UMMS Affiliation

Department of Medicine, Division of Hematology Oncology

Publication Date


Document Type



Diagnosis | Digestive System Diseases | Hematology | Hemic and Lymphatic Diseases | Neoplasms | Oncology


Extramedullary myeloma, defined by presence of plasma cells outside the bone marrow, is a rare entity accounting for about 3-9% of all cases. It usually is aggressive with a median survival of < 6 months. It is also associated with adverse prognostic factors including 17p deletions and high-risk gene profiles. While common extramedullary sites include bones, there have been several case reports of hematogenous extramedullary myeloma to the liver, lungs, pancreas, breast, skin, and soft tissues. Extramedullary myeloma to the mesentery is a rare entity with only a handful of cases reported. We present a case of 69-year-old man presenting with relapse of multiple myeloma to the mesentery, resulting in bowel obstruction to highlight the various presentations of myeloma.


multiple myeloma, extramedullary myeloma, mesentery, bowel obstruction

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Copyright © 2019 Prarthna V. Bhardwaj et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

DOI of Published Version



Bhardwaj PV, Khanna S, Jawad MD, Ali SS. A Rare Case of Extramedullary Relapse of Multiple Myeloma Causing Bowel Obstruction. Case Rep Hematol. 2019 Apr 11;2019:4962678. doi: 10.1155/2019/4962678. PMID: 31110827; PMCID: PMC6487170. Link to article on publisher's site

Journal/Book/Conference Title

Case reports in hematology

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Link to Article in PubMed

PubMed ID


Creative Commons License

Creative Commons Attribution 4.0 License
This work is licensed under a Creative Commons Attribution 4.0 License.