UMMS Affiliation

Department of Medicine; Department of Medicine, Division of Gastroenterology

Publication Date


Document Type



Digestive System Diseases | Gastroenterology | Pathological Conditions, Signs and Symptoms


Microscopic colitis (MC) is an inflammatory condition of the large bowel that is associated with chronic, nonbloody diarrhea. Colonoscopy usually demonstrates normal mucosa, while tissue biopsy reveals intraepithelial lymphocytes or a subepithelial collagen band. Although no specific antibody has been discovered, MC is associated with several autoimmune disorders such as celiac disease, Hashimoto's thyroiditis, and rheumatoid arthritis. There are only a small number of case reports documenting possible hereditary MC cases, but up to 12% of patients with MC have a family history of inflammatory bowel disease. Other associations include proton pump inhibitor use, cigarette smoking, HLA-DQ2/86, and possibly some gastrointestinal infections.

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Copyright: © 2017 Fasullo et al. This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. To view a copy of this license, visit

DOI of Published Version



ACG Case Rep J. 2017 Jul 19;4:e87. doi: 10.14309/crj.2017.87. eCollection 2017. Link to article on publisher's site

Journal/Book/Conference Title

ACG case reports journal

Related Resources

Link to Article in PubMed

PubMed ID


Creative Commons License

Creative Commons Attribution-Noncommercial-No Derivative Works 4.0 License
This work is licensed under a Creative Commons Attribution-Noncommercial-No Derivative Works 4.0 License.