Open Access is free, unrestricted, online access to scientific and scholarly research. This collection includes Open Access journal articles authored by researchers, faculty, staff, and students of the University of Massachusetts Medical School.

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Publications from 2020

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Adenine base editing in an adult mouse model of tyrosinaemia, Chun-Qing Song, Tingting Jiang, Michelle Richter, Luke H. Rhym, Luke W. Koblan, Maria Paz Zafra, Emma M. Schatoff, Jordan L. Doman, Yueying Cao, Lukas E. Dow, Lihua Julie Zhu, Daniel G. Anderson, David R. Liu, Hao Yin, and Wen Xue

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Neonatal-derived IL-17 producing dermal gammadelta T cells are required to prevent spontaneous atopic dermatitis, Nicholas A. Spidale, Nidhi Malhotra, Michela Frascoli, Katelyn E. Sylvia, Bing Miu, Coral Freeman, Brian D. Stadinski, Eric Huseby, and Joonso Kang

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Canine Models of Inherited Musculoskeletal and Neurodegenerative Diseases, Brett D. Story, Matthew E. Miller, Allison M. Bradbury, Emily D. Million, Dongsheng Duan, Toloo Taghian, Dominik Faissler, Deborah Fernau, Sidney J. Beecy, and Heather Gray-Edwards

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Branched-chain alpha-ketoacid dehydrogenase deficiency (maple syrup urine disease): Treatment, biomarkers, and outcomes, Kevin A. Strauss

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Humanity's Best Friend: A Dog-Centric Approach to Addressing Global Challenges, Naomi Sykes, Elinor K. Karlsson, and Greger Larson

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Hypercholesterolemia Accelerates the Aging Phenotypes of Hematopoietic Stem Cells by a Tet1-Dependent Pathway, Guodong Tie, Jinglian Yan, Lyne Khair, Amanda A. Tutto, and Louis M. Messina

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Myosin Sequestration Regulates Sarcomere Function, Cardiomyocyte Energetics, and Metabolism, Informing the Pathogenesis of Hypertrophic Cardiomyopathy, Christopher N. Toepfer, Raul Padron, and Christine E. Seidman

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Gender Identity and Sexual Orientation Identity in Women and Men Prenatally Exposed to Diethylstilbestrol, Rebecca Troisi, Julie R. Palmer, Elizabeth E. Hatch, William C. Strohsnitter, Dezheng Huo, Marianne Hyer, Karen I. Fredriksen-Goldsen, Robert Hoover, and Linda Titus

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Peptidylarginine Deiminase Isozyme-Specific PAD2, PAD3 and PAD4 Inhibitors Differentially Modulate Extracellular Vesicle Signatures and Cell Invasion in Two Glioblastoma Multiforme Cell Lines, Pinar Uysal-Onganer, Amy MacLatchy, Rayan Mahmoud, Igor Kraev, Paul R. Thompson, Jameel M. Inal, and Sigrun Lange

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Airway epithelial specific deletion of Jun-N-terminal kinase 1 attenuates pulmonary fibrosis in two independent mouse models, Jos L. van der Velden, John F. Alcorn, David G. Chapman, Lennart K. A. Lundblad, Charles G. Irvin, Roger J. Davis, Kelly Butnor, and Yvonne M. W. Janssen-Heininger

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Characterizing Patients with Recurrent Urinary Tract Infections in Vesicoureteral Reflux: A Pilot Study of the Urinary Proteome, Dijana Vitko, Patricia Cho, Stephen A. Kostel, Shannon E. DiMartino, Lily D. Cabour, Matthew A. Migliozzi, Tanya Logvinenko, Peter G. Warren, John W. Froehlich, and Richard S. Lee

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Exogenous GDF11, but not GDF8, reduces body weight and improves glucose homeostasis in mice, Ryan G. Walker, Hye Lim Noh, Taekyoon Kim, Jason K. Kim, and Richard T. Lee

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Frequent mutation of hypoxia-related genes in persistent pulmonary hypertension of the newborn, Mingbang Wang, Deyi Zhuang, Mei Mei, Haiyan Ma, Zixiu Li, Fusheng He, Guoqiang Cheng, Guang Lin, and Wenhao Zhou

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Glycan profiles of gp120 protein vaccines from four major HIV-1 subtypes produced from different host cell lines under non-GMP or GMP conditions, Shixia Wang, Yegor Voronin, Peng Zhao, Mayumi Ishihara, Nickita Mehta, Mindy Porterfield, Yuxin Chen, Christopher Bartley, Guangnan Hu, Dong Han, Lance Wells, Michael Tiemeyer, and Shan Lu

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Methylation of SRD5A2 promoter predicts a better outcome for castration-resistant prostate cancer patients undergoing androgen deprivation therapy, Zongwei Wang, Tuo Deng, Xingbo Long, Xueming Lin, Shulin Wu, Hongbo Wang, Rongbin Ge, Zhenwei Zhang, Chin-Lee Wu, Mary-Ellen Taplin, and Aria F. Olumi

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Intensity and frequency of physical activity and high blood pressure in adolescents: A longitudinal study, Robert J. Wellman, Marie-Pierre Sylvestre, Patrick Abi Nader, Arnaud Chiolero, Miceline Mesidor, Erika N. Dugas, Gauthier Tougri, and Jennifer O'Loughlin

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Multimodal Photoplethysmography-Based Approaches for Improved Detection of Hypertension, Kaylie Welykholowa, Richard Fletcher, and Mohamed Elgendi

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Combining genomics and epidemiology to track mumps virus transmission in the United States, Shirlee Wohl, Lawrence C. Madoff, and Bronwyn L. MacInnis

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The Cancer Microbiome: Distinguishing Direct and Indirect Effects Requires a Systemic View, Joao B. Xavier and Amir Mitchell

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DolphinNext: a distributed data processing platform for high throughput genomics, Onur Yukselen, Osman Turkyilmaz, Ahmet R. Ozturk, Manuel Garber, and Alper Kucukural

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Comprehensive identification of alternative back-splicing in human tissue transcriptomes, Peng Zhang, Xiao-Ou Zhang, Tingting Jiang, Lingling Cai, Xiao Huang, Qi Liu, Dan Li, Aiping Lu, Yan Liu, Wen Xue, Peng Zhang, and Zhiping Weng

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Development of an early-warning system for high-risk patients for suicide attempt using deep learning and electronic health records, Le Zheng, Alex N. Sabo, Liliana Markovic, and Xuefeng B. Ling

Publications from 2019

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A novel vaccine platform using glucan particles for induction of protective responses against Francisella tularensis and other pathogens, Ambily Abraham, Gary R. Ostroff, Stuart M. Levitz, and P. C. F. Oyston

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TRACE-CORE Dataset on Religious Practices and Long-Term Survival after Hospital Discharge for an Acute Coronary Syndrome, Hawa O. Abu, Kate L. Lapane, Molly E. Waring, Christine M. Ulbricht, Randolph S. Devereaux, David D. McManus, Jeroan J. Allison, Catarina I. Kiefe, and Robert J. Goldberg

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Religious practices and long-term survival after hospital discharge for an acute coronary syndrome, Hawa Ozien Abu, Kate L. Lapane, Molly E. Waring, Christine M. Ulbricht, Randolph S. Devereaux, David D. McManus, Jeroan J. Allison, Catarina I. Kiefe, and Robert J. Goldberg

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Religious practices and changes in health-related quality of life after hospital discharge for an acute coronary syndrome, Hawa Ozien Abu, David D. McManus, Darleen M. Lessard, Catarina I. Kiefe, and Robert J. Goldberg

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Prevalence, trends, outcomes, and disparities in hospitalizations for nonalcoholic fatty liver disease in the United States, Adeyinka Adejumo, Gbeminiyi Olanrewaju Samuel, Oluwole Muyiwa Adegbala, Kelechi Lauretta. Adejumo, Ogooluwa Ojelabi, Olalekan Akanbi, Olumuyiwa Akinbolaji Ogundipe, and Lydie Pani

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Transformation Support Provided Remotely to a National Cohort of Optometry Practices, Ronald N. Adler, Warren J. Ferguson, Hussein Antar, Michael Steinkrauss, Brian Bjoern, Valerie Konar, Jay Flanagan, and David F. Polakoff

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Segmental Distribution of Hepatocellular Carcinoma Correlates with Microvascular Invasion in Liver Explants Undergoing Transplantation, Yasir Al-Azzawai, Eva Rouanet, Ryan J. Hendrix, Lidia Spaho, Hesham Malik, Deepika Devuni, Gyongyi Szabo, and Graham Barnard

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Comparative Pangenomics of the Mammalian Gut Commensal Bifidobacterium longum, Korin Albert, Asha Rani, and David Sela

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Changes in Anticoagulant Utilization Among United States Nursing Home Residents With Atrial Fibrillation From 2011 to 2016, Matthew Alcusky, David D. McManus, Anne L. Hume, Marc Fisher, Jennifer Tjia, and Kate L. Lapane

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Production of poly(GA) in C9ORF72 patient motor neurons derived from induced pluripotent stem cells, Sandra Almeida, Gopinath Krishnan, Mia Rushe, Yuanzheng Gu, Mark W. Kankel, and Fen-Biao Gao

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Receptor interacting protein kinase 3 (RIP3) regulates iPSCs generation through modulating cell cycle progression genes, Ahmad Al-Moujahed, Bo Tian, Nikolaos E. Efstathiou, Eleni K. Konstantinou, Mien Hoang, Haijiang Lin, Joan W. Miller, and Demetrios G. Vavvas

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Carotid body tumor resection utilizing a covered stent graft to enable resection of the tumor en bloc with the internal carotid artery, Mohammad Alqaim, Ajit S. Puri, Alec E. Vaezi, and Andres Schanzer

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Compartmentalization of Immune Response and Microbial Translocation in Decompensated Cirrhosis, Camila Alvarez-Silva, Robert Schierwagen, Alessandra Pohlmann, Fernando Magdaleno, Frank E. Uschner, Patrick Ryan, Maria J.G.T. Vehreschild, Joan Claria, Eicke Latz, Benjamin Lelouvier, Manimozhiyan Arumugam, and Jonel Trebicka

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Use of Electronic Health Record Access and Audit Logs to Identify Physician Actions Following Noninterruptive Alert Opening: Descriptive Study, Azraa Amroze, Terry S. Field, Hassan Fouayzi, Devi Sundaresan, Laura Burns, Lawrence Garber, Rajani S. Sadasivam, Kathleen M. Mazor, Jerry H. Gurwitz, and Sarah L. Cutrona

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The fatty acid oleate is required for innate immune activation and pathogen defense in Caenorhabditis elegans, Sarah M. Anderson, Hilary K. Cheesman, Nicholas D. Peterson, Elisabeth B. Salisbury, Alexander A. Soukas, and Read Pukkila-Worley

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Complement Targets Newborn Retinal Ganglion Cells for Phagocytic Elimination by Microglia, Sarah R. Anderson, Jianmin Zhang, Michael R. Steele, Cesar O. Romero, Amanda G. Kautzman, Dorothy P. Schafer, and Monica L. Vetter

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Psychosocial, psychiatric and work-related risk factors associated with suicide in Ireland: optimised methodological approach of a case-control psychological autopsy study, E. Arensman and Celine Larkin

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Social Media Use and HIV Screening Uptake Among Deaf Adults in the United States: Cross-Sectional Survey Study, Michael Argenyi and Poorna Kushalnagar

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Use and Outcomes Associated With Perioperative Amiodarone in Cardiac Surgery, Auras R. Atreya, Aruna Priya, Quinn R. Pack, Penelope S. Pekow, Mihaela Stefan, Tara Lagu, Amir S. Lotfi, and Peter K. Lindenauer

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Ninjurin1 positively regulates osteoclast development by enhancing the survival of prefusion osteoclasts, Sung-Jin Bae, Min Wook Shin, Taekwon Son, Hye Shin. Lee, Ji Soo Chae, Sejin Jeon, Goo Taeg Oh, and Kyu-Won Kim

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Extracellular Vesicles in Liver Diseases: Meeting Report from the International Liver Congress 2018, Jesus M. Banales, Ariel E. Feldstein, Hanna Sanger, Veronika Lukacs-Kornek, Gyongyi Szabo, and Miroslaw Kornek

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Atrial Fibrillation Detection from Wrist Photoplethysmography Signals Using Smartwatches, Syed Khairul Bashar, Dong Han, Shirin Hajeb-Mohammadalipour, Eric Y. Ding, Cody Whitcomb, David D. McManus, and Ki H. Chon

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Multi-dimensional Transcriptional Remodeling by Physiological Insulin In Vivo, Thiago M. Batista, Ruben Garcia-Martin, Weikang Cai, Masahiro Konishi, Brian T. O'Neill, Masaji Sakaguchi, Jong Hun Kim, Dae Young Jung, Jason K. Kim, and C. Ronald Kahn

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A Disintegrin and Metalloproteinase 9 Domain (ADAM9) Is a Major Susceptibility Factor in the Early Stages of Encephalomyocarditis Virus Infection, Lindsey E. Bazzone, Michael King, Christopher R. MacKay, Pyae Phyo Kyawe, Paul Meraner, Daniel Lindstrom, Joselyn Rojas-Quintero, Caroline A. Owen, Jennifer P. Wang, Abraham L. Brass, Evelyn A. Kurt-Jones, and Robert W. Finberg

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A Meningococcal Outer Membrane Vesicle Vaccine with Overexpressed Mutant FHbp Elicits Higher Protective Antibody Responses in Infant Rhesus Macaques than a Licensed Serogroup B Vaccine, Peter T. Beernink, Vianca Vianzon, Lisa A. Lewis, Gregory R. Moe, and Dan M. Granoff

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Common Variants in the Glycerol Kinase Gene Reduce Tuberculosis Drug Efficacy, Michelle M. Bellerose, Seung-Hun Baek, Chuan-Chin Huang, Caitlin E. Moss, Eun-Ik Koh, Megan K. Proulx, Clare M. Smith, Richard E. Baker, Jong Seok Lee, Seokyong Eum, Sung Jae Shin, Sang-Nae Cho, Megan Murray, and Christopher M. Sassetti

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Brazilian generics market change after Farmacia Popular program, Andrea Damaso Bertoldi, Luisa Arueira Chaves, Dennis Ross-Degnan, Vera Lucia Luiza, Isabel Cristina Martins Emmerick, Rondineli Mendes da Silva, and Monica Rodrigues. Campos

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The Brazilian private pharmaceutical market after the first ten years of the generics law, Andrea Damaso Bertoldi, Anita K. Wagner, Isabel Emmerick, Luisa Arueira Chaves, Peter Stephens, and Dennis Ross-Degnan

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Using Electronic Referrals to Address Health Disparities and Improve Blood Pressure Control, Amy Bettano, Thomas Land, Alice Byrd, Susan Svencer, and Laura Nasuti

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C4BP-IgM protein as a therapeutic approach to treat Neisseria gonorrhoeae infections, Serena Bettoni, Jutamas Shaughnessy, Karolina Maziarz, David Ermert, Sunita Gulati, Bo Zheng, Matthias Morgelin, Susanne Jacobsson, Kristian Riesbeck, Magnus Unemo, Sanjay Ram, and Anna M. Blom

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Intersectional effects of racial and gender discrimination on cardiovascular health vary among black and white women and men in the CARDIA study, Ganga S. Bey, William M. Jesdale, Sarah N. Forrester, Sharina D. Person, and Catarina I. Kiefe

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Still Disease, Juhi Bhargava and Sreelakshmi Panginikkod

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Single cell transcriptomic profiling of large intestinal enteroendocrine cells in mice - Identification of selective stimuli for insulin-like peptide-5 and glucagon-like peptide-1 co-expressing cells, Lawrence J. Billing, Pierre Larraufie, Jo Lewis, Andrew B. Leiter, Joyce H. Li, Brian Lam, Giles Sh. Yeo, Deborah A. Goldspink, Richard G. Kay, Fiona M. Gribble, and Frank Reimann

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Inactivating mutations and X-ray crystal structure of the tumor suppressor OPCML reveal cancer-associated functions, James R. Birtley, Zachary Maben, Grant C. Weaver, Mollie M. Jurewicz, Lawrence J. Stern, Chiara Recchi, and Hani Gabra

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Diverse lipid conjugates for functional extra-hepatic siRNA delivery in vivo, Annabelle Biscans, Andrew H. Coles, Reka A. Haraszti, Dimas Echeverria, Matthew R. Hassler, Maire F. Osborn, and Anastasia Khvorova

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Nurse-Driven mHealth Implementation Using the Technology Inpatient Program for Smokers (TIPS): Mixed Methods Study, Amanda C. Blok, Rajani S. Sadasivam, Timothy P. Hogan, Angela Patterson, Nicole Day, and Thomas K. Houston

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Neighborhood Characteristics and Colorectal Cancer Survivors' Quality of Care, Ulrike Boehmer, Jennifer Potter, Melissa A. Clark, Al Ozonoff, Rachel M. Ceballos, Michael Winter, and Kevan L. Hartshorn

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Design and methods of the Healthy Kids and Families study: a parent-focused community health worker-delivered childhood obesity prevention intervention, Amy Borg, Christina F. Haughton, Mullen Sawyer, Stephenie C. Lemon, Kevin J. Kane, Lori Pbert, Wenjun Li, and Milagros C. Rosal

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Common Nodes of Virus-Host Interaction Revealed Through an Integrated Network Analysis, Korbinian Bosl and Richard K. Kandasamy

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Gait mechanics contribute to exercise induced pain flares in knee osteoarthritis, Katherine A. Boyer and Jocelyn F. Hafer

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Proton pump inhibitors and 180-day mortality in the elderly after Clostridium difficile treatment, Evan S. Bradley, Emily Howe, Xun Wu, and John P. Haran

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Investigating Potential Biomarkers in Autism Spectrum Disorder, Carolyn Bridgemohan, David E. Cochran, Andrew W. Zimmerman, Roula N. Choueiri, and Jean A. Frazier

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Comparison of artifacts between paste and collodion method of electrode application in pediatric EEG, Danielle Brigham, Yash Shah, Kanwaljit Singh, Ivan Pavkovic, Shefali Karkare, and Sanjeev V. Kothare

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A Persistence Detector for Metabolic Network Rewiring in an Animal, Jote T. Bulcha, Gabrielle E. Giese, Zulfikar Ali, Yong-Uk Lee, Melissa D. Walker, Amy D. Holdorf, L. Safak Yilmaz, Robert C. Brewster, and Albertha J. M. Walhout

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Clinical Molecular Marker Testing Data Capture to Promote Precision Medicine Research Within the Cancer Research Network, Andrea N. Burnett-Hartman and Mara M. Epstein

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One-year survival and admission to hospital for cardiovascular events among older residents of long-term care facilities who were prescribed intensive- and moderate-dose statins, Michael A. Campitelli, Colleen J. Maxwell, Laura C. Maclagan, Dennis T. Ko, Chaim M. Bell, Lianne Jeffs, Andrew M. Morris, Kate L. Lapane, Nick Daneman, and Susan E. Bronskill

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Diapause induces functional axonal regeneration after necrotic insult in C. elegans, Mauricio Caneo, Victoria Julian, Alexandra B. Byrne, Mark J. Alkema, and Andrea Calixto

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Solenodon genome reveals convergent evolution of venom in eulipotyphlan mammals, Nicholas R. Casewell and Elinor K. Karlsson

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Preferences, use of and satisfaction with mental health services among a sample of Puerto Rican cancer patients, Eida M. Castro-Figueroa, Normarie Torres-Blasco, Milagros C. Rosal, Wallesca P. Castro, Marilis E. Gonzalez-Lorenzo, Hector Velez, Rosario Costas-Muniz, and Julio C. Jimenez

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Evaluation of prophylactic dosages of Enoxaparin in non-surgical elderly patients with renal impairment, Nibal Chamoun, Hady Ghanem, Ahmad Hachem, Essa Hariri, Christelle Lteif, Hanine Mansour, Hani Dimassi, Richard Zalloum, and Georges Ghanem

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Multi-Site Photoplethysmography Technology for Blood Pressure Assessment: Challenges and Recommendations, Gabriel Chan, Rachel Cooper, Manish Hosanee, Kaylie Welykholowa, Panayiotis A. Kyriacou, Dingchang Zheng, John Allen, Derek Abbott, Nigel H. Lovell, Richard Fletcher, and Mohamed Elgendi

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The immune checkpoint molecules PD-1, PD-L1, TIM-3 and LAG-3 in diffuse large B-cell lymphoma, Benjamin J. Chen, Ravi Dashnamoorthy, Pallavi Galera, Vladislav Makarenko, Hong Chang, Srimoyee Ghosh, and Andrew M. Evens

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Detecting Hypoglycemia Incidents Reported in Patients' Secure Messages: Using Cost-Sensitive Learning and Oversampling to Reduce Data Imbalance, Jinying Chen, John Lalor, Weisong Liu, Emily Druhl, Edgard A. Granillo, Varsha G. Vimalananda, and Hong Yu

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The Tec kinase ITK is essential for ILC2 survival and epithelial integrity in the intestine, Hyoung-Soo Cho, Andrea Reboldi, Jason A. Hall, and Leslie J. Berg

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The C. elegans heterochronic gene lin-28 coordinates the timing of hypodermal and somatic gonadal programs for hermaphrodite reproductive system morphogenesis, Sungwook Choi and Victor R. Ambros

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mHealth technologies for osteoarthritis self-management and treatment: A systematic review, Wonchan Choi, Hua Zheng, Patricia D. Franklin, and Bengisu Tulu

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Toll family members bind multiple Spatzle proteins and activate antimicrobial peptide gene expression in Drosophila, Munmun Chowdhury, Chun-Feng Li, Zhen He, Yuzhen Lu, Xu-Sheng Liu, Yu-Feng Wang, Y. Tony Ip, Michael R. Strand, and Xiao-Qiang Yu

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Role of Balloon Guide Catheter in Modern Endovascular Thrombectomy, Ju-Yu Chueh, Dong-Hun Kang, Byung Moon Kim, and Matthew J. Gounis

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Nonnative structure in a peptide model of the unfolded state of SOD1: Implications for ALS-linked aggregation, Noah R. Cohen, Jill A. Zitzewitz, Osman Bilsel, and C. Robert Matthews

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The relation between mental health problems and future violence among detained male juveniles, Olivier F. Colins and Thomas Grisso

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A Novel Tool to Improve Shared Decision Making and Adherence in Multiple Sclerosis: Development and Preliminary Testing, Nananda Col, Enrique Alvarez, Vicky Springmann, Carolina Ionete, Idanis Berrios Morales, Andrew Solomon, Christen Kutz, Carolyn Griffin, Brenda Tierman, Terrie Livingston, Michelle Patel, Danny van Leeuwen, Long Ngo, and Lori Pbert

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Mutations in the Glycosyltransferase Domain of GLT8D1 Are Associated with Familial Amyotrophic Lateral Sclerosis, Johnathan Cooper-Knock, John E. Landers, and Pamela J. Shaw

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JNK and cardiometabolic dysfunction, Siobhan M. Craige, Kai Chen, Robert M. Blanton, John F. Keaney Jr., and Shashi Kant

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Antimicrobial Resistance in Neisseria gonorrhoeae: Proceedings of the STAR Sexually Transmitted Infection-Clinical Trial Group Programmatic Meeting, Anthony D. Cristillo and Peter A. Rice

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BID-ding on necroptosis in MDS, Ben A. Croker and Michelle A. Kelliher

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Comparison of Immune Responses to Different Versions of VLP Associated Stabilized RSV Pre-Fusion F Protein, Lori M. Cullen, Madelyn R. Schmidt, Gretel M. Torres, Adam A. Capoferri, and Trudy G. Morrison

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Will savings from biosimilars offset increased costs related to dose escalation? A comparison of infliximab and golimumab for rheumatoid arthritis, Jeffrey R. Curtis, Fenglong Xie, Jonathan Kay, and Joel D. Kallich

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Harnessing robotic automation and web-based technologies to modernize scientific outreach, Orna Dahan, Bat-Shahar Dorfman, Serkan Sayin, Brittany Rosener, Tiffany Hua, Anat Yarden, and Amir Mitchell

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Control of cellular responses to mechanical cues through YAP/TAZ regulation, Ishani Dasgupta and Dannel McCollum

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Structural Organization and Dynamics of Homodimeric Cytohesin Family Arf GTPase Exchange Factors in Solution and on Membranes, Sanchaita Das, Andrew W. Malaby, Agata Nawrotek, Wenhua Zhang, Mahel Zeghouf, Sarah Maslen, Mark Skehel, Srinivas Chakravarthy, Thomas C. Irving, Osman Bilsel, Jacqueline Cherfils, and David G. Lambright

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Accelerated knee osteoarthritis is associated with pre-radiographic degeneration of the extensor mechanism and cruciate ligaments: data from the Osteoarthritis Initiative, Julie E. Davis, Matthew S. Harkey, Robert J. Ward, James W. MacKay, Bing Lu, Lori Lyn Price, Charles B. Eaton, Grace H. Lo, Mary F. Barbe, Timothy E. McAlindon, and Jeffrey B. Driban

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A Fifty-Two-Week, Randomized, Placebo-Controlled Trial of Certolizumab Pegol in Nonradiographic Axial Spondyloarthritis, Atul Deodhar, Lianne S. Gensler, Jonathan Kay, Walter P. Maksymowych, Nigil Haroon, Robert Landewe, Martin Rudwaleit, Stephen Hall, Lars Bauer, Bengt Hoepken, Natasha de Peyrecave, Brian Kilgallen, and Desiree van der Heijde

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Identification of the hyaluronic acid pathway as a therapeutic target for facioscapulohumeral muscular dystrophy, Alec M. DeSimone; John D. Leszyk; Kathryn Wagner; and Charles P. Emerson, Jr.

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Rapid Irreversible Transcriptional Reprogramming in Human Stem Cells Accompanied by Discordance between Replication Timing and Chromatin Compartment, Vishnu Dileep, Rachel Patton McCord, Job Dekker, and David M. Gilbert

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Accuracy and Usability of a Novel Algorithm for Detection of Irregular Pulse Using a Smartwatch Among Older Adults: Observational Study, Eric Y. Ding, Dong Han, Cody Whitcomb, Syed Khairul Bashar, Oluwaseun Adaramola, Apurv Soni, Jane Saczynski, Timothy P. Fitzgibbons, Majaz Moonis, Steven A. Lubitz, Darleen M. Lessard, Mellanie True Hills, Bruce A. Barton, Ki Chon, and David D. McManus

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High-fat diet in a mouse insulin-resistant model induces widespread rewiring of the phosphotyrosine signaling network, Antje Dittmann, Norman J. Kennedy, Nina L. Soltero, Nader Morshed, Miyeko D. Mana, Omer H. Yilmaz, Roger J. Davis, and Forest M. White

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Correction of pseudoexon splicing caused by a novel intronic dysferlin mutation, Janice A. Dominov, Ozgun Uyan, Diane McKenna-Yasek, Babi Ramesh Reddy Nallamilli, Virginie Kergourlay, Marc Bartoli, Nicolas Levy, Judith Hudson, Teresinha Evangelista, Hanns Lochmuller, Martin Krahn, Laura Rufibach, Madhuri Hegde, and Robert H. Brown Jr.

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Elbow Ulnar Collateral Ligament Reconstruction Using the Novel Docking Plus Technique in 324 Athletes, Benjamin F. Donohue, Marc G. Lubitz, and Timothy E. Kremchek