Open Access is free, unrestricted, online access to scientific and scholarly research. This collection includes Open Access journal articles and other materials authored by researchers, faculty, staff, and students of the University of Massachusetts Medical School.

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Publications from 2020

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International observational atopic dermatitis cohort to follow natural history and treatment course: TARGET-DERM AD study design and rationale, Katrina Abuabara, Jonathan I. Silverberg, Eric L. Simpson, Amy S. Paller, Lawrence F. Eichenfield, Robert Bissonnette, James Krueger, John E. Harris, Laura Dalfonso, Stephanie E. Watkins, Julie M. Crawford, D. Thaci, and Emma Guttman-Yassky

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Modified CHA2DS2-VASc score predicts in-hospital mortality and procedural complications in acute coronary syndrome treated with percutaneous coronary intervention, Ashraf Abugroun, Abdalla Hassan, Safwan Gaznabi, Hakeem Ayinde, Ahmed Subahi, Mohammed Samee, Adhir Shroff, and Lloyd W. Klein

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Multimorbidity, physical frailty, and self-rated health in older patients with atrial fibrillation, Hawa Ozien Abu, Jane Saczynski, Jordy Mehawej, Tenes Paul, Hamza Awad, Benita A. Bamgbade, Isabelle C. Pierre-Louis, Mayra Tisminetzky, Catarina I. Kiefe, Robert J. Goldberg, and David D. McManus

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Clinically Meaningful Change in Quality of Life and Associated Factors Among Older Patients With Atrial Fibrillation, Hawa Ozien Abu, Jane S. Saczynski, Jordy Mehawej, Mayra Tisminetzky, Catarina I. Kiefe, Robert J. Goldberg, and David D. McManus

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The long non-coding RNA LUCAT1 is a negative feedback regulator of interferon responses in humans, Shiuli Agarwal, Tim Vierbuchen, Sreya Ghosh, Jennie Chan, Zhaozhao Jiang, Richard K. Kandasamy, Emiliano Ricci, and Katherine A. Fitzgerald

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Long Non-coding RNA LincRNA-EPS Inhibits Host Defense Against Listeria monocytogenes Infection, Federica Agliano, Katherine A. Fitzgerald, Anthony T. Vella, Vijay A. Rathinam, and Andrei E. Medvedev

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RNA Therapeutics Are Stepping Out of the Maze, Sudhir Agrawal

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Origami-Inspired Approaches for Biomedical Applications, Abdor Rahman Ahmed, Olivia C. Gauntlett, and Gulden Camci-Unal

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Inherent regulatory asymmetry emanating from network architecture in a prevalent autoregulatory motif, Zulfikar Ali, Vinuselvi Parisutham, Sandeep Choubey, and Robert C. Brewster

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A conserved myotubularin-related phosphatase regulates autophagy by maintaining autophagic flux, Elizabeth A. Allen, Clelia Amato, Tina M. Fortier, Panagiotis D. Velentzas, Will Wood, and Eric H. Baehrecke

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Interchangeability of Biosimilars: What Level of Clinical Evidence is Needed to Support the Interchangeability Designation in the United States, Daniel F. Alvarez, Gertjan Wolbink, Carol Cronenberger, John Orazem, and Jonathan Kay

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Transiently "Undead" Enterocytes Mediate Homeostatic Tissue Turnover in the Adult Drosophila Midgut, Alla Amcheslavsky, Jillian L. Lindblad, and Andreas Bergmann

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Immunometabolism in Caenorhabditis elegans, Sarah M. Anderson and Read Pukkila-Worley

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Dipeptide repeat proteins inhibit homology-directed DNA double strand break repair in C9ORF72 ALS/FTD, Nadja S. Andrade, Abbas Abdallah, Christian Mueller, and Zane Zeier

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In-Vitro Sorbent-Mediated Removal of Edoxaban from Human Plasma and Albumin Solution, Alexandra A. Angheloiu, Yanglan Tan, Cristian Ruse, Scott A. Shaffer, and George O. Angheloiu

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Luteinizing Hormone Action in Human Oocyte Maturation and Quality: Signaling Pathways, Regulation, and Clinical Impact, Armando Arroyo, Beomsu Kim, and John Yeh

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Declines in Lung Function After Antiretroviral Therapy Initiation in Adults With Human Immunodeficiency Virus and Tuberculosis: A Potential Manifestation of Respiratory Immune Reconstitution Inflammatory Syndrome, Sara C. Auld, Pholo Maenetje, Shruthi Ravimohan, Drew Weissman, Itai Ncube, Mandla Mlotshwa, Nelly Ratsela, William Chase, Mboyo-Di-Tamba Vangu, Robert Wallis, Gavin Churchyard, Hardy Kornfeld, and Gregory P. Bisson

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Skp, Cullin, F-box (SCF)-Met30 and SCF-Cdc4-Mediated Proteolysis of CENP-A Prevents Mislocalization of CENP-A for Chromosomal Stability in Budding Yeast, Wei-Chun Au, Richard E. Baker, and Munira A. Basrai

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A Unique Presentation of Cutaneous Diffuse Large B-Cell Lymphoma, Mary Awad, Erik Holzwanger, and Sandeep Jubbal

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FANCJ compensates for RAP80 deficiency and suppresses genomic instability induced by interstrand cross-links, Sanket Awate, Joshua A. Sommers, Arindam Datta, Sumeet Nayak, Marina A. Bellani, Olivia Yang, Christopher A. Dunn, Claudia M. Nicolae, George-Lucian Moldovan, Michael M. Seidman, Sharon B. Cantor, and Robert M. Brosh

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Estimation in meta-analyses of response ratios, Ilyas Bakbergenuly, David C. Hoaglin, and Elena Kulinskaya

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Psychosocial and cognitive multimorbidity and health-related quality of life and symptom burden in older adults with atrial fibrillation: The systematic assessment of geriatric elements in atrial fibrillation (SAGE-AF) cohort study, Benita A. Bamgbade, Saket Sanghai, David D. McManus, Darleen M. Lessard, Molly E. Waring, Sarah N. Forrester, Isabelle Pierre-Louis, and Jane S. Saczynski

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Two cases of acute anterolateral compartment syndrome following inversion ankle injuries, Jugert Bango, Evan Zhang, Daniel Aaron, and Amna Diwan

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Editorial: Macrophages in Liver Disease, Ruchi Bansal, Pranoti Mandrekar, Sujit K. Mohanty, and Ralf Weiskirchen

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mRNA stem-loops can pause the ribosome by hindering A-site tRNA binding, Chen Bao, Sarah Loerch, Clarence Ling, Andrei A. Korostelev, Nikolaus Grigorieff, and Dmitri N. Ermolenko

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Pulmonary Edema: A Pictorial Review of Imaging Manifestations and Current Understanding of Mechanisms of Disease, Maria Barile

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Tumor cell-organized fibronectin maintenance of a dormant breast cancer population, Lauren E. Barney, Christopher L. Hall, Alyssa D. Schwartz, Akia N. Parks, Christopher Sparages, Sualyneth Galarza, Manu O. Platt, Arthur M. Mercurio, and Shelly R. Peyton

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Translating research into practice: Protocol for a community-engaged, stepped wedge randomized trial to reduce disparities in breast cancer treatment through a regional patient navigation collaborative, Tracy A. Battaglia, Karen M. Freund, Jennifer S. Haas, Nicole Casanova, Sharon Bak, Howard Cabral, Rachel A. Freedman, Karen Burns. White, and Stephenie C. Lemon

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Distinct Bacterial Pathways Influence the Efficacy of Antibiotics against Mycobacterium tuberculosis, Michelle Bellerose, Megan K. Proulx, Clare M. Smith, Richard E. Baker, Thomas R. Ioerger, and Christopher M. Sassetti

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Body mass index and treatment survival in patients with RA starting treatment with TNFalpha-inhibitors: long-term follow-up in the real-life METEOR registry, Sytske Anne Bergstra, Cornelia F. Allaart, David Vega-Morales, Marieke De Buck, Elizabeth Murphy, Karen I. Salomon-Escoto, and Tom W. J. Huizinga

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Investigating Socioeconomic Disparities in the Potential Healthy Eating and Physical Activity Environments of Churches, John A. Bernhart, Elizabeth A. La Valley, Andrew T. Kaczynski, Sara Wilcox, Danielle E. Jake-Schoffman, Nathan Peters, Caroline G. Dunn, and Brent Hutto

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An Interactive Web-Based Lethal Means Safety Decision Aid for Suicidal Adults (Lock to Live): Pilot Randomized Controlled Trial, Marian E. Betz, Christopher E. Knoepke, Scott Simpson, Bonnie J. Siry, Ashley Clement, Tamara Saunders, Rachel Johnson, Deborah Azrael, Edwin D. Boudreaux, Faris Omeragic, Leah M. Adams, Sydney Almond, Elizabeth Juarez-Colunga, and Daniel D. Matlock

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Assessment of Hypertension Using Clinical Electrocardiogram Features: A First-Ever Review, Kathleen Bird, Gabriel Chan, Huiqi Lu, Heloise Greeff, John Allen, Derek Abbott, Carlo Menon, Nigel H. Lovell, Newton Howard, Wee-Shian Chan, Richard Ribon Fletcher, Aymen Alian, Rabab Ward, and Mohamed Elgendi

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The chemical structure and phosphorothioate content of hydrophobically modified siRNAs impact extrahepatic distribution and efficacy, Annabelle Biscans, Jillian Caiazzi, Sarah M. Davis, Nicholas McHugh, Jacquelyn Sousa, and Anastasia Khvorova

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Docosanoic acid conjugation to siRNA enables functional and safe delivery to skeletal and cardiac muscles, Annabelle Biscans, Jillian Caiazzi, Nicholas McHugh, Vignesh Hariharan, Manish Muhuri, and Anastasia Khvorova

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Benefits and harms of high-dose haemodiafiltration versus high-flux haemodialysis: the comparison of high-dose haemodiafiltration with high-flux haemodialysis (CONVINCE) trial protocol, Peter J. Blankestijn, Kathrin I. Fischer, Claudia Barth, Krister Cromm, Bernard Canaud, Andrew Davenport, Diederick E. Grobbee, Jorgen Hegbrant, Kit C. Roes, Matthias S. F. Rose, Giovanni Fm. Strippoli, Robin Wm. Vernooij, Mark Woodward, G. Ardine de Wit de, and Michiel L. Bots

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Access and Continuity: A Multidisciplinary Education Workshop to Teach Patient-Centered Medical Home (PCMH) Principles, Lauren Block, Christopher Petersen, Daniel J. Coletti, Pratiksha Yalakkishettar, and Nancy LaVine

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Linearized Siderophore Products Secreted via MacAB Efflux Pump Protect Salmonella enterica Serovar Typhimurium from Oxidative Stress, L M. Bogomolnaya, Ronak Tilvawala, J. R. Elfenbein, J. D. Cirillo, and H. L. Andrews-Polymenis

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Metformin enhances anti-mycobacterial responses by educating CD8+ T-cell immunometabolic circuits, Julia Bohme, Nuria Martinez, Hardy Kornfeld, and Amit Singhal

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MEKK2 mediates aberrant ERK activation in neurofibromatosis type I, Seoyeon Bok, Dong Yeon Shin, Alisha R. Yallowitz, Mark Eiseman, Michelle Cung, Ren Xu, Na Li, Jun Sun, Alfred L. Williams, John E. Scott, Bing Su, Jae-Hyuck Shim, and Matthew B. Greenblatt

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Upregulating beta-hexosaminidase activity in rodents prevents alpha-synuclein lipid associations and protects dopaminergic neurons from alpha-synuclein-mediated neurotoxicity, Oeystein R. Brekk, Joanna A. Korecka, Cecile C. Crapart, Mylene Huebecker, Zachary K. MacBain, Sara Ann Rosenthal, Miguel Sena-Esteves, David A. Priestman, Frances M. Platt, Ole Isacson, and Penelope J. Hallett

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HOX paralogs selectively convert binding of ubiquitous transcription factors into tissue-specific patterns of enhancer activation, Laure Bridoux, Peyman Zarrineh, Joshua Mallen, Mike Phuycharoen, Victor Latorre, Frank Ladam, Marta Losa, Syed Murtuza Baker, Charles G. Sagerstrom, Kimberly A. Mace, Magnus Rattray, and Nicoletta Bobola

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Clustering of strong replicators associated with active promoters is sufficient to establish an early-replicating domain, Caroline Brossas, Anne-Laure Valton, Sergey V. Venev, Sabarinadh Chilaka, Antonin Counillon, Marc Laurent, Coralie Goncalves, Benedicte Duriez, Franck Picard, Job Dekker, and Marie-Noelle Prioleau

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Acidic pH Triggers Lipid Mixing Mediated by Lassa Virus GP, Uriel Bulow, Ramesh Govindan, and James B. Munro

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Evaluation of Noninvasive Respiratory Volume Monitoring in the PACU of a Low Resource Kenyan Hospital, Kendall Burdick, Muchai Stephen Thuo, Xiaoke Sarah Feng, Matthew S. Shotwell, and Joseph J. Schlesinger

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The impact of a randomized controlled trial of a lifestyle intervention on postpartum physical activity among at-risk hispanic women: Estudio PARTO, Sarah Burkart, Bess H. Marcus, Penelope Pekow, Milagros C. Rosal, JoAnn E. Manson, Barry Braun, and Lisa Chasan-Taber

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A classification model of homelessness using integrated administrative data: Implications for targeting interventions to improve the housing status, health and well-being of a highly vulnerable population, Thomas Byrne, Travis Baggett, Thomas Land, Dana Bernson, Maria-Elena Hood, Cheryl Kennedy-Perez, Rodrigo Monterrey, David A. Smelson, Marc Dones, and Monica Bharel

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mTORC2-AKT signaling to ATP-citrate lyase drives brown adipogenesis and de novo lipogenesis, Camila Martinez Calejman, S. Trefely, S. W. Entwisle, Amelia K. Luciano, Su Myung. Jung, Wen-Yu Hsiao, A. Torres, C. M. Hung, H. Li, N. W. Snyder, J. Villen, K. E. Wellen, and David A. Guertin

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Meta-analyses of ataluren randomized controlled trials in nonsense mutation Duchenne muscular dystrophy, Craig Campbell and Brenda L. Wong

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Burden of disease from COVID-19 and its acute and chronic complications: reflections on measurement (DALYs) and prospects for the Brazilian Unified National Health System, Monica Rodrigues. Campos, Joyce Mendes de Andrade Schramm, Isabel Cristina Martins Emmerick, Jessica Muzy Rodrigues, Fernando Genovez de Avelar, and Thiago Goes Pimentel

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ArfB can displace mRNA to rescue stalled ribosomes, Christine E. Carbone, Gabriel Demo, Rohini Madireddy, Egor Svidritskiy, and Andrei A. Korostelev

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Integrated miRNA-/mRNA-Seq of the Habenulo-Interpeduncular Circuit During Acute Nicotine Withdrawal, Alison P. Casserly, Junko Tsuji, Rubing Zhao-Shea, Ciearra B. Smith, Susanna Molas-Casacuberta, Andrew R. Tapper, Zhiping Weng, and Paul D. Gardner

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Association of subclinical atherosclerosis with echocardiographic indices of cardiac remodeling: The Framingham Study, Cecilia Castro-Diehl, Rebecca J. Song, Gary F. Mitchell, David D. McManus, Susan Cheng, Ramachandran S. Vasan, and Vanessa Xanthakis

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Racial/Ethnic Disparities in Physical Function Before and After Total Knee Arthroplasty Among Women in the United States, Alyson M. Cavanaugh, Mitchell J. Rauh, Caroline A. Thompson, John Alcaraz, William M. Mihalko, Chloe E. Bird, Giselle Corbie-Smith, Milagros C. Rosal, Wenjun Li, Aladdin H. Shadyab, Todd Gilmer, and Andrea Z. LaCroix

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Natural history study of glycan accumulation in large animal models of GM2 gangliosidoses, Catlyn Cavender, Linley Mangini, Jeremy L. Van Vleet, Carley Corado, Emma McCullagh, Heather L. Gray-Edwards, Douglas R. Martin, Brett E. Crawford, and Roger Lawrence

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Roles of Adipokines in Digestive Diseases: Markers of Inflammation, Metabolic Alteration and Disease Progression, Ming-Ling Chang, Zinger Yang, and Sien-Sing Yang

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A Cas9 with PAM recognition for adenine dinucleotides, Pranam Chatterjee, Jooyoung Lee, Lisa Nip, Sabrina R. T. Koseki, Emma Tysinger, Erik J. Sontheimer, Joseph M. Jacobson, and Noah Jakimo

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Combining Citizen Science and Genomics to Investigate Tick, Pathogen, and Commensal Microbiome at Single-Tick Resolution, Gaurav Chauhan, Jesse McClure, Jessica Hekman, Patrick W. Marsh, Jeffrey A. Bailey, Rachel F. Daniels, Diane P. Genereux, and Elinor K. Karlsson

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Altered photoreceptor metabolism in mouse causes late stage age-related macular degeneration-like pathologies, Shun-Yun Cheng, Joris Cipi, Shan Ma, Brian P. Hafler, Rahul N. Kanadia, Richard S. Brush, Martin-Paul Agbaga, and Claudio Punzo

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The Snakeskin-Mesh Complex of Smooth Septate Junction Restricts Yorkie to Regulate Intestinal Homeostasis in Drosophila, Hsi-Ju Chen, Qi Li, Niraj K. Nirala, and Y. Tony Ip

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Prevention of mitochondrial impairment by inhibition of protein phosphatase 1 activity in amyotrophic lateral sclerosis, So Yoen Choi, Ju-Hyun Lee, Ah-Young Chung, Youhwa Jo, Joo-Ho Shin, Hae-Chul Park, Hyun Kim, Rodrigo Lopez-Gonzalez, Jae Ryun Ryu, and Woong Sun

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National Survey of Burnout and Distress among Cardiothoracic Surgery Trainees, Oliver S. Chow, Monisha Sudarshan, Mark W. Maxfield, Laura M. Seese, Ammara A. Watkins, Aaron Fleishman, and Sidhu P. Gangadharan

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Characterization of viral insulins reveals white adipose tissue-specific effects in mice, Martina Chrudinova, Francois Moreau, Hye Lim Noh, Terezie Panikova, Lenka Zakova, Randall H. Friedline, Francisco A. Valenzuela, Jason K. Kim, Jiri Jiracek, C. Ronald Kahn, and Emrah Altindis

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The Rose-Colored Glasses of Geriatric Fall Patients: Inconsistencies Between Knowledge of Risk Factors for and Actual Causes of Falls, Courtney E. Collins, Arnav Chandra, Bryan Nguyen, Kurt Schultz, Pawan Mathew, Tiffany Chen, Savannah Renshaw, Karen M. Rose, and Heena P. Santry

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Improving patient-provider communication about chronic pain: development and feasibility testing of a shared decision-making tool, Nananda Col, Stephen Hull, Vicky Springmann, Long Ngo, Ernie Merritt, Susan Gold, Michael Sprintz, Noel Genova, Noah Nesin, Brenda Tierman, Frank Sanfilippo, Richard Entel, and Lori Pbert

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Leveraging Implementation Science to Understand Factors Influencing Sustained Use of Mental Health Apps: a Narrative Review, Samantha L. Connolly, Timothy P. Hogan, Stephanie L. Shimada, and Christopher J. Miller

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A big-data approach to understanding metabolic rate and response to obesity in laboratory mice, June K. Corrigan, Deepti Ramachandran, Yuchen He, Colin J. Palmer, Michael J. Jurczak, Rui Chen, Bingshan Li, Randall H. Friedline, Jason K. Kim, Jon J. Ramsey, Louise Lantier, Owen P. McGuinness, and Alexander S. Banks

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Diffusion rather than intraflagellar transport likely provides most of the tubulin required for axonemal assembly in Chlamydomonas, Julie Craft Van De Weghe, J. Aaron Harris, Tomohiro Kubo, George B. Witman, and Karl F. Lechtreck

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Neutrophil infiltration regulates clock-gene expression to organize daily hepatic metabolism, Maria Crespo, Norman J. Kennedy, Roger J. Davis, Nuria Matesanz, Magdalena Leiva, and Guadalupe Sabio

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Ubiquitous neurocognitive dysfunction in familial adenomatous polyposis: proof-of-concept of the role of APC protein in neurocognitive function, Marcia Roxana Cruz-Correa, Ana Cecilia Sala, Beatriz Cintron, Jessica Hernandez, Myrta Olivera, Adrian Cora, Constance M. Moore, Carlos A. Luciano, Marievelisse Soto-Salgado, Francis M. Giardiello, and Stephen R. Hooper

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Comparisons of Antibody Populations in Different Pre-Fusion F VLP-Immunized Cotton Rat Dams and Their Offspring, Lori McGinnes Cullen, Marina S. Boukhvalova, Jorge C. G. Blanco, and Trudy G. Morrison

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Compilation and Analysis of Web-Based Orthopedic Personalized Predictive Tools: A Scoping Review, Patrick Curtin, Alexandra Conway, Liu Martin, Eugenia Lin, Prakash Jayakumar, and Eric F. Swart

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Mechanisms of insulin resistance related to white, beige, and brown adipocytes, Michael P. Czech

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Tacrolimus- and sirolimus-induced human beta cell dysfunction is reversible and preventable, Chunhua Dai, John T. Walker, Alena Shostak, Ana Padgett, Erick Spears, Scott Wisniewski, Greg Poffenberger, Radhika Aramandla, E Danielle. Dean, Nripesh Prasad, Shawn E. Levy, Dale L. Greiner, Leonard D. Shultz, Rita Bottino, and Alvin C. Powers

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Conformational changes in the Ebola virus membrane fusion machine induced by pH, Ca2+, and receptor binding, Dibyendu Kumar Das, Uriel Bulow, William E. Diehl, Natasha D. Durham, Fernando Senjobe, Kartik Chandran, Jeremy Luban, and James B. Munro

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The relationship between physical activity and lymphoma: a systematic review and meta analysis, Gwynivere A. Davies, Christopher Strader, Richa Chibbar, Stefania Papatheodorou, and Adam A. Dmytriw

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2'-O-Methyl at 20-mer Guide Strand 3' Termini May Negatively Affect Target Silencing Activity of Fully Chemically Modified siRNA, Sarah M. Davis, Jacquelyn Sousa, Lorenc Vangjeli, Matthew R. Hassler, Dimas Echeverria, Emily G. Knox, Anton A. Turanov, Julia F. Alterman, and Anastasia Khvorova

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Bifidobacterium infantis Metabolizes 2'Fucosyllactose-Derived and Free Fucose Through a Common Catabolic Pathway Resulting in 1,2-Propanediol Secretion, Liv R. Dedon, Ezgi Ozcan, Asha Rani, and David A. Sela

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Pneumoconiosis, Navina DeLight and Howard J. Sachs

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Assessing invasiveness of subsolid lung adenocarcinomas with combined attenuation and geometric feature models, Constance de Margerie-Mellon, Ritu R. Gill, Pascal Salazar, Anastasia Oikonomou, Elsie T. Nguyen, Benedikt H. Heidinger, Mayra A. Medina, Paul A. VanderLaan, and Alexander A. Bankier

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Human endogenous retrovirus HERV-K(HML-2) RNA causes neurodegeneration through Toll-like receptors, Paul Dembny, Douglas T. Golenbock, and Seija Lehnardt

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BCL11A enhancer edited hematopoietic stem cells persist in rhesus monkeys without toxicity, Selami Demirci, Jing Zeng, Yuxuan Wu, Naoya Uchida, Anne H. Shen, Danilo Pellin, Jackson Gamer, Morgan Yapundich, Claire Drysdale, Jasmine Bonanno, Aylin C. Bonifacino, Allen Krouse, Nathaniel Seth. Linde, Theresa Engels, Robert E. Donahue, Juan J. Haro-Mora, Alexis Leonard, Tina Nassehi, Kevin Luk, Shaina N. Porter, Cicera R. Lazzarotto, Shengdar Q. Tsai, Mitchell Weiss, Shondra M. Pruett-Miller, Scot A. Wolfe, Daniel E. Bauer, and John F. Tisdale

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Infectious disease outbreaks among forcibly displaced persons: an analysis of ProMED reports 1996-2016, Angel N. Desai, John W. Ramatowski, Nina Marano, Lawrence C. Madoff, and Britta Lassmann

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Basement membrane damage by ROS- and JNK-mediated Mmp2 activation drives macrophage recruitment to overgrown tissue, Neha Diwanji and Andreas Bergmann

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Flexible Usage and Interconnectivity of Diverse Cell Death Pathways Protect against Intracellular Infection, Marcel Doerflinger, Milton Pereira, Andreas Strasser, Sammy Bedoui, and Marco J. Herold

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Risk factors and the natural history of accelerated knee osteoarthritis: a narrative review, Jeffrey B. Driban, Matthew S. Harkey, Mary F. Barbe, Robert J. Ward, James W. MacKay, Julie E. Davis, Bing Lu, Lori Lyn Price, Charles B. Eaton, Grace H. Lo, and Timothy E. McAlindon

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Prevalence of Pain on Admission by Level of Cognitive Impairment in Nursing Homes, Catherine E. Dube, Reynolds A. Morrison, Deborah Mack, William M. Jesdale, Anthony P. Nunes, Shao-Hsien Liu, and Kate L. Lapane

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Real-Time Analysis of Individual Ebola Virus Glycoproteins Reveals Pre-Fusion, Entry-Relevant Conformational Dynamics, Natasha D. Durham, Angela R. Howard, Ramesh Govindan, Fernando Senjobe, J. Maximilian Fels, William E. Diehl, Jeremy Luban, Kartik Chandran, and James B. Munro

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Psychiatric Symptomatology, Mood Regulation, and Resting State Functional Connectivity of the Amygdala: Preliminary Findings in Youth With Mood Disorders and Childhood Trauma, Yael Dvir, David N. Kennedy, Steven M. Hodge, Destiny Pegram, Brian Denietolis, and Jean A. Frazier

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YAP1/TAZ drives ependymoma-like tumour formation in mice, Noreen Eder, Federico Roncaroli, Marie-Charlotte Dolmart, Stuart Horswell, Felipe Andreiuolo, Helen R. Flynn, Andre T. Lopes, Suzanne Claxton, John-Paul Kilday, Lucy Collinson, Junhao Mao, Torsten Pietsch, Barry Thompson, Ambrosius P. Snijders, and Sila K. Ultanir

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Case Series: Gene Expression Analysis in Canine Vogt-Koyanagi-Harada/Uveodermatologic Syndrome and Vitiligo Reveals Conserved Immunopathogenesis Pathways Between Dog and Human Autoimmune Pigmentary Disorders, Ista A. Egbeto, Colton J. Garelli, Cesar Piedra-Mora, Neil B. Wong, Clement N. David, Nicholas A. Robinson, and Jillian M. Richmond

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Dbf4-Dependent Kinase (DDK)-Mediated Proteolysis of CENP-A Prevents Mislocalization of CENP-A in Saccharomyces cerevisiae, Jessica R. Eisenstatt, Lars Boeckmann, Wei-Chun Au, Valerie Garcia, Levi Bursch, Josefina Ocampo, Michael Costanzo, Michael Weinreich, Robert A. Sclafani, Anastasia Baryshnikova, Chad L. Myers, Charles Boone, David J. Clark, Richard E. Baker, and Munira A. Basrai

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Diagnostic Category Prevalence in 3 Classification Systems Across the Transition to the International Classification of Diseases, Tenth Revision, Clinical Modification, Randall P. Ellis, Heather E. Hsu, Chenlu Song, Tzu-Chun Kuo, Bruno Martins, Jeffrey J. Siracuse, Ying Liu, and Arlene S. Ash

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A chromosomal connectome for psychiatric and metabolic risk variants in adult dopaminergic neurons, Sergio Espeso-Gil, Tyler M. Borrman, Zhiping Weng, and Schahram Akbarian

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Bifurcations and the Emergence of L2 Syntactic Structures in a Complex Dynamic System, D. Reid Evans and Diane Larsen-Freeman

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Dopamine transporter trafficking and Rit2 GTPase: Mechanism of action and in vivo impact, Rita R. Fagan, Patrick Kearney, Carolyn G. Sweeney, Dino Luethi, Florianne E. Schoot Uiterkamp, Klaus Schicker, Brian S. Alejandro, Lauren C. O'Connor, Harald H. Sitte, and Haley Melikian

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Transcriptomics of Gabra4 knockout mice reveals common NMDAR pathways underlying autism, memory, and epilepsy, Cuixia Fan, Yue Gao, Guanmei Liang, Lang Huang, Jing Wang, Xiaoxue Yang, Yiwu Shi, Ursula C. Drager, Mei Zhong, Tian-Ming Gao, and Xinping Yang

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Comparison of a Collective Intelligence Tailored Messaging System on Smoking Cessation Between African American and White People Who Smoke: Quasi-Experimental Design, Jamie Faro, Catherine S. Nagawa, Jeroan J. Allison, Stephenie C. Lemon, Kathleen M. Mazor, Thomas K. Houston, and Rajani S. Sadasivam

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Diabetes mellitus type 2 is associated with increased tumor expression of programmed death-ligand 1 (PD-L1) in surgically resected non-small cell lung cancer - A matched case-control study, Christopher A. Febres-Aldana, Robert Poppiti, John M. Varlotto, Rick Voland, Michael Zaleski, Setareh Sharzehi, and Negar Rassaei

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Simultaneous epigenetic perturbation and genome imaging reveal distinct roles of H3K9me3 in chromatin architecture and transcription, Ying Feng, Yao Wang, Xiangnan Wang, Xiaohui He, Chen Yang, Ardalan Naseri, Thoru Pederson, Jing Zheng, Shaojie Zhang, Xiao Xiao, Wei Xie, and Hanhui Ma