International Stem Cell Registry; Department of Neurology
Cell Biology | Cells | Databases and Information Systems | Laboratory and Basic Science Research
Unambiguous cell line authentication is essential to avoid loss of association between data and cells. The risk for loss of references increases with the rapidity that new human pluripotent stem cell (hPSC) lines are generated, exchanged, and implemented. Ideally, a single name should be used as a generally applied reference for each cell line to access and unify cell-related information across publications, cell banks, cell registries, and databases and to ensure scientific reproducibility. We discuss the needs and requirements for such a unique identifier and implement a standard nomenclature for hPSCs, which can be automatically generated and registered by the human pluripotent stem cell registry (hPSCreg). To avoid ambiguities in PSC-line referencing, we strongly urge publishers to demand registration and use of the standard name when publishing research based on hPSC lines.
cell data referencing, cell databases, cell line authentication, cell line nomenclature, human pluripotent stem cells, stem cell registry
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Copyright 2017 The Authors. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
DOI of Published Version
Stem Cell Reports. 2018 Jan 9;10(1):1-6. doi: 10.1016/j.stemcr.2017.12.002. Link to article on publisher's site
Stem cell reports
Kurtz, Andreas; Seltmann, Stefanie; and Smith, Kelly P., "A Standard Nomenclature for Referencing and Authentication of Pluripotent Stem Cells" (2018). Open Access Articles. 3371.
Creative Commons License
This work is licensed under a Creative Commons Attribution-Noncommercial-No Derivative Works 4.0 License.