Open Access is free, unrestricted, online access to scientific and scholarly research. This collection includes Open Access journal articles and other materials authored by researchers, faculty, staff, and students of the University of Massachusetts Medical School.

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Publications from 1994

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The native structure of the activated Raf protein kinase is a membrane-bound multi-subunit complex, Markus Wartmann and Roger J. Davis

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Molecular analysis of the gamma heavy chain of Chlamydomonas flagellar outer-arm dynein, Curtis G. Wilkerson, Stephen M. King, and George B. Witman (Journal of cell science)

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Dominant negative mutator mutations in the mutS gene of Escherichia coli, Te-hui Wu and Martin G. Marinus

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Sexually transmitted diseases: a neglected public health priority, Alfred Yankauer

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Temporal trends and factors associated with pulmonary artery catheterization in patients with acute myocardial infarction, Jorge L. Yarzebski, Robert J. Goldberg, Joel M. Gore, and Joseph S. Alpert

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A 32P-postlabeling method for detecting unstable N-7-substituted deoxyguanosine adducts in DNA, Dong Yu, Tian-Qi Niu, Paula Austin-Ritchie, and David B. Ludlum

Publications from 1993

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Guanosine diphosphatase is required for protein and sphingolipid glycosylation in the Golgi lumen of Saccharomyces cerevisiae, Claudia Abeijon, Ken Yanagisawa, Elisabet C. Mandon, Alex Hausler, Kelley W. Moremen, Carlos B. Hirschberg, and Phillips W. Robbins

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Constitutive transcription of the osteocalcin gene in osteosarcoma cells is reflected by altered protein-DNA interactions at promoter regulatory elements, Rita Bortell, T. A. Owen, Victoria Shalhoub, A Heinrichs, Michael A. Aronow, C Rochette-Egly, Y Lutz, Janet L. Stein, Jane B. Lian, and Gary S. Stein

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Infection of peripancreatic lymph nodes but not islets precedes Kilham rat virus-induced diabetes in BB/Wor rats, David W. Brown, Raymond M. Welsh, and Arthur A. Like

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Detection of thyrotropin binding inhibitory activity in neonatal blood spots, Rosalind S. Brown, Ronald L. Bellisario, Elizabeth Mitchell, Paula Keating, and Diego Botero

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Repair of heteroduplex DNA molecules with multibase loops in Escherichia coli, Margaretha Carraway and Martin G. Marinus

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Redistribution of clathrin-coated vesicle adaptor complexes during adipocytic differentiation of 3T3-L1 cells, Ranjan Chakrabarti, Marguerite Joly, and Silvia Corvera

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The thyroid gland is a major source of circulating T3 in the rat, Jean-Pierre Chanoine, Lewis E. Braverman, Alan P. Farwell, Marjorie Safran, Sharon Alex, Susan A. Dubord-Tomasetti, and Jack L. Leonard

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The postnatal serum 3,5,3'-triiodothyronine (T3) surge in the rat is largely independent of extrathyroidal 5'-deiodination of thyroxine to T3, Jean-Pierre Chanoine, Irini E. Veronikis, Sharon Alex, Scott Stone, Shih-Lieh Fang, Jack L. Leonard, and Lewis E. Braverman

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Pharmacokinetics of nevirapine: initial single-rising-dose study in humans, Sarah H. Cheeseman, Susan E. Hattox, Margaret M. McLaughlin, Richard A. Koup, Charla A. Andrews, Carol A. Bova, Joseph W. Pav, Tapon Roy, John L. Sullivan, and James J. Keirns

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The integral membrane protein, ponticulin, acts as a monomer in nucleating actin assembly, C. P. Chia, A. Shariff, S. A. Savage, and Elizabeth J. Luna

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GTP hydrolysis by complexes of the signal recognition particle and the signal recognition particle receptor, Timothy Connolly and Reid Gilmore

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Insulin action on the internalization of the GLUT4 glucose transporter in isolated rat adipocytes, Michael P. Czech and Joanne M. Buxton

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Exofacial epitope-tagged glucose transporter chimeras reveal COOH-terminal sequences governing cellular localization, Michael P. Czech, Anil Chawla, Chee-Wai Woon, Joanne M. Buxton, Michal Armoni, Wei Tang, Marguerite Joly, and Silvia Corvera

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Myocardial extraction of technetium-99m-[2-(1-methoxybutyl) isonitrile] in the isolated rabbit heart: a myocardial perfusion agent with high extraction and stable retention, Seth T. Dahlberg, Denis J. Meerdink, Madeleine P. Gilmore, and Jeffrey A. Leppo

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Rochalimaea elizabethae sp. nov. isolated from a patient with endocarditis, Jennifer S. Daly, Michael G. Worthington, Don J. Brenner, C. Wayne Moss, Dannie G. Hollis, Robbin S. Weyant, Arnold G. Steigerwalt, Robert E. Weaver, Maryam I. Daneshvar, and Steven P. O'Connor

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The mitogen-activated protein kinase signal transduction pathway, Roger J. Davis

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Vaccinia virus-specific CD8+ cytotoxic T lymphocytes in humans, Walter E. Demkowicz and Francis A. Ennis

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A complication involving a braided hook-wire localization device, Carl J. D'Orsi, Richard S. Swanson, Lawrence J. Moss, Frank R. Reale, and Michael D. Wertheimer

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Thyroxine targets different pathways of internalization of type II iodothyronine 5'-deiodinase in astrocytes, Alan P. Farwell, David J. DiBenedetto, and Jack L. Leonard

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DNA vaccines: protective immunizations by parenteral, mucosal, and gene-gun inoculations, Ellen F. Fynan, Robert G. Webster, D H Fuller, Joel R. Haynes, Joseph C. Santoro, and Harriet L. Robinson

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Serum-induced translocation of mitogen-activated protein kinase to the cell surface ruffling membrane and the nucleus, Fernando A. Gonzalez, Alpna Seth, David L. Raden, Douglas S. Bowman, Fredric S. Fay, and Roger J. Davis

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Dengue virus-specific human CD4+ T-lymphocyte responses in a recipient of an experimental live-attenuated dengue virus type 1 vaccine: bulk culture proliferation, clonal analysis, and precursor frequency determination, Sharone Green, Ichiro Kurane, Robert Edelman, Carol 0. Tacket, Kenneth H. Eckels, David W. Vaughn, Charles H. Hoke, and Francis A. Ennis

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Stabilization and ribosome association of unspliced pre-mRNAs in a yeast upf1- mutant, Feng He, Stuart W. Peltz, Janet L. Donahue, Michael Rosbash, and Allan Jacobson

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Directly and indirectly technetium-99m-labeled antibodies--a comparison of in vitro and animal in vivo properties, Donald J. Hnatowich, George Mardirossian, Mary Rusckowski, M. Fogarasi, F. Virzi, and Paul T. Winnard

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ptx1, a nonphototactic mutant of Chlamydomonas, lacks control of flagellar dominance, Cynthia J. Horst and George B. Witman (The Journal of cell biology)

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Difficult-to-control asthma. Contributing factors and outcome of a systematic management protocol, Richard S. Irwin, Frederick J. Curley, and Cynthia L. French

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Chronic cough due to gastroesophageal reflux. Clinical, diagnostic, and pathogenetic aspects, Richard S. Irwin, Cynthia L. French, Frederick J. Curley, John K. Zawacki, and Frederick M. Bennett

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Quantitation of substance-P and its metabolites in plasma and synovial fluid from patients with arthritis, Terrence J. Joyce, Robert A. Yood, and Robert E. Carraway

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Isoform-specific 3'-untranslated sequences sort alpha-cardiac and beta-cytoplasmic actin messenger RNAs to different cytoplasmic compartments, Edward H. Kislauskis, Zhifang Li, Robert H. Singer, and Krishan L. Taneja

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Activation of protein kinases by insulin and non-hydrolyzable GTP analogs in permeabilized 3T3-L1 adipocytes, Jes K. Klarlund, Nazer Khalaf, Lynn M. Kozma, and Michael P. Czech

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The ras signaling pathway mimics insulin action on glucose transporter translocation, Lynn M. Kozma, Kurt Baltensperger, Jes K. Klarlund, A Porras, E Santos, and Michael P. Czech

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Definition of an HLA-DPw2-restricted epitope on NS3, recognized by a dengue virus serotype-cross-reactive human CD4+ CD8- cytotoxic T-cell clone, Ichiro Kurane, Li Chen Dai, Peter G. Livingston, Elaine Reed, and Francis A. Ennis

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The cAMP response element binding protein, CREB, is a potent inhibitor of diverse transcriptional activators, Frederic P. Lemaigre, Christopher I. Ace, and Michael R. Green

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Androgen and estrogen dynamics: relationships with age, weight, and menopausal status, Christopher Longcope and Stephen P. Baker

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Neuraminidase augments Fc gamma receptor II-mediated antibody-dependent enhancement of dengue virus infection, Brian Mady, Ichiro Kurane, David V. Erbe, Michael W. Fanger, and Francis A. Ennis

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Mutational analysis of the Saccharomyces cerevisiae general regulatory factor CP1, Daniel C. Masison, Kevin F. O'Connell, and Richard E. Baker

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Protection against chloroethylnitrosourea cytotoxicity by eukaryotic 3-methyladenine DNA glycosylase, Zdenka Matijasevic, M Boosalis, W Mackay, L Samson, and David B. Ludlum

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Characterization of a DNA mismatch-binding activity in yeast extracts, Juan J. Miret, Maria G. Milla, and Robert S. Lahue

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Structure and function of a membrane anchor-less form of the hemagglutinin-neuraminidase glycoprotein of Newcastle disease virus, Anne M. Mirza, John P. Sheehan, Larry W. Hardy, Rhona L. Glickman, and Ronald M. Iorio

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Isoproterenol stimulates rapid extrusion of sodium from isolated smooth muscle cells, Edwin D. W. Moore and Fredric S. Fay

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Properties of Escherichia coli expressing bacteriophage P22 Abc (anti-RecBCD) proteins, including inhibition of Chi activity, Kenan C. Murphy and Laura J. Lewis

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High frequency of cross-reactive cytotoxic T lymphocytes elicited during the virus-induced polyclonal cytotoxic T lymphocyte response, Sharon R. Nahill and Raymond M. Welsh

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Progesterone regulation of endometrial estrogen receptor and cell proliferation during the late proliferative and secretory phase in artificial menstrual cycles in the rhesus monkey, William C. Okulicz, Melissa Balsamo, and Janet Tast

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Etidronate inhibits the thyroid hormone-induced bone loss in rats assessed by bone mineral density and messenger ribonucleic acid markers of osteoblast and osteoclast function, Boonsong Ongphiphadhanakul, Louis G. Jenis, Lewis E. Braverman, Sharon Alex, Gary S. Stein, Jane B. Lian, and Daniel T. Baran

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Postproliferative transcription of the rat osteocalcin gene is reflected by vitamin D-responsive developmental modifications in protein-DNA interactions at basal and enhancer promoter elements, T. A. Owen, Rita Bortell, Victoria Shalhoub, A Heinrichs, Janet L. Stein, Gary S. Stein, and Jane B. Lian

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ADA3: a gene, identified by resistance to GAL4-VP16, with properties similar to and different from those of ADA2, Benjamin Pina, Shelley L. Berger, Gregory A. Marcus, Neal S. Silverman, Julie Agapite, and Leonard Guarente

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Efficient double-strand break-stimulated recombination promoted by the general recombination systems of phages lambda and P22, Anthony R. Poteete and Anita C. Fenton

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Multiple copies of the bone-specific osteocalcin gene in mouse and rat, Shamim Rahman, Annette M. Oberdorf, Martin A. Montecino, Susan M. Tanhauser, Jane B. Lian, Gary S. Stein, Philip J. Laipis, and Janet L. Stein

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A switch in translation mediated by an antisense RNA, Koustubh Ranade and Anthony R. Poteete

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Effect of triphenyl tetrazolium chloride staining on the distribution of radiolabeled pharmaceuticals, Christopher P. Reinhardt, Howard Weinstein, John Wironen, and Jeffrey A. Leppo

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Specific, temporally regulated expression of the insulin-like growth factor II gene during muscle cell differentiation, Kenneth M. Rosen, Bruce Martin Wentworth, Nadia Rosenthal, and Lydia Villa-Komaroff

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Dengue virus protein recognition by virus-specific murine CD8+ cytotoxic T lymphocytes, Alan L. Rothman, Ichiro Kurane, Ching-Juh Lai, Michael Bray, Barry Falgout, Ruhe Men, and Francis A. Ennis

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Structural requirements of iodothyronines for the rapid inactivation and internalization of type II iodothyronine 5'-deiodinase in glial cells, Marjorie Safran, Alan P. Farwell, Hartmut Rokos, and Jack L. Leonard

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A Chlamydomonas outer arm dynein mutant with a truncated beta heavy chain, Hitoshi Sakakibara, Saeko Takada, Stephen M. King, George B. Witman, and Ritsu Kamiya (The Journal of cell biology)

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Mitogen-activated protein kinase stimulation by a tyrosine kinase-negative epidermal growth factor receptor, Erica Marie Selva, David L. Raden, and Roger J. Davis

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Cell cycle regulation of the c-Myc transcriptional activation domain, Alpna Seth, Shashi Gupta, and Roger J. Davis

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Regulation of alpha 6 beta 1 integrin laminin receptor function by the cytoplasmic domain of the alpha 6 subunit, Leslie M. Shaw and Arthur M. Mercurio

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Sequences in the 3'-untranslated region of the human cellular glutathione peroxidase gene are necessary and sufficient for selenocysteine incorporation at the UGA codon, Qichang Shen, Fong-Fong Chu, and Peter E. Newburger

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HIV risk among Latino adolescents in two New England cities, K. W. Smith, S. A. McGraw, Sybil L. Crawford, L. A. Costa, and J. B. McKinlay

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Health effects of gasoline exposure. I. Exposure assessment for U.S. distribution workers, Thomas J. Smith, S. Katharine Hammond, and Otto Wong

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Molecular basis for heme-dependent induction of heme oxygenase in primary cultures of chick embryo hepatocytes. Demonstration of acquired refractoriness to heme, Kishore K. Srivastava, Edward Earl Cable, Susan E. Donohue, and Herbert L. Bonkovsky

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Molecular mechanisms mediating proliferation/differentiation interrelationships during progressive development of the osteoblast phenotype, Gary S. Stein and Jane B. Lian

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Selective inhibition of antigen-specific T lymphocyte proliferation by acute ethanol exposure: the role of impaired monocyte antigen presentation capacity and mediator production, Gyongyi Szabo, Bikash K. Verma, and Donna Catalano

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High stimulatory activity of dendritic cells from diabetes-prone BioBreeding/Worcester rats exposed to macrophage-derived factors, Anna Tafuri, William E. Bowers, Eugene S. Handler, Michael C. Appel, Robert A. Lew, Dale L. Greiner, John P. Mordes, and Aldo A. Rossini

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Induction of renal adenocarcinoma by a nonmutated erbB oncogene, Cherie A. Taglienti, Barbara F. Banner, Roger J. Davis, and Harriet L. Robinson

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Concerted control of multiple histone promoter factors during cell density inhibition of proliferation in osteosarcoma cells: reciprocal regulation of cell cycle-controlled and bone-related genes, Fusinita M. I. van den Ent, Andre J. Van Wijnen, Thomas J. Last, Rita Bortell, Janet L. Stein, Jane B. Lian, and Gary S. Stein

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Favored and suppressed patterns of hydrophobic and nonhydrophobic amino acids in protein sequences, Stephen R. Vazquez, C Thomas, Robert A. Lew, and Robert E. Humphreys

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Measuring patients' views: the optimum outcome measure, John E. Ware Jr.

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Effect of a community health center intervention on breast cancer screening among Hispanic American women, Jane G. Zapka, Donald R. Harris, David W. Hosmer, Mary E. Costanza, Edith Mas, and Robin S. Barth

Publications from 1992

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The subcellular localization of the G-protein Gi alpha in the basal ganglia reveals its potential role in both signal transduction and vesicle trafficking, Neil Aronin and Marian DiFiglia

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Catalysis of serine and tyrosine autophosphorylation by the human insulin receptor, Kurt Baltensperger, Robert E. Lewis, Chee-Wai Woon, Prabhakar Vissavajjhala, Alonzo H. Ross, and Michael P. Czech

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Anti-CD2 monoclonal antibodies prevent spontaneous and adoptive transfer of diabetes in the BB/Wor rat, Avlin K. Barlow and Arthur A. Like

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ST segment depression in right-sided electrocardiographic leads in patients with acute myocardial infarction, A. Jauws Bradley and Joel M. Gore

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Recombinant human thyrotropin stimulates thyroid function and radioactive iodine uptake in the rhesus monkey, Lewis E. Braverman, Bruce M. Pratt, Susana A. Ebner, and Christopher Longcope

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The low risk of hepatitis C virus transmission among sexual partners of hepatitis C-infected hemophilic males: an international, multicenter study, Doreen B. Brettler, Pier Mannuccio Mannucci, Alessandro Gringeri, John E. J. Rasko, Ann D. Forsberg, Maria Grazia Rumi, Roger J. Garsia, Kathleen A. Rickard, and Massimo Colombo

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Silent human immunodeficiency virus type 1 infection: a rare occurrence in a high-risk heterosexual population, Doreen B. Brettler, Mohan Somasundaran, A. F. Forsberg, E. Krause, and John L. Sullivan

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Role of transthyretin in the transport of thyroxine from the blood to the choroid plexus, the cerebrospinal fluid, and the brain, Jean-Pierre Chanoine, Sharon Alex, Shih-Lieh Fang, Scott Stone, Jack L. Leonard, J. Korhle, and Lewis E. Braverman

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Effects of selenium deficiency on thyroid hormone economy in rats, Jean-Pierre Chanoine, Marjorie Safran, Alan P. Farwell, Susan A. Dubord-Tomasetti, Sharon Alex, Scott Stone, John R. Arthur, Lewis E. Braverman, and Jack L. Leonard

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Selenium deficiency and type II 5'-deiodinase regulation in the euthyroid and hypothyroid rat: evidence of a direct effect of thyroxine, Jean-Pierre Chanoine, Marjorie Safran, Alan P. Farwell, M. Patricia Tranter, Deborah M. Ekenbarger, Susan A. Dubord-Tomasetti, Sharon Alex, John R. Arthur, Geoffrey J. Beckett, and Lewis E. Braverman

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Translocation of ATP into the lumen of rough endoplasmic reticulum-derived vesicles and its binding to luminal proteins including BiP (GRP 78) and GRP 94, Caroline A. Clairmont, Antonio De Maio, and Carlos B. Hirschberg

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Impact of a physician intervention program to increase breast cancer screening, Mary E. Costanza, Jane G. Zapka, Donald R. Harris, David W. Hosmer, Robin S. Barth, Victoria P. Gaw, Harry L. Greene, and Anne M. Stoddard

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CT and MR evaluation of the labral capsular ligamentous complex of the shoulder, James M. Coumas, Richard J. Waite, Thomas P. Goss, Dudley A. Ferrari, Paulomi K. Kanzaria, and Arthur M. Pappas

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Mechanism of desensitization of the epidermal growth factor receptor protein-tyrosine kinase, Janice L. Countaway, Angus C. Nairn, and Roger J. Davis

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Planar myocardial perfusion imaging with technetium-99m-teboroxime: comparison by vascular territory with thallium-201 and coronary angiography, Seth T. Dahlberg, Howard Weinstein, Robert C. Hendel, Brenda A. McSherry, and Jeffrey A. Leppo

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Mutation of human immunodeficiency virus type 1 at amino acid 585 on gp41 results in loss of killing by CD8+ A24-restricted cytotoxic T lymphocytes, Li Chen Dai, Kim West, Rebecca A. Littaua, Kazuo Takahashi, and Francis A. Ennis

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Estradiol increases prolactin synthesis and prolactin messenger ribonucleic acid in selected brain regions in the hypophysectomized female rat, William J. DeVito, Crystal Avakian, Scott Stone, and Christopher I. Ace

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Effect of in vivo administration of recombinant acidic fibroblast growth factor on thyroid function in the rat: induction of colloid goiter, William J. DeVito, Jean-Pierre Chanoine, Sharon Alex, Shih-Lieh Fang, Scott Stone, Chris A. Huber, Victoria Shalhoub, Jane B. Lian, Gary S. Stein, and Lewis E. Braverman

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Prolactin-stimulated mitogenesis of cultured astrocytes, William J. DeVito, William C. Okulicz, Scott Stone, and Crystal Avakian

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The Tobacco Institute's "It's the Law" campaign: has it halted illegal sales of tobacco to children, Joseph R. DiFranza and Linda J. Brown

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In vitro susceptibility testing of Haemophilus influenzae: review of new National Committee for Clinical Laboratory Standards recommendations, Gary V. Doern

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Optimum use of selective plated media in primary processing of respiratory tract specimens from patients with cystic fibrosis, Gary V. Doern and Brenda B. Torres

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Reading and decision aids for improved accuracy and standardization of mammographic diagnosis, Carl J. D'Orsi, David J. Getty, John A. Swets, Ronald M. Pickett, Steven E. Seltzer, and Barbara J. McNeil

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Is calcium oxalate an adequate explanation for nonvisualization of breast specimen calcifications, Carl J. D'Orsi, Frank R. Reale, Michael A. Davis, and Vanessa J. Brown

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Small B cells as antigen-presenting cells in the induction of tolerance to soluble protein antigens, Elizabeth E. Eynon and David C. Parker