UMMS Affiliation
Program in Innate Immunity, Division of Infectious Diseases and Immunology, Department of Medicine; Graduate School of Biomedical Sciences
Publication Date
2020-10-08
Document Type
Article
Disciplines
Bacterial Infections and Mycoses | Cellular and Molecular Physiology | Immunity | Immunology of Infectious Disease | Pathogenic Microbiology
Abstract
Here, we discuss 5 concepts that have emerged in studies of metabolic and immune interactions in C. elegans. The major emerging theme is that the immune response and the ability to survive pathogen infection is heavily influenced by pathogen-induced changes in host metabolism.
Keywords
Caenorhabditis elegans, Pathogens, Mitochondria, Nematode infections, Fatty acids, Bacterial pathogens, Respiratory infections, Transcription factors
Rights and Permissions
Copyright: © 2020 Anderson, Pukkila-Worley. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
DOI of Published Version
10.1371/journal.ppat.1008897
Source
Anderson SM, Pukkila-Worley R. Immunometabolism in Caenorhabditis elegans. PLoS Pathog. 2020 Oct 8;16(10):e1008897. doi: 10.1371/journal.ppat.1008897. PMID: 33031414; PMCID: PMC7544110. Link to article on publisher's site
Journal/Book/Conference Title
PLoS pathogens
Related Resources
PubMed ID
33031414
Repository Citation
Anderson SM, Pukkila-Worley R. (2020). Immunometabolism in Caenorhabditis elegans. Open Access Publications by UMMS Authors. https://doi.org/10.1371/journal.ppat.1008897. Retrieved from https://escholarship.umassmed.edu/oapubs/4436
Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 License.
Included in
Bacterial Infections and Mycoses Commons, Cellular and Molecular Physiology Commons, Immunity Commons, Immunology of Infectious Disease Commons, Pathogenic Microbiology Commons