Open Access is free, unrestricted, online access to scientific and scholarly research. This collection includes Open Access journal articles authored by researchers, faculty, staff, and students of the University of Massachusetts Medical School.

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Publications from 2019

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The Influence of Different Fat Sources on Steatohepatitis and Fibrosis Development in the Western Diet Mouse Model of Non-alcoholic Steatohepatitis (NASH), Hannah K. Drescher, Ralf Weiskirchen, Annabelle Fulop, Carsten Hopf, Estibaliz Gonzalez de San Roman, Pitter F. Huesgen, Alain de Bruin, Laura Bongiovanni, Anette Christ, Rene Tolba, Christian Trautwein, and Daniela C. Kroy

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Comparing sensitivity to change using the 6-item versus the 17-item Hamilton depression rating scale in the GUIDED randomized controlled trial, Boadie W. Dunlop, Sagar V. Parikh, Anthony J. Rothschild, Michael E. Thase, Charles DeBattista, Charles R. Conway, Brent P. Forester, Francis M. Mondimore, Richard C. Shelton, Matthew Macaluso, Jennifer Logan, Paul Traxler, James Li, Holly Johnson, and John F. Greden

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An in-silico quality assurance study of contouring target volumes in thoracic tumors within a cooperative group setting, Hesham Elhalawani, Thomas J. Fitzgerald, Fran Laurie, Kenneth Ulin, Roy Decker, Charles R. Thomas Jr., and Clifton D. Fuller

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Differential Role of Pontomedullary Glutamatergic Neuronal Populations in Sleep-Wake Control, Evelyn T. M. Erickson, Loris L. Ferrari, Heinrich S. Gompf, and Christelle Anaclet

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A cross-sectional analysis of factors associated with detection of oncogenic human papillomavirus in human immunodeficiency virus-infected and uninfected Kenyan women, A. Ermel, P. Tonui, M. Titus, Y. Tong, N. Wong, J. Ong'echa, K. Muthoka, S. Kiptoo, Ann M. Moormann, J. Hogan, A. Mwangi, S. Cu-Uvin, P. J. Loehrer, O. Orang'o, and D. Brown

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The Molecular Basis of Human IgG-Mediated Enhancement of C4b-Binding Protein Recruitment to Group A Streptococcus, David Ermert, Maisem Laabei, Antonin Weckel, Matthias Morgelin, Martin Lundqvist, Lars Bjorck, Sanjay Ram, Sara Linse, and Anna M. Blom

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OR14I1 is a receptor for the human cytomegalovirus pentameric complex and defines viral epithelial cell tropism, Xiaofei E, Paul Meraner, Ping Lu, Jill M. Perreira, Aaron M. Aker, William M. McDougall, Ronghua Zhuge, Gary C. Chan, Rachel M. Gerstein, Patrizia Caposio, Andrew D. Yurochko, Abraham L. Brass, and Timothy F. Kowalik

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Methodology of an exercise intervention program using social incentives and gamification for obese children, Yue Fang, Yunsheng Ma, Dandan Mo, Shunxing Zhang, Mi Xiang, and Zhiruo Zhang

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GWAS for quantitative resistance phenotypes in Mycobacterium tuberculosis reveals resistance genes and regulatory regions, Maha R. Farhat, Luca Freschi, Roger Calderon, Thomas Ioerger, Matthew Snyder, Conor J. Meehan, Bouke de Jong, Leen Rigouts, Alexander Sloutsky, Devinder Kaur, Shamil Sunyaev, Dick van Soolingen, Jay Shendure, Jim Sacchettini, and Megan Murray

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Dissemination and Effectiveness of the Peer Marketing and Messaging of a Web-Assisted Tobacco Intervention: Protocol for a Hybrid Effectiveness Trial, Jamie Faro, Elizabeth Aaker Orvek, Amanda C. Blok, Catherine S. Nagawa, Annalise J. McDonald, Gregory Seward, Thomas K. Houston, Ariana Kamberi, Jeroan J. Allison, Sharina D. Person, Tina Grosowsky, and Rajani S. Sadasivam

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Proton pump inhibitors increase the severity of hepatic encephalopathy in cirrhotic patients, Matthew J. Fasullo, Prashanth Rau, Dong-Qi Liu, Erik Holzwanger, Jomol Mathew, Yurima Guilarte-Walker, and Gyongyi Szabo

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Multimodal quantitative imaging of brain cancer in cultured cells, Xin Feng, Alona Muzikansky, Alonzo H. Ross, Michael R. Hamblin, Peter R. Jermain, and Anna N. Yaroslavsky

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A data citation roadmap for scholarly data repositories, Martin Fenner, Merce Crosas, Jeffrey S. Grethe, David N. Kennedy, Henning Hermjakob, Phillippe Rocca-Serra, Gustavo Durand, Robin Berjon, Sebastian Karcher, Maryann Martone, and Tim Clark

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Advancing the implementation and sustainment of medication assisted treatment for opioid use disorders in prisons and jails, Warren J. Ferguson, Joan Johnston, Jennifer G. Clarke, Peter J. Koutoujian, Kathleen Maurer, Colleen Gallagher, Julie White, Dyana Nickl, and Faye S. Taxman

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Adipocyte ACLY Facilitates Dietary Carbohydrate Handling to Maintain Metabolic Homeostasis in Females, Sully Fernandez, John M. Viola, AnnMarie Torres, Martina Wallace, Sophie Trefely, Steven Zhao, Hayley C. Affronti, Jivani M. Gengatharan, David A. Guertin, Nathaniel W. Snyder, Christian M. Metallo, and Kathryn E. Wellen

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Outcomes and outcome measures used in evaluation of communication training in oncology - a systematic literature review, an expert workshop, and recommendations for future research, F. Fischer, S. Helmer, A. Rogge, J. I. Arraras, A. Buchholz, A. Hannawa, M. Horneber, A. Kiss, Matthias S. F. Rose, W. Sollner, B. Stein, J. Weis, P. Schofield, and C. M. Witt

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Minimal Associations Between Clinical Data and Children's Self-Reported Health-Related Quality of Life in Children With Chronic Conditions-A Cross-Sectional Study, Kathrin I. Fischer, Dana Barthel, Christiane Otto, Ulrike Ravens-Sieberer, Ute Thyen, Marcus Klein, Otto Walter, Matthias S. F. Rose, and Sandra Nolte

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Orbit image analysis machine learning software can be used for the histological quantification of acute ischemic stroke blood clots, Sean Fitzgerald, Shunli Wang, Daying Dai, Dennis H. Murphree Jr., Abhay Pandit, Andrew Douglas, Asim Rizvi, Ramanathan Kadirvel, Michael Gilvarry, Ray McCarthy, Manuel Stritt, Matthew J. Gounis, Waleed Brinjikji, David F. Kallmes, and Karen M. Doyle

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Coronary disease is not associated with robust alterations in inflammatory gene expression in human epicardial fat, Timothy P. Fitzgibbons, Nancy Lee, Khanh-Van T. Tran, Sarah M. Nicoloro, Mark Kelly, Stanley Kc Tam, and Michael P. Czech

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Positional transient loss of consciousness and hemispheric deficits in the setting of severe four-vessel extracranial cerebrovascular disease, Colleen P. Flanagan, Parth D. Sheth, and Jessica P. Simons

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Drosophila PSI controls circadian period and the phase of circadian behavior under temperature cycle via tim splicing, Lauren E. Foley, Jinli Ling, Radhika Sudhir Joshi, Naveh Evantal, Sebastian Kadener, and Patrick Emery

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Randomized trial of l-serine in patients with hereditary sensory and autonomic neuropathy type 1, Vera Fridman, Saranya Suriyanarayanan, Peter Novak, William David, Eric A. Macklin, Diane McKenna-Yasek, Kailey Walsh, Razina Aziz-Bose, Anne Louise Oaklander, Robert H. Brown Jr., Thorsten Hornemann, and Florian Eichler

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Structural organization of the C1a-e-c supercomplex within the ciliary central apparatus, Gang Fu, Lei Zhao, Erin Dymek, Yuqing Hou, Kangkang Song, Nhan Phan, Zhiguo Shang, Elizabeth F. Smith, George B. Witman, and Daniela Nicastro

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Aberrant splicing contributes to severe alpha-spectrin-linked congenital hemolytic anemia, Patrick G. Gallagher and Peter E. Newburger

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The emergence of pathogenic TNF/iNOS producing dendritic cells (Tip-DCs) in a malaria model of acute respiratory distress syndrome (ARDS) is dependent on CCR4, Bruno Galvao-Filho, Julia Teixeira de Castro, Maria Marta Figueiredo, Claudio Goncalves Rosmaninho, Lis Ribeiro do Valle Antonelli, and Ricardo T. Gazzinelli

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Anti-CRISPR AcrIIA5 Potently Inhibits All Cas9 Homologs Used for Genome Editing, Bianca Garcia, Jooyoung Lee, Alireza Edraki, Yurima Hidalgo-Reyes, Steven Erwood, Aamir Mir, Chantel N. Trost, Uri Seroussi, Sabrina Y. Stanley, Ronald D. Cohn, Julie M. Claycomb, Erik J. Sontheimer, Karen L. Maxwell, and Alan R. Davidson

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Effectiveness of integrative medicine group visits in chronic pain and depressive symptoms: A randomized controlled trial, Paula Gardiner, Man Luo, Salvatore D'Amico, Katherine Gergen-Barnett, Laura F. White, Robert Saper, Suzanne Mitchell, and Jane M. Liebschutz

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Anti-drug Antibody Responses Impair Prophylaxis Mediated by AAV-Delivered HIV-1 Broadly Neutralizing Antibodies, Matthew R. Gardner, Ina Fetzer, Lisa M. Kattenhorn, Meredith E. Davis-Gardner, Amber S. Zhou, Barnett Alfant, Jesse A. Weber, Hema R. Kondur, Jose M. Martinez-Navio, Sebastian P. Fuchs, Ronald C. Desrosiers, Guangping Gao, Jeffrey D. Lifson, and Michael Farzan

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The non-canonical SMC protein SmcHD1 antagonises TAD formation and compartmentalisation on the inactive X chromosome, Michal R. Gdula, Tatyana B. Nesterova, Greta Pintacuda, Jonathan Godwin, Ye Zhan, Hakan Ozadam, Michael McClellan, Daniella Moralli, Felix Krueger, Catherine M. Green, Wolf Reik, Skirmantas Kriaucionis, Edith Heard, Job Dekker, and Neil Brockdorff

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Single-Cell RNA-Sequencing-Based CRISPRi Screening Resolves Molecular Drivers of Early Human Endoderm Development, Ryan M. Genga, Eric M. Kernfeld, Krishna M. Parsi, Teagan J. Parsons, Michael J. Ziller, and Rene Maehr

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Modulation of actin polymerization affects nucleocytoplasmic transport in multiple forms of amyotrophic lateral sclerosis, Anthony Giampetruzzi, Eric W. Danielson, Valentina Gumina, Maryangel Jeon, Sivakumar Boopathy, Robert H. Brown Jr., Antonia Ratti, John E. Landers, and Claudia Fallini

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Citalopram in first episode schizophrenia: The DECIFER trial, Donald C. Goff and Xiaoduo Fan

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Comparison of bicarbonate values from venous blood gas and chemistry panels measured at the time of diagnosis and resolution of diabetes ketoacidosis, Poorani Nallam Goundan, Devina Luhur Willard, Ayse Sahin-Efe, Shu-Ling Liang Fan, and Sara Michelle Alexanian

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Comparison of a Potential Hospital Quality Metric With Existing Metrics for Surgical Quality-Associated Readmission, Laura A. Graham, Hillary J. Mull, Todd H. Wagner, Melanie S. Morris, Amy K. Rosen, Joshua S. Richman, Jeffery Whittle, Edith Burns, Laurel A. Copeland, Kamal M. F. Itani, and Mary T. Hawn

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Regulation of zebrafish melanocyte development by ligand-dependent BMP signaling, Alec Gramann, Arvind M. Venkatesan, Melissa Guerin, and Craig J. Ceol

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Impact of pharmacogenomics on clinical outcomes in major depressive disorder in the GUIDED trial: A large, patient- and rater-blinded, randomized, controlled study, John F. Greden and Anthony J. Rothschild

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Gene expression signature of atypical breast hyperplasia and regulation by SFRP1, Kelly J. Gregory, Giovanna M. Crisi, Brooke A. Bentley, Grace Makari-Judson, Holly S. Mason, Jun Yu, Lihua Julie Zhu, Karl J. Simin, Jacob P. S. Johnson, Ashraf Khan, Sallie S. Schneider, and D. Joseph Jerry

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Bridging from Intramuscular to Limb Perfusion Delivery of rAAV: Optimization in a Non-human Primate Study, Alisha Gruntman, Gwladys Gernoux, Qiushi Tang, Guo-Jie Ye, Dave R. Knop, Gensheng Wang, Janet Benson, Kristen E. Coleman, Allison M. Keeler, Christian Mueller, Louis G. Chicoine, Jeffrey D. Chulay, and Terence R. Flotte

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Perspectives of health educators and interviewers in a randomized controlled trial of a postpartum diabetes prevention program for Latinas: a qualitative assessment, Aline Gubrium, Denise Leckenby, Megan Ward Harvey, Bess H. Marcus, Milagros C. Rosal, and Lisa Chasan-Taber

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Complement alone drives efficacy of a chimeric antigonococcal monoclonal antibody, Sunita Gulati, Frank J. Beurskens, Bo Zheng, Rosane B. DeOliveira, Jutamas Shaughnessy, Nancy Nowak, Peter A. Rice, and Sanjay Ram

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Preclinical Efficacy of a Lipooligosaccharide Peptide Mimic Candidate Gonococcal Vaccine, Sunita Gulati, Michael W. Pennington, Andrzej Czerwinski, Darrick Carter, Bo Zheng, Nancy Nowak, Rosane B. DeOliveira, Jutamas Shaughnessy, George W. Reed, Sanjay Ram, and Peter A. Rice

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Targeting Lipooligosaccharide (LOS) for a Gonococcal Vaccine, Sunita Gulati, Jutamas Shaughnessy, Sanjay Ram, and Peter A. Rice

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Association Between Alcohol Use Disorders and Outcomes of Patients Hospitalized With Community-Acquired Pneumonia, Niyati M. Gupta, Peter K. Lindenauer, Pei-Chun Yu, Peter B. Imrey, Sarah Haessler, Abhishek Deshpande, Thomas L. Higgins, and Michael B. Rothberg

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Chromatin profiling of cortical neurons identifies individual epigenetic signatures in schizophrenia, Fedor E. Gusev, Denis A. Reshetov, Amanda C. Mitchell, Tatiana V. Andreeva, Aslihan Dincer, Anastasia P. Grigorenko, Gennady Fedonin, Tobias Halene, Maria Aliseychik, Elena Filippova, Zhiping Weng, Schahram Akbarian, and Evgeny I. Rogaev

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Human islets expressing HNF1A variant have defective beta cell transcriptional regulatory networks, Rachana Haliyur, Sambra D. Redick, David M. Harlan, and Alvin C. Powers

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Transfer RNA Genes Affect Chromosome Structure and Function via Local Effects, Omar Hamdani, Tsung-Han S. Hsieh, Oliver J. Rando, and Rohinton T. Kamakaka

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Less iatrogenic soft-tissue damage utilizing robotic-assisted total knee arthroplasty when compared with a manual approach: A blinded assessment, Emily L. Hampp, Nipun Sodhi, Laura Scholl, Matthew E. Deren, Zachary Yenna, Geoffrey Westrich, and Michael A. Mont

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Streptolysin O Induces the Ubiquitination and Degradation of Pro-IL-1beta, Dora Hancz, Elsa Westerlund, Christine Valfridsson, Getachew Melkamu Aemero, Benedicte Bastiat-Sempe, M. Pontus A. Orning, Egil Lien, Michael R. Wessels, and Jenny J. Persson

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Selection of an Efficient AAV Vector for Robust CNS Transgene Expression, Killian S. Hanlon, Miguel Sena-Esteves, Eloise Hudry, and Casey A. Maguire

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Alzheimer's Disease Microbiome Is Associated with Dysregulation of the Anti-Inflammatory P-Glycoprotein Pathway, John P. Haran, Shakti K. Bhattarai, Sage Foley, Protiva Dutta, Doyle V. Ward, Vanni Bucci, and Beth A. McCormick

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Serum Deprivation of Mesenchymal Stem Cells Improves Exosome Activity and Alters Lipid and Protein Composition, Reka A. Haraszti, Rachael Miller, Michelle L. Dubuke, Andrew H. Coles, Marie C. Didiot, Dimas Echeverria, Matteo Stoppato, Yves Y. Sere, John D. Leszyk, Julia F. Alterman, Bruno M. D. C. Godinho, Matthew R. Hassler, Rachel Wollacott, Yan Wang, Scott A. Shaffer, Neil Aronin, and Anastasia Khvorova

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Lipoprotein(a) plasma levels, bone mineral density and risk of hip fracture: a post hoc analysis of the Women's Health Initiative, USA, Bernhard Haring, Carolyn J. Crandall, Laura Carbone, Simin Liu, Wenjun Li, Karen C. Johnson, Jean Wactawski-Wende, Aladdin H. Shadyab, Margery L. Gass, Victor Kamensky, Jane A. Cauley, and Sylvia Wassertheil-Smoller

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Early pre-radiographic structural pathology precedes the onset of accelerated knee osteoarthritis, Matthew S. Harkey, Julie E. Davis, Bing Lu, Lori Lyn Price, Robert J. Ward, James W. MacKay, Charles B. Eaton, Grace H. Lo, Mary F. Barbe, Ming Zhang, Jincheng Pang, Alina C. Stout, Timothy E. McAlindon, and Jeffrey B. Driban

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Long-term, Real-world Safety of Adalimumab in Rheumatoid Arthritis: Analysis of a Prospective US-Based Registry, Leslie R. Harrold, Jenny Griffith, Patrick Zueger, Heather J. Litman, Bernice Gershenson, Syed S. Islam, Christine J. Barr, Dianlin Guo, Jonathan Fay, and Jeffrey D. Greenberg

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Patellar Tendon Reconstruction Using Semitendinosus Autograft With Preserved Distal Insertion for Treatment of Patellar Tendon Rupture After Bone-Patellar Tendon-Bone ACL Reconstruction: A Case Report, John P. Haskoor and Brian D. Busconi

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Becoming Doctors: Examining Student Narratives to Understand the Process of Professional Identity Formation Within a Learning Community, David S. Hatem and Thomas Halpin

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Modeling of Cisplatin-Induced Signaling Dynamics in Triple-Negative Breast Cancer Cells Reveals Mediators of Sensitivity, Anne Margriet Heijink, Marieke Everts, Megan E. Honeywell, Ryan Richards, Yannick P. Kok, Elisabeth G. E. de Vries, Michael J. Lee, and Marcel A T M van Vugt

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The neutrophil-to-lymphocyte and monocyte-to-lymphocyte ratios are independently associated with neurological disability and brain atrophy in multiple sclerosis, Christopher C. Hemond, Bonnie I. Glanz, Rohit Bakshi, Tanuja Chitnis, and Brian C. Healy

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Barriers and Facilitators to Genetic Testing for Familial Hypercholesterolemia in the United States: A Review, Rachele M. Hendricks-Sturrup, Kathleen M. Mazor, Amy C. Sturm, and Christine Y. Lu

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Alternative splicing regulates stochastic NLRP3 activity, Florian Hoss, James L. Mueller, Francisca Rojas Ringeling, Juan F. Rodriguez-Alcazar, Rebecca Brinkschulte, Gerald Seifert, Rainer Stahl, Lori Broderick, Chris D. Putnam, Richard D. Kolodner, Stefan Canzar, Matthias Geyer, Hal M. Hoffman, and Eicke Latz

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Gain-of-function mutations in the UNC-2/CaV2alpha channel lead to excitation-dominant synaptic transmission in C. elegans, Yung-Chi Huang, Jennifer K. Pirri, Diego Rayes, Shangbang Gao, Ben Mulcahy, Jeff Grant, Yasunori Saheki, Michael M. Francis, Mei Zhen, and Mark J. Alkema

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A Receptor of the Immunoglobulin Superfamily Regulates Adaptive Thermogenesis, Carmen Hurtado Del Pozo, Randall H. Friedline, Hye Lim Noh, Jason K. Kim, and Ann Marie. Schmidt

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Consensus statement from the International Consensus Meeting on the Role of Decompressive Craniectomy in the Management of Traumatic Brain Injury : Consensus statement, Peter J. Hutchinson and Susanne Muehlschlegel

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Bta-miR-24-3p Controls the Myogenic Differentiation and Proliferation of Fetal, Bovine, Skeletal Muscle-Derived Progenitor Cells by Targeting ACVR1B, Xin Hu, Yishen Xing, Ling Ren, Yahui Wang, Qian Li, Xing Fu, Qiyuan Yang, Lingyang Xu, Luc Willems, Junya Li, and Lupei Zhang

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Preformulation Characterization and Stability Assessments of Secretory IgA Monoclonal Antibodies as Potential Candidates for Passive Immunization by Oral Administration, Yue Hu, Ozan S. Kumru, Jian Xiong, Lorena R. Antunez, John Hickey, Yang Wang, Lisa Cavacini, Mark S. Klempner, Sangeeta B. Joshi, and David B. Volkin

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Suppressing Aneuploidy-Associated Phenotypes Improves the Fitness of Trisomy 21 Cells, Sunyoung Hwang, Jessica F. Williams, Maja Kneissig, Maria Lioudyno, Isabel Rivera, Pablo Helguera, Jorge Busciglio, Zuzana Storchova, Megan C. King, and Eduardo M. Torres

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A Comprehensive Review of Pegvaliase, an Enzyme Substitution Therapy for the Treatment of Phenylketonuria, Tasmina Hydery and Valerie Azzopardi Coppenrath

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Genome-Scale CRISPR Screens Identify Human Pluripotency-Specific Genes, Robert J. Ihry, Zinger Yang, and Ajamete Kaykas

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Regulation of nuclear-cytoplasmic partitioning by the lin-28-lin-46 pathway reinforces microRNA repression of HBL-1 to confer robust cell-fate progression in C. elegans, Orkan Ilbay and Victor R. Ambros

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How best to assess cough as an outcome measure, Richard S. Irwin and Cynthia L. French

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Pneumococcal epidemiology among us adults hospitalized for community-acquired pneumonia, Raul E. Isturiz, Julio Ramirez, Wesley H. Self, Carlos G. Grijalva, Francis L. Counselman, Gregory A. Volturo, Luis Ostrosky-Zeichner, Paula Peyrani, Richard G. Wunderink, Robert Sherwin, J. Scott Overcash, Senen Pena Oliva, Thomas File, Timothy L. Wiemken, John M. McLaughlin, Michael W. Pride, Sharon Gray, Ronika Alexander, Kimbal D. Ford, Qin Jiang, and Luis Jodar

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In situ Structure of Rotavirus VP1 RNA-Dependent RNA Polymerase, Simon Jenni, Eric N. Salgado, Tobias Herrmann, Zongli Li, Timothy Grant, Nikolaus Grigorieff, Stefano Trapani, Leandro F. Estrozi, and Stephen C. Harrison

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In vivo clonal expansion and phenotypes of hypocretin-specific CD4(+) T cells in narcolepsy patients and controls, Wei Jiang, James R. Birtley, Grant C. Weaver, Liying Lu, Lawrence J. Stern, and Elizabeth D. Mellins

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Natural HIV-1 Nef Polymorphisms Impair SERINC5 Downregulation Activity, Steven W. Jin, Nirmin Alsahafi, Xiaomei T. Kuang, Shayda A. Swann, Mako Toyoda, Heinrich G. Gottlinger, Bruce D. Walker, Takamasa Ueno, Andres Finzi, Zabrina L. Brumme, and Mark A. Brockman

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Automatic Detection of Hypoglycemic Events From the Electronic Health Record Notes of Diabetes Patients: Empirical Study, Yonghao Jin, Fei Li, Varsha G. Vimalananda, and Hong Yu

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Wake Forest University long-term follow-up of type 2 myocardial infarction: The Wake-Up T2MI Registry, Hanumantha R. Jogu and Waqas Qureshi

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5-HT2A deletion protects against Clozapine-induced hyperglycemia, Radhika Sudhir Joshi, Shishu Pal Singh, and Mitradas M. Panicker

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A permethrin metabolite is associated with adaptive immune responses in Gulf War Illness, Utsav Joshi, Lawrence J. Stern, and Laila Abdullah

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Leptin induces cell migration and invasion in a FAK-Src- dependent manner in breast cancer cells, Juan Carlos Juarez-Cruz, Miriam Daniela. Zuniga-Eulogio, Monserrat Olea-Flores, Eduardo Castaneda-Saucedo, Miguel Angel. Mendoza-Catalan, Carlos Ortuno-Pineda, Ma Elena. Moreno-Godinez, Socrates Villegas-Comonfort, Teresita Padilla-Benavides, and Napoleon Navarro-Tito

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High-resolution cryo-EM structures of outbreak strain human norovirus shells reveal size variations, James Jung, Timothy Grant, Dennis R. Thomas, Chris W. Diehnelt, Nikolaus Grigorieff, and Leemor Joshua-Tor

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CDR3alpha drives selection of the immunodominant Epstein Barr virus (EBV) BRLF1-specific CD8 T cell receptor repertoire in primary infection, Larisa Kamga, Anna Gil, InYoung Song, Robin M. Brody, Dario Ghersi, Nuray Aslan, Lawrence J. Stern, Liisa K. Selin, and Katherine Luzuriaga

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Orbital Atherectomy for Calcific Coronary Artery Disease in Patients With Severe Aortic Stenosis: A Safety and Feasibility Study, Ibrahim Kassas, Ahmed Nagy, Alvaro Alonso, Mohammed W. Akhter, Craig Smith, Mohamed Ahmed, Abdul Moiz Hafiz, Jennifer Walker, and Nikolaos Kakouros

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Everything Matters: The ReproNim Perspective on Reproducible Neuroimaging, David N. Kennedy, Julianna F. Bates, Christian Haselgrove, and Steven M. Hodge

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Candida albicans Factor H Binding Molecule Hgt1p - A Low Glucose-Induced Transmembrane Protein Is Trafficked to the Cell Wall and Impairs Phagocytosis and Killing by Human Neutrophils, Samyr Kenno, Cornelia Speth, Gunter Rambach, Ulrike Binder, Sneha Chatterjee, Rita Caramalho, Hubertus Haas, Cornelia Lass-Florl, Jutamas Shaughnessy, Sanjay Ram, Neil A.R. Gow, Dorothea Orth-Holler, and Reinhard Wurzner

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Functional Analysis of DNMT3A DNA Methyltransferase Mutations Reported in Patients with Acute Myeloid Leukemia, Daria A. Khrabrova, Andrei G. Loiko, Anastasia A. Tolkacheva, Natalia A. Cherepanova, Maria I. Zvereva, Olga V. Kirsanova, and Elizaveta S. Gromova

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Systems approach reveals photosensitivity and PER2 level as determinants of clock-modulator efficacy, Dae Wook Kim, Cheng Chang, Xian Chen, Angela C. Doran, Francois Gaudreault, Travis Wager, George J. DeMarco, and Jae Kyoung Kim

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The ERK MAPK Pathway Is Essential for Skeletal Development and Homeostasis, Jung-Min Kim, Yeon-Suk Yang, Kwang Hwan Park, Hwanhee Oh, Matthew B. Greenblatt, and Jae-Hyuck Shim

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The institutional repository landscape in medical schools and academic health centers: a 2018 snapshot view and analysis, Daniel G. Kipnis, Lisa A. Palmer, and Ramune K. Kubilius

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Selective inhibition of N-linked glycosylation impairs receptor tyrosine kinase processing, Elsenoor Klaver, Peng Zhao, Melanie May, Heather Flanagan-Steet, Hudson H. Freeze, Reid Gilmore, Lance Wells, Joseph Contessa, and Richard Steet

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Regulation of the Drosophila Imd pathway by signaling amyloids, Anni Kleino and Neal S. Silverman

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Proteomics Profiling and Risk of New-Onset Atrial Fibrillation: Framingham Heart Study, Darae Ko, Mark D. Benson, Debby Ngo, Qiong Yang, Martin G. Larson, Thomas J. Wang, Ludovic Trinquart, David D. McManus, Steven A. Lubitz, Patrick T. Ellinor, Ramachandran S. Vasan, Robert E. Gerszten, Emelia J. Benjamin, and Honghuang Lin

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The role of platelets in mediating a response to human influenza infection, Milka Koupenova-Zamor, Heather A. Corkrey, Olga Vitseva, Giorgia Manni, Catherine J. Pang, Lauren Clancy, Chen Yao, Jeffrey J. Rade, Daniel Levy, Jennifer P. Wang, Robert W. Finberg, Evelyn A. Kurt-Jones, and Jane E. Freedman

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Pollen-derived RNAs Are Found in the Human Circulation, Milka Koupenova-Zamor, Eric O. Mick, Heather A. Corkrey, Anupama Singh, Selim E. Tanriverdi, Olga Vitseva, Daniel Levy, Allison M. Keeler, Marzieh Ezzaty Mirhashemi, Mai K. Elmallah, Mark Gerstein, Joel Rozowsky, Kahraman Tanriverdi, and Jane E. Freedman

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A small peptide antagonist of the Fas receptor inhibits neuroinflammation and prevents axon degeneration and retinal ganglion cell death in an inducible mouse model of glaucoma, Anitha Krishnan, Andrew J. Kocab, David N. Zacks, Ann Marshak-Rothstein, and Meredith Gregory-Ksander

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Pharmacological inhibition of the NLRP3 inflammasome reduces blood pressure, renal damage, and dysfunction in salt-sensitive hypertension, Shalini M. Krishnan, Eicke Latz, and Grant R. Drummond

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DEBrowser: interactive differential expression analysis and visualization tool for count data, Alper Kucukural, Onur Yukselen, Deniz M. Ozata, Melissa J. Moore, and Manuel Garber

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Durability of symptomatic responses obtained with adjunctive vagus nerve stimulation in treatment-resistant depression, Arun Kumar, Mark T. Bunker, Scott T. Aaronson, Charles R. Conway, Anthony J. Rothschild, Giacomo Mordenti, and Augustus J. Rush

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Persistent inflammation during anti-tuberculosis treatment with diabetes comorbidity, Nathella Pavan Kumar, Kiyoshi F. Fukutani, Basavaradhya S. Shruthi, Thabata Alves, Paulo S. Silveira-Mattos, Michael S. Rocha, Kim West, Mohan Natarajan, Vijay Viswanathan, Subash Babu, Bruno B. Andrade, and Hardy Kornfeld

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Systemic RAGE ligands are upregulated in tuberculosis individuals with diabetes co-morbidity and modulated by anti-tuberculosis treatment and metformin therapy, Nathella Pavan Kumar, Kadar Moideen, Arul Nancy, Vijay Viswanathan, Basavaradhya S. Shruthi, Shanmugam Sivakumar, Syed Hissar, Hardy Kornfeld, and Subash Babu

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Plasma chemokines are biomarkers of disease severity, higher bacterial burden and delayed sputum culture conversion in pulmonary tuberculosis, Nathella P. Kumar, Kadar Moideen, Arul Nancy, Vijay Viswanathan, Basavaradhya S. Shruthi, Shanmugam Sivakumar, Mohan Natarajan, Hardy Kornfeld, and Subash Babu