UMMS Affiliation

International Stem Cell Registry; Department of Neurology

Publication Date

2018-01-09

Document Type

Article

Disciplines

Cell Biology | Cells | Databases and Information Systems | Laboratory and Basic Science Research

Abstract

Unambiguous cell line authentication is essential to avoid loss of association between data and cells. The risk for loss of references increases with the rapidity that new human pluripotent stem cell (hPSC) lines are generated, exchanged, and implemented. Ideally, a single name should be used as a generally applied reference for each cell line to access and unify cell-related information across publications, cell banks, cell registries, and databases and to ensure scientific reproducibility. We discuss the needs and requirements for such a unique identifier and implement a standard nomenclature for hPSCs, which can be automatically generated and registered by the human pluripotent stem cell registry (hPSCreg). To avoid ambiguities in PSC-line referencing, we strongly urge publishers to demand registration and use of the standard name when publishing research based on hPSC lines.

Keywords

cell data referencing, cell databases, cell line authentication, cell line nomenclature, human pluripotent stem cells, stem cell registry

Rights and Permissions

Copyright 2017 The Authors. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

DOI of Published Version

10.1016/j.stemcr.2017.12.002

Source

Stem Cell Reports. 2018 Jan 9;10(1):1-6. doi: 10.1016/j.stemcr.2017.12.002. Link to article on publisher's site

Journal/Book/Conference Title

Stem cell reports

Comments

Full author list omitted for brevity. For the full list of authors, see article.

Related Resources

Link to Article in PubMed

PubMed ID

29320760

Creative Commons License

Creative Commons Attribution-Noncommercial-No Derivative Works 4.0 License
This work is licensed under a Creative Commons Attribution-Noncommercial-No Derivative Works 4.0 License.

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