UMMS Affiliation

Program in Innate Immunity, Division of Infectious Diseases and Immunology, Department of Medicine; Graduate School of Biomedical Sciences

Publication Date

2020-10-08

Document Type

Article

Disciplines

Bacterial Infections and Mycoses | Cellular and Molecular Physiology | Immunity | Immunology of Infectious Disease | Pathogenic Microbiology

Abstract

Here, we discuss 5 concepts that have emerged in studies of metabolic and immune interactions in C. elegans. The major emerging theme is that the immune response and the ability to survive pathogen infection is heavily influenced by pathogen-induced changes in host metabolism.

Keywords

Caenorhabditis elegans, Pathogens, Mitochondria, Nematode infections, Fatty acids, Bacterial pathogens, Respiratory infections, Transcription factors

Rights and Permissions

Copyright: © 2020 Anderson, Pukkila-Worley. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

DOI of Published Version

10.1371/journal.ppat.1008897

Source

Anderson SM, Pukkila-Worley R. Immunometabolism in Caenorhabditis elegans. PLoS Pathog. 2020 Oct 8;16(10):e1008897. doi: 10.1371/journal.ppat.1008897. PMID: 33031414; PMCID: PMC7544110. Link to article on publisher's site

Journal/Book/Conference Title

PLoS pathogens

Related Resources

Link to Article in PubMed

PubMed ID

33031414

Creative Commons License

Creative Commons Attribution 4.0 License
This work is licensed under a Creative Commons Attribution 4.0 License.

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