UMMS Affiliation

Clinical Pharmacy Services, Commonwealth Medicine

Publication Date


Document Type



Anesthesia and Analgesia | Health Services Administration | Pharmacy and Pharmaceutical Sciences


Objective: To evaluate usage patterns of dexmedetomidine in the operating room after implementation of a prescribing guideline.

Methods: We conducted a retrospective analysis to evaluate the impact of a prescribing guideline on usage patterns of dexmedetomidine in the operating room at a tertiary, academic medical center during one-month period pre- (July 2010) and post-guideline (July 2011 and July 2012) implementation.

Results: A total of 267 patients received intraoperative dexmedetomidine during the study period. Dexmedetomidine use in surgical procedures decreased post-guideline implementation [5.7% (pre) vs. 1.9% and 3.3% (post)]. The most common guideline-based indication for intraoperative dexmedetomidine was for anesthesia during bariatric surgery (41% and 38% in 2011 and 2012, respectively). We estimated a cost-avoidance of $308,856 over the two-year period after guideline implementation.

Conclusion: Our results suggest that implementation of a prescribing guideline for the use of dexmedetomidine in the operating room is feasible and associated with improved utilization patterns.


prescribing guideline, dexmedetomidine, operating room

Rights and Permissions

© 2016 The Authors. Open Access funded by King Saud University.

DOI of Published Version



Saudi Pharm J. 2017 Jan;25(1):144-147. Epub 2016 Jan 14. Link to article on publisher's site

Journal/Book/Conference Title

Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society

Related Resources

Link to Article in PubMed

PubMed ID


Creative Commons License

Creative Commons Attribution-Noncommercial-No Derivative Works 4.0 License
This work is licensed under a Creative Commons Attribution-Noncommercial-No Derivative Works 4.0 License.



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