Division of Rheumatology, Department of Medicine
Complex Mixtures | Musculoskeletal Diseases | Pharmaceutics and Drug Design | Rheumatology
Biosimilars remain a hot topic in rheumatology, and some physicians are cautious about their application in the real world. With many products coming to market and a wealth of guidelines and recommendations concerning their use, there is a need to understand the changing landscape and the real clinical and health-economic potential offered by these agents. Notably, rheumatologists will be at the forefront of the use of biosimilar monoclonal antibodies/soluble receptors. Biosimilars offer cost savings and health gains for our patients and will play an important role in treating rheumatic diseases. We hope that these lower costs will compensate for inequities in access to therapy based on economic differences across countries. Since approved biosimilars have already demonstrated highly similar efficacy, it will be most important to establish pharmacovigilance databases across countries that are adequate to monitor long-term safety after marketing approval.
Anti-TNF, DMARDs (biologic), Economic Evaluations, Rheumatoid Arthritis, Treatment, Biosimilar pharmaceuticals
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DOI of Published Version
Ann Rheum Dis. 2016 Jun;75(6):974-82. doi: 10.1136/annrheumdis-2016-209166. Epub 2016 Mar 8. Link to article on publisher's site
Annals of the rheumatic diseases
Dorner, Thomas; Strand, Vibeke; Cornes, Paul; Goncalves, Joao; Gulacsi, Laszlo; Kay, Jonathan; Kvien, Tore K.; Smolen, Josef S.; Tanaka, Yoshiya; and Burmester, Gerd R., "The changing landscape of biosimilars in rheumatology" (2016). Open Access Articles. 2818.
Creative Commons License
This work is licensed under a Creative Commons Attribution-Noncommercial 4.0 License