Open Access is free, unrestricted, online access to scientific and scholarly research. This collection includes Open Access journal articles and other materials authored by researchers, faculty, staff, and students at UMass Chan Medical School.

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Publications from 1998

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Evaluation of the Galalpha1-3Gal epitope as a host modification factor eliciting natural humoral immunity to enveloped viruses, Raymond M. Welsh, Carey L. O'Donnell, Deborah J. Reed, and Russell P. Rother

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Controlling gene expression in living cells through small molecule-RNA interactions, Geoffrey Werstuck and Michael R. Green

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Inhibition of chromosomal separation provides insights into cleavage furrow stimulation in cultured epithelial cells, Sally P. Wheatley, Christopher B. O'Connell, and Yu-Li Wang

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A mammalian scaffold complex that selectively mediates MAP kinase activation, Alan J. Whitmarsh, Julie Cavanagh, Cathy Tournier, Jun Yasuda, and Roger J. Davis

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Patterns of smoking, risk factors for smoking, and smoking cessation among Vietnamese men in Massachusetts (United States), John M. Wiecha, Vanna Lee, and Jane Hodgkins

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Crystal structure of the catalytic domain of protein-tyrosine phosphatase SHP-1, Jian Yang, Xiaoshan Liang, Tian-Qi Niu, Wuyi Meng, Zhizhuang Joe Zhao, and G. Wayne Zhou

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Behavioral and neurobiological consequences of social subjugation during puberty in golden hamsters, Delville Yvon, Richard H. Melloni, and Craig F. Ferris

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Ca2+ sparks activate K+ and Cl- channels, resulting in spontaneous transient currents in guinea-pig tracheal myocytes, Ronghua ZhuGe, Stephen M. Sims, Richard A. Tuft, Kevin E. Fogarty, and John V. Walsh

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High affinity Ca2+ binding sites of calmodulin are critical for the regulation of myosin Ibeta motor function, Tong Zhu, Kathleen M. Beckingham, and Mitsuo Ikebe

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A single amino acid substitution in yeast eIF-5A results in mRNA stabilization, Dorit Zuk and Allan Jacobson

Publications from 1997

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Glycine N-methyltransferase is an example of functional diversity. Role as a polycyclic aromatic hydrocarbon-binding receptor, Rashid Bhat and Edward Bresnick

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In vitro activity of BAY 12-8039, a novel 8-methoxyquinolone, compared to activities of six fluoroquinolones against Streptococcus pneumoniae, Haemophilus influenzae, and Moraxella catarrhalis, A B Brueggemann, K C Kugler, and Gary V. Doern

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The yeast SWI-SNF complex facilitates binding of a transcriptional activator to nucleosomal sites in vivo, Loree Griffin Burns and Craig L. Peterson

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Early results in the irrational design of new bifunctional chelators, F. Chang, Mary Rusckowski, Timothy Qu, and Donald J. Hnatowich

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Expression of methylthioadenosine phosphorylase cDNA in p16-, MTAP- malignant cells: restoration of methylthioadenosine phosphorylase-dependent salvage pathways and alterations of sensitivity to inhibitors of purine de novo synthesis, Zhi-Hao Chen, Olufunmilayo I. Olopade, and Todd M. Savarese

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Nuclear accumulation of NFAT4 opposed by the JNK signal transduction pathway, Chi-Wing Chow, Mercedes Rincon, Julie Cavanagh, Martin Dickens, and Roger J. Davis

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Expression of the Id family helix-loop-helix regulators during growth and development in the hematopoietic system, Cathleen L. Cooper, Gerard Brady, Fillio Bilia, Norman N. Iscove, and Peter J. Quesenberry

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Weight loss in people with Alzheimer's disease: a prospective population based analysis., Diane Cronin-Stubbs, Laurel A. Beckett, Paul A. Scherr, Terry S. Field, Marilyn J. Chown, David M. Pilgrim, David A. Bennett, and Denis A. Evans

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Effect of zinc concentration in Mueller-Hinton agar on susceptibility of Pseudomonas aeruginosa to imipenem, Jennifer S. Daly, Rosemary A. Dodge, Richard H. Glew, Don T. Soja, Barbara A. Deluca, and Susan R. Hebert

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The Mos pathway regulates cytoplasmic polyadenylation in Xenopus oocytes, Cornelia H. de Moor and Joel D. Richter

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Low concentrations of ethanol inhibits prolactin-induced mitogenesis and cytokine expression in cultured astrocytes, William J. DeVito, Scott Stone, and Kouki Mori

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Antibiotic resistance among clinical isolates of Haemophilus influenzae in the United States in 1994 and 1995 and detection of beta-lactamase-positive strains resistant to amoxicillin-clavulanate: results of a national multicenter surveillance study, Gary V. Doern, A B Brueggemann, G Pierce, H P Jr Holley, and A Rauch

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Four-day incubation period for blood culture bottles processed with the Difco ESP blood culture system, Gary V. Doern, Angela B. Brueggemann, W. Michael Dunne, Stephen G. Jenkins, Diane C. Halstead, and James C. McLaughlin

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Multicenter laboratory evaluation of the bioMerieux Vitek antimicrobial susceptibility testing system with 11 antimicrobial agents versus members of the family Enterobacteriaceae and Pseudomonas aeruginosa, Gary V. Doern, Angela B. Brueggemann, Rocco J. Perla, Jennifer S. Daly, Demetrios Halkias, Ronald N. Jones, and Michael A. Saubolle

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Vasopressin/serotonin interactions in the anterior hypothalamus control aggressive behavior in golden hamsters, Craig F. Ferris, Richard H. Melloni, Gary A. Koppel, Kenneth W. Perry, Ray W. Fuller, and Delville Yvon

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Goosecoid and HNF-3beta genetically interact to regulate neural tube patterning during mouse embryogenesis, Stefania Filosa, Jaime A. Rivera-Pérez, Aitana Perea Gomez, Anne Gansmuller, Hitoshi Sasaki, Richard R. Behringer, and Siew-Lan Ang (Development (Cambridge, England))

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U2AF65 recruits a novel human DEAD box protein required for the U2 snRNP-branchpoint interaction, Jan Fleckner, Meng Zhang, Juan Valcarcel, and Michael R. Green

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Effect of erionite on the pleural mesothelium of the Fischer 344 rat, Armando E. Fraire, S. Donald Greenberg, Harlan J. Spjut, Ronald F. Dodson, Glenn Williams, Ella Lach-Pasko, and Victor L. Roggli

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Activity of the osteocalcin promoter in skeletal sites of transgenic mice and during osteoblast differentiation in bone marrow-derived stromal cell cultures: effects of age and sex, Baruch Frenkel, Casey Capparelli, Moira Van Auken, Daniel T. Baran, J. Bryan, Janet L. Stein, Gary S. Stein, and Jane B. Lian

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Increased monocyte TNF-alpha message stability contributes to trauma patients' increased TNF production, Robert K. Furse, Karen Kodys, Dan Zhu, and Carol L. Miller-Graziano

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Functional group substitutions of the branchpoint adenosine in a nuclear pre-mRNA and a group II intron, Rajesh K. Gaur, Larry W. McLaughlin, and Michael R. Green

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Upf1p, Nmd2p, and Upf3p are interacting components of the yeast nonsense-mediated mRNA decay pathway, Feng He, Agneta H. Brown, and Allan Jacobson

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Differential regulation of gastrulation and neuroectodermal gene expression by Snail in the Drosophila embryo, Kirugaval Hemavathy, Xiangjun Meng, and Y. Tony Ip

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The G beta gamma complex of the yeast pheromone response pathway. Subcellular fractionation and protein-protein interactions, Jodi E. Hirschman, Gerard S. De Zutter, William F. Simonds, and Duane D. Jenness

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ADA1, a novel component of the ADA/GCN5 complex, has broader effects than GCN5, ADA2, or ADA3, Junjiro Horiuchi, Neal S. Silverman, Benjamin Pina, Gregory A. Marcus, and Leonard Guarente

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Elimination of defective alpha-factor pheromone receptors, Duane D. Jenness, Yu Li, Christopher Tipper, and Phyllis Spatrick

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DAD1, the defender against apoptotic cell death, is a subunit of the mammalian oligosaccharyltransferase, Daniel J. Kelleher and Reid Gilmore

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beta-Actin messenger RNA localization and protein synthesis augment cell motility, Edward H. Kislauskis, Xiaochun Zhu, and Robert H. Singer

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Cytokine-facilitated transduction leads to low-level engraftment in nonablated hosts, Ellen L. W. Kittler, Stefan O. Peters, Rowena B. Crittenden, Michelle E. Debatis, Hayley S. Ramshaw, F. Marc Stewart, and Peter J. Quesenberry

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Signaling by phosphoinositide-3,4,5-trisphosphate through proteins containing pleckstrin and Sec7 homology domains, Jes K. Klarlund, Adilson L. Guilherme, John Holik, Joseph V. Virbasius, Anil Chawla, and Michael P. Czech

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Bilateral anaerobic empyemas complicating infectious mononucleosis, Scott E. Kopec, Richard S. Irwin, Curtis J. Mello, and Cynthia B. Umali

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The Chlamydomonas reinhardtii ODA3 gene encodes a protein of the outer dynein arm docking complex, Anthony Koutoulis, Gregory J. Pazour, Curtis G. Wilkerson, Kazuo Inaba, Hong Sheng, Saeko Takada, and George B. Witman (The Journal of cell biology)

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TrkA expression decreases the in vivo aggressiveness of C6 glioma cells, Mahesh B. Lachyankar, Alonzo H. Ross, N. Scott Litofsky, Peter J. Condon, Peter J. Quesenberry, and Lawrence D. Recht

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The RNA polymerase alpha subunit carboxyl-terminal domain is required for both basal and activated transcription from the alkA promoter, Paolo Landini, Tamas Gaal, Wilma Ross, and Michael R. Volkert

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Species-specific glucocorticoid and 1,25-dihydroxyvitamin D responsiveness in mouse MC3T3-E1 osteoblasts: dexamethasone inhibits osteoblast differentiation and vitamin D down-regulates osteocalcin gene expression, Jane B. Lian, Victoria Shalhoub, Fauzia Aslam, Baruch Frenkel, Jack Green, Michael Hamrah, Gary S. Stein, and Janet L. Stein

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RAC3, a steroid/nuclear receptor-associated coactivator that is related to SRC-1 and TIF2, Hui Li, Paulo J. Gomes, and J. Don Chen

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Fpg protein releases a ring-opened N-7 guanine adduct from DNA that has been modified by sulfur mustard, Qiong Li, Jacques Laval, and David B. Ludlum

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Combination treatment with zidovudine, didanosine, and nevirapine in infants with human immunodeficiency virus type 1 infection, Katherine Luzuriaga, Yvonne J. Bryson, Paul A. Krogstad, James E. Robinson, Barbara Stechenberg, Michael Lamson, Susannah Cort, and John L. Sullivan

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Slow cycling of unphosphorylated myosin is inhibited by calponin, thus keeping smooth muscle relaxed, Ulf P. Malmqvist, Kathleen M. Trybus, Shinobu Yagi, Jeffrey Carmichael, and Fredric S. Fay

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Disulfide bond formation is a determinant of glycosylation site usage in the hemagglutinin-neuraminidase glycoprotein of Newcastle disease virus, Lori McGinnes and Trudy G. Morrison

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Interactions of Drosophila Cbl with epidermal growth factor receptors and role of Cbl in R7 photoreceptor cell development, Herman Meisner, Andrea Daga, Joanne M. Buxton, Belen Fernandez, Anil Chawla, Utpal Banerjee, and Michael P. Czech

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Dde-I restriction endonuclease fragmentation: a novel method of generating cDNA probes for in situ hybridization in brain, Richard H. Melloni, Neil Aronin, Louis J. DeGennaro, Craig F. Ferris, and Robert J. Harrison

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Instability of CAG and CTG trinucleotide repeats in Saccharomyces cerevisiae, Juan J. Miret, Luis Pessoa-Brandao, and Robert S. Lahue

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Cytokine production by dengue virus antigen-responsive human T lymphocytes in vitro examined using a double immunocytochemical technique, Masuko Mori, Ichiro Kurane, Jurand Janus, and Francis A. Ennis

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The nuclear matrix revealed by eluting chromatin from a cross-linked nucleus, Jeffrey A. Nickerson, Gabriela Krockmalnic, Katherine M. Wan, and Sheldon Penman

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Potential and distribution of transplanted hematopoietic stem cells in a nonablated mouse model, Susan K. Nilsson, Mark S. Dooner, Candi Y. Tiarks, Heinz-Ulrich Weier, and Peter J. Quesenberry

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Fractures of the hands and feet in child abuse: imaging and pathologic features, Katherine Nimkin, Melissa R. Spevak, and Paul K. Kleinman

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Necrotizing tracheobronchitis with progressive airflow obstruction associated with paraneoplastic pemphigus, James P. Osmanski II, Armando E. Fraire, and Oren P. Schaefer

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Identification of an early endosomal protein regulated by phosphatidylinositol 3-kinase, Varsha Patki, Joseph V. Virbasius, William S. Lane, Ban-Hock Toh, Howard S. Shpetner, and Silvia Corvera

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Mitochondrial association of a plus end-directed microtubule motor expressed during mitosis in Drosophila, Andrea J. Pereira, Brian Dalby, Russell J. Stewart, Stephen J. Doxsey, and Lawrence S. B. Goldstein

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Early HIV-1 envelope-specific cytotoxic T lymphocyte responses in vertically infected infants, Cheryl A. Pikora, John L. Sullivan, Dennis Panicali, and Katherine Luzuriaga

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Role for ADA/GCN5 products in antagonizing chromatin-mediated transcriptional repression, Kerri Jeanne Pollard and Craig L. Peterson

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Evaluation of right and left ventricular volume and ejection fraction using a mathematical cardiac torso phantom, P. Hendrik Pretorius, Weishi Xia, Michael A. King, Benjamin M. W. Tsui, Tin-Su Pan, and Bernard J. Villegas

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Recombinant human thyrotropin is a potent stimulator of thyroid function in normal subjects, Luis Ramirez, Lewis E. Braverman, Bernadette M. White, and Charles H. Emerson

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Cell cycle analysis and synchronization of pluripotent hematopoietic progenitor stem cells, G. Prem Veer Reddy, Cheryl Y. Tiarks, Lizhen Pang, Joanne Wuu, Chung-Cheng Hsieh, and Peter J. Quesenberry

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Critical uses of intraoperative gynecologic sonography, Karen L. Reuter

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Optimising drug treatment for elderly people: the prescribing cascade., Paula A. Rochon and Jerry H. Gurwitz

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Characterization of a beta-actin mRNA zipcode-binding protein, Anthony F. Ross, Yuri Oleynikov, Edward H. Kislauskis, Krishan L. Taneja, and Robert H. Singer

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Oral administration of unsaturated fatty acids: effects on human peripheral blood T lymphocyte proliferation, Ronald G. Rossetti, Christina M. Seiler, Pamela DeLuca, Michael Laposata, and Robert Zurier

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Ligand linked assembly of Scapharca dimeric hemoglobin, William E. Royer Jr., Rachael A. Fox, Francine R. Smith, Dan Zhu, and Emory H. Braswell

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Pretargeting with Amplification Using Polymeric Peptide Nucleic Acid, Mary Rusckowski, Timothy Qu, F. Chang, and Donald J. Hnatowich

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Systolic function in hypertensive men with concentric remodeling, Diego B. Sadler, Gerard P. Aurigemma, David W. Williams, Domenic J. Reda, Barry J. Materson, and John S. Gottdiener

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Nonlinear systems identification: autocorrelation vs. autoskewness, Michel Sammon and Frederick J. Curley

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The motor domain and the regulatory domain of myosin solely dictate enzymatic activity and phosphorylation-dependent regulation, respectively, Masataka Sata, Walter F. Stafford, Katsuhide Mabuchi, and Mitsuo Ikebe

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A kindred with a variant of multiple endocrine neoplasia type 1 demonstrating frequent expression of pituitary tumors but not linked to the multiple endocrine neoplasia type 1 locus at chromosome region 11q13, John L. Stock, Maria R. Warth, Bin Tean Teh, James A. Coderre, Judith H. Overdorf, Gerhard Baumann, Raymond L. Hintz, Mark L. Hartman, Bernd R. Seizinger, Catharina Larsson, and Neil Aronin

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Detection of an interaction between the HN and F proteins in Newcastle disease virus-infected cells, Judith Stone-Hulslander and Trudy G. Morrison

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Caretaker Obstreperous Behavior Rating Scale, Joan M. Swearer and David A. Drachman

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Mitogen-activated protein kinase kinase 7 is an activator of the c-Jun NH2-terminal kinase, Cathy Tournier, Alan J. Whitmarsh, Julie Cavanagh, Tamera Barrett, and Roger J. Davis

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An ATP-gated cation channel with some P2Z-like characteristics in gastric smooth muscle cells of toad, Mehmet Ugur, Robert M. Drummond, Hui Zou, Peihua Sheng, Joshua J. Singer, and John V. Walsh

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c-Myc/Max heterodimers bind cooperatively to the E-box sequences located in the first intron of the rat ornithine decarboxylase (ODC) gene, Albertha J. M. Walhout, J. M. Gubbels, R. Bernards, P. C. van der Vliet, and H. Th. M. Timmers

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Effects of Sin- versions of histone H4 on yeast chromatin structure and function, Mark A. Wechser, Michael P. Kladde, Jennifer A. Alfieri, and Craig L. Peterson

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The 1996 Bigelow Award of the Boston Surgical Society: Henry Jacob Bigelow and David C. Sabiston, Jr, H. Brownell Wheeler

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Role of p38 and JNK mitogen-activated protein kinases in the activation of ternary complex factors, Alan J. Whitmarsh, Shen-Hsi Yang, Michael S. S. Su, Andrew D. Sharrocks, and Roger J. Davis

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The 36-kilodalton embryonic-type cytoplasmic polyadenylation element-binding protein in Xenopus laevis is ElrA, a member of the ELAV family of RNA-binding proteins, Lin Wu, Peter J. Good, and Joel D. Richter

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Identification of a human protein that recognizes the 3' splice site during the second step of pre-mRNA splicing, Shaoping Wu and Michael R. Green

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Synthesis and effect of nonhydrolyzable xanthosine triphosphate derivatives on prenylation of Rab5D136N, Ivan Yanachkov, Julie Y. Pan, Marianne Wessling-Resnick, and George E. Wright

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Minimal bystander activation of CD8 T cells during the virus-induced polyclonal T cell response, Christopher C. Zarozinski and Raymond M. Welsh

Publications from 1996

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A mutant yeast deficient in Golgi transport of uridine diphosphate N-acetylglucosamine, Claudia Abeijon, Elisabet C. Mandon, Phillips W. Robbins, and Carlos B. Hirschberg

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Molecular cloning of the Golgi apparatus uridine diphosphate-N-acetylglucosamine transporter from Kluyveromyces lactis, Claudia Abeijon, Phillips W. Robbins, and Carlos B. Hirschberg

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Yeast TAF(II)90 is required for cell-cycle progression through G2/M but not for general transcription activation, Lynne Marie Apone, Ching-man A. Virbasius, Joseph C. Reese, and Michael R. Green

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Dominant negative mutator mutations in the mutL gene of Escherichia coli, Alexander Aronshtam and Martin G. Marinus

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The beta-adrenergic receptor is a substrate for the insulin receptor tyrosine kinase, Kurt Baltensperger, Vijaya Karoor, Hyacinth Paul, Arnold E. Ruoho, Michael P. Czech, and Craig C. Malbon

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Transforming growth factor-beta 1 responsiveness of the rat osteocalcin gene is mediated by an activator protein-1 binding site, Chaitali Banerjee, Janet L. Stein, Andre J. Van Wijnen, Baruch Frenkel, Jane B. Lian, and Gary S. Stein

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Laminin promotes differentiation of NB4 promyelocytic leukemia cells with all-trans retinoic acid, Pamela S. Becker, Zhifang Li, Tamara Potselueva, Joseph A. Madri, Peter E. Newburger, and Nancy Berliner

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ATP depletion affects the phosphorylation state, ligand binding, and nuclear transport of the 4 S polycyclic aromatic hydrocarbon-binding protein in rat hepatoma cells, Rashid Bhat, James A. Weaver, Conrad Wagner, Jack E. Bodwell, and Edward Bresnick

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Second-site reversion of a structural defect in bacteriophage T4 lysozyme, Suzanne E. Bouvier and Anthony R. Poteete

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Incidence of transient congenital hypothyroidism due to maternal thyrotropin receptor-blocking antibodies in over one million babies, Rosalind S. Brown, Ronald L. Bellisario, Diego Botero, Lawrence Fournier, Cyril A. L. Abrams, Marilyn L. Cowger, Ralph David, Pavel Fort, and Robert A. Richman

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Agonist-specific conformational changes in the yeast alpha-factor pheromone receptor, Gul Bukusoglu and Duane D. Jenness

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Hepatic 5-aminolevulinic acid synthase mRNA stability is modulated by inhibitors of heme biosynthesis and by metalloporphyrins, Edward Earl Cable, Otto S. Gildemeister, Joyce A. Pepe, Susan E. Donohue, Richard W. Lambrecht, and Herbert L. Bonkovsky

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Gene deletion chemoselectivity: codeletion of the genes for p16(INK4), methylthioadenosine phosphorylase, and the alpha- and beta-interferons in human pancreatic cell carcinoma lines and its implications for chemotherapy, Zhi-Hao Chen, Hongyang Zhang, and Todd M. Savarese