Open Access is free, unrestricted, online access to scientific and scholarly research. This collection includes Open Access journal articles and other materials authored by researchers, faculty, staff, and students of the University of Massachusetts Medical School.

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Publications from 2020

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Biomarker Exploration in Human Peripheral Blood Mononuclear Cells for Monitoring Sulforaphane Treatment Responses in Autism Spectrum Disorder, Hua Liu, Andrew W. Zimmerman, Kanwaljit Singh, Susan Connors, Eileen Diggins, Katherine K. Stephenson, Albena T. Dinkova-Kostova, and Jed W. Fahey

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Multivalent interactions drive nucleosome binding and efficient chromatin deacetylation by SIRT6, Wallace H. Liu, Jie Zheng, Jessica L. Feldman, Mark A. Klein, Vyacheslav I. Kuznetsov, Craig L. Peterson, Patrick R. Griffin, and John M. Denu

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Solute Carrier Family 1 (SLC1A1) Contributes to Susceptibility and Psychopathology Symptoms of Schizophrenia in the Han Chinese Population, Wenqiang Li, Xi Su, Tengfei Chen, Zhen Li, Yongfeng Yang, Luwen Zhang, Qing Liu, Minglong Shao, Yan Zhang, Minli Ding, Yanli Lu, Hongyan Yu, Xiaoduo Fan, Meng Song, and Luxian Lv

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Fucoxanthin attenuates LPS-induced acute lung injury via inhibition of the TLR4/MYD88 signaling axis, Xiaoling Li, Riming Huang, Kaifeng Liu, Mingyue Li, Hui Luo, Liao Cui, Lei Huang, and Lianxiang Luo

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Transcriptomic profiling reveals extraordinary diversity of venom peptides in unexplored predatory gastropods of the genus Clavus, Aiping Lu, Maren Watkins, Qing Li, Samuel D. Robinson, Gisela P. Concepcion, Mark Yandell, Zhiping Weng, Baldomero M. Olivera, Helena Safavi-Hemami, and Alexander E. Fedosov

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Immunotherapy for Infarcts: In Vivo Postinfarction Macrophage Modulation Using Intramyocardial Microparticle Delivery of Map4k4 Small Interfering RNA, Jun Luo, Matthew S. Weaver, Timothy P. Fitzgibbons, Myriam Aouadi, Michael P. Czech, and Margaret D. Allen

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Ik2/TBK1 and Hook/Dynein, an adaptor complex for early endosome transport, are genetic modifiers of FTD-associated mutant CHMP2B toxicity in Drosophila, Yubing Lu, Ryan J. H. West, Marine Pons, Sean T. Sweeney, and Fen-Biao Gao

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Single-Stranded Phosphorothioated Regions Enhance Cellular Uptake of Cholesterol-Conjugated siRNA but Not Silencing Efficacy, Socheata Ly, Dimas Echeverria, Jacquelyn Sousa, and Anastasia Khvorova

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Seroprevalence of SARS-CoV-2-Specific IgG Antibodies Among Adults Living in Connecticut: Post-Infection Prevalence (PIP) Study, Shiwani Mahajan, Lokinendi V. Rao, and Harlan M. Krumholz

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Dormancy-to-death transition in yeast spores occurs due to gradual loss of gene-expressing ability, Theo Maire, Tim Allertz, Max A. Betjes, and Hyun Youk

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Molecular analysis of a rare case of low-grade primary peritoneal serous carcinoma in a male, Vladislav V. Makarenko, Dina Kandil, Ediz F. Cosar, Lloyd Hutchinson, and Ashraf Khan

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Dysbiosis in a canine model of human fistulizing Crohn's disease, Ana Maldonado-Contreras, Lluis Ferrer, Caitlin Cawley, Sarah Crain, Shakti Bhattarai, Juan Toscano, Doyle V. Ward, and Andrew Hoffman

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From aggressive to assertive, Mary E. Maloney and Patricia Moore

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Genome analysis of American minks reveals link of mutations in Ras-related protein-38 gene to Moyle brown coat phenotype, Andrey D. Manakhov, Maria Yu. Mintseva, Igor A. Andreev, Lev I. Uralsky, Tatiana V. Andreeva, Oleg V. Trapezov, and Evgeny I. Rogaev

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Insulin-Like Growth Factor 2 mRNA-Binding Protein 3 Modulates Aggressiveness of Ewing Sarcoma by Regulating the CD164-CXCR4 Axis, Caterina Mancarella, Giulia Caldoni, Irene Ribolsi, Alessandro Parra, Maria Cristina Manara, Arthur M. Mercurio, Andrea Morrione, and Katia Scotlandi

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Targeting Epigenetic Mechanisms to Alleviate Alcoholic Steatosis, Pranoti Mandrekar

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Real-world outcomes of long-term prednisone and deflazacort use in patients with Duchenne muscular dystrophy: experience at a single, large care center, Jessica R. Marden, Jonathan Freimark, Zhiwen Yao, James Signorovitch, Cuixia Tian, and Brenda L. Wong

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Hypertension and diabetes treatment affordability and government expenditures following changes in patient cost sharing in the "Farmacia popular" program in Brazil: an interrupted time series study, Isabel Cristina Martins Emmerick, Monica Rodrigues Campos, Rondineli Mendes. da Silva, Luisa Arueira Chaves, Andrea Damaso Bertoldi, Dennis Ross-Degnan, and Vera Lucia Luiza

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Cytomegalovirus-Specific T Cell Epitope Recognition in Congenital Cytomegalovirus Mother-Infant Pairs, Emma C. Materne, Daniele Lilleri, Francesca Garofoli, Giuseppina Lombardi, Milena Furione, Maurizio Zavattoni, and Laura L. Gibson

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Enhancing Success of Medicare's Shared Decision Making Mandates Using Implementation Science: Examples Applying the Pragmatic Robust Implementation and Sustainability Model (PRISM), Daniel D. Matlock, Mayuko Ito Fukunaga, Andy Tan, Chris Knoepke, Demetria M. McNeal, Kathleen M. Mazor, and Russell E. Glasgow

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Avoiding Drug Resistance by Substrate Envelope-Guided Design: Toward Potent and Robust HCV NS3/4A Protease Inhibitors, Ashley N. Matthew, Jacqueto Zephyr, Nageswara Rao Desaboini, Mina Henes, Wasih Kamran, Klajdi Kosovrasti, Adam Hedger, Gordon J. Lockbaum, Jennifer Timm, Akbar Ali, Nese Kurt Yilmaz, and Celia A. Schiffer

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Pain Care in the Department of Veterans Affairs: Understanding How a Cultural Shift in Pain Care Impacts Provider Decisions and Collaboration, Kristin M. Mattocks, Marc I. Rosen, John Sellinger, Tu Ngo, Brad Brummett, Diana M. Higgins, Thomas E. Reznik, Paul Holtzheimer, Alicia M. Semiatin, Todd Stapley, and Steve Martino

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A systematic re-examination of processing of MHCI-bound antigenic peptide precursors by ER aminopeptidase 1, George Mavridis, Richa Arya, Alexander Domnick, Jerome Zoidakis, Manousos Makridakis, Antonia Vlahou, Anastasia Mpakali, Angelos Lelis, Dimitris Georgiadis, Robert Tampe, Athanasios Papakyriakou, Lawrence J. Stern, and Efstratios Stratikos

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Light Forge: A Microfluidic DNA Melting-based Tuberculosis Test, Ian M. Mbano, Tawanda Mandizvo, Jerome Rogich, Tafara T. R. Kunota, Jared S. Mackenzie, Manormoney Pillay, and Frederick K. Balagadde

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Loss of huntingtin function slows synaptic vesicle endocytosis in striatal neurons from the htt(Q140/Q140) mouse model of Huntington's disease, Robyn L. McAdam, Andrew Morton, Sarah L. Gordon, Julia F. Alterman, Anastasia Khvorova, Michael A. Cousin, and Karen J. Smillie

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Individual vs. Group Delivery of Acupuncture Therapy for Chronic Musculoskeletal Pain in Urban Primary Care-a Randomized Trial, M. Diane McKee, Arya Nielsen, Belinda Anderson, Elizabeth Chuang, Mariel Connolly, Qi Gao, Eric N. Gil, Claudia Lechuga, Mimi Kim, Huma Naqvi, and Benjamin Kligler

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A 4-Base-Pair Core-Enclosing Helix in Telomerase RNA Is Essential for Activity and for Binding to the Telomerase Reverse Transcriptase Catalytic Protein Subunit, Melissa A. Mefford, Evan P. Hass, and David C. Zappulla

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Synthesis and applications of theranostic oligonucleotides carrying multiple fluorine atoms, Valeriy G. Metelev and Alexei A. Bogdanov

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YAP/TAZ deficiency reprograms macrophage phenotype and improves infarct healing and cardiac function after myocardial infarction, Masum M. Mia, Dasan Mary Cibi, Siti Aishah Abdul Ghani Binte, Weihua Song, Nicole Tee, Sujoy Ghosh, Junhao Mao, Eric N. Olson, and Manvendra K. Singh

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Astrocyte- and Neuron-Derived CXCL1 Drives Neutrophil Transmigration and Blood-Brain Barrier Permeability in Viral Encephalitis, Benedict D. Michael, Laura Bricio-Moreno, Elizabeth W. Sorensen, Yoshishige Miyabe, Jeffrey Lian, Tom Solomon, Evelyn A. Kurt-Jones, and Andrew D. Luster

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Histone deacetylases 1 and 2 silence cryptic transcription to promote mitochondrial function during cardiogenesis, Zachary J. Milstone, Sherin Saheera, Lauren Bourke, Tomer Shpilka, Cole M. Haynes, and Chinmay M. Trivedi

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First Pass Effect in Patients Treated With the Trevo Stent-Retriever: A TRACK Registry Study Analysis, Maxim Mokin and Ajit S. Puri

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A Developmental Analysis of Juxtavascular Microglia Dynamics and Interactions with the Vasculature, Erica Mondo, Shannon C. Becker, Amanda G. Kautzman, Martina Schifferer, Christina E. Baer, Jiapei Chen, Eric J. Huang, Mikael Simons, and Dorothy P. Schafer

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A curated benchmark of enhancer-gene interactions for evaluating enhancer-target gene prediction methods, Jill E. Moore, Henry E. Pratt, Michael J. Purcaro, and Zhiping Weng

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Association of smoking and right ventricular function in middle age: CARDIA study, Henrique T. Moreira, Anderson C. Armstrong, Chike C. Nwabuo, Henrique D. Vasconcellos, Andre Schmidt, Ravi K. Sharma, Bharath Ambale-Venkatesh, Mohammad R. Ostovaneh, Catarina I. Kiefe, Cora E. Lewis, Pamela J. Schreiner, Stephen Sidney, Kofo O. Ogunyankin, Samuel S. Gidding, and Joao A. C. Lima

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Reducing barriers to post-9/11 veterans' use of programs and services as they transition to civilian life, Nicole R. Morgan, Keith R. Aronson, Daniel F. Perkins, Julia A. Bleser, Katie Davenport, Dawne Vogt, Laurel A. Copeland, Erin P. Finley, and Cynthia L. Gilman

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Association of Damaging Variants in Genes With Increased Cancer Risk Among Patients With Congenital Heart Disease, Sarah U. Morton, Peter E. Newburger, and Christine E. Seidman

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Global FKRP Registry: observations in more than 300 patients with Limb Girdle Muscular Dystrophy R9, Lindsay B. Murphy, John Herbert Stevenson, and Volker Straub

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Identifying unreliable predictions in clinical risk models, Paul D. Myers, Kenney Ng, Kristen Severson, Uri Kartoun, Wangzhi Dai, Wei Huang, Frederick A. Anderson Jr., and Collin M. Stultz

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Network Meta-Analysis of Ulcerative Colitis Pharmacotherapies: Carryover Effects from Induction and Bias of the Results, Dominik Naessens, Chris Cameron, and David C. Hoaglin

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Teamwork for smoking cessation: which smoker was willing to engage their partner? Results from a cross-sectional study, Catherine S. Nagawa, Oluwabunmi M. Emidio, Kate L. Lapane, Thomas K. Houston, Bruce A. Barton, Jamie Faro, Amanda C. Blok, Elizabeth Aaker Orvek, Sarah L. Cutrona, Bridget M. Smith, Jeroan J. Allison, and Rajani S. Sadasivam

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Natural variation in a glucuronosyltransferase modulates propionate sensitivity in a C. elegans propionic acidemia model, Huimin Na, Stefan Zdraljevic, Robyn E. Tanny, Albertha J. M. Walhout, and Erik C. Andersen

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Pediatric Refugee Health Care Delivery in the Community Setting: An Educational Workshop for Multidisciplinary Family-Centered Care During Resettlement, Umbereen S. Nehal, Satoko Kanahara, Mihoko Tanabe, Grace Hayner, and Brett D. Nelson

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Robustness of sex-differences in functional connectivity over time in middle-aged marmosets, Benjamin C. Nephew, Marcelo Febo, Ryan Cali, Kathryn P. Workman, Laurellee Payne, Constance M. Moore, Jean A. King, and Agnes Lacreuse

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Defining trained immunity and its role in health and disease, Mihai G. Netea and Eicke Latz

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The validation of organisational culture assessment instrument in healthcare setting: results from a cross-sectional study in Vietnam, Huy Nguyen, Nguyen Thi Hoai Thu, Nguyen Le Tuan Anh, Nguyen Thanh Hai Au, Nguyen The Phuong, Nguyen Thi Cham, and Pham Duc Minh

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Group Acupuncture Therapy With Yoga Therapy for Chronic Neck, Low Back, and Osteoarthritis Pain in Safety Net Setting for an Underserved Population: Design and Rationale for a Feasibility Pilot, Arya Nielsen, Ray Teets, Steffany Moonaz, Belinda J. Anderson, Eve Walter, Mirta Milanes, Donna M. Mah, M. Diane McKee, and Benjamin Kligler

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Interpretation of the Epigenetic Signature of Facioscapulohumeral Muscular Dystrophy in Light of Genotype-Phenotype Studies, Ana Nikolic, Louise Maranda, and Rossella Ginevra Tupler

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Opioid initiation and injection transition in rural northern New England: A mixed-methods approach, Kerry Nolte, Aurora L. Drew, Peter D. Friedmann, Eric Romo, Linda M. Kinney, and Thomas J. Stopka

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Coffee and tea consumption in the early adult lifespan and left ventricular function in middle age: the CARDIA study, Chike C. Nwabuo, Aisha S. Betoko, Jared P. Reis, Henrique T. Moreira, Henrique D. Vasconcellos, Eliseo Guallar, Christopher Cox, Stephen Sidney, Bharath Ambale-Venkatesh, Cora E. Lewis, Pamela J. Schreiner, Donald Lloyd-Jones, Catarina I. Kiefe, Samuel S. Gidding, and Joao A. C. Lima

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Proteomic and Transcriptional Profiles of Human Stem Cell-Derived beta Cells Following Enteroviral Challenge, Julius O. Nyalwidhe, Agata Jurczyk, Basanthi Satish, Sambra D. Redick, Natasha Qaisar, Melanie I. Trombly, Pranitha Vangala, Riccardo Racicot, Rita Bortell, David M. Harlan, Dale L. Greiner, Michael A. Brehm, Jerry L. Nadler, and Jennifer P. Wang

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LHRH-Conjugated Drugs as Targeted Therapeutic Agents for the Specific Targeting and Localized Treatment of Triple Negative Breast Cancer, J. D. Obayemi, A. A. Salifu, S. C. Eluu, V. O. Uzonwanne, S. M. Jusu, C. C. Nwazojie, C. E. Onyekanne, Ogooluwa Ojelabi, L. Payne, Constance M. Moore, Jean A. King, and W. O. Soboyejo

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Descriptive Comparisons of the Impact of Apremilast and Methotrexate Monotherapy in Oligoarticular Psoriatic Arthritis: the Corrona Psoriatic Arthritis/Spondyloarthritis Registry Results, Alexis Ogdie, Mei Liu, Meghan Glynn, Kelechi Emeanuru, Leslie R. Harrold, Sven Richter, Benoit Guerette, and Philip J. Mease

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TRIM34 restricts HIV-1 and SIV capsids in a TRIM5alpha-dependent manner, Molly Ohainle, Kyusik Kim, Sevnur Komurlu Keceli, Abby Felton, Ed Campbell, Jeremy Luban, and Michael Emerman

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JC Virus infected choroid plexus epithelial cells produce extracellular vesicles that infect glial cells independently of the virus attachment receptor, Bethany A. O'Hara, Jenna Morris-Love, Gretchen V. Gee, Sheila A. Haley, and Walter J. Atwood

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Wild-type huntingtin regulates human macrophage function, Grace C. O'Regan, Sahar H. Farag, Gary R. Ostroff, Sarah J. Tabrizi, and Ralph Andre

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A cognitive remediation training for young adults with psychotic disorders to support their participation in education - study protocol for a pilot randomized controlled trial, Lana K. M. Otto, Jacomijn Hofstra, Michelle G. Mullen, Derek Malenczak, Nynke Boonstra, Lisette van der Meer, Wim Veling, Cees Boerhout, Gerard D. van Rijsbergen, Jos de Vries, Boudien van der Pol, Gerdina H. M. Pijnenborg, and Lies Korevaar

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Dynamics of the 4D genome during in vivo lineage specification and differentiation, A. Marieke Oudelaar, Daniel Hidalgo, Merav Socolovsky, Douglas R. Higgs, and Jim R. Hughes

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dagLogo: An R/Bioconductor package for identifying and visualizing differential amino acid group usage in proteomics data, Jianhong Ou, Haibo Liu, Niraj K. Nirala, Alexey Stukalov, Usha Acharya, Michael R. Green, and Lihua Julie Zhu

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The clinical utilities of multi-pinhole single photon emission computed tomography, Ilker Ozsahin, Ling Chen, Arda Konik, Michael A. King, Freek J. Beekman, and Greta S. P. Mok

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CK2-Dependent Phosphorylation of the Brg1 Chromatin Remodeling Enzyme Occurs during Mitosis, Teresita Padilla-Benavides, Dominic T. Haokip, Yeonsoo Yoon, Pablo Reyes-Gutierrez, Jaime A. Rivera, and Anthony N. Imbalzano

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Adaptive Evolution Targets a piRNA Precursor Transcription Network, Swapnil Parhad, Tianxiong Yu, Gen Zhang, Nicholas P. Rice, Zhiping Weng, and William E. Theurkauf

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Therapeutic inhibition of FcgammaRIIb signaling targets leukemic stem cells in chronic myeloid leukemia, Oliver Parting, Samantha Langer, Maja Kim Kuepper, Caroline Wessling, Shaoguang Li, Till Braunschweig, Nicolas Chatain, Tiago Maie, Ivan G. Costa, Martina Crysandt, Michael Huber, Tim H. Brummendorf, Steffen Koschmieder, and Mirle Schemionek

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Addressing decontaminated respirators: Some methods appear to damage mask integrity and protective function, Richard E. Peltier, Jiayuan Wang, Brian L. Hollenbeck, Jennifer Lanza, Ryan M. Furtado, Jay Cyr, Richard T. Ellison III, and Kimiyoshi J. Kobayashi

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Theme Trends and Knowledge Structure on Mobile Health Apps: Bibliometric Analysis, Cheng Peng, Miao He, Sarah L. Cutrona, Catarina I. Kiefe, Feifan Liu, and Zhongqing Wang

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Caspase-8 mediates inflammation and disease in rodent malaria, Larissa M. N. Pereira, Patricia Aparecida Assis, Natalia M. de Araujo, Danielle Fernandes Durso, Caroline Junqueira, Marco Antonio Ataide, Dhelio B. Pereira, Egil Lien, Katherine A. Fitzgerald, Dario S. Zamboni, Douglas T. Golenbock, and Ricardo T. Gazzinelli

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Lipophilic dye-compatible brain clearing technique allowing correlative magnetic resonance/high-resolution fluorescence imaging in rat models of glioblastoma, Marco Peviani, Giorgia Spano, Antonella Pagani, Gianluca Brugnara, Cesare Covino, Rossella Galli, Alessandra Biffi, and Letterio S. Politi

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TIM, a targeted insertional mutagenesis method utilizing CRISPR/Cas9 in Chlamydomonas reinhardtii, Tyler Picariello, Yuqing Hou, Tomohiro Kubo, Nathan A. McNeill, Haru-Aki Yanagisawa, Toshiyuki Oda, and George B. Witman

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Association of Childhood Psychosocial Environment With 30-Year Cardiovascular Disease Incidence and Mortality in Middle Age, Jacob B. Pierce, Kiarri N. Kershaw, Catarina I. Kiefe, David R. Jacobs Jr., Stephen Sidney, Sharon Stein. Merkin, and Joe Feinglass

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Medialized Total Ossicular Replacement Prosthesis, Marc D. Polanik and Aaron K. Remenschneider

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Utilization of ACP CPT codes among high-need Medicare beneficiaries in 2017: A brief report, Amanda J. Reich, Ginger Jin, Avni Gupta, Dae Kim, Stuart Lipstiz, Holly G. Prigerson, Jennifer Tjia, Keren Ladin, Scott D. Halpern, Zara Cooper, and Joel S. Weissman

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Machine Learning Model Based on Transthoracic Bioimpedance and Heart Rate Variability for Lung Fluid Accumulation Detection: Prospective Clinical Study, Natasa Reljin, Hugo F. Posada-Quintero, Caitlin Eaton-Robb, Sophia Binici, Emily Ensom, Eric Y. Ding, Anna Hayes, Jarno Riistama, Chad E. Darling, David D. McManus, and Ki H. Chon

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Large genotype-phenotype study in carriers of D4Z4 borderline alleles provides guidance for facioscapulohumeral muscular dystrophy diagnosis, Giulia Ricci and Rossella Ginevra Tupler

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An atlas of cell types in the mouse epididymis and vas deferens, Vera D. Rinaldi, Elisa Donnard, Kyle Gellatly, Morten Rasmussen, Alper Kucukural, Onur Yukselen, Manuel Garber, Upasna Sharma, and Oliver J. Rando

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Platelets Fuel the Inflammasome Activation of Innate Immune Cells, Verena Rolfes, Lucas Secchim Ribeiro, Eicke Latz, Moshe Arditi, and Bernardo Simoes Franklin

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HIF-1 Has a Central Role in Caenorhabditis elegans Organismal Response to Selenium, Laura Romanelli-Credrez, Maria Doitsidou, Mark J. Alkema, and Gustavo Salinas

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Learning Latent Space Representations to Predict Patient Outcomes: Model Development and Validation, Subendhu Rongali, Adam J. Rose, David D. McManus, Adarsha Bajracharya, Alok Kapoor, Edgard A. Granillo, and Hong Yu

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The relationship between a microfinance-based healthcare delivery platform, health insurance coverage, health screenings, and disease management in rural Western Kenya, Molly Rosenberg, James Akiruga Amisi, Daria Szkwarko, Dan N. Tran, Becky Genberg, Maya Luetke, Sina Kianersi, Jane Namae, Jeremiah Laktabai, and Sonak Pastakia

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Evolved bacterial resistance against fluoropyrimidines can lower chemotherapy impact in the Caenorhabditis elegans host, Brittany Rosener, Serkan Sayin, Peter O. Oluoch, Aurian Garcia-Gonzalez, Hirotada Mori, Albertha J. M. Walhout, and Amir Mitchell

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Prospective, multicenter study of P4HB (Phasix) mesh for hernia repair in cohort at risk for complications: 3-Year follow-up, John Scott Roth, John R. Romanelli, and Raymond M. Dunn

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Resolution of Severe Graft Steatosis Before Living-Donor Liver Transplant After 86 Pounds of Weight Loss, John G. Roubil, Paulo N.A. Martins, Movahedi Babak, Jacob R. Bledsoe, Bryce M. Bludevich, Curtis T. Barry, and Adel Bozorgzadeh

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Physician Anxiety and Burnout: Symptom Correlates and a Prospective Pilot Study of App-Delivered Mindfulness Training, Alexandra Roy, Susan Druker, Elizabeth A. Hoge, and Judson A. Brewer

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Phenotypic Variability Among Patients With D4Z4 Reduced Allele Facioscapulohumeral Muscular Dystrophy, Lucia Ruggiero and Rossella Tupler

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Secure Asynchronous Communication Between Smokers and Tobacco Treatment Specialists: Secondary Analysis of a Web-Assisted Tobacco Intervention in the QUIT-PRIMO and National Dental PBRN Networks, Rajani S. Sadasivam, Ariana Kamberi, Kathryn Delaughter, Barrett Phillips, Jessica H. Williams, Sarah L. Cutrona, Midge N. Ray, Gregg H. Gilbert, and Thomas K. Houston

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Evaluation of pre-processing on the meta-analysis of DNA methylation data from the Illumina HumanMethylation450 BeadChip platform, Claudia Sala, Pietro Di Lena, Danielle Fernandes Durso, Andrea Prodi, Gastone Castellani, and Christine Nardini

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A case of solitary kidney with duplex collecting systems and renal vascular variants in an adult male cadaver, Mehdi S. Salimy, Gabrielle A. Luiselli, Megan Yuen, Rose C. Healy, S. G. Shah, Eustathia Lela Giannaris, Manas Das, and Alexandra E. Wink

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Does DNA Methylation Matter in FSHD, Valentina Salsi, Frederique Magdinier, and Rossella Ginevra Tupler

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A new paraprobiotic-based treatment for control of Haemonchus contortus in sheep, John Sanders, David Gazzola, Hanchen Li, Ambily Abraham, Kelly Flanagan, Florentina Rus, Yan Hu, Gary R. Ostroff, and Raffi V. Aroian

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Rates of Potentially Inappropriate Dosing of Direct-Acting Oral Anticoagulants and Associations With Geriatric Conditions Among Older Patients With Atrial Fibrillation: The SAGE-AF Study, Saket Sanghai, Cecillia Wong, Ziyue Wang, Pia Clive, Wenisa Tran, Molly Waring, Robert J. Goldberg, Robert Hayward, Jane S. Saczynski, and David D. McManus

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Identifying the fundamental structures and processes of care contributing to emergency general surgery quality using a mixed-methods Donabedian approach, Heena P. Santry, Scott A. Strassels, Angela M. Ingraham, Wendelyn M. Oslock, Kevin B. Ricci, Anghela Z. Paredes, Victor K. Heh, Holly E. Baselice, Amy P. Rushing, Adrian Diaz, Vijaya Daniel, M. Didem Ayturk, and Catarina I. Kiefe

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Data on enrichment of chitosan nanoparticles for intranasal delivery of oligonucleotides to the brain, Vasyl Sava, Oksana Fihurka, Anastasia Khvorova, and Juan Sanchez-Ramos

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Pancreatic Polypeptide but Not Other Members of the Neuropeptide Y Family Shows a Moderate Association With Perceived Anxiety in Obese Men, Selina Johanna Schaper, Tobias Hofmann, Ellen Wolk, Elena Weibert, Matthias S. F. Rose, and Andreas Stengel

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Rare and Common Genetic Variants, Smoking, and Body Mass Index: Progression and Earlier Age of Developing Advanced Age-Related Macular Degeneration, Johanna M. Seddon, Rafael Widjajahakim, and Bernard Rosner

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A re-evaluation of silk measurement by the cecropia caterpillar (Hyalophora cecropia) during cocoon construction reveals use of a silk odometer that is temporally regulated, Hana Sehadova, Patrick A. Guerra, Ivo Sauman, and Steven M. Reppert

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Thioredoxin Interacting Protein Is Required for a Chronic Energy-Rich Diet to Promote Intestinal Fructose Absorption, Anu Shah, Sezin Dagdeviren, Jordan P. Lewandowski, Angela B. Schmider, Elisabeth M. Ricci-Blair, Niranjana Natarajan, Henna Hundal, Hye Lim Noh, Randall H. Friedline, Charles Vidoudez, Jason K. Kim, Amy J. Wagers, Roy J. Soberman, and Richard T. Lee

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Transparent soil microcosms for live-cell imaging and non-destructive stable isotope probing of soil microorganisms, Kriti Sharma, Marton Palatinszky, Georgi Nikolov, David Berry, and Elizabeth A. Shank

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Development of Complement Factor H-Based Immunotherapeutic Molecules in Tobacco Plants Against Multidrug-Resistant Neisseria gonorrhoeae, Jutamas Shaughnessy, Y. Tran, Bo Zheng, Rosane B. DeOliveira, Sunita Gulati, Wen-Chao Song, James M. Maclean, Keith L. Wycoff, and Sanjay Ram

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Are dietary fish oil supplements appropriate for dyslipidemia management? A review of the evidence, Samuel C. R. Sherratt, Michael Lero, and R. Preston Mason

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Impact of Patient-Clinical Team Secure Messaging on Communication Patterns and Patient Experience: Randomized Encouragement Design Trial, Stephanie L. Shimada, Mark S. Zocchi, Timothy P. Hogan, Stefan G. Kertesz, Armando J. Rotondi, Jorie M. Butler, Sara J. Knight, Kathryn DeLaughter, Felicia Kleinberg, Jeff Nicklas, Kim M. Nazi, and Thomas K. Houston

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Content and Performance of the MiniMUGA Genotyping Array: A New Tool To Improve Rigor and Reproducibility in Mouse Research, John Sebastian Sigmon, Christopher M. Sassetti, Clare M. Smith, and Fernando Pardo Manuel de Villena