Open Access is free, unrestricted, online access to scientific and scholarly research. This collection includes Open Access journal articles authored by researchers, faculty, staff, and students of the University of Massachusetts Medical School.

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Publications from 2017

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Tolerability and Effectiveness of Exenatide Once Weekly Relative to Basal Insulin Among Type 2 Diabetes Patients of Different Races in Routine Care, Anthony P. Nunes, Anita M. Loughlin, Qing Qiao, Stephen M. Ezzy, Laura Yochum, C Robin. Clifford, Robert V. Gately, David D. Dore, and John D. Seeger

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Vitamin D status in pediatric irritable bowel syndrome, Benjamin U. Nwosu, Louise Maranda, and Ninfa Candela

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Coxsackievirus-Induced Proteomic Alterations in Primary Human Islets Provide Insights for the Etiology of Diabetes, Julius O. Nyalwidhe, Glen R. Gallagher, Lindsey M. Glenn, Margaret A. Morris, Pranitha Vangala, Agata Jurczyk, Rita Bortell, David M. Harlan, Jennifer P. Wang, and Jerry L. Nadler

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Integrative microRNA and mRNA deep-sequencing expression profiling in endemic Burkitt lymphoma, Cliff I. Oduor, Yasin Kaymaz, Kiprotich Chelimo, Juliana A. Otieno, John Michael Ong'echa, Ann M. Moormann, and Jeffrey A. Bailey

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Human and Epstein-Barr Virus miRNA Profiling as Predictive Biomarkers for Endemic Burkitt Lymphoma, Cliff I. Oduor, Mercedeh Movassagh, Yasin Kaymaz, Kiprotich Chelimo, Juliana A. Otieno, John M. Ong'echa, Ann M. Moormann, and Jeffrey A. Bailey

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Drosophila Model of Leishmania amazonensis Infection, Kendi Okuda and Neal S. Silverman

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The Combined Effect of Oseltamivir and Favipiravir on Influenza A Virus Evolution, Louise Ormond, Ping Liu, Sebastian Matuszewski, Nicholas Renzette, Claudia Bank, Konstantin B. Zeldovich, Daniel N. Bolon, Timothy F. Kowalik, Robert W. Finberg, Jeffrey D. Jensen, and Jennifer P. Wang

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RNA sequencing and proteomics approaches reveal novel deficits in the cortex of Mecp2-deficient mice, a model for Rett syndrome, Natasha L. Pacheco, Michael R. Heaven, Leanne M. Holt, David K. Crossman, Kristin J. Boggio, Scott A. Shaffer, Daniel L. Flint, and Michelle L. Olsen

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Decreased Functional Connectivity of Insular Cortex in Drug Naive First Episode Schizophrenia: In Relation to Symptom Severity, Lijuan Pang, David N. Kennedy, Qinling Wei, Luxian Lv, Jinsong Gao, Hong Li, Meina Quan, Xue Li, Yongfeng Yang, Xiaoduo Fan, and Xueqin Song

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Long-Term Effectiveness of Adalimumab in Patients with Rheumatoid Arthritis: An Observational Analysis from the Corrona Rheumatoid Arthritis Registry, Dimitrios A. Pappas, Joel M. Kremer, Jenny Griffith, George W. Reed, Bob Salim, Chitra Karki, and Vishvas Garg

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DISC1 Modulates Neuronal Stress Responses by Gate-Keeping ER-Mitochondria Ca(2+) Transfer through the MAM, Sung Jin Park, Su Been Lee, Yeongjun Suh, Su-Jeong Kim, Namgyu Lee, Ji-Ho Hong, Cana Park, Youngsik Woo, Koko Ishizuka, Joung-Hun Kim, Per-Olof Berggren, Akira Sawa, and Sang Ki Park

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Partner-Drug Resistance and Population Substructuring of Artemisinin-Resistant Plasmodium falciparum in Cambodia, Christian M. Parobek, Jonathan B. Parr, Nicholas F. Brazeau, Chanthap Lon, Suwanna Chaorattanakawee, Panita Gosi, Eric J. Barnett, Lauren D. Norris, Steven R. Meshnick, Michele D. Spring, Charlotte A. Lanteri, Jeffrey A. Bailey, David L. Saunders, Jessica T. Lin, and Jonathan J. Juliano

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Loss of Arf4 causes severe degeneration of the exocrine pancreas but not cystic kidney disease or retinal degeneration, Jillian N. Pearring, Jovenal T. San Agustin, Ekaterina S. Lobanova, Christopher J. Gabriel, Eric C. Lieu, William J. Monis, Michael W. Stuck, Lara Strittmatter, Samer M. Jaber, Vadim Y. Arshavsky, and Gregory J. Pazour

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Arteriovenous fistula patency in the 3 years following vonapanitase and placebo treatment, Eric K. Peden, Timothy P. O'Connor, Barry J. Browne, Bradley S. Dixon, Andres Schanzer, Stephen C. Jensik, Albert D. Sam 2nd, and Steven K. Burke

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Locked Nucleic Acid Gapmers and Conjugates Potently Silence ADAM33, an Asthma-Associated Metalloprotease with Nuclear-Localized mRNA, Hannah M. Pendergraff, Pranathi Meda Krishnamurthy, Alexandre J. Debacker, Michael P. Moazami, Vivek K. Sharma, Liisa Niitsoo, Yong Yu, Yen Nee Tan, Hans Michael Haitchi, and Jonathan K. Watts

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Novel Epstein-Barr virus-like particles incorporating gH/gL-EBNA1 or gB-LMP2 induce high neutralizing antibody titers and EBV-specific T-cell responses in immunized mice, Elizabeth M. Perez, Joslyn Foley, Timelia Tison, Rute Silva, and Javier Gordon Ogembo

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Tumor-promoting function of apoptotic caspases by an amplification loop involving ROS, macrophages and JNK in Drosophila, Ernesto Perez, Jillian L. Lindblad, and Andreas Bergmann

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Comparison of Inappropriate Shocks and Other Health Outcomes Between Single- and Dual-Chamber Implantable Cardioverter-Defibrillators for Primary Prevention of Sudden Cardiac Death: Results From the Cardiovascular Research Network Longitudinal Study of Implantable Cardioverter-Defibrillators, Pamela N. Peterson and Jerry H. Gurwitz

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Clinicopathologic consensus study of gray zone lymphoma with features intermediate between DLBCL and classical HL, Monika Pilichowska, Bruce A. Woda, Elaine S. Jaffe, and Andrew M. Evens

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High-Grade Partial and Retracted (less than 2 cm) Proximal Hamstring Ruptures: Nonsurgical Treatment Revisited, Jonathan R. Piposar, Amrit V. Vinod, Joshua R. Olsen, Edward Lacerte, and Suzanne L. Miller

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A general neurologist's perspective on the urgent need to apply resilience thinking to the prevention and treatment of Alzheimer's disease, Grazyna Pomorska and Judith K. Ockene

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5C analysis of the Epidermal Differentiation Complex locus reveals distinct chromatin interaction networks between gene-rich and gene-poor TADs in skin epithelial cells, Krzysztof Poterlowicz, Joanne L. Yarker, Igor Malashchuk, Brian R. Lajoie, Andrei N. Mardaryev, Michal R. Gdula, Andrey A. Sharov, Terumi Kohwi-Shigematsu, Vladimir A. Botchkarev, and Michael Y. Fessing

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Systems Immunology of Diabetes-Tuberculosis Comorbidity Reveals Signatures of Disease Complications, Cesar A. Prada-Medina, Kiyoshi F. Fukutani, Nathella Pavan Kumar, Leonardo Gil-Santana, Subash Babu, Flavio Lichtenstein, Kim West, Shanmugam Sivakumar, Pradeep A. Menon, Vijay Viswanathan, Bruno B. Andrade, Helder I. Nakaya, and Hardy Kornfeld

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Hereditary Renal Amyloidosis Associated With a Novel Apolipoprotein A-II Variant, Tatiana Prokaeva, Harun Akar, Brian Spencer, Andrea Havasi, Haili Cui, Carl J. O'Hara, Olga Gursky, John D. Leszyk, Martin Steffen, Sabrina Browning, Allison Rosenberg, and Lawreen H. Connors

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Missing the target: including perspectives of women with overweight and obesity to inform stigma-reduction strategies, Rebecca M. Puhl, M. S. Himmelstein, A. A. Gorin, and Young J. Suh

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MicroRNAs of the mir-17~92 cluster regulate multiple aspects of pancreatic tumor development and progression, Brian J. Quattrochi, Anushree Gulvady, David R. Driscoll, Makoto Sano, David S. Klimstra, Christopher E. Turner, and Brian C. Lewis

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Robust Identification of Developmentally Active Endothelial Enhancers in Zebrafish Using FANS-Assisted ATAC-Seq, Aurelie Quillien, Mary Abdalla, Jun Yu, Jianhong Ou, Lihua (Julie) Zhu, and Nathan D. Lawson

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Validity of the Nurses' health study physical activity questionnaire in estimating physical activity in adults with rheumatoid arthritis, Thomas Quinn, Michelle Frits, Johan von Heideken, Christine Iannaccone, Nancy A. Shadick, Michael Weinblatt, and Maura D. Iversen

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Paucity of Intact Non-Induced Provirus with Early, Long-Term Antiretroviral Therapy of Perinatal HIV Infection, Kaitlin Rainwater-Lovett, Carrie Ziemniak, Douglas Watson, Katherine Luzuriaga, George Siberry, Ann Petru, YaHui Chen, Priyanka Uprety, Margaret M. McManus, Ya-Chi Ho, Susanna L. Lamers, and Deborah Persaud

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Planning an innovation marathon at an infectious disease conference with results from the International Meeting on Emerging Diseases and Surveillance 2016 Hackathon, John W. Ramatowski, Christopher Xiang Lee, Aikaterini Mantzavino, Joao Ribas, Winter Guerra, Nicholas D. Preston, Eva Schernhammer, Lawrence C. Madoff, and Britta Lassmann

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Tuberculosis, human immunodeficiency virus, and the immune reconstitution inflammatory syndrome, Alwyn Rapose and S. Karande

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Alcohol and Cancer: Mechanisms and Therapies, Anuradha Ratna and Pranoti Mandrekar

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Clinical and demographic factors associated with change and maintenance of disease severity in a large registry of patients with rheumatoid arthritis, George W. Reed, David H. Collier, Andrew S. Koenig, Katherine C. Saunders, Dimitrios A. Pappas, Heather J. Litman, Joel M. Kremer, and Sameer Kotak

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On the Analysis of Intrahost and Interhost Viral Populations: Human Cytomegalovirus as a Case Study of Pitfalls and Expectations, Nicholas Renzette, Susanne P. Pfeifer, Sebastian Matuszewski, Timothy F. Kowalik, and Jeffrey D. Jensen

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Overexpressed somatic alleles are enriched in functional elements in Breast Cancer, Paula Restrepo, Mercedeh Movassagh, Nawaf Alomran, Christian Miller, Muzi Li, Chris Trenkov, Yulian Manchev, Sonali Bahl, Stephanie Warnken, Liam Spurr, Tatiyana Apanasovich, Keith Crandall, Nathan Edwards, and Anelia Horvath

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Environmental perturbations lead to extensive directional shifts in RNA processing, Allison L. Richards, Donovan Watza, Anthony Findley, Adnan Alazizi, Xiaoquan Wen, Athma A. Pai, Roger Pique-Regi, and Francesca Luca

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The Outcome of Thoracentesis versus Chest Tube Placement for Hepatic Hydrothorax in Patients with Cirrhosis: A Nationwide Analysis of the National Inpatient Sample, Ali Ridha, Yasir Al-Abboodi, and Matthew J. Fasullo

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Possible type 1 diabetes risk prediction: Using ultrasound imaging to assess pancreas inflammation in the inducible autoimmune diabetes BBDR model, Frederick R. Roberts, Clinton Hupple, Elaine Norowski, Nicole C. Walsh, Natalia Przewozniak, Ken-Edwin Aryee, Filia M. Van Dessel, Agata Jurczyk, David M. Harlan, Dale L. Greiner, Rita Bortell, and Chaoxing Yang

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Alterations in mRNA 3' UTR Isoform Abundance Accompany Gene Expression Changes in Human Huntington's Disease Brains, Lindsay S. Romo, Ami Ashar-Patel, Edith L. Pfister, and Neil Aronin

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Role of Granulocyte-Macrophage Colony-Stimulating Factor Production by T Cells during Mycobacterium tuberculosis Infection, Alissa C. Rothchild, Britni L. Stowell, Girija Goyal, Claudio Nunes-Alves, Qianting Yang, Kadamba Papavinasasundaram, Christopher M. Sassetti, Glenn Dranoff, Xinchun Chen, Jinhee Lee, and Samuel M. Behar

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ALS-linked FUS exerts a gain of toxic function involving aberrant p38 MAPK activation, Reddy Ranjith Kumar Sama, Claudia Fallini, Rodolfo Gatto, Jeanne E. McKeon, Yuyu Song, Melissa S. Rotunno, Saul Penaranda, Izrail Abdurakhmanov, John E. Landers, Gerardo Morfini, Scott T. Brady, and Daryl Bosco

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Cellular Differentiation of Human Monocytes Is Regulated by Time-Dependent Interleukin-4 Signaling and the Transcriptional Regulator NCOR2, Jil Sander, Eicke Latz, and Andreas Schlitzer

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Beta-Blocker Use Is Associated With Impaired Left Atrial Function in Hypertension, Mayank Sardana, Amer Ahmed Syed, Zeba Hashmath, Timothy S. Phan, Maheswara R. Koppula, Uzma Kewan, Zoubair Ahmed, Ravikantha Chandamuri, Swapna Varakantam, Ejaz Shah, Ryan Gorz, Scott R. Akers, and Julio A. Chirinos

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Long-term cardiovascular mortality after radiotherapy for breast cancer: A systematic review and meta-analysis, Partha Sardar, Amartya Kundu, Saurav Chatterjee, Anju Nohria, Ramez Nairooz, Sripal Bangalore, Debabrata Mukherjee, Wilbert S. Aronow, and Carl J. Lavie

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Microglia in Alzheimer's disease, Heela Sarlus and Michael T. Heneka

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Patient safety during procedural sedation using capnography monitoring: a systematic review and meta-analysis, Rhodri Saunders, Michel M.R.F. Struys, Richard F. Pollock, Michael Mestek, and Jenifer R. Lightdale

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Targeted Genetic Screen in Amyotrophic Lateral Sclerosis Reveals Novel Genetic Variants with Synergistic Effect on Clinical Phenotype, Pamela J. Shaw, Kevin P. Kenna, and John E. Landers

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Acute Appendicitis after Liver Transplantation: A Case Report and Review of the Literature, S. E. Sheppard, Hazel Marecki, Charles M. Psoinos, Babak Movahedi, Matthew J. Furman, Adel Bozorgzadeh, and Paulo N.A. Martins

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miRNAs cooperate in apoptosis regulation during C. elegans development, Ryan Sherrard, Sebastian Luehr, Heinke Holzkamp, Katherine McJunkin, Nadin Memar, and Barbara Conradt

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Atomistic structural ensemble refinement reveals non-native structure stabilizes a sub-millisecond folding intermediate of CheY, Jade Shi, R Paul. Nobrega, Christian Schwantes, Sagar V. Kathuria, Osman Bilsel, C. Robert Matthews, T J. Lane, and Vijay S. Pande

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Comprehensive genomic sequencing detects important genetic differences between right-sided and left-sided colorectal cancer, Yoshifumi Shimada, Stephen Lyle, Kazuaki Takabe, and Toshifumi Wakai

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Utility of comprehensive genomic sequencing for detecting HER2-positive colorectal cancer, Yoshifumi Shimada, Stephen Lyle, and Toshifumi Wakai

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Transient expression of ZBTB32 in anti-viral CD8+ T cells limits the magnitude of the effector response and the generation of memory, HyunMu Shin, Varun N. Kapoor, Gwanghun Kim, Peng Li, Hang-Rae Kim, M. Suresh, Susan M. Kaech, E. John Wherry, Liisa K. Selin, Warren J. Leonard, Raymond M. Welsh, and Leslie J. Berg

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Essential role for non-canonical poly(A) polymerase GLD4 in cytoplasmic polyadenylation and carbohydrate metabolism, Jihae Shin, Ki Young Paek, Mariya Ivshina, Emily E. Stackpole, and Joel D. Richter

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Mantle Cell Lymphoma in the Thyroid: A Rare Presentation, Uzma Mohammad Siddiqui, Sarika N. Rao, Pallavi K. Galera, Nahida Islam, and Mira S. Torres

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When Breath Becomes Air [book review], Hugh Silk

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A two-state comparative implementation of peer-support intervention to link veterans to health-related services after incarceration: a study protocol, Molly M. Simmons, Benjamin G. Fincke, Mari-Lynn Drainoni, Bo Kim, Tom Byrne, David A. Smelson, Kevin Casey, Marsha Langer Ellison, Christy Visher, Jessica Blue-Howells, and D. Keith McInnes

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A Hybrid III stepped wedge cluster randomized trial testing an implementation strategy to facilitate the use of an evidence-based practice in VA Homeless Primary Care Treatment Programs, Molly M. Simmons, Sonya Gabrielian, Thomas Hugh Byrne, Megan B. McCullough, Jeffery L. Smith, Thom J. Taylor, Thomas P. O'Toole, Vincent Kane, Vera Yakovchenko, D. Keith McInnes, and David A. Smelson

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Broad TCR repertoire and diverse structural solutions for recognition of an immunodominant CD8+ T cell epitope, InYoung Song, Anna Gil, Rabinarayan Mishra, Dario Ghersi, Liisa K. Selin, and Lawrence J. Stern

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Study protocol for Smartphone Monitoring for Atrial fibrillation in Real-Time in India (SMART-India): a community-based screening and referral programme, Apurv Soni, Nisha Fahey, Shyamsundar Raithatha, Anna Handorf, John Bostrom, Ravi Shah, Robert J. Goldberg, Jeroan J. Allison, and David D. McManus

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Vaccination with Recombinant Cryptococcus Proteins in Glucan Particles Protects Mice against Cryptococcosis in a Manner Dependent upon Mouse Strain and Cryptococcal Species, Charles A. Specht, Chrono K. Lee, Haibin Huang, Maureen M. Hester, Jianhua Liu, Bridget A. Luckie, Melanie A. Torres Santana, Zeynep Mirza, Payam Khoshkenar, Ambily Abraham, Zu T. Shen, Ali Akalin, Gary R. Ostroff, and Stuart M. Levitz

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Physical and psychosomatic health outcomes in people bereaved by suicide compared to people bereaved by other modes of death: a systematic review, Ailbhe Spillane, Celine Larkin, Paul Corcoran, Karen Matvienko-Sikar, Fiona Riordan, and Ella Arensman

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Qualitative Exploration of Cross-Sector Perspectives on the Contributions of Local Health Departments in Land-Use and Transportation Policy, Meera Sreedhara, Karin V. Goins, Semra A. Aytur, Rodney Lyn, Jay E. Maddock, Robin Riessman, Thomas L. Schmid, Heather Wooten, and Stephenie C. Lemon

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Association Between Leukocyte Telomere Length and the Risk of Incident Atrial Fibrillation: The Framingham Heart Study, Laila Staerk, Biqi Wang, Kathryn L. Lunetta, Robert H. Helm, Darae Ko, Jason A. Sherer, Patrick T. Ellinor, Steven A. Lubitz, David D. McManus, Ramachandran S. Vasan, Emelia J. Benjamin, and Ludovic Trinquart

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Guidelines for morpholino use in zebrafish, Didier Y. R. Stainier, Nathan D. Lawson, and Cecilia B. Moens

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Prevalence of, and Resident and Facility Characteristics Associated With Antipsychotic Use in Assisted Living vs. Long-Term Care Facilities: A Cross-Sectional Analysis from Alberta, Canada, Kathryn J. Stock, Joseph E. Amuah, Kate L. Lapane, David B. Hogan, and Colleen J. Maxwell

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Induced Remodeling of Porcine Tendons to Human Anterior Cruciate Ligaments by alpha-GAL Epitope Removal and Partial Cross-Linking, Kevin R. Stone, Ann Walgenbach, and Uri Galili

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Sodium channel NaV1.3 is important for enterochromaffin cell excitability and serotonin release, Peter R. Strege, Kaitlyn Knutson, Samuel J. Eggers, Joyce H. Li, Fan Wang, David Linden, Joseph H. Szurszewski, Lorin Milescu, Andrew B. Leiter, Gianrico Farrugia, and Arthur Beyder

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Child contact management in high tuberculosis burden countries: A mixed-methods systematic review, Daria Szkwarko, Yael Hirsch-Moverman, Lienki Du Plessis, Karen Du Preez, Catherine W. Carr, and Anna M. Mandalakas

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Brain microvasculature defects and Glut1 deficiency syndrome averted by early repletion of the glucose transporter-1 protein, Maoxue Tang, Guangping Gao, Huapeng Li, Qin Su, Darryl C. De Vivo, and Umrao R. Monani

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Risk of Gastrointestinal Bleeding Among Dabigatran Users - A Self Controlled Case Series Analysis, Wenze Tang, Hsien-Yen Chang, Meijia Zhou, and Sonal Singh

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Atorvastatin Promotes Phagocytosis and Attenuates Pro-Inflammatory Response in Human Retinal Pigment Epithelial Cells, Bo Tian, Ahmad Al-Moujahed, Peggy Bouzika, Yijun Hu, Shoji Notomi, Pavlina Tsoka, Joan W. Miller, Haijiang Lin, and Demetrios G. Vavvas

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Circumstances of fall-related injuries by age and gender among community-dwelling adults in the United States, Lava R. Timsina, Joanna L. Willetts, Melanye J. Brennan, Helen Marucci-Wellman, David A. Lombardi, Theodore K. Courtney, and Santosh K. Verma

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The association of dietary quality with colorectal cancer among normal weight, overweight and obese men and women: a prospective longitudinal study in the USA, Rosalie A. Torres Stone, Molly E. Waring, Sarah L. Cutrona, Catarina I. Kiefe, Jeroan J. Allison, and Chyke A. Doubeni

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A state-wide initiative to promote genetic testing in an underserved population, Meghan L. Underhill, Traci M. Blonquist, Karleen Habin, Debra Lundquist, Kristen Shannon, Kathryn Robinson, Mary-Lou Woodford, and Jean Boucher

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Paternal nicotine exposure alters hepatic xenobiotic metabolism in offspring, Markus P. Vallaster, Shweta Kukreja, Xin Y. Bing, Jennifer Ngolab, Rubing Zhao-Shea, Paul D. Gardner, Andrew R. Tapper, and Oliver J. Rando

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Effect of weather on pedestrian trip count and duration: City-scale evaluations using mobile phone application data, Anthony P. Vanky, Santosh K. Verma, Theodore K. Courtney, Paolo Santi, and Carlo Ratti

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Anatomic humeral head replacement with a press-fit prosthesis: An in vivo radiographic study, Bryan Vopat, Jeremy Truntzer, Daniel Aaron, Jack Anavian, Joel Schwartz, and Andrew Green

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Humanized Mouse Models of Clinical Disease, Nicole C. Walsh, Laurie L. Kenney, Sonal Jangalwe, Ken-Edwin Aryee, Dale L. Greiner, Michael A. Brehm, and Leonard D. Shultz

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Microvascular response to transfusion in elective spine surgery, J. Matthias Walz, Ottokar Stundner, Federico P. Girardi, Bruce A. Barton, Aimee R. Kroll-Desrosiers, Stephen O. Heard, and Stavros G. Memtsoudis

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MKP-1 suppresses PARP-1 degradation to mediate cisplatin resistance, J. Wang, D. H. Kho, J-Y Zhou, Roger J. Davis, and G. S. Wu

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Clinic Versus Online Social Network-Delivered Lifestyle Interventions: Protocol for the Get Social Noninferiority Randomized Controlled Trial, Monica L. Wang, Molly E. Waring, Danielle E. Jake-Schoffman, Jessica L. Oleski, Zachary Michaels, Jared M. Goetz, Stephenie C. Lemon, Yunsheng Ma, and Sherry L. Pagoto

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Screening of primary gp120 immunogens to formulate the next generation polyvalent DNA prime-protein boost HIV-1 vaccines, Shixia Wang, Te-Hui Chou, Anthony Hackett, Veronica Efros, Yan Wang, Dong Han, Aaron Wallace, Yuxin Chen, Guangnan Hu, Shuying Liu, Paul R. Clapham, James Arthos, David Montefiori, and Shan Lu

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Resting-state functional connectivity changes within the default mode network and the salience network after antipsychotic treatment in early-phase schizophrenia, Yingchan Wang, Weijun Tang, Xiaoduo Fan, Jianye Zhang, Daoying Geng, Kaida Jiang, Dianming Zhu, Zhenhua Song, Zeping Xiao, and Dengtang Liu

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Computational Investigation of Homologous Recombination DNA Repair Deficiency in Sporadic Breast Cancer, Yue Wang, Matthew H. Ung, Sharon B. Cantor, and Chao Cheng

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Metformin inhibits the proliferation of benign prostatic epithelial cells, Zongwei Wang, Xingyuan Xiao, Rongbin Ge, Jijun Li, Cameron W. Johnson, Cyrus Rassoulian, and Aria F. Olumi

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Altitude-Related Change in Endotracheal Tube Cuff Pressures in Helicopter EMS, Stacy Weisberg, Jonathan C. McCall Jr, and Joseph Tennyson

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Modulation of let-7 miRNAs controls the differentiation of effector CD8 T cells, Alexandria C. Wells, Keith A. Daniels, Constance C. Angelou, Eric Fagerberg, Amy S. Burnside, Michele Markstein, Dominique Alfandari, Raymond M. Welsh, Elena L. Pobezinskaya, and Leonid A. Pobezinsky

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Germinal centre frequency is decreased in pancreatic lymph nodes from individuals with recent-onset type 1 diabetes, Abby Willcox, Sarah J. Richardson, Lucy S. K. Walker, Sally C. Kent, Noel G. Morgan, and Kathleen M. Gillespie

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Chromatin dynamics regulate mesenchymal stem cell lineage specification and differentiation to osteogenesis, Hai Wu, Jonathan A. Gordon R, Troy W. Whitfield, Phillip W. Tai L, Andre J. van Wijnen, Janet L. Stein, Gary S. Stein, and Jane B. Lian

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The Dopamine Transporter Recycles via a Retromer-Dependent Postendocytic Mechanism: Tracking Studies Using a Novel Fluorophore-Coupling Approach, Sijia Wu, Rita R. Fagan, Chayasith Uttamapinant, Lawrence M. Lifshitz, Kevin E. Fogarty, Alice Y. Ting, and Haley Melikian

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Infection rates in patients from five rheumatoid arthritis (RA) registries: contextualising an RA clinical trial programme, Hisashi Yamanaka and George W. Reed

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INTU is essential for oncogenic Hh signaling through regulating primary cilia formation in basal cell carcinoma, N. Yang, E. L.-H. Leung, C. Liu, L. Li, Thibaut Eguether, X.-J. Jun Yao, E. C. Jones, D. A. Norris, A. Liu, R. A. Clark, D. R. Roop, Gregory J. Pazour, K. R. Shroyer, and J. Chen

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(CCUG)n RNA toxicity in a Drosophila model of myotonic dystrophy type 2 (DM2) activates apoptosis, Vildan Betul Yenigun, Mario Sirito, Alla Amcheslavsky, Tomek Czernuszewicz, Jordi Colonques-Bellmunt, Irma Garcia-Alcover, Marzena Wojciechowska, Clare Bolduc, Zhihong Chen, Arturo Lopez Castel, Ralf Krahe, and Andreas Bergmann

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Evidence that C9ORF72 Dipeptide Repeat Proteins Associate with U2 snRNP to Cause Mis-splicing in ALS/FTD Patients, Shanye Yin, Rodrigo Lopez-Gonzalez, Ryan C. Kunz, Jaya Gangopadhyay, Carl Borufka, Steven P. Gygi, Fen-Biao Gao, and Robin Reed

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Bivalent Epigenetic Control of Oncofetal Gene Expression in Cancer, Sayyed K. Zaidi, Seth E. Frietze, Jonathan A. Gordon, Jessica L. Heath, Terri Messier, Deli Hong, Joseph R. Boyd, Mingu Kang, Anthony N. Imbalzano, Jane B. Lian, Janet L. Stein, and Gary S. Stein

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Lower school performance in late chronotypes: underlying factors and mechanisms, Giulia Zerbini, Vincent van der Vinne, Lana K. M. Otto, Thomas Kantermann, Wim P. Krijnen, Till Roenneberg, and Martha Merrow

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The Association between Breakfast Skipping and Body Weight, Nutrient Intake, and Metabolic Measures among Participants with Metabolic Syndrome, Lijuan Zhang, Lorraine S. Cordeiro, Jinghua Liu, and Yunsheng Ma

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Predicting human splicing branchpoints by combining sequence-derived features and multi-label learning methods, Wen Zhang, Xiaopeng Zhu, Yu Fu, Junko Tsuji, and Zhiping Weng

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Intraflagellar transporter protein (IFT27), an IFT25 binding partner, is essential for male fertility and spermiogenesis in mice, Yong Zhang, Hong Liu, Wei Li, Zhengang Zhang, Xuejun Shang, David Zhang, Yuhong Li, Shiyang Zhang, Junpin Liu, Rex A. Hess, Gregory J. Pazour, and Zhibing Zhang