Open Access is free, unrestricted, online access to scientific and scholarly research. This collection includes Open Access journal articles and other materials authored by researchers, faculty, staff, and students at UMass Chan Medical School.

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Publications from 2018

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Myeloablative vs reduced-intensity conditioning allogeneic hematopoietic cell transplantation for chronic myeloid leukemia, Saurabh Chhabra and Jan Cerny

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Trisomy silencing by XIST normalizes Down syndrome cell pathogenesis demonstrated for hematopoietic defects in vitro, Jen-Chieh Chiang, Jun Jiang, Peter E. Newburger, and Jeanne B. Lawrence

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Association of arginine vasopressin with low atrial natriuretic peptide levels, left ventricular remodelling, and outcomes in adults with and without heart failure, Julio A. Chirinos, Mayank Sardana, Garrett Oldland, Bilal Ansari, Jonathan Lee, Anila Hussain, Anique Mustafa, Scott R. Akers, Wen Wei, Edward G. Lakatta, and Olga V. Fedorova

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Quantitative Profiling of the Lymph Node Clearance Capacity, Cristina C. Clement, Wei Wang, Monika Dzieciatkowska, Marco Cortese, Kirk C. Hansen, Aniuska Becerra, Sangeetha Thangaswamy, Irina Nizamutdinova, Jee-Young Moon, Lawrence J. Stern, Anatoliy A. Gashev, David Zawieja, and Laura Santambrogio

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Immunocontraceptive target repertoire defined by systematic identification of sperm membrane alloantigens in a single species, Nathaly Cormier, John J. McGlone, John D. Leszyk, and Daniel M. Hardy

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VIPER: Visualization Pipeline for RNA-seq, a Snakemake workflow for efficient and complete RNA-seq analysis, MacIntosh Cornwell, Mahesh Vangala, Len Taing, Zachary Herbert, Johannes Koster, Bo Li, Hanfei Sun, Taiwen Li, Jian Zhang, Xintao Qiu, Matthew Pun, Rinath Jeselsohn, Myles Brown, X Shirley Liu, and Henry W. Long

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A Long Cytoplasmic Loop Governs the Sensitivity of the Anti-viral Host Protein SERINC5 to HIV-1 Nef, Weiwei Dai, Yoshiko Usami, Yuanfei Wu, and Heinrich G. Gottlinger

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Plasma Circulating Extracellular RNAs in Left Ventricular Remodeling Post-Myocardial Infarction, Kirsty M. Danielson, Kahraman Tanriverdi, Jane E. Freedman, and Saumya Das

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Evaluation of a Multimodal, Direct-to-Patient Educational Intervention Targeting Barriers to Osteoporosis Care: A Randomized Clinical Trial, Maria I. Danila, Jeroan J. Allison, Frederick A. Anderson Jr., Allison Wyman, and Kenneth G. Saag

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The TRIM-NHL protein NHL-2 is a co-factor in the nuclear and somatic RNAi pathways in C. elegans, Gregory M. Davis, Shikui Tu, Jacqueline A. Wilce, Julie M. Claycomb, Zhiping Weng, and Peter R. Boag

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Deciphering the molecular basis of mycobacteria and lipoglycan recognition by the C-type lectin Dectin-2, Alexiane Decout, Devinder Kaur, and Jerome Nigou

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ALS-associated missense and nonsense TBK1 mutations can both cause loss of kinase function, Martina de Majo, Kevin P. Kenna, Robert H. Brown Jr., John E. Landers, and Christopher E. Shaw

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Interleukin-1 receptor-associated kinase 4 (IRAK4) plays a dual role in myddosome formation and Toll-like receptor signaling, Dominic De Nardo, Katherine R. Balka, Yamel Cardona Gloria, Vikram R. Rao, Eicke Latz, and Seth L. Masters

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Pathogen Recognition by CD4 Effectors Drives Key Effector and Most Memory Cell Generation Against Respiratory Virus, Priyadharshini Devarajan, Michael C. Jones, Olivia Kugler-Umana, Allen M. Vong, Jingya Xia, and Susan L. Swain

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Histone citrullination represses miRNA expression resulting in increased oncogene mRNAs in somatolactotrope cells., Stanley B DeVore, Coleman H. Young, Guangyuan Li, Anitha Sundararajan, Thiruvarangan Ramaraj, Joann Mudge, Faye Schilkey, Aaron Muth, Paul R. Thompson, and Brian D. Cherrington

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Total body CD4+ T cell dynamics in treated and untreated SIV infection revealed by in vivo imaging, Michele Di Mascio, Sharat Srinivasula, Insook Kim, Gorka Duralde, Alexis St. Claire, Paula DeGrange, Marisa St. Claire, Keith A. Reimann, Erin E. Gabriel, Jorge Carrasquillo, Richard C. Reba, Chang Paik, and Henry C. Lane

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Stress-responsive and metabolic gene regulation are altered in low S-adenosylmethionine, Wei Ding, Daniel P. Higgins, Dilip K. Yadav, Adwait A. Godbole, Read Pukkila-Worley, and Amy K. Walker

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The principles and practice of open fracture care, 2018, Amna Diwan, Kyle R. Eberlin, and Raymond Malcolm Smith

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Robust Genome Editing with Short Single-Stranded and Long, Partially Single-Stranded DNA Donors in Caenorhabditis elegans, Gregoriy A. Dokshin, Krishna S. Ghanta, Katherine M. Piscopo, and Craig C. Mello

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Association Between Sarcopenia and Functional Status in Liver Transplant Patients, Natasha H. Dolgin, Andrew J. Smith, Samantha G. Harrington, Babak Movahedi, Paulo N.A. Martins, and Adel Bozorgzadeh

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Methods for high-dimensonal analysis of cells dissociated from cyropreserved synovial tissue, Laura T. Donlin, Ellen M. Gravallese, and Jennifer H. Anolik

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Upregulation of HLA-E by dengue and not Zika viruses, Elena Drews, Awadalkareem Adam, Phone Htoo, Elizabeth Townsley, and Anuja Mathew

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Complete and Durable Responses in Primary Central Nervous System Posttransplant Lymphoproliferative Disorder with Zidovudine, Ganciclovir, Rituximab, and Dexamethasone, James P. Dugan, Joyce D. Fingeroth, and Robert A. Baiocchi

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ETV4 transcription factor and MMP13 metalloprotease are interplaying actors of breast tumorigenesis, Mandy Dumortier, Franck Ladam, Isabelle Damour, Sophie Vacher, Ivan Bieche, Nathalie Marchand, Yvan de Launoit, David Tulasne, and Anne Chotteau-Lelievre

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Using virtual reality in medical education to teach empathy, Elizabeth Dyer, Barbara J. Swartzlander, and Marilyn R. Gugliucci

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Genetic Models Reveal cis and trans Immune-Regulatory Activities for lincRNA-Cox2, Roland Elling, Zhaozhao Jiang, Shiuli Agarwal, Mona Motwani, Jennie Chan, Shrutie Sharma, Katherine A. Fitzgerald, and Susan Carpenter

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Pre-diagnosis plasma immune markers and risk of non-Hodgkin lymphoma in two prospective cohort studies, Mara M. Epstein, Bernard Rosner, Elizabeth C. Breen, Julie L. Batista, Edward L. Giovannucci, Larry Magpantay, Jon C. Aster, Scott J. Rodig, Kimberly A. Bertrand, Francine Laden, Otoniel Martinez-Maza, and Brenda M. Birmann

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The wide utility of rabbits as models of human diseases, Pedro J. Esteves, Yuxing Chen, Shuying Liu, Shan Lu, Michael Vaine, Shixia Wang, and Rose Mage

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Antiplatelet Therapy Changes for Patients With Myocardial Infarction With Recurrent Ischemic Events: Insights Into Contemporary Practice From the TRANSLATE-ACS (Treatment With ADP Receptor Inhibitors: Longitudinal Assessment of Treatment Patterns and Events After Acute Coronary Syndrome) Study, Alexander C. Fanaroff, Lisa A. Kaltenbach, Eric D. Peterson, Mohammed W. Akhter, Mark B. Effron, Timothy D. Henry, and Tracy Y. Wang

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Explantation of infected thoracic endovascular aortic repair, Emily Y. Fan, Dejah R. Judelson, and Andres Schanzer

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Comparing efficacy of lumen-apposing stents to plastic stents in the endoscopic management of mature peripancreatic fluid collections: a single-center experience, Matthew J. Fasullo, Yasir Al-Azzawai, Joan Kheder, Jeffrey Abergel, and Wahid Y. Wassef

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Hodgkin Lymphoma: Differences in Treatment Between Europe and the United States/North America: Evolving Trends in Protocol Therapy, Thomas J. Fitzgerald and Maryann Bishop-Jodoin

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Relationship Between Theory of Mind, Emotion Recognition, and Social Synchrony in Adolescents With and Without Autism, Paula Fitzpatrick, Jean A. Frazier, David E. Cochran, Teresa V. Mitchell, Caitlin Coleman, and R. C. Schmidt

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Transient transcriptional silencing alters the cell cycle to promote germline stem cell differentiation in Drosophila, Pooja Flora, Sean Schowalter, SiuWah Wong-Deyrup, Matthew DeGennaro, Mohamad Ali Nasrallah, and Prashanth Rangan

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Poorly cytotoxic terminally differentiated CD56(neg)CD16(pos) NK cells accumulate in Kenyan children with Burkitt lymphomas, Catherine Forconi, Cormac P. Cosgrove, Pryia Saikumar-Lakshmi, Christina E. Nixon, Joslyn Foley, John Michael Ong'echa, Juliana A. Otieno, Galit Alter, Christian Munz, and Ann M. Moormann

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Protective versus pathologic pre-exposure cytokine profiles in dengue virus infection, Heather Friberg, Coreen M. Beaumier, Sangshin Park, Pamela P. Pazoles, Timothy P. Endy, Anuja Mathew, Jeffrey R. Currier, Richard G. Jarman, Kathryn B. Anderson, Steven Hatch, Stephen J. Thomas, and Alan L. Rothman

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Metastatic Extramammary Paget's Disease: Pathogenesis and Novel Therapeutic Approach, Keitaro Fukuda and Takeru Funakoshi

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Rare gene fusion rearrangement SPTNB1-PDGFRB in an atypical myeloproliferative neoplasm, Vanessa Fiorini Furtado, Neeraj Y. Saini, William V. Walsh, Venu G. Bathini, and Patricia M. Miron

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Differential analysis of chromatin accessibility and histone modifications for predicting mouse developmental enhancers, Shaliu Fu, Qin Wang, Jill E. Moore, Michael J. Purcaro, Henry E. Pratt, Kaili Fan, Cuihua Gu, Cizhong Jiang, Ruixin Zhu, Anshul Kundaje, Aiping Lu, and Zhiping Weng

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Elimination of PCR duplicates in RNA-seq and small RNA-seq using unique molecular identifiers, Yu Fu, Pei-Hsuan Wu, Timothy J. Beane, Phillip D. Zamore, and Zhiping Weng

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The genome of the Hi5 germ cell line from Trichoplusia ni, an agricultural pest and novel model for small RNA biology, Yu Fu, Yujing Yang, Han Zhang, Gwen Farley, Junling Wang, Kaycee A. Quarles, Zhiping Weng, and Phillip D. Zamore

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One Group's Historical Reflections on DNA Vaccine Development, Ellen F. Fynan, Shan Lu, and Harriet L. Robinson

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Congenital Heart Defects and Ciliopathies Associated With Renal Phenotypes, George C. Gabriel, Gregory J. Pazour, and Cecilia W. Lo

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Peptide Antigen Concentration Modulates Digital NFAT1 Activation in Primary Mouse Naive CD8(+) T Cells as Measured by Flow Cytometry of Isolated Cell Nuclei, Michael P. Gallagher, James M. Conley, and Leslie J. Berg

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Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018, Lorenzo Galluzzi, Eric H. Baehrecke, Francis Ka-Ming Chan, and Guido Kroemer

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Excitatory motor neurons are local oscillators for backward locomotion, Shangbang Gao, Sihui Asuka Guan, Anthony D. Fouad, Jun Meng, Taizo Kawano, Yung-Chi Huang, Yi Li, Salvador Alcaire, Wesley Hung, Yangning Lu, Yingchuan Billy Qi, Yishi Jin, Mark J. Alkema, Christopher Fang-Yen, and Mei Zhen

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The AGING Initiative experience: a call for sustained support for team science networks, Tullika Garg, Kathryn Anzuoni, Valentina Landyn, Alexandra Hajduk, Stephen Waring, Leah R. Hanson, and Heather E. Whitson

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Analysis of novel caudal hindbrain genes reveals different regulatory logic for gene expression in rhombomere 4 versus 5/6 in embryonic zebrafish, Priyanjali Ghosh, Jennifer M. Maurer, and Charles G. Sagerstrom

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The cJUN NH2-terminal kinase (JNK) signaling pathway promotes genome stability and prevents tumor initiation, Nomeda A. Girnius, Yvonne J. K. Edwards, David S. Garlick, and Roger J. Davis

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Identification and Characterization of Human Monoclonal Antibodies for Immunoprophylaxis Against Enterotoxigenic Escherichia coli Infection, Serena Giuntini, Matteo Stoppato, Maja Sedic, Ejemel Monir, Jessica R. Pondish, Danielle Wisheart, Zachary Schiller, William D. Thomas Jr., Eileen M. Barry, Lisa Cavacini, mark S. klempner, and Yan Wang

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Therapeutic benefit of apremilast on enthesitis and dactylitis in patients with psoriatic arthritis: a pooled analysis of the PALACE 1-3 studies, Dafna D. Gladman, Arthur Kavanaugh, Juan J. Gomez-Reino, Jurgen Wollenhaupt, Maurizio Cutolo, Georg Schett, Eric Lespessailles, Benoit Guerette, Nikolay Delev, Lichen Teng, Christopher J. Edwards, Charles Birbara, and Philip J. Mease

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Supporting Family Physician Maternity Care Providers, Jessica Taylor Goldstein, Scott G. Hartman, Matthew R. Meunier, Bethany Panchal, Christine Chang Pecci, Nancy M. Zink, and Sara G. Shields

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Optical Temperature Sensing With Infrared Excited Upconversion Nanoparticles, Kory Green, Kai Huang, Hai Pan, Gang Han, and Shuang Fang Lim

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Device Therapies Among Patients Receiving Primary Prevention Implantable Cardioverter-Defibrillators in the Cardiovascular Research Network, Robert T. Greenlee, Jerry H. Gurwitz, and David D. McManus

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Breathing New Life into Interstitial Lung Disease in Rheumatoid Arthritis, Peter K. Gregersen and Ellen M. Gravallese

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Harmonization of delirium severity instruments: a comparison of the DRS-R-98, MDAS, and CAM-S using item response theory, Alden L. Gross, Doug Tommet, Madeline D'Aquila, Eva Schmitt, Edward R. Marcantonio, Benjamin Helfand, Sharon K. Inouye, and Richard N. Jones

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Patterns of civilian and child deaths due to war-related violence in Syria: a comparative analysis from the Violation Documentation Center dataset, 2011-16, Debarati Guha-Sapir, Benjamin Schluter, Jose Manuel Rodriguez-Llanes, Louis Lillywhite, and Madelyn J. Hsiao-Rei Hicks

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Neuronal modulation of brown adipose activity through perturbation of white adipocyte lipogenesis, Adilson L. Guilherme, David J. Pedersen, Felipe Henriques, Alexander H. Bedard, Elizabeth Henchey, Mark Kelly, Donald A. Morgan, Kamal Rahmouni, and Michael P. Czech

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A large-scale RNA interference screen identifies genes that regulate autophagy at different stages, Sujuan Guo, Kevin J. Pridham, Ching-Man A. Virbasius, Bin He, Liqing Zhang, Hanne Varmark, Michael R. Green, and Zhi Sheng

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Research evaluation support services in biomedical libraries, Karen Elizabeth Gutzman, Michael E. Bales, Christopher W. Belter, Thane Chambers, Liza Chan, Kristi L. Holmes, Ya-Ling Lu, Lisa A. Palmer, Rebecca Reznik-Zellen, Cathy C. Sarli, Amy M. Suiter, and Terrie R. Wheeler

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Determining the scope of attacks on health in four governorates of Syria in 2016: Results of a field surveillance program, Rohini J. Haar, Casey B. Risko, Sonal Singh, Diana Rayes, Ahmad Albaik, Mohammed Alnajar, Mazen Kewara, Emily Clouse, Elise Baker, and Leonard S. Rubenstein

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Video capsule endoscopy as a tool for evaluation of obscure overt gastrointestinal bleeding in the intensive care unit, Shahrad Hakimian, Salmaan Jawaid, Yurima Guilarte-Walker, Jomol Mathew, and David R. Cave

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The conundrum of indeterminate QuantiFERON-TB Gold results before anti-tumor necrosis factor initiation, Shahrad Hakimian, Yevgeniy Popov, Abbas Rupawala, Karen I. Salomon-Escoto, Steven Hatch, and Randall Pellish

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The impact of deliberate reflection with WISE-MD modules on surgical clerkship students' critical thinking: a prospective, randomized controlled pilot study, Janet Fraser Hale, Jill M. Terrien, Mark E. Quirk, Kate Sullivan, and Mitchell A. Cahan

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Suspected Blood Indicator to Identify Active Gastrointestinal Bleeding: A Prospective Validation, Samuel Han, Julien Fahed, and David R. Cave

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Nitro-fatty acids are formed in response to virus infection and are potent inhibitors of STING palmitoylation and signaling, Anne Louise Hansen, Mona Motwani, Katherine A. Fitzgerald, and Christian K. Holm

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Exosomes Produced from 3D Cultures of MSCs by Tangential Flow Filtration Show Higher Yield and Improved Activity, Reka A. Haraszti, Rachael Miller, Matteo Stoppato, Yves Y. Sere, Andrew H. Coles, Marie-Claire Daou, Rachel Wollacott, Ellen Sapp, Michelle L. Dubuke, Xuni Li, Scott A. Shaffer, Marian DiFiglia, Yan Wang, Neil Aronin, and Anastasia Khvorova

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Effect of Anticitrullinated Protein Antibody Status on Response to Abatacept or Antitumor Necrosis Factor-alpha Therapy in Patients with Rheumatoid Arthritis: A US National Observational Study, Leslie R. Harrold, Heather J. Litman, Sean E. Connolly, Sheila Kelly, Winnie Hua, Evo Alemao, Lisa Rosenblatt, Sabrina Rebello, and Joel M. Kremer

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One-year risk of serious infection in patients treated with certolizumab pegol as compared with other TNF inhibitors in a real-world setting: data from a national U.S. rheumatoid arthritis registry, Leslie R. Harrold, Heather J. Litman, Katherine C. Saunders, Kimberly J. Dandreo, Bernice Gershenson, Jeffrey D. Greenberg, Robert Low, Jeffrey Stark, Robert Suruki, Srihari Jaganathan, Joel M. Kremer, and Mohamed Yassine

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Real-world Comparative Effectiveness of Tocilizumab Monotherapy vs. Tumor Necrosis Factor Inhibitors with Methotrexate in Patients with Rheumatoid Arthritis, Leslie R. Harrold, George W. Reed, Jennie Best, Steve Zlotnick, and Joel M. Kremer

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Cluster-Randomized Trial of a Behavioral Intervention to Incorporate a Treat-to-Target Approach to Care of US Patients With Rheumatoid Arthritis, Leslie R. Harrold, George W. Reed, Ani John, Christine J. Barr, Kevin Soe, Robert P. Magner, Katherine C. Saunders, Eric M. Ruderman, Tmirah Haselkorn, Jeffrey D. Greenberg, Allan Gibofsky, J. Timothy Harrington, and Joel M. Kremer

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Cystic fibrosis-related diabetes is caused by islet loss and inflammation, Nathaniel J. Hart, Jenny Aurielle B. Babon, Megan E. DeNicola, Sally C. Kent, and Alvin C. Powers

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Polymorphic factor H-binding activity of CspA protects Lyme borreliae from the host complement in feeding ticks to facilitate tick-to-host transmission, Thomas Hart, Ngoc Thien Nguyen Thu, Nancy A. Nowak, Fuming Zhang, Robert J. Linhardt, Maria Diuk-Wasser, Sanjay Ram, Peter Kraiczy, and Yi-Pin Lin

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Comparison of partially and fully chemically-modified siRNA in conjugate-mediated delivery in vivo, Matthew R. Hassler, Anton A. Turanov, Julia F. Alterman, Reka A. Haraszti, Andrew H. Coles, Maire F. Osborn, Dimas Echeverria, Mehran Nikan, William E. Salomon, Loic Roux, Bruno M. D. C. Godinho, Sarah M. Davis, David V. Morrissey, Phillip D. Zamore, S. Ananth Karumanchi, Melissa J. Moore, Neil Aronin, and Anastasia Khvorova

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SeekDeep: single-base resolution de novo clustering for amplicon deep sequencing, Nicholas J. Hathaway, Christian M. Parobek, Jonathan J. Juliano, and Jeffrey A. Bailey

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Identification of a novel anoikis signalling pathway using the fungal virulence factor gliotoxin, Florian Haun, Simon Neumann, Lukas Peintner, Katrin Wieland, Juri Habicht, Carsten Schwan, Kristine Ostevold, Maria Magdalena Koczorowska, Martin Biniossek, Matthias Kist, Hauke Busch, Melanie Boerries, Roger J. Davis, Ulrich Maurer, Oliver Schilling, Klaus Aktories, and Christoph Borner

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General decapping activators target different subsets of inefficiently translated mRNAs, Feng He, Alper Celik, Chan Wu, and Allan Jacobson

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Successful Renal Transplantation after Presumed Cyanide Toxicity Treated with Hydroxocobalamin and Review of the Literature, Ryan J. Hendrix, Paulo N.A. Martins, Jeffrey S. Stoff, Aaron Ahearn, Adel Bozorgzadeh, and Babak Movahedi

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Toll-Like Receptor-4 Disruption Suppresses Adipose Tissue Remodeling and Increases Survival in Cancer Cachexia Syndrome, Felipe Henriques, Magno A. Lopes, Felipe O. Franco, Pamela Knobl, Kaltinaitis B. Santos, Luana L. Bueno, Victor A. Correa, Alexander H. Bedard, Adilson L. Guilherme, Alexander Birbrair, Sidney B. Peres, Stephen R. Farmer, and Miguel L. Batista Jr.

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Down-regulation of microRNA-203-3p initiates type 2 pathology during schistosome infection via elevation of interleukin-33, Xing He, Jun Xie, Yange Wang, Xiaobin Fan, Qin Su, Yue Sun, Nanhang Lei, Dongmei Zhang, Guangping Gao, and Weiqing Pan

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Identification of Epigenetic Regulators of DUX4-fl for Targeted Therapy of Facioscapulohumeral Muscular Dystrophy, Charis L. Himeda, Takako I. Jones, Ching-Man A. Virbasius, Lihua Julie Zhu, Michael R. Green, and Peter L. Jones

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A Case of Granulocytic Sarcoma or Extramedullary Acute Myelomonocytic Leukemia of the Gallbladder, Erik Holzwanger, Zainab Alam, Emily Hsu, Andrew Hsu, Mark Mangano, and Deirdre L. Kathman

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Autologous/Allogeneic Hematopoietic Cell Transplantation versus Tandem Autologous Transplantation for Multiple Myeloma: Comparison of Long-Term Postrelapse Survival, Myo Htut, Muthalagu Ramanathan, and Parameswaran Hari

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Inhibition of protein arginine methyltransferase 5 enhances hepatic mitochondrial biogenesis, Lei Huang, Jehnan Liu, Xiao-Ou Zhang, Katelyn Sibley, Sonia M. Najjar, Mary M. Lee, and Joae Qiong Wu

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Dynamic placement of the linker histone H1 associated with nucleosome arrangement and gene transcription in early Drosophila embryonic development, Jian Hu, Liang Gu, Youqiong Ye, Meizhu Zheng, Zhu Xu, Jing Lin, Yanhua Du, Mengxue Tian, Lifang Luo, Beibei Wang, Xiaobai Zhang, Zhiping Weng, and Cizhong Jiang

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The Caenorhabditis elegans Oxidative Stress Response Requires the NHR-49 Transcription Factor, Queenie Hu, Dayana R. D'Amora, Lesley T. MacNeil, Albertha J. M. Walhout, and Terrance J. Kubiseski

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In vivo and in vitro studies of Cry5B and nicotinic acetylcholine receptor agonist anthelmintics reveal a powerful and unique combination therapy against intestinal nematode parasites, Yan Hu, Melanie Miller, Bo Zhang, Thanh-thanh Nguyen, Martin K. Nielsen, and Raffi V. Aroian

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Bacillus thuringiensis Cry5B protein as a new pan-hookworm cure, Yan Hu, Thanh-thanh Nguyen, Alice C. Lee Y, Joseph F. Urban Jr, Melanie M. Miller, Bin Zhan, David Koch, Jason B. Noon, Ricardo Toshio. Fujiwara, Dwight D. Bowman, Gary R. Ostroff, and Raffi V. Aroian

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All-in-one adeno-associated virus delivery and genome editing by Neisseria meningitidis Cas9 in vivo, Raed Ibraheim, Chun-Qing Song, Aamir Mir, Nadia Amrani, Wen Xue, and Erik J. Sontheimer

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Biochemical Analysis of Dimethyl Suberimidate-crosslinked Yeast Nucleosomes, Yuichi Ichikawa and Paul D. Kaufman

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An asymmetric centromeric nucleosome, Yuichi Ichikawa, Noriko Saitoh, and Paul D. Kaufman

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Computer design of microfluidic mixers for protein/RNA folding studies, Venkatesh Inguva, Sagar V. Kathuria, Osman Bilsel, and Blair James Perot

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Maximum blink interval is associated with tear film breakup time: A new simple, screening test for dry eye disease, Takenori Inomata, Masao Iwagami, Yoshimune Hiratsuka, Keiichi Fujimoto, Yuichi Okumura, Tina Shiang, and Akira Murakami

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The impact of Joint Commission International accreditation on time periods in the operating room: A retrospective observational study, Takenori Inomata, Ju Mizuno, Masao Iwagami, Shiori Kawasaki, Akie Shimada, Eiichi Inada, Tina Shiang, and Atsushi Amano

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FXR and TGR5 Agonists Ameliorate Liver Injury, Steatosis, and Inflammation After Binge or Prolonged Alcohol Feeding in Mice, Arvin Iracheta-Vellve, Charles D. Calenda, Jan Petrasek, Aditya Ambade, Karen Kodys, Luciano Adorini, and Gyongyi Szabo

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Breastfeeding History and Risk of Stroke Among Parous Postmenopausal Women in the Women's Health Initiative, Lisette T. Jacobson, Erinn M. Hade, Tracie C. Collins, Karen L. Margolis, Molly E. Waring, Linda V. Van Horn, Brian Silver, Maryam Sattari, Chloe E. Bird, Kim Kimminau, Karen Wambach, and Marcia L. Stefanick

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Robust multivariate nonparametric tests for detection of two-sample location shift in clinical trials, Xuejun Jiang, Xu Guo, Ning Zhang, Bo Wang, and Bo Zhang

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Protocol for the ROSE sustainment (ROSES) study, a sequential multiple assignment randomized trial to determine the minimum necessary intervention to maintain a postpartum depression prevention program in prenatal clinics serving low-income women, Jennifer E. Johnson, Shannon Wiltsey-Stirman, Alla Sikorskii, Ted Miller, Amanda King, Jennifer L. Blume, Xuan Pham, Tiffany A. Moore Simas, Ellen Poleshuck, Rebecca Weinberg, and Caron Zlotnick

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A cre-inducible DUX4 transgenic mouse model for investigating facioscapulohumeral muscular dystrophy, Takako I. Jones and Peter L. Jones

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Towards an arthritis flare-responsive drug delivery system, Nitin Joshi, Ellen M. Gravallese, Joerg Ermann, and Jeffrey M. Karp