Identifying Opioid Withdrawal Using Wearable Biosensors

UMMS Affiliation

Department of Emergency Medicine

Publication Date


Document Type

Conference Proceeding


Artificial Intelligence and Robotics | Biomedical Devices and Instrumentation | Substance Abuse and Addiction | Telemedicine


Wearable biosensors can be used to monitor opioid use, a problem of dire societal consequence given the current opioid epidemic in the US. Such surveillance can prompt interventions that promote behavioral change. Prior work has focused on the use of wearable biosensor data to detect opioid use. In this work, we present a method that uses machine learning to identify opioid withdrawal using data collected with a wearable biosensor. Our method involves developing a set of machine-learning classifiers, and then evaluating those classifiers using unseen test data. An analysis of the best performing model (based on the Random Forest algorithm) produced a receiver operating characteristic (ROC) area under the curve (AUC) of 0.9997 using completely unseen test data. Further, the model is able to detect withdrawal with just one minute of biosensor data. These results show the viability of using machine learning for opioid withdrawal detection. To our knowledge, the proposed method for identifying opioid withdrawal in OUD patients is the first of its kind.


opioid withdrawal, wearable biosensors, machine learning


Kulman E, Chapman B, Venkatasubramanian K, Carreiro S. Identifying Opioid Withdrawal Using Wearable Biosensors. Proc Annu Hawaii Int Conf Syst Sci. 2021 Jan;54:3583-3592. PMID: 33568965; PMCID: PMC7871978.

Journal/Book/Conference Title

Proceedings of the ... Annual Hawaii International Conference on System Sciences. Annual Hawaii International Conference on System Sciences

Related Resources

Link to Article in PubMed

PubMed ID