Open Access is free, unrestricted, online access to scientific and scholarly research. This collection includes Open Access journal articles and other materials authored by researchers, faculty, staff, and students at UMass Chan Medical School.

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Publications from 2021

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Editorial: Immunology of Vitiligo, Julien Seneschal, John E. Harris, I. Caroline Le Poole, Thierry Passeron, Reinhart Speeckaert, and Katia Boniface

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Do Fragile X Syndrome and Other Intellectual Disorders Converge at Aberrant Pre-mRNA Splicing, Sneha Shah and Joel D. Richter

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Study Design and Data Analysis of Artificial Pancreas Device Systems with Closed-Loop Glucose-Sensing Insulin Delivery, Sravya B. Shankara, Yujia Liu, Qingfeng Zheng, Jing Guo, Guixia Wang, and Bo Zhang

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Mechanism of LolCDE as a molecular extruder of bacterial triacylated lipoproteins, Stuti Sharma, Ruoyu Zhou, Li Wan, Shan Feng, KangKang Song, Chen Xu, Yanyan Li, and Maofu Liao

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The Bromodomains of the mammalian SWI/SNF (mSWI/SNF) ATPases Brahma (BRM) and Brahma Related Gene 1 (BRG1) promote chromatin interaction and are critical for skeletal muscle differentiation, Tapan Sharma, Daniel C. L. Robinson, Hanna Witwicka, F. Jeffrey Dilworth, and Anthony N. Imbalzano

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TBK1 has a new Akt, Leslie M. Shaw

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The Emerging Global Tobacco Treatment Workforce: Characteristics of Tobacco Treatment Specialists Trained in Council-Accredited Training Programs from 2017 to 2019, Christine E. Sheffer and Caroline Cranos

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Sirtuin 3 Downregulation in Mycobacterium tuberculosis-Infected Macrophages Reprograms Mitochondrial Metabolism and Promotes Cell Death, Lorissa J. Smulan, Nuria M. Martinez, Michael C. Kiritsy, Chido L. Kativhu, Kelly Cavallo, Christopher M. Sassetti, Amit Singhal, Heinz G. Remold, and Hardy Kornfeld

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Endoplasmic Reticulum Stress Induced Proliferation Remains Intact in Aging Mouse beta-Cells, Jarin T. Snyder, Christine Darko, Rohit B. Sharma, and Laura C. Alonso

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Early childhood undernutrition, preadolescent physical growth, and cognitive achievement in India: A population-based cohort study, Apurv Soni, Nisha Fahey, Zulfiqar A. Bhutta, Wenjun Li, Jean A. Frazier, Tiffany A. Moore Simas, Somashekhar M. Nimbalkar, and Jeroan J. Allison

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Single-cell RNA-seq reveals transcriptomic heterogeneity mediated by host-pathogen dynamics in lymphoblastoid cell lines, Elliott D. SoRelle, Joanne Dai, Emmanuela N. Bonglack, Emma M. Heckenberg, Jeffrey Y. Zhou, Stephanie N. Giamberardino, Jeffrey A. Bailey, Simon G. Gregory, Cliburn Chan, and Micah A. Luftig

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Yeast Particle Encapsulation of Scaffolded Terpene Compounds for Controlled Terpene Release, Ernesto R. Soto, Florentina Rus, Hanchen Li, Carli Garceau, Jeffrey Chicca, Elfawal A. Mostafa, David Gazzola, Martin K. Nielsen, Joseph F. Urban Jr., Raffi V. Aroian, and Gary R. Ostroff

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NLRC4 inhibits NLRP3 inflammasome and abrogates effective antifungal CD8(+) T cell responses, Camila O. S. Souza, Natalia Ketelut-Carneiro, Cristiane M. Milanezi, Lucia H. Faccioli, Luiz G. Gardinassi, and Joao S. Silva

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Nox4 mediates skeletal muscle metabolic responses to exercise, Kalyn S. Specht, Shashi Kant, Heather Learnard, Maura Campbell, Amada D. Caliz, Yongmei Pei, Michaella M. Reif, John F. Keaney Jr., and Siobhan M. Craige

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Changes in psychosocial functioning among urban, school-age children during the COVID-19 pandemic, Andrea E. Spencer, J. Michael Murphy, and Arvin Garg

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Germ granule dysfunction is a hallmark and mirror of Piwi mutant sterility, Maya Spichal, Bree Heestand, Katherine Kretovich Billmyre, Stephen Frenk, Craig C. Mello, and Shawn Ahmed

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Evaluation of the Acceptability of a Proposed, Instagram-Based, Randomized Controlled Trial for People With Asthma: Survey Study, Kerry A. Spitzer, Brent Heineman, Marcella Jewell, Michael Moran, and Peter Lindenauer

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A Plant-Produced Virus-Like Particle Displaying Envelope Protein Domain III Elicits an Immune Response Against West Nile Virus in Mice, Jennifer Stander, Aleyo Chabeda, Edward P. Rybicki, and Ann E. Meyers

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Sweet Syndrome, Not so Sweet during an Ulcerative Colitis Flare Especially When You Cannot Eat, Courtney Stead, Shahrad Hakimian, Christina Luffman, Zendee Elaba, Gregory Orlowski, and Neil B. Marya

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A budding yeast model for human disease mutations in the EXOSC2 cap subunit of the RNA exosome complex, Maria C. Sterrett, Liz Enyenihi, Sara W. Leung, Laurie Hess, Sarah E. Strassler, Daniela Farchi, Richard S. Lee, Elise S. Withers, Isaac Kremsky, Richard E. Baker, Munira A. Basrai, Ambro van Hoof, Milo B. Fasken, and Anita H. Corbett

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Unmet Medical Needs in the Treatment and Management of Generalized Pustular Psoriasis Flares: Evidence from a Survey of Corrona Registry Dermatologists, Bruce Strober, Nirali Kotowsky, Rose Medeiros, Rachel H. Mackey, Leslie R. Harrold, Wendell C. Valdecantos, Mary Flack, Amanda K. Golembesky, and Mark Lebwohl

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Prenatal Diethylstilbestrol Exposure and Cancer Risk in Males, William C. Strohsnitter, Marianne Hyer, Kimberly A. Bertrand, Andrea L. Cheville, Julie R. Palmer, Elizabeth E. Hatch, Kjersti M. Aagaard, Linda Titus, Iris L. Romero, Dezheng Huo, Robert N. Hoover, and Rebecca Troisi

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Transcutaneous carbon dioxide pattern and trend over time in preterm infants, Katherine P. Sullivan, Heather White, Lindsay E. Grover, Jordi J. Negron, Austin F. Lee, and Lawrence M. Rhein

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Onco-fertility and personalized testing for potential for loss of ovarian reserve in patients undergoing chemotherapy: proposed next steps for development of genetic testing to predict changes in ovarian reserve, Bei Sun and John Yeh

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SLITRK5 is a negative regulator of hedgehog signaling in osteoblasts, Jun Sun, Jae-Hyuck Shim, Ren Xu, and Matthew B. Greenblatt

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The Utility of MYB Immunohistochemistry (IHC) in Fine Needle Aspiration (FNA) Diagnosis of Adenoid Cystic Carcinoma (AdCC), Tong Sun, Ali Akalin, Karen A. Dresser, Andrew H. Fischer, and Tao Zuo

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Efficacious, safe, and stable inhibition of corneal neovascularization by AAV-vectored anti-VEGF therapeutics, Wenqi Su, Shuo Sun, Bo Tian, Phillip W. L. Tai, Yongwen Luo, Jihye Ko, Wei Zhan, Xiao Ke, Qiang Zheng, Xiaorong Li, Hua Yan, Guangping Gao, and Haijiang Lin

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Implementation of Patient Engagement Tools in Electronic Health Records to Enhance Patient-Centered Communication: Protocol for Feasibility Evaluation and Preliminary Results, Ming Tai-Seale, Rebecca Rosen, Bernice Ruo, Michael Hogarth, Christopher A. Longhurst, Lina Lander, Amanda L. Walker, Cheryl D. Stults, Albert Chan, Kathleen M. Mazor, Lawrence D. Garber, and Marlene Millen

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Sequencing of 53,831 diverse genomes from the NHLBI TOPMed Program, Daniel Taliun, David D. McManus, L. Adrienne Cupples, Cathy C. Laurie, Cashell E. Jaquish, Ryan D. Hernandez, Timothy D. O'Connor, and Goncalo R. Abecasis

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Digital Health Information Disparities in Older Adults: a Mixed Methods Study, Ruth M. Tappen, Mary E. Cooley, Roger Luckmann, and Somi Panday

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Investigation of a monoclonal antibody against enterotoxigenic Escherichia coli, expressed as secretory IgA1 and IgA2 in plants, Audrey Y-H. Teh, Lisa A. Cavacini, Yue Hu, Ozan S. Kumru, Jian Xiong, David T. Bolick, Sangeeta B. Joshi, Clemens Grunwald-Gruber, Friedrich Altmann, Mark S. Klempner, Richard L. Guerrant, David B. Volkin, Yang Wang, and Julian K-C. Ma

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Chromosome-Level Assembly of the Atlantic Silverside Genome Reveals Extreme Levels of Sequence Diversity and Structural Genetic Variation, Anna Tigano, Arne Jacobs, Aryn P. Wilder, Ankita Nand, Ye Zhan, Job Dekker, and Nina Overgaard Therkildsen

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Using increased trust in medical researchers to increase minority recruitment: The RECRUIT cluster randomized clinical trial, Barbara C. Tilley, Arch G. Mainous 3rd, Rossybelle P. Amorrortu, M. Diane McKee, Daniel W. Smith, Ruosha Li, Stacia M. DeSantis, Sally W. Vernon, Gary Koch, Marvella E. Ford, Vanessa Diaz, and Jennifer Alvidrez

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Diagnostic accuracy of cardiac testing for coronary artery disease in potential liver transplant recipients: A systematic review and meta-analysis, Nidhish Tiwari, Jyothi Margapuri, Adarsh Katamreddy, Sandeep Jubbal, and Nidhi Madan

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Stakeholder-engaged process for refining the design of a clinical trial in home hospice, Jennifer Tjia, Margaret Clayton, German Chiriboga, Brooke Staples, Geraldine Puerto, Lynley Rappaport, and Susan DeSanto-Madeya

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Cohesin mutations alter DNA damage repair and chromatin structure and create therapeutic vulnerabilities in MDS/AML, Zuzana Tothova, Anne-Laure Valton, Sergey V. Venev, Job Dekker, and Benjamin L. Ebert

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Impact of hepatitis C remission on glycemic control in patients with type 2 diabetes mellitus: primary care outpatient experience, Kartikeya Tripathi, Sundaravadivel Loganathan, Nitin Trivedi, and George Abraham

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Somatic piRNAs and Transposons are Differentially Expressed Coincident with Skeletal Muscle Atrophy and Programmed Cell Death, Junko Tsuji, Travis Thomson, Christine Brown, Subhanita Ghosh, William E. Theurkauf, Zhiping Weng, and Lawrence M. Schwartz

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Neuroligin-3: A Circuit-Specific Synapse Organizer That Shapes Normal Function and Autism Spectrum Disorder-Associated Dysfunction, Motokazu Uchigashima, Amy Cheung, and Kensuke Futai

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Start codon disruption with CRISPR/Cas9 prevents murine Fuchs' endothelial corneal dystrophy, Hironori Uehara, Guangping Gao, and Balamurali K. Ambati

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An inactivated bacterium (paraprobiotic) expressing Bacillus thuringiensis Cry5B as a therapeutic for Ascaris and Parascaris spp. infections in large animals, Joseph F. Urban Jr, Martin K. Nielsen, David Gazzola, Yue Xie, Ethiopia Beshah, Yan Hu, Hanchen Li, Florentina Rus, Kelly Flanagan, Austin Draper, Sridhar Vakalapudi, Robert W. Li, Gary R. Ostroff, and Raffi V. Aroian

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Annotation of chromatin states in 66 complete mouse epigenomes during development, Arjan van der Velde, Kaili Fan, Junko Tsuji, Jill E. Moore, Michael J. Purcaro, Henry E. Pratt, and Zhiping Weng

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Benign Tumors in Long-Term Survivors of Retinoblastoma, Milo van Hoefen Wijsard, Sara J. Schonfeld, Flora E. van Leeuwen, Annette C. Moll, Armida W. Fabius, David H. Abramson, Johanna M. Seddon, Jasmine H. Francis, Margaret A. Tucker, Ruth A. Kleinerman, and Lindsay M. Morton

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Histological assessment of developmental cell death in Drosophila pupae, Panagiotis D. Velentzas and Eric H. Baehrecke

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Using deep learning to identify bladder cancers with FGFR-activating mutations from histology images, Constantine S. Velmahos, Marcus Badgeley, and Ying-Chun Lo

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A 5-year clinical follow-up study from the Italian National Registry for FSHD, Liliana Vercelli, Louise Maranda, Tiziana Mongini, and Rossella Ginevra Tupler

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Constitutive immune activity promotes JNK- and FoxO-dependent remodeling of Drosophila airways, Christina Wagner, Neal S. Silverman, and Thomas Roeder

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Is this the end for ranitidine? NDMA presence continues to confound, Jennifer A. Wagner, Jean C. Dinh, Jenifer R. Lightdale, Benjamin D. Gold, and Jennifer M. Colombo

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WormPaths: Caenorhabditis elegans metabolic pathway annotation and visualization, Melissa D. Walker, Gabrielle E. Giese, Amy D. Holdorf, Sushila Bhattacharya, Cedric Diot, Aurian Garcia-Gonzalez, Brent Horowitz, Yong-Uk Lee, Thomas Leland, Xuhang Li, Zeynep Mirza, Huimin Na, Shivani Nanda, Olga Ponomarova, Hefei Zhang, Jingyan Zhang, L. Safak Yilmaz, and Albertha J. M. Walhout

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Development and Validation of an Automated Algorithm to Detect Atrial Fibrillation Within Stored Intensive Care Unit Continuous Electrocardiographic Data: Observational Study, Allan J. Walkey, Syed K. Bashar, Md Billal. Hossain, Eric Y. Ding, Daniella Albuquerque, Michael Winter, Ki H. Chon, and David D. McManus

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Pseudomonas aeruginosa PA14 produces R-bodies, extendable protein polymers with roles in host colonization and virulence, Bryan Wang, Yu-Cheng Lin, Alejandro Vasquez-Rifo, Jeanyoung Jo, Alexa Price-Whelan, Shujuan Tao McDonald, Lewis M. Brown, Christian Sieben, and Lars E.P. Dietrich

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Deficient spermiogenesis in mice lacking Rlim, Feng Wang, Maria Gracia Gervasi, Ana Boskovic, Fengyun Sun, Vera D. Rinaldi, Jun Yu, Mary C. Wallingford, Darya A. Tourzani, Jesse Mager, Lihua Julie Zhu, Oliver J. Rando, Pablo E. Visconti, Lara Strittmatter, and Ingolf Bach

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Common Polymorphisms in the Glycoproteins of Human Cytomegalovirus and Associated Strain-Specific Immunity, Hsuan-Yuan Wang, Sarah M. Valencia, Susanne P. Pfeifer, Jeffrey D. Jensen, Timothy F. Kowalik, and Sallie R. Permar

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A youth empowerment intervention to prevent childhood obesity: design and methods for a cluster randomized trial of the H2GO! program, Monica L. Wang, Linda S. Sprague Martinez, Janice Weinberg, Selenne Alatorre, Stephenie C. Lemon, and Milagros C. Rosal

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Role of epigenetics in unicellular to multicellular transition in Dictyostelium, Simon Yuan Wang, Elizabeth Ann Pollina, I-Hao Wang, Lindsay Kristina Pino, Henry L. Bushnell, Ken Takashima, Colette Fritsche, George Sabin, Benjamin Aaron. Garcia, Paul L. Greer, and Eric Lieberman Greer

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Adenocarcinoma of the Prostate: Future Directions for Translational Science, Tao Wang, Brian C. Lewis, Ameer L. Elaimy, Marcus Ruscetti, Mitchell H. Sokoloff, Kriti Mittal, and Thomas J. Fitzgerald

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Post-allogeneic hematopoietic stem cell transplantation viral reactivations and viremias: a focused review on human herpesvirus-6, BK virus and adenovirus, Xin Wang, Shyam A. Patel, Michael Haddadin, and Jan Cerny

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NHR-49/PPAR-alpha and HLH-30/TFEB cooperate for C. elegans host defense via a flavin-containing monooxygenase, Khursheed A. Wani, Debanjan Goswamy, Stefan Taubert, Ramesh Ratnappan, Arjumand Ghazi, and Javier E. Irazoqui

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Being Brave, Andrea L. Wendling, Valerie Gilchrist, Christy J. W. Ledford, Jennifer Lochner, Julie P. Phillips, Sara G. Shields, and Kirsten Winnie

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Upcoming treatments for morphea, Dan Wenzel, Nazgol-Sadat Haddadi, Khashayar Afshari, Jillian M. Richmond, and Medhi Rashighi

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Inadequate Cerebrospinal Fluid Concentrations of Available Salvage Agents Further Impedes the Optimal Treatment of Multidrug-Resistant Enterococcus faecium Meningitis and Bacteremia, Eric Wenzler, Alina Adeel, Tiffany Wu, Michele Jurkovic, Jeremy Walder, Emily Ramasra, Maureen Campion, Jan Cerny, and Nicole M. Theodoropoulos

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Filgotinib in combination with methotrexate or as monotherapy versus methotrexate monotherapy in patients with active rheumatoid arthritis and limited or no prior exposure to methotrexate: the phase 3, randomised controlled FINCH 3 trial, Rene Westhovens and Jonathan Kay

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Rpgrip1l controls ciliary gating by ensuring the proper amount of Cep290 at the vertebrate transition zone, Antonia Wiegering, Renate Dildrop, Christine Vesque, Hemant Khanna, Sylvie Schneider-Maunoury, and Christoph Gerhardt

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CYLD mutation characterizes a subset of HPV-positive head and neck squamous cell carcinomas with distinctive genomics and frequent cylindroma-like histologic features, Erik A. Williams, Meagan Montesion, Brian M. Alexander, Shakti H. Ramkissoon, Julia A. Elvin, Jeffrey S. Ross, Kevin Jon. Williams, Krzysztof Glomski, Jacob R. Bledsoe, Julie Y. Tse, and Mark C. Mochel

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Gastrointestinal microbiota composition predicts peripheral inflammatory state during treatment of human tuberculosis, Matthew F. Wipperman, Shakti K. Bhattarai, Charles Kyriakos Vorkas, Venkata Suhas Maringati, Ying Taur, Laurent Mathurin, Katherine McAulay, Stalz Charles Vilbrun, Daphie Francois, James Bean, Kathleen F. Walsh, Carl Nathan, Daniel W. Fitzgerald, Michael S. Glickman, and Vanni Bucci

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"I'm not gonna be able to do anything about it, then what's the point?": A broad group of stakeholders identify barriers and facilitators to HCV testing in a Massachusetts jail, Alysse G. Wurcel, Jessica Reyes, Julia Zubiago, Peter J. Koutoujian, Deirdre Burke, Tamsin A. Knox, Thomas Concannon, Stephenie C. Lemon, John B. Wong, Karen M. Freund, Curt G. Beckwith, and Amy M. LeClair

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Maternal 3,3'-Diiodothyronine Sulfate Formation from Guinea Pig Placenta Perfused with 3,3',5-Triodothyronine, Sing-Yung Wu, Charles H. Emerson, Edward Tjioe, and Dong-Bao Chen

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Down-regulation of the tumor suppressor miR-34a contributes to head and neck cancer by up-regulating the MET oncogene and modulating tumor immune evasion, Xun Wu, Yi-Shing Lisa Cheng, Mathew Matthen, Angela Yoon, Gary K. Schwartz, Shashi Bala, Alison M. Taylor, and Fatemeh Momen-Heravi

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Lung eosinophils elicited during allergic and acute aspergillosis express RORgammat and IL-23R but do not require IL-23 for IL-17 production, Bhawna Yadav, Charles A. Specht, Chrono K. Lee, Maria Pokrovskii, Jun R. Huh, Dan R. Littman, and Stuart M. Levitz

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Effect of Alteplase Use on Outcomes in Patients With Atrial Fibrillation: Analysis of the Initiation of Anticoagulation After Cardioembolic Stroke Study, Shadi Yaghi and Nils Henninger

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Minimally-invasive pain management techniques in palliative care, Bhavana Yalamuru, Jacqueline Weisbein, Amy C.S. Pearson, and Enas S. Kandil

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Increased plasmin-mediated proteolysis of L1CAM in a mouse model of idiopathic normal pressure hydrocephalus, Dejun Yang, Hong Wei. Yang, Gabrielle A. Luiselli, Charles Ogagan, Huijun Dai, Lucinda Chiu, Rona S. Carroll, and Mark D. Johnson

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A therapeutic convection-enhanced macroencapsulation device for enhancing beta cell viability and insulin secretion, Kisuk Yang, Dale L. Greiner, and Jeffrey M. Karp

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Rapid inactivation of the yeast Sec complex selectively blocks transport of post-translationally translocated proteins, Jae Kyo Yi, Hidenobu Fujita, Elisabet C. Mandon, and Reid Gilmore

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Cellular and Tissue Selectivity of AAV Serotypes for Gene Delivery to Chondrocytes and Cartilage, Dong Suk Yoon, Kyoung-Mi Lee, Sehee Cho, Eun Ae Ko, Jihyun Kim, Sujin Jung, Jae-Hyuck Shim, Guangping Gao, Kwang Hwan Park, and Jin Woo Lee

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Progesterone stimulates histone citrullination to increase IGFBP1 expression in uterine cells, Coleman H. Young, Bryce Snow, Stanley B. DeVore, Adithya Mohandass, Venkatesh V. Nemmara, Paul R. Thompson, Baskaran Thyagarajan, Amy M. Navratil, and Brian D. Cherrington

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Gut microbial biomarkers for the treatment response in first-episode, drug-naive schizophrenia: a 24-week follow-up study, Xiuxia Yuan, Yunpeng Wang, Xue Li, Jiajun Jiang, Yulin Kang, Lijuan Pang, Peifen Zhang, Ang Li, Luxian Lv, Ole A. Andreassen, Xiaoduo Fan, Shaohua Hu, and Xueqin Song

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Changes in depressive symptoms and cognitive impairment in older long-stay nursing home residents in the USA: a latent transition analysis, Yiyang Yuan, Kate L. Lapane, Anthony J. Rothschild, and Christine M. Ulbricht

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Physical frailty and cognitive impairment in older nursing home residents: a latent class analysis, Yiyang Yuan, Kate L. Lapane, Jennifer Tjia, Jonggyu Baek, Shao-Hsien Liu, and Christine M. Ulbricht

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Novel Gene Mutations Regulating Immune Responses in Autoimmune Polyglandular Syndrome With an Atypical Course, Marina Yukina, Taisia Erofeeva, Nurana Nuralieva, Tatiana Andreeva, Elena Savvateeva, Natalia Dudko, Ekaterina Troshina, Evgeny I. Rogaev, and Galina Melnichenko

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Pharmacokinetic equivalence of CT-P17 to high-concentration (100 mg/ml) reference adalimumab: A randomized phase I study in healthy subjects, Kyung-Sang Yu and Jonathan Kay

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Knowledge-based planning in robotic intracranial stereotactic radiosurgery treatments, Suhong Yu, Huijun Xu, Yin Zhang, Xin Zhang, Michael A. Dyer, Ariel E. Hirsch, Minh Tam Truong, and Heming Zhen

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A benchmark and an algorithm for detecting germline transposon insertions and measuring de novo transposon insertion frequencies, Tianxiong Yu, Xiao Huang, Shengqian Dou, Xiaolu Tang, Shiqi Luo, William E. Theurkauf, Jian Lu, and Zhiping Weng

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RIPK1 activation mediates neuroinflammation and disease progression in multiple sclerosis, Matija Zelic, Boyao Zhang, M. Pontus A. Orning, Egil Lien, and Dimitry Ofengeim

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Geriatric Conditions Are Associated With Decreased Anticoagulation Use in Long-Term Care Residents With Atrial Fibrillation, Ning Zhang, Jay K. Patel, Zhiyong Chen, Yanhua Zhou, Sybil L. Crawford, David D. McManus, Jerry H. Gurwitz, Theresa I. Shireman, and Alok Kapoor

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Optimized RNA-targeting CRISPR/Cas13d technology outperforms shRNA in identifying functional circRNAs, Yang Zhang, Tuan M. Nguyen, Xiao-Ou Zhang, Limei Wang, Tin Phan, John G. Clohessy, and Pier Paolo Pandolfi

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Vectored Immunotherapeutics for Infectious Diseases: Can rAAVs Be The Game Changers for Fighting Transmissible Pathogens?, Wei Zhan, Manish Muhuri, Phillip W. L. Tai, and Guangping Gao

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Randomized controlled trial of sulforaphane and metabolite discovery in children with Autism Spectrum Disorder, Andrew W. Zimmerman, Kanwaljit Singh, Susan Connors, Hua Liu, Anita A. Panjwani, Li-Ching Lee, Eileen Diggins, Ann Foley, Stepan Melnyk, Indrapal N. Singh, S. Jill James, Richard E. Frye, and Jed W. Fahey

Publications from 2020

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World Health Organization Guidelines on Treatment of Hepatitis C Virus Infection: Best Practice Advice From the American College of Physicians, George M. Abraham, Adam J. Obley, Linda L. Humphrey, and Amir Qaseem

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International observational atopic dermatitis cohort to follow natural history and treatment course: TARGET-DERM AD study design and rationale, Katrina Abuabara, Jonathan I. Silverberg, Eric L. Simpson, Amy S. Paller, Lawrence F. Eichenfield, Robert Bissonnette, James Krueger, John E. Harris, Laura Dalfonso, Stephanie E. Watkins, Julie M. Crawford, D. Thaci, and Emma Guttman-Yassky

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Modified CHA2DS2-VASc score predicts in-hospital mortality and procedural complications in acute coronary syndrome treated with percutaneous coronary intervention, Ashraf Abugroun, Abdalla Hassan, Safwan Gaznabi, Hakeem Ayinde, Ahmed Subahi, Mohammed Samee, Adhir Shroff, and Lloyd W. Klein

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Multimorbidity, physical frailty, and self-rated health in older patients with atrial fibrillation, Hawa Ozien Abu, Jane Saczynski, Jordy Mehawej, Tenes Paul, Hamza Awad, Benita A. Bamgbade, Isabelle C. Pierre-Louis, Mayra Tisminetzky, Catarina I. Kiefe, Robert J. Goldberg, and David D. McManus

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Clinically Meaningful Change in Quality of Life and Associated Factors Among Older Patients With Atrial Fibrillation, Hawa Ozien Abu, Jane S. Saczynski, Jordy Mehawej, Mayra Tisminetzky, Catarina I. Kiefe, Robert J. Goldberg, and David D. McManus

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The long non-coding RNA LUCAT1 is a negative feedback regulator of interferon responses in humans, Shiuli Agarwal, Tim Vierbuchen, Sreya Ghosh, Jennie Chan, Zhaozhao Jiang, Richard K. Kandasamy, Emiliano Ricci, and Katherine A. Fitzgerald

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Long Non-coding RNA LincRNA-EPS Inhibits Host Defense Against Listeria monocytogenes Infection, Federica Agliano, Katherine A. Fitzgerald, Anthony T. Vella, Vijay A. Rathinam, and Andrei E. Medvedev

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RNA Therapeutics Are Stepping Out of the Maze, Sudhir Agrawal

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Origami-Inspired Approaches for Biomedical Applications, Abdor Rahman Ahmed, Olivia C. Gauntlett, and Gulden Camci-Unal

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Inherent regulatory asymmetry emanating from network architecture in a prevalent autoregulatory motif, Zulfikar Ali, Vinuselvi Parisutham, Sandeep Choubey, and Robert C. Brewster

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A conserved myotubularin-related phosphatase regulates autophagy by maintaining autophagic flux, Elizabeth A. Allen, Clelia Amato, Tina M. Fortier, Panagiotis D. Velentzas, Will Wood, and Eric H. Baehrecke

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Interchangeability of Biosimilars: What Level of Clinical Evidence is Needed to Support the Interchangeability Designation in the United States, Daniel F. Alvarez, Gertjan Wolbink, Carol Cronenberger, John Orazem, and Jonathan Kay