UMMS Affiliation

School of Medicine

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Document Type



Immune System Diseases | Plastic Surgery | Skin and Connective Tissue Diseases


Bullous pemphigoid is an autoimmune blistering disease where patients suffer from painful bullae, often covering large portions of the skin and requiring management with immune-suppression. Our case report of recurring bullous pemphigoid illustrates the importance of considering immunosuppressive perioperative management in patients with a history of autoimmune blistering even when the disease has been quiescent for some time. With multidisciplinary care and immune suppressive therapies in the perioperative period, a free flap complicated by recurrent bullous pemphigoid can be salvaged.


bullous pemphigoid, bullae, case report, immunosuppressive perioperative management, immune suppressive therapies

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Copyright © 2021 The Authors. Published by Wolters Kluwer Health, Inc. on behalf of The American Society of Plastic Surgeons. This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License 4.0 (CCBY-NC-ND), where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially without permission from the journal.

DOI of Published Version



Pollock SE, Rice SM, Ferree SD, Friedstat J, Eberlin K, Kourosh AS. Lower Extremity Salvage in the Setting of Bullous Pemphigoid Exacerbation: A Case Report. Plast Reconstr Surg Glob Open. 2021 Aug 5;9(8):e3722. doi: 10.1097/GOX.0000000000003722. PMID: 34476147; PMCID: PMC8395591. Link to article on publisher's site

Journal/Book/Conference Title

Plastic and reconstructive surgery. Global open

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Creative Commons License

Creative Commons Attribution-Noncommercial-No Derivative Works 4.0 License
This work is licensed under a Creative Commons Attribution-Noncommercial-No Derivative Works 4.0 License.