UMMS Affiliation

Department of Medicine, Division of Cardiovascular Medicine; Department of Surgery

Publication Date


Document Type



Cardiology | Cardiovascular Diseases | Diagnosis | Male Urogenital Diseases | Surgery


Vas deferens calcification is a chronic arterio-sclerotic process that develops over many years and is strongly associated with infertility. Incidental findings on imaging are the most common means of diagnosing this condition. We report a case of a 56-year man who likely has male factor infertility and was found to have bilateral vas deferens calcification on CT imaging. This was performed during pre-procedural workup for transcatheter aortic valve replacement (TAVR) for management of severe aortic stenosis (AS). The patient was also had severe calcific multi-vessel coronary artery disease requiring percutaneous coronary intervention with atherectomy. This case highlights a novel clinical association linking infertility with coronary and valvular heart disease. It is possible that this association exists in larger numbers than previously recognized. Closer monitoring of pelvic imaging for TAVR access planning in patients with severe AS may bring more cases to light.


Vas Deferens Calcification, aortic Stenosis, coronary Artery Disease

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© 2021 The Author(s). This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial License (, which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

DOI of Published Version



Kundu A, Ogunsua AA, Walker J, Qureshi WT, Kakouros N. Bilateral vas deferens calcification in a patient with multi-vessel coronary artery disease and severe aortic stenosis: linking infertility with cardiovascular disease. J Community Hosp Intern Med Perspect. 2021 May 10;11(3):376-378. doi: 10.1080/20009666.2021.1898085. PMID: 34234910; PMCID: PMC8118445. Link to article on publisher's site

Journal/Book/Conference Title

Journal of community hospital internal medicine perspectives

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PubMed ID


Creative Commons License

Creative Commons Attribution-Noncommercial 4.0 License
This work is licensed under a Creative Commons Attribution-Noncommercial 4.0 License