lisa Rosenblatt, Sabrina Rebello, Joel M. Kremer, and Leslie R. Harrold

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Cerebral organoids derived from Sandhoff disease-induced pluripotent stem cells exhibit impaired neurodifferentiation, Maria L. Allende, Emily K. Cook, Bridget C. Larman, Adrienne Nugent, Jacqueline M. Brady, Diane Golebiowski, Miguel Sena-Esteves, Cynthia J. Tifft, and Richard L. Proia

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New Vaccine Formulations Containing a Modified Version of the Amastigote 2 Antigen and the Non-Virulent Trypanosoma cruzi CL-14 Strain Are Highly Antigenic and Protective against Leishmania infantum Challenge, Ana Paula M. M. Almeida, Leopoldo F.M. Machado, Daniel Doro, Frederico C. Nascimento, Leonardo Damasceno, Ricardo T. Gazzinelli, Ana Paula Fernandes, and Caroline Junqueira

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NmeCas9 is an intrinsically high-fidelity genome-editing platform, Nadia Amrani, Xin D. Gao, Pengpeng Liu, Alireza Edraki, Aamir Mir, Raed Ibraheim, Ankit Gupta, Kanae E. Sasaki, Tong Wu, Thomas G. Fazzio, Lihua Julie Zhu, Scot A. Wolfe, and Erik J. Sontheimer

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Genetic Activation, Inactivation, and Deletion Reveal a Limited And Nuanced Role for Somatostatin-Containing Basal Forebrain Neurons in Behavioral State Control, Christelle Anaclet, Roberto De Luca, Anne Venner, Olga Malyshevskaya, Michael Lazarus, Elda Arrigoni, and Patrick M. Fuller

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Drug-Resistance and Population Structure of Plasmodium falciparum Across the Democratic Republic of Congo Using High-Throughput Molecular Inversion Probes, Ozkan Aydemir, Nicholas J. Hathaway, Patrick W. Marsh, Alice Tran, Thomas Reimonn, and Jeffrey A. Bailey

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Haplotype analysis of APOE intragenic SNPs, Vladimir N. Babenko, Dmitry A. Afonnikov, Elena V. Ignatieva, Anton V. Klimov, Fedor E. Gusev, and Evgeny I. Rogaev

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Ectopic high endothelial venules in pancreatic ductal adenocarcinoma: A unique site for targeted delivery, Baharak Bahmani, Mayuko Uehara, Farideh Ordikhani, Xiaofei Li, Liwei Jiang, Naima Banouni, Takaharu Ichimura, Vivek Kasinath, Siawosh K. Eskandari, Nasim Annabi, Jonathan S. Bromberg, Leonard D. Shultz, Dale L. Greiner, and Reza Abdi

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Macular phototoxicity after corneal cross-linking, Paulo Rodolfo Barbisan Tagliari, Marina Goncalves Viturino Monteiro, Fernanda Maria Souto Silveira, Bo Tian, Roberto Damian Pacheco Pinto, Lucas Barasnevicius Quagliato, Mauricio Abujamra Nascimento, Rosane Silvestre de Castro, and Carlos Eduardo Arieta Leite

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RIPK1-RIPK3-MLKL-Associated Necroptosis Drives Leishmania infantum Killing in Neutrophils, Laiana A. Barbosa, Paloma P. Fiuza, Leticia J. Borges, Fellipe A. Rolim, Mayara B. Andrade, Nivea F. Luz, Graziele Quintela-Carvalho, Jonilson B. Lima, Roque P. Almeida, Francis Ka-Ming Chan, Marcelo T. Bozza, Valeria M. Borges, and Deboraci B. Prates

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Anxiety, Depression, and Adverse Clinical Outcomes in Patients With Atrial Fibrillation Starting Warfarin: Cardiovascular Research Network WAVE Study, Christine Baumgartner, Dongjie Fan, Margaret C. Fang, Daniel E. Singer, Daniel M. Witt, John R. Schmelzer, Marc S. Williams, Jerry H. Gurwitz, Sue Hee Sung, and Alan S. Go

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Evaluation of a method to measure HHV-6B infection in vitro based on cell size, Aniuska Becerra, Tessa Santoro, and Lawrence J. Stern

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Are membranes non-apoptotic compartments for apoptotic caspases, Andreas Bergmann

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Allostatic Load Biomarker Associations with Depressive Symptoms Vary among US Black and White Women and Men, Ganga Bey, William M. Jesdale, Christine M. Ulbricht, Eric O. Mick, and Sharina D. Person

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Analysis and Correction of Inappropriate Image Duplication: the Molecular and Cellular Biology Experience, Elisabeth M. Bik, Ferric C. Fang, Amy L. Kullas, Roger J. Davis, and Arturo Casadevall

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Safety and efficacy of subcutaneous tanezumab in patients with knee or hip osteoarthritis, Charles Birbara, Eugene J. Dabezies Jr, Aimee M. Burr, Robert J. Fountaine, Michael D. Smith, Mark T. Brown, Christine R. West, Rosalin H. Arends, and Kenneth M. Verburg

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Exploring the Emergence of RNA Nucleosides and Nucleotides on the Early Earth, Annabelle Biscans

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Efficacy of a respiratory syncytial virus vaccine candidate in a maternal immunization model, Jorge C. G. Blanco, Lioubov M. Pletneva, Lori McGinnes Cullen, Raymonde O. Otoa, Mira C. Patel, Lurds R. Fernando, Marina S. Boukhvalova, and Trudy G. Morrison

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Study protocol: a hybrid effectiveness-implementation trial of Moral Reconation Therapy in the US Veterans Health Administration, Daniel M. Blonigen, Michael A. Cucciare, Christine Timko, Jennifer S. Smith, Autumn Harnish, Lakiesha Kemp, Joel Rosenthal, and David A. Smelson

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Orthogonal Cas9-Cas9 chimeras provide a versatile platform for genome editing, Mehmet F. Bolukbasi, Pengpeng Liu, Kevin Luk, Samantha F. Kwok, Ankit Gupta, Nadia Amrani, Erik J. Sontheimer, Lihua Julie Zhu, and Scot A. Wolfe

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Nasopharyngeal Exposure to Streptococcus pneumoniae Induces Extended Age-Dependent Protection against Pulmonary Infection Mediated by Antibodies and CD138(+) Cells, Elsa N. Bou Ghanem, Nang H. Maung, Nalat Siwapornchai, Aaron E. Goodwin, Stacie Clark, Ernesto J. Munoz-Elias, Andrew Camilli, Rachel M. Gerstein, and John M. Leong

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Synergistic assembly of human pre-spliceosomes across introns and exons, Joerg E. Braun, Larry J. Friedman, Jeff Gelles, and Melissa J. Moore

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Can Mindfulness Address Maladaptive Eating Behaviors? Why Traditional Diet Plans Fail and How New Mechanistic Insights May Lead to Novel Interventions, Judson A. Brewer, Andrea Ruf, Ariel Beccia, Gloria I. Essien, Leonard M. Finn, Remko van Lutterveld, and Ashley E. Mason

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alpha Cell Function and Gene Expression Are Compromised in Type 1 Diabetes, Marcela Brissova, David Blodgett, Dale L. Greiner, David M. Harlan, and Alvin C. Powers

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Maximising the global health impact of future HIV cure-related interventions through advance planning, Regina Brown, Steven G. Deeks, and Nir Eyal

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A Comparative Study of Single and Dual Perfusion During End-ischemic Subnormothermic Liver Machine Preservation, Isabel M. A. Bruggenwirth, Carolina Moore, Paria Mahboub, Max F. Thijssen, Xiaofei E, Henri G. D. Leuvenink, Pranoti Mandrekar, Xiaofei Wang, Timothy F. Kowalik, Robert J. Porte, and Paulo N.A. Martins