UMMS Affiliation

Department of Medicine

Publication Date


Document Type



Endocrine System Diseases | Internal Medicine | Nutritional and Metabolic Diseases | Primary Care | Virus Diseases


Chronic hepatitis C (CHC) is associated with a higher risk of developing type 2 diabetes mellitus (DM). In patients with preexisting type 2 DM, CHC often worsens glycemic control. With direct-acting antivirals (DAAs)-based treatment regimens for CHC, nearly all patients achieve sustained virologic response (SVR). There is limited literature demonstrating improvement in the glycemic index of patients with DM following the eradication of hepatitis C virus (HCV) with DAA. Thus, it is reasonable to hypothesize that early treatment of CHC and optimal glycemic control in these patients could prevent chronic complications of diabetes and worsening of liver disease. We performed a retrospective cohort study examining whether HCV eradication with DAAs leads to improved glycemic index in patients with DM and the feasibility of safely and successfully offering such care at a primary care physician/providers (PCP) office.


Hepatitis C, diabetes mellitus

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Copyright © 2021 The Author(s). This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial License (, which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

DOI of Published Version



Tripathi K, Loganathan S, Trivedi N, Abraham GM. Impact of hepatitis C remission on glycemic control in patients with type 2 diabetes mellitus: primary care outpatient experience. J Community Hosp Intern Med Perspect. 2021 May 10;11(3):354-356. doi: 10.1080/20009666.2021.1886631. PMID: 34234905; PMCID: PMC8118393. Link to article on publisher's site

Journal/Book/Conference Title

Journal of community hospital internal medicine perspectives

Related Resources

Link to Article in PubMed

PubMed ID


Creative Commons License

Creative Commons Attribution-Noncommercial 4.0 License
This work is licensed under a Creative Commons Attribution-Noncommercial 4.0 License