UMMS Affiliation
Department of Quantitative Health Sciences, Outcomes Measurement Science
Publication Date
2019-1
Document Type
Article
Disciplines
Clinical Epidemiology | Epidemiology | Health Services Research | Neoplasms | Statistics and Probability
Abstract
OBJECTIVE: The computer-adaptive test (CAT) of the European Organisation for Research and Treatment of Cancer (EORTC), the EORTC CAT Core, assesses the same 15 domains as the EORTC QLQ-C30 health-related quality of life questionnaire but with increased precision, efficiency, measurement range and flexibility. CAT parameters for estimating scores have been established based on clinical data from cancer patients. This study aimed at establishing the European Norm for each CAT domain based on general population data.
METHODS: We collected representative general population data across 11 European Union (EU) countries, Russia, Turkey, Canada and the United States (n > /= 1000/country; stratified by sex and age). We selected item subsets from each CAT domain for data collection (totalling 86 items). Differential item functioning (DIF) analyses were conducted to investigate cross-cultural measurement invariance. For each domain, means and standard deviations from the EU countries (weighted by country population, sex and age) were used to establish a T-metric with a European general population mean = 50 (standard deviation = 10).
RESULTS: A total of 15,386 respondents completed the online survey (n = 11,343 from EU countries). EORTC CAT Core norm scores for all 15 countries were calculated. DIF had negligible impact on scoring. Domain-specific T-scores differed significantly across countries with small to medium effect sizes.
CONCLUSION: This study establishes the official European Norm for the EORTC CAT Core. The European CAT Norm can be used globally and allows for meaningful interpretation of scores. Furthermore, CAT scores can be compared with sex- and age-adjusted norm scores at a national level within each of the 15 countries.
Keywords
Computer-adaptive test, EORTC CAT Core, General population, Item response theory, Norm data, Normative data, Patient-reported outcomes, Quality of life, Self-report, Survey
Rights and Permissions
Copyright 2018 The Authors. This is an open access article under the CC BY-NC-ND license (http:// creativecommons.org/licenses/by-nc-nd/4.0/).
DOI of Published Version
10.1016/j.ejca.2018.11.023
Source
Eur J Cancer. 2019 Jan;107:133-141. doi: 10.1016/j.ejca.2018.11.023. Epub 2018 Dec 18. Link to article on publisher's site
Journal/Book/Conference Title
European journal of cancer (Oxford, England : 1990)
Related Resources
PubMed ID
30576969
Repository Citation
Liegl G, Petersen MA, Groenvold M, Aaronson NK, Costantini A, Fayers PM, Holzner B, Johnson CD, Kemmler G, Tomaszewski KA, Waldmann A, Young TE, Rose MS, Nolte S. (2019). Establishing the European Norm for the health-related quality of life domains of the computer-adaptive test EORTC CAT Core. Open Access Articles. https://doi.org/10.1016/j.ejca.2018.11.023. Retrieved from https://escholarship.umassmed.edu/oapubs/3700
Creative Commons License
This work is licensed under a Creative Commons Attribution-Noncommercial-No Derivative Works 4.0 License.
Included in
Clinical Epidemiology Commons, Epidemiology Commons, Health Services Research Commons, Neoplasms Commons, Statistics and Probability Commons