Treatment of Triple-Negative Breast Cancer Cells with the Canady Cold Plasma Conversion System: Preliminary Results
Authors
Cheng, XiaoqianRowe, Warren
Ly, Lawan
Shashurin, Alexey
Zhuang, Taisen
Wigh, Shruti
Basadonna, Giacomo
Trink, Barry
Keidar, Michael
Canady, Jerome
UMass Chan Affiliations
Department of SurgeryDocument Type
Journal ArticlePublication Date
2018-09-15Keywords
triple-negative breast cancercold atmospheric plasma
cold plasma device
Biotechnology
Cancer Biology
Fluids and Secretions
Neoplasms
Therapeutics
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Show full item recordAbstract
Triple-negative breast cancer is a phenotype of breast cancer where the expression level of estrogen, progesterone and human epidermal growth factor receptor 2 (HER2) receptors are low or absent. It is more frequently diagnosed in younger and premenopausal women, among which African and Hispanic have a higher rate. Cold atmospheric plasma has revealed its promising ant-cancer capacity over the past two decades. In this study, we report the first cold plasma jet delivered by the Canady Cold Plasma Conversion Unit and characterization of its electric and thermal parameters. The unit effectively reduced the viability of triple-negative breast cancer up to 80% without thermal damage, providing a starting point for future clinical trials.Source
Cheng, X.; Rowe, W.; Ly, L.; Shashurin, A.; Zhuang, T.; Wigh, S.; Basadonna, G.; Trink, B.; Keidar, M.; Canady, J. Treatment of Triple-Negative Breast Cancer Cells with the Canady Cold Plasma Conversion System: Preliminary Results. Plasma 2018, 1, 218-228. https://doi.org/10.3390/plasma1010019
DOI
10.3390/plasma1010019Permanent Link to this Item
http://hdl.handle.net/20.500.14038/40783Rights
© 2018 by the authors. Licensee MDPI, Basel, Switzerland. This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited (CC BY 4.0).Distribution License
http://creativecommons.org/licenses/by/4.0/ae974a485f413a2113503eed53cd6c53
10.3390/plasma1010019
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Except where otherwise noted, this item's license is described as © 2018 by the authors. Licensee MDPI, Basel, Switzerland. This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited (CC BY 4.0).