UMMS Affiliation

Department of Surgery, Division of Organ Transplantation; Department of Pathology; Department of Medicine, Division of Renal Medicine/Nephrology; Department of Urology

Publication Date

2019-10-01

Document Type

Article

Disciplines

Female Urogenital Diseases and Pregnancy Complications | Male Urogenital Diseases | Neoplasms | Nephrology | Surgery | Surgical Procedures, Operative | Urogenital System | Urology

Abstract

With the rising incidence of end-stage renal disease in the United States, patients needing renal transplants are waiting longer for increasingly scarce grafts. Formerly, the general practice was to avoid organs with tumors for transplant because of the risk of malignancy transmission to the recipient. However, with comprehensive donor selection and a small-sized primary tumor, the positive outcomes of transplant outweigh the risks of transmission after a partial nephrectomy. In our case, a 31-year-old woman, the daughter of the recipient, underwent a laparoscopic nephrectomy with an existing 8-mm tumor later confirmed as renal cell carcinoma. An ex vivo tumor enucleation was performed before the allograft was transplanted into the 69-year-old patient with endstage renal disease. At last follow-up, graft function has remained excellent with no evidence of local recurrence or metastasis in both the donor and recipient. Here, we describe our case and perform a literature review on the incidence and management of renal allografts with incidentally detected renal cell carcinoma during transplant.

Keywords

Kidney transplantation, Kidney masses, Living donor

Rights and Permissions

Copyright © Baskent University 2019

DOI of Published Version

10.6002/ect.2018.0215

Source

Exp Clin Transplant. 2019 Oct 1. doi: 10.6002/ect.2018.0215. [Epub ahead of print] Link to article on publisher's site

Journal/Book/Conference Title

Experimental and clinical transplantation : official journal of the Middle East Society for Organ Transplantation

Related Resources

Link to Article in PubMed

PubMed ID

31580237

Share

COinS
 
 

To view the content in your browser, please download Adobe Reader or, alternately,
you may Download the file to your hard drive.

NOTE: The latest versions of Adobe Reader do not support viewing PDF files within Firefox on Mac OS and if you are using a modern (Intel) Mac, there is no official plugin for viewing PDF files within the browser window.