Open Access is free, unrestricted, online access to scientific and scholarly research. This collection includes Open Access journal articles and other materials authored by researchers, faculty, staff, and students at UMass Chan Medical School.

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Publications from 1994

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Mutational activation of the STE5 gene product bypasses the requirement for G protein beta and gamma subunits in the yeast pheromone response pathway, Miriam Sarah Hasson, Dmitry B. Blinder, Jeremy Thorner, and Duane D. Jenness

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Ponticulin is the major high affinity link between the plasma membrane and the cortical actin network in Dictyostelium, Anne L. Hitt, J. H. Hartwig, and Elizabeth J. Luna

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Ponticulin is an atypical membrane protein, Anne L. Hitt, Tze Hong Lu, and Elizabeth J. Luna

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Investigations of ascorbate for direct labeling of antibodies with technetium-99m, Donald J. Hnatowich, F. Virzi, Paul T. Winnard, M. Fogarasi, and Mary Rusckowski

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Lethargy, confusion, and a mediastinal abnormality in a 68-year-old woman, Helen M. Hollingsworth, Kevin H. Silver, Richard S. Irwin, and Gerard P. Aurigemma

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The Saccharomyces cerevisiae oligosaccharyltransferase is a protein complex composed of Wbp1p, Swp1p, and four additional polypeptides, Daniel J. Kelleher and Reid Gilmore

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Analysis of inhibitors of bacteriophage T4 DNA polymerase, Naseema N. Khan, Linda J. Reha-Krantz, and George E. Wright

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Sequences responsible for intracellular localization of beta-actin messenger RNA also affect cell phenotype, Edward H. Kislauskis, Xiaochun Zhu, and Robert H. Singer

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Tailored low-dose fluoroscopic voiding cystourethrography for the reevaluation of vesicoureteral reflux in girls, Paul K. Kleinman, David A. Diamond, Andrew Karellas, Melissa R. Spevak, Katherine Nimkin, and Patricia L. Belanger

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The RNA polymerase I transcription factor, upstream binding factor, interacts directly with the TATA box-binding protein, Hyockman Kwon and Michael R. Green

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Structure and transcriptional regulation of the Escherichia coli adaptive response gene aidB, Paolo Landini, Laurel I. Hajec, and Michael R. Volkert

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Neutrophil cathepsin G modulates the platelet surface expression of the glycoprotein (GP) Ib-IX complex by proteolysis of the von Willebrand factor binding site on GPIb alpha and by a cytoskeletal-mediated redistribution of the remainder of the complex, Charles A. LaRosa, Michael J. Rohrer, Stephen E. Benoit, Marc R. Barnard, and Alan D. Michelson

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Beta-actin mRNA localization is regulated by signal transduction mechanisms, Vaughan M. Latham, Edward H. Kislauskis, Robert H. Singer, and Anthony F. Ross

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Differential expression of thyroid hormone receptor isoforms in neurons and astroglial cells, Jack L. Leonard, Alan P. Farwell, Paul M. Yen, William W. Chin, and Martin Stula

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Dipyridamole myocardial perfusion imaging, Jeffrey A. Leppo

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Recognition of envelope protein by dengue virus serotype-specific human CD4+ CD8- cytotoxic T-cell clones, Peter G. Livingston, Ichiro Kurane, Ching-Juh Lai, Michael Bray, and Francis A. Ennis

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A monomeric protein in the Golgi membrane catalyzes both N-deacetylation and N-sulfation of heparan sulfate, Elisabet C. Mandon, Ellis S. Kempner, Masayuki Ishihara, and Carlos B. Hirschberg

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Purification of the Golgi adenosine 3'-phosphate 5'-phosphosulfate transporter, a homodimer within the membrane, Elisabet C. Mandon, Marcos E. Milla, Ellis S. Kempner, and Carlos B. Hirschberg

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Human transcription factor YY1 represses human immunodeficiency virus type 1 transcription and virion production, David M. Margolis, Mohan Somasundaran, and Michael R. Green

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Unfixed cryosections of striated muscle to study dynamic molecular events, Jean-Francois Menetret and Roger W. Craig

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The activation-induced decrease in the platelet surface expression of the glycoprotein Ib-IX complex is reversible, Alan D. Michelson, Stephen E. Benoit, Michael H. Kroll, Jian-ming Li, Michael J. Rohrer, Anita S. Kestin, and Marc R. Barnard

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Site-directed mutagenesis of a conserved hexapeptide in the paramyxovirus hemagglutinin-neuraminidase glycoprotein: effects on antigenic structure and function, Anne M. Mirza, Ruitang Deng, and Ronald M. Iorio

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Biochemical characterization of P22 phage-modified Escherichia coli RecBCD enzyme, Kenan C. Murphy

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Identification of residues in the L1 region of the RecA protein which are important to recombination or coprotease activities, Horacio G. Nastri and Kendall L. Knight

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Chronic granulomatous disease and glutathione peroxidase deficiency, revisited, Peter E. Newburger, Stephen E. Malawista, Mary C. Dinauer, Terri Gelbart, Richard C. Woodman, Sunil Chada, Qichang Shen, Gretchen van Blaricom, Paul G. Quie, and John T. Curnutte

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Mutations in the promoter region of the gene for gp91-phox in X-linked chronic granulomatous disease with decreased expression of cytochrome b558, Peter E. Newburger, David G. Skalnik, Penelope J. Hopkins, Elizabeth A. Eklund, and John T. Curnutte

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Adrenal hemorrhage in abused children: imaging and postmortem findings, Katherine Nimkin, Susan Teeger, Michael T. Wallach, John C. DuVally, Melissa R. Spevak, and Paul K. Kleinman

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Susceptibility to cytotoxic T lymphocyte-induced apoptosis is a function of the proliferative status of the target, Walter K. Nishioka and Raymond M. Welsh

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Molecular cloning and expression of a glycosaminoglycan N-acetylglucosaminyl N-deacetylase/N-sulfotransferase from a heparin-producing cell line, Ariel Orellana, Carlos B. Hirschberg, Zheng Wei, Stuart J. Swiedler, and Masayuki Ishihara

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Five SWI/SNF gene products are components of a large multisubunit complex required for transcriptional enhancement, Craig L. Peterson, Andrew K. Dingwall, and Matthew P. Scott

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Cholesterol and bile acids regulate cholesterol 7 alpha-hydroxylase expression at the transcriptional level in culture and in transgenic mice, Maria I. Ramirez, Denise Karaoglu, Diego Haro, Carmen Barillas, Roya Bashirzadeh, and Gregorio Gil

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Signal sequence recognition and targeting of ribosomes to the endoplasmic reticulum by the signal recognition particle do not require GTP, Peter J. Rapiejko and Reid Gilmore

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Repression of ALA synthase by heme and zinc-mesoporphyrin in a chick embryo liver cell culture model of acute porphyria, Shirley M. Russo, Joyce A. Pepe, Edward Earl Cable, Richard W. Lambrecht, and Herbert L. Bonkovsky

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Direct evidence for ligand-induced internalization of the yeast alpha-factor pheromone receptor, Kimberly A. Schandel and Duane D. Jenness

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Cross-reactivities in memory cytotoxic T lymphocyte recognition of heterologous viruses, Liisa K. Selin, Sharon R. Nahill, and Raymond M. Welsh

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Mutations in the fusion peptide and heptad repeat regions of the Newcastle disease virus fusion protein block fusion, Theresa A. Sergel, Cathy McQuain, and Trudy G. Morrison

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Regulation of cellular interactions with laminin by integrin cytoplasmic domains: the A and B structural variants of the alpha 6 beta 1 integrin differentially modulate the adhesive strength, morphology, and migration of macrophages, Leslie M. Shaw and Arthur M. Mercurio

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Regulation of the human cellular glutathione peroxidase gene during in vitro myeloid and monocytic differentiation, Qichang Shen, Sunil Chada, Constance Whitney, and Peter E. Newburger

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Differential intracellular localizations of GDP dissociation inhibitor isoforms. Insulin-dependent redistribution of GDP dissociation inhibitor-2 in 3T3-L1 adipocytes, Assia Shisheva, Joanne M. Buxton, and Michael P. Czech

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Cloning, characterization, and expression of a novel GDP dissociation inhibitor isoform from skeletal muscle, Assia Shisheva, Thomas C. Sudhof, and Michael P. Czech

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Functionally important residues at a subunit interface site in the RecA protein from Escherichia coli, Mark C. Skiba and Kendall L. Knight

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Signal transduction by tumor necrosis factor mediated by JNK protein kinases, Hayla Karen Sluss, Tamera Barrett, Benoit Derijard, and Roger J. Davis

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Localization of HIV RNA in mitochondria of infected cells: potential role in cytopathogenicity, Mohan Somasundaran, Maria L. Zapp, Lars K. Beattie, Lizhen Pang, Kevin S. Byron, Gary J. Bassell, John L. Sullivan, and Robert H. Singer

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Growth hormone stimulates tyrosine phosphorylation of insulin receptor substrate-1, Sandra C. Souza, G. Peter Frick, Rupert Guk-Chor Yip, Raysildo B. Lobo, Lih-Ruey Tai, and H. Maurice Goodman

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Acute, lethal, natural killer cell-resistant myeloproliferative disease induced by polyomavirus in severe combined immunodeficient mice, Eva Szomolanyi-Tsuda, Patricia L. Dundon, Isabelle Joris, Leonard D. Shultz, Bruce A. Woda, and R M Welsh

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Subtype cross-reactive, infection-enhancing antibody responses to influenza A viruses, Manabu Tamura, Robert G. Webster, and Francis A. Ennis

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Effects of fibroblast growth factor on type I 5'-deiodinase in FRTL-5 rat thyroid cells, Kam-Tsun Tang, Lewis E. Braverman, and William J. DeVito

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Integrin alpha 6 beta 4 mediates dynamic interactions with laminin, Aydin Tozeren, Hynda K. Kleinman, Stephen Wu, Arthur M. Mercurio, and Stephen W. Byers

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Transcription of histone H4, H3, and H1 cell cycle genes: promoter factor HiNF-D contains CDC2, cyclin A, and an RB-related protein, Andre J. Van Wijnen, Farah Aziz, Xavier Grana, Antonio De Luca, Rajesh K. Desai, Karen Jaarsveld, Thomas J. Last, Kenneth J. Soprano, Antonio Giordano, and Jane B. Lian

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Induction of the Escherichia coli aidB gene under oxygen-limiting conditions requires a functional rpoS (katF) gene, Michael R. Volkert, Laurel I. Hajec, Zdenka Matijasevic, Ferric C. Fang, and Robert Prince

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The delta (argF-lacZ)205(U169) deletion greatly enhances resistance to hydrogen peroxide in stationary-phase Escherichia coli, Michael R. Volkert, Peter C. Loewen, Jacek Switala, David Crowley, and Matthew Conley

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Ethanol directly modulates gating of a dihydropyridine-sensitive Ca2+ channel in neurohypophysial terminals, Xiaoming Wang, Gang Wang, Jose R. Lemos, and Steven N. Treistman

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The native structure of the activated Raf protein kinase is a membrane-bound multi-subunit complex, Markus Wartmann and Roger J. Davis

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Molecular analysis of the gamma heavy chain of Chlamydomonas flagellar outer-arm dynein, Curtis G. Wilkerson, Stephen M. King, and George B. Witman (Journal of cell science)

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Dominant negative mutator mutations in the mutS gene of Escherichia coli, Te-hui Wu and Martin G. Marinus

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Sexually transmitted diseases: a neglected public health priority, Alfred Yankauer

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Temporal trends and factors associated with pulmonary artery catheterization in patients with acute myocardial infarction, Jorge L. Yarzebski, Robert J. Goldberg, Joel M. Gore, and Joseph S. Alpert

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A 32P-postlabeling method for detecting unstable N-7-substituted deoxyguanosine adducts in DNA, Dong Yu, Tian-Qi Niu, Paula Austin-Ritchie, and David B. Ludlum

Publications from 1993

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Guanosine diphosphatase is required for protein and sphingolipid glycosylation in the Golgi lumen of Saccharomyces cerevisiae, Claudia Abeijon, Ken Yanagisawa, Elisabet C. Mandon, Alex Hausler, Kelley W. Moremen, Carlos B. Hirschberg, and Phillips W. Robbins

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Constitutive transcription of the osteocalcin gene in osteosarcoma cells is reflected by altered protein-DNA interactions at promoter regulatory elements, Rita Bortell, T. A. Owen, Victoria Shalhoub, A Heinrichs, Michael A. Aronow, C Rochette-Egly, Y Lutz, Janet L. Stein, Jane B. Lian, and Gary S. Stein

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Infection of peripancreatic lymph nodes but not islets precedes Kilham rat virus-induced diabetes in BB/Wor rats, David W. Brown, Raymond M. Welsh, and Arthur A. Like

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Detection of thyrotropin binding inhibitory activity in neonatal blood spots, Rosalind S. Brown, Ronald L. Bellisario, Elizabeth Mitchell, Paula Keating, and Diego Botero

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Repair of heteroduplex DNA molecules with multibase loops in Escherichia coli, Margaretha Carraway and Martin G. Marinus

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Redistribution of clathrin-coated vesicle adaptor complexes during adipocytic differentiation of 3T3-L1 cells, Ranjan Chakrabarti, Marguerite Joly, and Silvia Corvera

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The thyroid gland is a major source of circulating T3 in the rat, Jean-Pierre Chanoine, Lewis E. Braverman, Alan P. Farwell, Marjorie Safran, Sharon Alex, Susan A. Dubord-Tomasetti, and Jack L. Leonard

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The postnatal serum 3,5,3'-triiodothyronine (T3) surge in the rat is largely independent of extrathyroidal 5'-deiodination of thyroxine to T3, Jean-Pierre Chanoine, Irini E. Veronikis, Sharon Alex, Scott Stone, Shih-Lieh Fang, Jack L. Leonard, and Lewis E. Braverman

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Pharmacokinetics of nevirapine: initial single-rising-dose study in humans, Sarah H. Cheeseman, Susan E. Hattox, Margaret M. McLaughlin, Richard A. Koup, Charla A. Andrews, Carol A. Bova, Joseph W. Pav, Tapon Roy, John L. Sullivan, and James J. Keirns

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The integral membrane protein, ponticulin, acts as a monomer in nucleating actin assembly, C. P. Chia, A. Shariff, S. A. Savage, and Elizabeth J. Luna

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GTP hydrolysis by complexes of the signal recognition particle and the signal recognition particle receptor, Timothy Connolly and Reid Gilmore

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Insulin action on the internalization of the GLUT4 glucose transporter in isolated rat adipocytes, Michael P. Czech and Joanne M. Buxton

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Exofacial epitope-tagged glucose transporter chimeras reveal COOH-terminal sequences governing cellular localization, Michael P. Czech, Anil Chawla, Chee-Wai Woon, Joanne M. Buxton, Michal Armoni, Wei Tang, Marguerite Joly, and Silvia Corvera

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Myocardial extraction of technetium-99m-[2-(1-methoxybutyl) isonitrile] in the isolated rabbit heart: a myocardial perfusion agent with high extraction and stable retention, Seth T. Dahlberg, Denis J. Meerdink, Madeleine P. Gilmore, and Jeffrey A. Leppo

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Rochalimaea elizabethae sp. nov. isolated from a patient with endocarditis, Jennifer S. Daly, Michael G. Worthington, Don J. Brenner, C. Wayne Moss, Dannie G. Hollis, Robbin S. Weyant, Arnold G. Steigerwalt, Robert E. Weaver, Maryam I. Daneshvar, and Steven P. O'Connor

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The mitogen-activated protein kinase signal transduction pathway, Roger J. Davis

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Vaccinia virus-specific CD8+ cytotoxic T lymphocytes in humans, Walter E. Demkowicz and Francis A. Ennis

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A complication involving a braided hook-wire localization device, Carl J. D'Orsi, Richard S. Swanson, Lawrence J. Moss, Frank R. Reale, and Michael D. Wertheimer

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Thyroxine targets different pathways of internalization of type II iodothyronine 5'-deiodinase in astrocytes, Alan P. Farwell, David J. DiBenedetto, and Jack L. Leonard

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DNA vaccines: protective immunizations by parenteral, mucosal, and gene-gun inoculations, Ellen F. Fynan, Robert G. Webster, D H Fuller, Joel R. Haynes, Joseph C. Santoro, and Harriet L. Robinson

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Serum-induced translocation of mitogen-activated protein kinase to the cell surface ruffling membrane and the nucleus, Fernando A. Gonzalez, Alpna Seth, David L. Raden, Douglas S. Bowman, Fredric S. Fay, and Roger J. Davis

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Dengue virus-specific human CD4+ T-lymphocyte responses in a recipient of an experimental live-attenuated dengue virus type 1 vaccine: bulk culture proliferation, clonal analysis, and precursor frequency determination, Sharone Green, Ichiro Kurane, Robert Edelman, Carol 0. Tacket, Kenneth H. Eckels, David W. Vaughn, Charles H. Hoke, and Francis A. Ennis

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Stabilization and ribosome association of unspliced pre-mRNAs in a yeast upf1- mutant, Feng He, Stuart W. Peltz, Janet L. Donahue, Michael Rosbash, and Allan Jacobson

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Directly and indirectly technetium-99m-labeled antibodies--a comparison of in vitro and animal in vivo properties, Donald J. Hnatowich, George Mardirossian, Mary Rusckowski, M. Fogarasi, F. Virzi, and Paul T. Winnard

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ptx1, a nonphototactic mutant of Chlamydomonas, lacks control of flagellar dominance, Cynthia J. Horst and George B. Witman (The Journal of cell biology)

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Difficult-to-control asthma. Contributing factors and outcome of a systematic management protocol, Richard S. Irwin, Frederick J. Curley, and Cynthia L. French

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Chronic cough due to gastroesophageal reflux. Clinical, diagnostic, and pathogenetic aspects, Richard S. Irwin, Cynthia L. French, Frederick J. Curley, John K. Zawacki, and Frederick M. Bennett

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Quantitation of substance-P and its metabolites in plasma and synovial fluid from patients with arthritis, Terrence J. Joyce, Robert A. Yood, and Robert E. Carraway

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Isoform-specific 3'-untranslated sequences sort alpha-cardiac and beta-cytoplasmic actin messenger RNAs to different cytoplasmic compartments, Edward H. Kislauskis, Zhifang Li, Robert H. Singer, and Krishan L. Taneja

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Activation of protein kinases by insulin and non-hydrolyzable GTP analogs in permeabilized 3T3-L1 adipocytes, Jes K. Klarlund, Nazer Khalaf, Lynn M. Kozma, and Michael P. Czech

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The ras signaling pathway mimics insulin action on glucose transporter translocation, Lynn M. Kozma, Kurt Baltensperger, Jes K. Klarlund, A Porras, E Santos, and Michael P. Czech

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Definition of an HLA-DPw2-restricted epitope on NS3, recognized by a dengue virus serotype-cross-reactive human CD4+ CD8- cytotoxic T-cell clone, Ichiro Kurane, Li Chen Dai, Peter G. Livingston, Elaine Reed, and Francis A. Ennis

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The cAMP response element binding protein, CREB, is a potent inhibitor of diverse transcriptional activators, Frederic P. Lemaigre, Christopher I. Ace, and Michael R. Green

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Androgen and estrogen dynamics: relationships with age, weight, and menopausal status, Christopher Longcope and Stephen P. Baker

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Neuraminidase augments Fc gamma receptor II-mediated antibody-dependent enhancement of dengue virus infection, Brian Mady, Ichiro Kurane, David V. Erbe, Michael W. Fanger, and Francis A. Ennis

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Mutational analysis of the Saccharomyces cerevisiae general regulatory factor CP1, Daniel C. Masison, Kevin F. O'Connell, and Richard E. Baker

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Protection against chloroethylnitrosourea cytotoxicity by eukaryotic 3-methyladenine DNA glycosylase, Zdenka Matijasevic, M Boosalis, W Mackay, L Samson, and David B. Ludlum

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Characterization of a DNA mismatch-binding activity in yeast extracts, Juan J. Miret, Maria G. Milla, and Robert S. Lahue

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Structure and function of a membrane anchor-less form of the hemagglutinin-neuraminidase glycoprotein of Newcastle disease virus, Anne M. Mirza, John P. Sheehan, Larry W. Hardy, Rhona L. Glickman, and Ronald M. Iorio

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Isoproterenol stimulates rapid extrusion of sodium from isolated smooth muscle cells, Edwin D. W. Moore and Fredric S. Fay

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Properties of Escherichia coli expressing bacteriophage P22 Abc (anti-RecBCD) proteins, including inhibition of Chi activity, Kenan C. Murphy and Laura J. Lewis

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High frequency of cross-reactive cytotoxic T lymphocytes elicited during the virus-induced polyclonal cytotoxic T lymphocyte response, Sharon R. Nahill and Raymond M. Welsh