Department of Quantitative Health Sciences; Meyers Primary Care Institute; Division of Geriatrics, Department of Medicine; Division of Cardiovascular Medicine, Department of Medicine
Cardiology | Cardiovascular Diseases | Clinical Epidemiology | Epidemiology | Geriatrics | Health Services Research | Pathological Conditions, Signs and Symptoms
BACKGROUND: To examine age-specific differences in the frequency and impact of cardiac and non-cardiac conditions among patients aged 65years and older hospitalized with acute myocardial infarction (AMI).
METHODS: Study population consisted of 3863 adults hospitalized with AMI at 11 medical centers in central Massachusetts on a biennial basis between 2001 and 2011. The presence of 11 chronic conditions (five cardiac and six non-cardiac) was based on the review of hospital medical records.
RESULTS: Participants' median age was 79years, 49% were men, and had an average of three chronic conditions (average of cardiac conditions: 2.6 and average of non-cardiac conditions: 1.0). Approximately one in every two patients presented with two or more cardiac related conditions whereas one in every three patients presented with two or more non-cardiac related conditions. The most prevalent chronic conditions in our study population were hypertension, diabetes, heart failure, chronic kidney disease, and peripheral vascular disease. Patients across all age groups with a greater number of previously diagnosed cardiac or non-cardiac conditions were at higher risk for developing important clinical complications or dying during hospitalization as compared to those with 0-1 condition.
CONCLUSIONS: The prevalence of multimorbidity among older adults hospitalized with AMI is high and associated with worse outcomes that should be considered in the management of this vulnerable population.
UMCCTS funding, Multiple chronic conditions, Myocardial infarction
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© 2018 The Authors. Published by Elsevier B.V. This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
DOI of Published Version
Int J Cardiol. 2018 Dec 1;272:341-345. doi: 10.1016/j.ijcard.2018.08.062. Epub 2018 Aug 22. Link to article on publisher's site
International journal of cardiology
Tisminetzky M, Nguyen HL, Gurwitz JH, McManus DD, Gore JM, Singh S, Yarzebski JL, Goldberg RJ. (2018). Magnitude and impact of multiple chronic conditions with advancing age in older adults hospitalized with acute myocardial infarction. Open Access Articles. https://doi.org/10.1016/j.ijcard.2018.08.062. Retrieved from https://escholarship.umassmed.edu/oapubs/3572
Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 License.
Cardiology Commons, Cardiovascular Diseases Commons, Clinical Epidemiology Commons, Epidemiology Commons, Geriatrics Commons, Health Services Research Commons, Pathological Conditions, Signs and Symptoms Commons