UMMS Affiliation

Department of Medicine, Division of Infectious Diseases and Immunology

Publication Date


Document Type



Fungi | Microbiology


Invasive mold infections caused by molds other than Aspergillus spp. or Mucorales are emerging. The reported prevalences of infection due to these rare fungal pathogens vary among geographic regions, driven by differences in climatic conditions, susceptible hosts, and diagnostic capabilities. These rare molds-Fusarium, Lomentospora, and Scedosporium species and others-are difficult to detect and often show intrinsic antifungal resistance. Now, international societies of medical mycology and microbiology have joined forces and created the "Global guideline for the diagnosis and management of rare mould infections: an initiative of the European Confederation of Medical Mycology in cooperation with the International Society for Human and Animal Mycology and the American Society for Microbiology" (published in Lancet Infect Dis,, with the goal of improving the diagnosis, treatment, prevention, and survival of persons with rare mold infections. The guideline provides cutting-edge guidance for the correct utilization and application of established and new diagnostic and therapeutic options.


Fusarium, Lomentospora, Paecilomyces, Penicillium, Phaeohyphomycosis, Rasamsonia, Scedosporium, Scopulariopsis, basidiomycetes, diagnosis, molds, treatment

Rights and Permissions

©2021 Hoenigl et al. This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International license.

DOI of Published Version



Hoenigl M, Levitz SM, Schuetz AN, Zhang SX, Cornely OA. All You Need to Know and More about the Diagnosis and Management of Rare Mold Infections. mBio. 2021 Feb 23;12(1):e02920-20. doi: 10.1128/mBio.02920-20. PMID: 33622731. Link to article on publisher's site

Journal/Book/Conference Title


Related Resources

Link to Article in PubMed

PubMed ID


Creative Commons License

Creative Commons Attribution 4.0 License
This work is licensed under a Creative Commons Attribution 4.0 License.