UMMS Affiliation

Program in Innate Immunity, Division of Infectious Diseases and Immunology, Department of Medicine; Graduate School of Biomedical Sciences

Publication Date


Document Type



Bacterial Infections and Mycoses | Cellular and Molecular Physiology | Immunity | Immunology of Infectious Disease | Pathogenic Microbiology


Here, we discuss 5 concepts that have emerged in studies of metabolic and immune interactions in C. elegans. The major emerging theme is that the immune response and the ability to survive pathogen infection is heavily influenced by pathogen-induced changes in host metabolism.


Caenorhabditis elegans, Pathogens, Mitochondria, Nematode infections, Fatty acids, Bacterial pathogens, Respiratory infections, Transcription factors

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Copyright: © 2020 Anderson, Pukkila-Worley. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

DOI of Published Version



Anderson SM, Pukkila-Worley R. Immunometabolism in Caenorhabditis elegans. PLoS Pathog. 2020 Oct 8;16(10):e1008897. doi: 10.1371/journal.ppat.1008897. PMID: 33031414; PMCID: PMC7544110. Link to article on publisher's site

Journal/Book/Conference Title

PLoS pathogens

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PubMed ID


Creative Commons License

Creative Commons Attribution 4.0 License
This work is licensed under a Creative Commons Attribution 4.0 License.