Department of Surgery, Division of Thoracic Surgery
Health Economics | Health Policy | Insurance | Pharmaceutical Preparations | Pharmacoeconomics and Pharmaceutical Economics | Pharmacy Administration, Policy and Regulation
OBJECTIVE: To evaluate trends in the use of generic and non-generic medicines to treat hypertension and diabetes under the Farmacia Popular Program (FP) and its impact on generic medicines sales volume and market share in the Brazilian pharmaceutical market.
METHODS: This longitudinal, retrospective study used interrupted time series design to analyze changes in monthly sales volume and proportion of medicines sales (market share) for oral antidiabetic and antihypertensive medicines for generic versus non-generic products. Analyses were conducted in a combined dataset that aggregate monthly sales volumes from the Farmacia Popular program and from the QuintilesIMS (IQVIA) national market sales data from January 2007 to December 2012. The Farmacia Popular program phases analyzed included: a) 2009 reductions in medicines reference prices (AFP-II) and b) 2011 implementation of free medicines program for hypertension and diabetes, the Saude nao tem preco (SNTP - Health has no price).
RESULTS: Patterns of use for FP-covered antidiabetic and antihypertensive medicines were similar to their use in the market in general. After one year of the decreases in government subsidies in April 2010, market share of antidiabetic and antihypertensive medicines experienced relative declines of -54.5% and -59.9%, respectively. However, when FP-covered medicines were made free to patients, overall market volume for antidiabetic and antihypertensive generics increased dramatically, with 242.6% and 277.0% relative increases by February 2012, as well as non-generics with relative increase of 209.7% and 279% for antidiabetic and antihypertensive medicines, respectively.
CONCLUSIONS: Ministry of Health policies on the amount of patient cost sharing and on the choice of medicines on coverage lists have substantial impacts on overall generic sales volume in retail pharmacies.
Generic Drugs; Generic Drug Policy; Antihypertensive Agents; Hypoglycemic Agents
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DOI of Published Version
Rev Saude Publica. 2019 Oct 17;53:94. doi: 10.11606/s1518-8787.2019053001237. eCollection 2019. Link to article on publisher's site
Revista de saude publica
Bertoldi AD, Chaves LA, Ross-Degnan D, Luiza VL, Emmerick IC, Mendes da Silva R, Campos MR. (2019). Brazilian generics market change after Farmacia Popular program. Open Access Publications by UMMS Authors. https://doi.org/10.11606/s1518-8787.2019053001237. Retrieved from https://escholarship.umassmed.edu/oapubs/4029
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This work is licensed under a Creative Commons Attribution 4.0 License.
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