Open Access is free, unrestricted, online access to scientific and scholarly research. This collection includes Open Access journal articles and other materials authored by researchers, faculty, staff, and students of the University of Massachusetts Medical School.

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Publications from 2020

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Cell Type Impacts Accessibility of mRNA to Silencing by RNA Interference, Chantal M. Ferguson, Dimas Echeverria, Matthew R. Hassler, Socheata Ly, and Anastasia Khvorova

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Separation Anxiety, Joshua Feriante and Bettina Bernstein

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Neuroacanthocytosis, Joshua Feriante and Vikas Gupta

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REM Rebound Effect, Joshua Feriante and Shantanu Singh

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Chronic recurrent priapism: A high flow state secondary to an arteriovenous fistula of the corpus cavernosum, Catherine M. Fiore, Melissa L. Pellegrino, and Meghna C. Trivedi

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Patient-reported outcomes feedback report for knee arthroplasty patients should present selective information in a simple design - findings of a qualitative study, Kathrin I. Fischer, Diarmuid De Faoite, and Matthias S. F. Rose

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Trajectories of Health-Related Quality of Life and HbA1c Values of Children and Adolescents With Diabetes Mellitus Type 1 Over 6 Months: A Longitudinal Observational Study, Kathrin I. Fischer, Felix H. Fischer, Dana Barthel, Christiane Otto, Ute Thyen, Marcus Klein, Otto Walter, Ulrike Ravens-Sieberer, Matthias S. F. Rose, and Sandra Nolte

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Large domains of heterochromatin direct the formation of short mitotic chromosome loops, Maximilian H. Fitz-James, Pin Tong, Alison L. Pidoux, Hakan Ozadam, Liyan Yang, Sharon A. White, Job Dekker, and Robin C. Allshire

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Comprehensive fitness maps of Hsp90 show widespread environmental dependence, Julia M. Flynn, Ammeret Rossouw, Pamela A. Cote-Hammarlof, Ines Fragata, David Mavor, Carl Hollins III, Claudia Bank, and Daniel N. Bolon

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The Role of Limited English Proficiency and Access to Health Insurance and Health Care in the Affordable Care Act Era, Andriana M. Foiles Sifuentes, Monica Robledo Cornejo, Nien-Chen Li, Maira Castaneda-Avila, Jennifer Tjia, and Kate L. Lapane

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Innate Immunity in the C. elegans Intestine Is Programmed by a Neuronal Regulator of AWC Olfactory Neuron Development, Kyle J. Foster, Hilary K. Cheesman, Pengpeng Liu, Nicholas D. Peterson, Sarah M. Anderson, and Read Pukkila-Worley

Publications from 2021

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Understanding the Impact of Teledermatology on No-Show Rates and Healthcare Accessibility: A Retrospective Chart Review, Ellen B. Franciosi, Alice J. Tan, Bina Kassamali, Daniel M. O'Connor, Medhi Rashighi, and Avery LaChance

Publications from 2020

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From Tank to Treatment: Modeling Melanoma in Zebrafish, William Tyler Frantz and Craig J. Ceol

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Validation and preliminary data from a health-related quality of life questionnaire for owners of dogs with cardiac disease, Lisa M. Freeman, John E. Rush, Melissa A. Clark, and Barret J. Bulmer

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Predicting the 10-year risk of death from other causes in men with localized prostate cancer using patient-reported factors: Development of a tool, Daniel M. Frendl, Gordon A. FitzGerald, Mara M. Epstein, Jeroan J. Allison, Mitchell H. Sokoloff, and John E. Ware Jr.

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Premature termination codon readthrough upregulates progranulin expression and improves lysosomal function in preclinical models of GRN deficiency, Jonathan Frew, Fen-Biao Gao, and Haakon B. Nygaard

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Non-neutralizing antibody responses following A(H1N1)pdm09 influenza vaccination with or without AS03 adjuvant system, Damien Friel, Mary Dawn T. Co, Thierry Ollinger, Bruno Salaun, Anne Schuind, Ping Li, Karl Walravens, Francis A. Ennis, and David W. Vaughn

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beta-Amyloid Clustering around ASC Fibrils Boosts Its Toxicity in Microglia, Lea L. Friker, Hannah Scheiblich, Inga V. Hochheiser, Rebecca Brinkschulte, Dietmar Riedel, Eicke Latz, Matthias Geyer, and Michael T. Heneka

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Liver-Directed but Not Muscle-Directed AAV-Antibody Gene Transfer Limits Humoral Immune Responses in Rhesus Monkeys, Sebastian P. Fuchs, Jose M. Martinez-Navio, Eva G. Rakasz, Guangping Gao, and Ronald C. Desrosiers

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Early life lessons: The lasting effects of germline epigenetic information on organismal development, Carolina Galan, Marina Krykbaeva, and Oliver J. Rando

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ESRRB regulates glucocorticoid gene expression in mice and patients with acute lymphoblastic leukemia, Kayleigh M. Gallagher, Justine E. Roderick, Shi Hao. Tan, Tze King Tan, Leonard Murphy, Jun Yu, Rui Li, Kevin O'Connor, Lihua Julie Zhu, Michael R. Green, Takaomi Sanda, and Michelle A. Kelliher

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Election 2020: Comparison of the American College of Physicians' Vision for a Better U.S. Health Care System With the Presidential Candidates' Plans, Heather E. Gantzer, Jacqueline W. Fincher, William E. Fox, Gregory C. Kane, Thomas G. Cooney, George M. Abraham, and Rebecca Andrews

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An Innovative Electronic Health Toolkit (Our Whole Lives for Chronic Pain) to Reduce Chronic Pain in Patients With Health Disparities: Open Clinical Trial, Paula Gardiner, Salvatore D'Amico, Man Luo, and Niina Haas

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Current Insights in Cutaneous Lupus Erythematosus Immunopathogenesis, Colton J. Garelli, Maggi Ahmed Refat, Padma P. Nanaware, Zaida G. Ramirez-Ortiz, Medhi Rashighi, and Jillian M. Richmond

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Extracellular microRNAs in human circulation are associated with miRISC complexes that are accessible to anti-AGO2 antibody and can bind target mimic oligonucleotides, Hirosha Geekiyanage, Shima Rayatpisheh, James A. Wohlschlegel, Robert H. Brown Jr., and Victor R. Ambros

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The radiologist empowerment through virtual multidisciplinary tumor boards: The commitment of oncologic care during COVID-19 pandemic, Nicolo Gennaro, Andrea Marrari, Alexia F. Bertuzzi, Luca Balzarini, Armando Santoro, and Letterio S. Politi

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Muscle-Directed Delivery of an AAV1 Vector Leads to Capsid-Specific T Cell Exhaustion in Nonhuman Primates and Humans, Gwladys Gernoux, Alisha M. Gruntman, Meghan Blackwood, Marina Zieger, Terence R. Flotte, and Christian Mueller

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A case report of recurrent spontaneous coronary artery dissection and Takotsubo cardiomyopathy: a treatment dilemma, Hafiz U. Ghafoor, Abhishek Bose, Amr El-Meligy, and Joseph Hannan

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Melting dsDNA Donor Molecules Greatly Improves Precision Genome Editing in Caenorhabditis elegans, Krishna S. Ghanta and Craig C. Mello

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Caenorhabditis elegans methionine/S-adenosylmethionine cycle activity is sensed and adjusted by a nuclear hormone receptor, Gabrielle E. Giese, Melissa D. Walker, Olga Ponomarova, Hefei Zhang, Xuhang Li, Gregory Minevich, and Albertha J. M. Walhout

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Epstein-Barr Virus Epitope-Major Histocompatibility Complex Interaction Combined with Convergent Recombination Drives Selection of Diverse T Cell Receptor alpha and beta Repertoires, Anna Gil, Larisa Kamga, Ramakanth Chirravuri-Venkata, Nuray Aslan, Fransenio G. Clark, Dario Ghersi, Katherine Luzuriaga, and Liisa K. Selin

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LncRNA RP11-19E11 is an E2F1 target required for proliferation and survival of basal breast cancer, A. Giro-Perafita, L. Luo, A. Khodadadi-Jamayran, M. Thompson, Betul Akgol-Oksuz, A. Tsirigos, B. D. Dynlacht, I. Sanchez, and F. J. Esteva

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Prognostic factors for changes in the timed 4-stair climb in patients with Duchenne muscular dystrophy, and implications for measuring drug efficacy: A multi-institutional collaboration, Nathalie Goemans, Brenda L. Wong, Marleen Van den Hauwe, James Signorovitch, Gautam Sajeev, David Cox, John Landry, Madeline Jenkins, Ibrahima Dieye, Zhiwen Yao, Intekhab Hossain, and Susan J. Ward

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The Smoking Gun: Can We Do for Gun Control What We Are Doing to Control the Vaping and E-Cigarettes Epidemic?, Robert J. Goldberg, Kate L. Lapane, Stephenie C. Lemon, and Michael P. Hirsh

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Respiratory Rate Monitoring in Clinical Environments with a Contactless Ultra-Wideband Impulse Radar-based Sensor System, Charlotte E. Goldfine, Farhan Tasnim Oshim, Stephanie P. Carreiro, Brittany P. Chapman, Deepak Ganesan, and Tauhidur Rahman

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Clinicopathologic features of endometrial cancer with mismatch repair deficiency, Sushmita Gordhandas, Ryan M. Kahn, Charlotte Gamble, Nizam Talukdar, Brandon Maddy, Becky Baltich Nelson, Gulce Askin, Paul J. Christos, Kevin Holcomb, Thomas A. Caputo, Eloise Chapman-Davis, and Melissa K. Frey

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Survival following allogeneic transplant in patients with myelofibrosis, Krisstina Gowin and Jan Cerny

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US Food and Drug Administration (FDA) Emergency Use Authorization: Glass Half Full or Glass Half Empty, Roy Guharoy and Edward P. Krenzelok

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Control of Adipocyte Thermogenesis and Lipogenesis through beta3-Adrenergic and Thyroid Hormone Signal Integration, Adilson L. Guilherme, Batuhan Yenilmez, Alexander H. Bedard, Felipe Henriques, Dianxin Liu, Alexandra Lee, Lauren Goldstein, Mark Kelly, Sarah M. Nicoloro, Min Chen, Lee Weinstein, Sheila Collins, and Michael P. Czech

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Myxedema Coma: A Life-Threatening Condition in Patients Using Pembrolizumab, Sangeetha Gummalla, Madhura Manjunath, and Brian Phillips

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Comparison of outcomes of HCT in blast phase of BCR-ABL1- MPN with de novo AML and with AML following MDS, Vikas Gupta and Jan Cerny

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Bayesian variable selection for high dimensional predictors and self-reported outcomes, Xiangdong Gu, Mahlet G. Tadesse, Andrea S. Foulkes, Yunsheng Ma, and Raji Balasubramanian

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Premature Atrial and Ventricular Contraction Detection using Photoplethysmographic Data from a Smartwatch, Dong Han, Syed Khairul Bashar, Fahimeh Mohagheghian, Eric Y. Ding, Cody Whitcomb, David D. McManus, and Ki H. Chon

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Patency of arterial repairs from wartime extremity vascular injuries, Lauren J. Haney, Esther Bae, Mary Jo V. Pugh, Laurel A. Copeland, Chen-Pin Wang, Daniel J. MacCarthy, Megan E. Amuan, and Paula K. Shireman

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Regulation of adipose tissue inflammation by interleukin 6, Myoung Souk Han, Alexis White, Rachel J. Perry, Joao-Paulo Camporez, Juan Hidalgo, Gerald I. Shulman, and Roger J. Davis

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Intramedullary Nailing Versus External Fixation in the Treatment of Open Tibial Fractures in Tanzania: Results of a Randomized Clinical Trial, Billy T. Haonga, Max Liu, Patrick Albright, Sravya T. Challa, Syed H. Ali, Ann A. Lazar, Edmund N. Eliezer, David W. Shearer, and Saam Morshed

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Composite quantitative knee structure metrics predict the development of accelerated knee osteoarthritis: data from the osteoarthritis initiative, Matthew S. Harkey, Julie E. Davis, Lori Lyn Price, Robert J. Ward, James W. MacKay, Charles B. Eaton, Grace H. Lo, Mary F. Barbe, Ming Zhang, Jincheng Pang, Alina C. Stout, Bing Lu, Timothy E. McAlindon, and Jeffrey B. Driban

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Disease activity and patient-reported outcomes in patients with rheumatoid arthritis and Sjogren's syndrome enrolled in a large observational US registry, Leslie R. Harrold, Ying Shan, Sabrina Rebello, Neil Kramer, Sean E. Connolly, Evo Alemao, Sheila Kelly, Joel M. Kremer, and Elliot D. Rosenstein

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Prevalence of Sjogren's syndrome associated with rheumatoid arthritis in the USA: an observational study from the Corrona registry, Leslie R. Harrold, Ying Shan, Sabrina Rebello, Neil Kramer, Sean E. Connolly, Evo Alemao, Sheila Kelly, Joel M. Kremer, and Elliot D. Rosenstein

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Co-Administration of Injected and Oral Vaccine Candidates Elicits Improved Immune Responses over Either Route Alone, Celine A. Hayden, Danilo Landrock, Chiung Yu Hung, Gary R. Ostroff, Gina M. Fake, John H. Walker, Ann Kier, and John A. Howard

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A thermophilic phage uses a small terminase protein with a fixed helix-turn-helix geometry, Janelle A. Hayes, Brendan J. Hilbert, Christl Gaubitz, Nicholas P. Stone, and Brian A. Kelch

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Loss of supervillin causes myopathy with myofibrillar disorganization and autophagic vacuoles, Carola Hedberg-Oldfors, Elizabeth J. Luna, Anders Oldfors, and Cordula Knopp

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Single-Cell RNA Profiling Reveals Adipocyte to Macrophage Signaling Sufficient to Enhance Thermogenesis, Felipe Henriques, Alexander H. Bedard, Adilson L. Guilherme, Mark Kelly, Lawrence M. Lifshitz, Karl D. Bellve, Leslie A. Rowland, Batuhan Yenilmez, Shreya Kumar, Yetao Wang, Jeremy Luban, and Michael P. Czech

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Association between sodium-glucose cotransporter 2 (SGLT2) inhibitors and lower extremity amputation: A systematic review and meta-analysis, James Heyward, Omar Mansour, Lily Olson, Sonal Singh, and G. Caleb Alexander

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Ribosome profiling in mouse hippocampus: plasticity-induced regulation and bidirectional control by TSC2 and FMRP, Annie Hien, Gemma Molinaro, Botao Liu, Kimberly M. Huber, and Joel D. Richter

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Interplay between axonal Wnt5-Vang and dendritic Wnt5-Drl/Ryk signaling controls glomerular patterning in the Drosophila antennal lobe, Huey Hing, Noah Reger, Jennifer Snyder, and Lee G. Fradkin

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Contributions of IFN-gamma and granulysin to the clearance of Plasmodium yoelii blood stage, Natalia Satchiko Hojo-Souza, Patrick Orestes de Azevedo, Julia Teixeira de Castro, Andrea Teixeira-Carvalho, Judy Lieberman, Caroline Junqueira, and Ricardo T. Gazzinelli

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Sex and Gender Effects in Recovery From Alcohol Use Disorder, Cathryn Glanton Holzhauer, Michael Cucciare, and Elizabeth E. Epstein

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Improving stamina and mobility with preop walking in surgical patients with frailty traits -OASIS IV: randomized clinical trial study protocol, Laboni Hoque, Ryan Dewolf, David Meyers, Daniel K. White, Kathleen M. Mazor, Mihaela S. Stefan, Sybil L. Crawford, Karim Alavi, Jennifer K. Yates, Mark W. Maxfield, Feiran Lou, Karl Uy, J. Matthias Walz, and Alok Kapoor

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Cuffless Single-Site Photoplethysmography for Blood Pressure Monitoring, Manish Hosanee, Richard Fletcher, and Mohamed Elgendi

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The Lipid Handling Capacity of Subcutaneous Fat Is Programmed by mTORC2 during Development, Wen-Yu Hsiao, Su Myung Jung, Yuefeng Tang, John A. Haley, Rui Li, Huawei Li, Camila Martinez Calejman, Joan Sanchez-Gurmaches, Chien-Min Hung, Amelia K. Luciano, Victoria DeMambro, Kathryn E. Wellen, Clifford J. Rosen, Lihua Julie Zhu, and David A. Guertin

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Longitudinal biomarkers in amyotrophic lateral sclerosis, Fen Huang, Yuda Zhu, Jennifer Hsiao-Nakamoto, Xinyan Tang, Jason C. Dugas, Miriam Moscovitch-Lopatin, Jonathan D. Glass, Robert H. Brown Jr., Shafeeq S. Ladha, David Lacomis, Jeffrey M. Harris, Kimberly Scearce-Levie, Carole Ho, Robert Bowser, and James D. Berry

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Ribosome engineering reveals the importance of 5S rRNA autonomy for ribosome assembly, Shijie Huang, Nikolay A. Aleksashin, Anna B. Loveland, Dorota Klepacki, Kaspar Reier, Amira Kefi, Teresa Szal, Jaanus Remme, Luc Jaeger, Nora Vazquez-Laslop, Andrei A. Korostelev, and Alexander S. Mankin

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Generating Medical Assessments Using a Neural Network Model: Algorithm Development and Validation, Baotian Hu, Adarsha Bajracharya, and Hong Yu

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NCAPG Dynamically Coordinates the Myogenesis of Fetal Bovine Tissue by Adjusting Chromatin Accessibility, Xin Hu, Yishen Xing, Xing Fu, Qiyuan Yang, Ling Ren, Yahui Wang, Qian Li, Junya Li, and Lupei Zhang

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bta-miR-23a Regulates the Myogenic Differentiation of Fetal Bovine Skeletal Muscle-Derived Progenitor Cells by Targeting MDFIC Gene, Xin Hu, Yishen Xing, Ling Ren, Yahui Wang, Qian Li, Qiyuan Yang, Min Du, Lingyang Xu, Luc Willems, Junya Li, and Lupei Zhang

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A randomized, open-label, pragmatic study to assess reliever-triggered inhaled corticosteroid in African American/Black and Hispanic/Latinx adults with asthma: Design and methods of the PREPARE trial, Elliot Israel and M. Diane McKee

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Cost-effectiveness of Screening for Osteoporosis in Older Men With a History of Falls, Kouta Ito

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Structure of the Vesicular Stomatitis Virus L Protein in Complex with Its Phosphoprotein Cofactor, Simon Jenni, Louis-Marie Bloyet, Ruben Diaz-Avalos, Bo Liang, Sean P.J. Whelan, Nikolaus Grigorieff, and Stephen C. Harrison

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Chemical modifications of adenine base editor mRNA and guide RNA expand its application scope, Tingting Jiang, Xiao-Ou Zhang, Yueying Cao, Zhiping Weng, and Wen Xue

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Expanding Point-of-Care Ultrasound Training in a Low- and Middle-Income Country: Experiences From a Collaborative Short-Training Workshop in Kenya, Leanne Jones, Catherine Gathu, Daria Szkwarko, Sam Mucheru, Naushad Amin, James A. Amisi, Kevin Bergman, Mena Ramos, and Neil Jayasekera

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Examining Treatment Decision-Making Among Patients With Axial Spondyloarthritis: Insights From a Conjoint Analysis Survey, Woojin Joo, Christopher V. Almario, Mariko Ishimori, Yujin Park, Alma Jusufagic, Benjamin Noah, Lianne S. Gensler, R. Swamy Venuturupalli, Jonathan Kay, Michael H. Weisman, and Brennan M. R. Spiegel

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Preeclampsia knowledge among postpartum women treated for preeclampsia and eclampsia at Korle Bu Teaching Hospital in Accra, Ghana, Avina Joshi, Titus Beyuo, Samuel A. Oppong, Cheryl A. Moyer, and Emma R. Lawrence

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Gp41-targeted antibodies restore infectivity of a fusion-deficient HIV-1 envelope glycoprotein, Vinita R. Joshi, Ruchi M. Newman, Melissa L. Pack, Karen A. Power, James B. Munro, Ken Okawa, Navid Madani, Joseph G. Sodroski, Aaron G. Schmidt, and Todd M. Allen

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Objective Measurement of Physician Stress in the Emergency Department Using a Wearable Sensor, Eric E. Kaczor, Stephanie P. Carreiro, Joshua Stapp, Brittany P. Chapman, and Premananda Indic

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AMPA Receptor Auxiliary Subunit GSG1L Suppresses Short-Term Facilitation in Corticothalamic Synapses and Determines Seizure Susceptibility, Aichurok Kamalova, Kensuke Futai, Eric Delpire, and Terunaga Nakagawa

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Reducing Hospitalizations and Emergency Department Visits in Patients With Venous Thromboembolism Using a Multicomponent Care Transition Intervention, Alok Kapoor, Sarah Bloomstone, Saud Javed, Abiramy Maheswaran, Ahmed Nagy, Rasha Elhag, Diana Houng, Chad E. Darling, David D. McManus, Bruce A. Barton, and Kathleen M. Mazor

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Supplying Pharmacist Home Visit and Anticoagulation Professional Consultation During Transition of Care for Patients With Venous Thromboembolism, Alok Kapoor, Valentina Landyn, Joann L. Wagner, Pamela Burgwinkle, Wei Huang, Joel M. Gore, Frederick A. Spencer, Robert Goldberg, David D. McManus, Chad E. Darling, Edwin D. Boudreaux, Bruce A. Barton, and Kathleen M. Mazor

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Histone exchange is associated with activator function at transcribed promoters and with repression at histone loci, Sari Kassem, Paolo Ferrari, Amanda L. Hughes, Julien Soudet, Oliver J. Rando, and Michel Strubin

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Changes in selected haematological parameters associated with JAK1/JAK2 inhibition observed in patients with rheumatoid arthritis treated with baricitinib, Jonathan Kay, Masayoshi Harigai, Josh Rancourt, Christina Dickson, Thomas Melby, Maher Issa, Inmaculada de la Torre, Yoshitaka Isaka, Anabela Cardoso, Chadi Saifan, Edward C. Keystone, Ronald F. van Vollenhoven, Jon T. Giles, Tom Wj. Huizinga, and Joel M. Kremer

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M. tuberculosis Reprograms Hematopoietic Stem Cells to Limit Myelopoiesis and Impair Trained Immunity, Nargis Khan, Christopher M. Sassetti, and Maziar Divangahi

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Osteoblast-Osteoclast Communication and Bone Homeostasis, Jung-Min Kim, Chujiao Lin, Zheni Stavre, Matthew B. Greenblatt, and Jae-Hyuck Shim

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A RUNX2 stabilization pathway mediates physiologic and pathologic bone formation, Jung-Min Kim, Yeon-Suk Yang, Xianpeng Ge, Matthew B. Greenblatt, and Jae-Hyuck Shim

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Challenges and Lessons Learned From a Mobile Health, Web-Based Human Papillomavirus Intervention for Female Korean American College Students: Feasibility Experimental Study, Minjin Kim, Haeok Lee, and Jeroan J. Allison

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Predicting EQ-5D-5L crosswalk from the PROMIS-29 profile for the United Kingdom, France, and Germany, Christoph Paul Klapproth, J. van Bebber, C. J. Sidey-Gibbons, J. M. Valderas, A. Leplege, Matthias S. F. Rose, M. Rose, and F. Fischer

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PLCG2 protective variant p.P522R modulates tau pathology and disease progression in patients with mild cognitive impairment, Luca Kleineidam, Michael T. Heneka, and Alfredo Ramirez

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Deep gene sequence cluster analyses of multi-virus infected mucosal tissue reveal enhanced transmission of acute HIV-1, Katja Klein, Nicholas J. Hathaway, and Eric J. Arts

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Psychiatric illness and regression in individuals with Phelan-McDermid syndrome, Teresa M. Kohlenberg, M. Pilar Trelles, Brittany McLarney, Catalina Betancur, Audrey Thurm, and Alexander Kolevzon

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STRIDE-a fluorescence method for direct, specific in situ detection of individual single- or double-strand DNA breaks in fixed cells, Magdalena M. Kordon, Miroslaw Zarebski, Kamil Solarczyk, Hanhui Ma, Thoru Pederson, and Jurek W. Dobrucki

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Impact of Diabetes and Low Body Mass Index on Tuberculosis Treatment Outcomes, Hardy Kornfeld, Shruthi B. Sahukar, Elizabeth Procter-Gray, Nathella P. Kumar, Kim West, Kevin J. Kane, Mohan Natarajan, Wenjun Li, Subash Babu, and Vijay Viswanathan

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Hydroxychloroquine and the risk of respiratory infections among RA patients, Joel M. Kremer, George W. Reed, Dimitrios A. Pappas, Leslie R. Harrold, Kevin J. Kane, Jeffrey Greenberg, and Kevin Winthrop

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CRISPR deletion of the C9ORF72 promoter in ALS/FTD patient motor neurons abolishes production of dipeptide repeat proteins and rescues neurodegeneration, Gopinath Krishnan, Yu Zhang, Yuanzheng Gu, Mark W. Kankel, Fen-Biao Gao, and Sandra Almeida

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Learning curve in robotic transabdominal preperitoneal (rTAPP) ventral hernia repair: a cumulative sum (CUSUM) analysis, O. Y. Kudsi, F. Gokcal, N. Bou-Ayash, Allison S. Crawford, S. K. Chung, K. Chang, and Demetrius E. Litwin

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PAR1 (Protease-Activated Receptor 1) Pepducin Therapy Targeting Myocardial Necrosis in Coronary Artery Disease and Acute Coronary Syndrome Patients Undergoing Cardiac Catheterization: A Randomized, Placebo-Controlled, Phase 2 Study, Athan Kuliopulos, Paul A. Gurbel, Jeffrey J. Rade, Carey D. Kimmelstiel, Susan E. Turner, Kevin P. Bliden, Elizabeth K. Fletcher, Daniel H. Cox, and Lidija Covic

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Short-term e-cigarette vapour exposure causes vascular oxidative stress and dysfunction: evidence for a close connection to brain damage and a key role of the phagocytic NADPH oxidase (NOX-2), Marin Kuntic, John F. Keaney Jr., and Thomas Munzel

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Antibacterial Fusion Proteins Enhance Moraxella catarrhalis Killing, Maisem Laabei, Lucie Colineau, Serena Bettoni, Karolina Maziarz, David Ermert, Kristian Riesbeck, Sanjay Ram, and Anna M. Blom

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A Pilot Study of a Telemedicine-based Substance Use Disorder Evaluation to Enhance Access to Treatment Following Near-Fatal Opioid Overdose, Jeffrey T. Lai, Brittany P. Chapman, Stephanie P. Carreiro, Amy D. Costigan, Karla M. Rodriguez-Perez, Gerardo Gonzalez, and Kavita M. Babu

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Primary care physician perspectives on barriers to diagnosing axial Spondyloarthritis: a qualitative study, Kate L. Lapane, Sara Khan, Divya Shridharmurthy, Ariel Beccia, Catherine E. Dube, Esther Yi, Jonathan Kay, and Shao-Hsien Liu

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Metabolomic Profiling Reveals Distinct and Mutual Effects of Diet and Inflammation in Shaping Systemic Metabolism in Ldlr(-/-) Mice, Mario A. Lauterbach, Eicke Latz, and Anette Christ

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An improved zebrafish transcriptome annotation for sensitive and comprehensive detection of cell type-specific genes, Nathan D. Lawson, Rui Li, Masahiro Shin, Ann S. Grosse, Onur Yukselen, Oliver A. Stone, Alper Kucukural, and Lihua Julie Zhu