UMMS Affiliation

Department of Psychiatry

Publication Date


Document Type



Analytical, Diagnostic and Therapeutic Techniques and Equipment | Biomedical Devices and Instrumentation | Cardiovascular Diseases | Circulatory and Respiratory Physiology | Health Information Technology


One in three adults worldwide has hypertension, which is associated with significant morbidity and mortality. Consequently, there is a global demand for continuous and non-invasive blood pressure (BP) measurements that are convenient, easy to use, and more accurate than the currently available methods for detecting hypertension. This could easily be achieved through the integration of single-site photoplethysmography (PPG) readings into wearable devices, although improved reliability and an understanding of BP estimation accuracy are essential. This review paper focuses on understanding the features of PPG associated with BP and examines the development of this technology over the 2010-2019 period in terms of validation, sample size, diversity of subjects, and datasets used. Challenges and opportunities to move single-site PPG forward are also discussed.


PPG signal, biomedical engineering, biomedical signal analysis, blood pressure measurement, digital health, digital medicine, hypertension assessment, hypertension diagnosis, photoplethysmogram, photoplethysmography, pulse oximetry, wearable devices, wearable technology

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© 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (

DOI of Published Version



Hosanee M, Chan G, Welykholowa K, Cooper R, Kyriacou PA, Zheng D, Allen J, Abbott D, Menon C, Lovell NH, Howard N, Chan WS, Lim K, Fletcher R, Ward R, Elgendi M. Cuffless Single-Site Photoplethysmography for Blood Pressure Monitoring. J Clin Med. 2020 Mar 7;9(3):E723. doi: 10.3390/jcm9030723. PMID: 32155976. Link to article on publisher's site

Journal/Book/Conference Title

Journal of clinical medicine


Full author list omitted for brevity. For the full list of authors, see article.

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PubMed ID


Creative Commons License

Creative Commons Attribution 4.0 License
This work is licensed under a Creative Commons Attribution 4.0 License.